• Title/Summary/Keyword: exudate

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Immunopotentiating Activity of Water Extracts of Some Crude Drugs (수종 생약 수침 엑기스의 면역증강 작용에 관한 연구)

  • Kim, Mi-Sook;Lee, Na-Gyong;Lee, Jae-Hyun;Byun, Soon-Jung;Kim, Young-Choong
    • Korean Journal of Pharmacognosy
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    • v.19 no.3
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    • pp.193-200
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    • 1988
  • Immunopotentiating activity of water extract of Lycii Fructus, Rubus Fructus, Torilis Fructus, Schizandrae Fructus and Cuscutae Semen were investigated using mouse fed with normal diet and protein deficient diet. Body weight, ratio of spleen or thymus to body weight, number of total peritoneal exudate cell, content of total serum protein and albumin content were decreased in the mouse fed with protein deficient diets as compared to the mouse fed with normal diet. Regardless of the nutritional condition, the supplement of the water extract of Lycii, Rubus Torilis, Schizandrae Fructus or Cuscutae Semen increased the ratio of spleen to body weight. The increment of this ratio was significant by the supplement of water extracts of Lycii and Torilis Fructus in mouse fed with protein deficient diet. The supplement of water extracts of Torilis Fructus to the mouse fed with protein deficient diet increased the content of total serum protein and albumin content significantly. Similar results were obtained with Lycii, Rubus, Schizandrae Fructus and Cuscutae Similar. The electrophorogram shows the difference in the concentration of some serum protein constituents between the mouse fed with normal diet and protein deficient diet.

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The Anti-inflammatory and Analgesic Activities of Gumiganghwaltang (구미강활탕의 소염.진통작용)

  • Go, Jae-Jong;Park, Jo-Young;Moon, Young-Hee
    • Korean Journal of Pharmacognosy
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    • v.30 no.1
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    • pp.18-24
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    • 1999
  • This study was investigated on anti-inflammatory and analgesic activity on Gu-Mi-Gang-Hwal-Tang which has been used for the treatment of common cold and headache, arthralgia, fever in oriental medicine. The anti-inflammatory activities of Gu-Mi-Gang-Hwal-Tang water extract (GMGHT) on the carrageenin induced edema, acetic acid induced edema, and corton oil induced granuloma pouch in rats were examined. The analgesic effect of the GMGHT was investigated utilizing acetic acid induced writhing syndrome in mice. The antipyretic activity of the GMGHT was also investigated. The oral administration of GMGHT has been shown the anti-inflammatory activities in 1% carrageenin and acetic acid induced edema in rats. The GMGHT has been shown significant inhibitory effects on glanuloma and exudate formation in rats, especially the GMGHT (450 mg/kg) has the efficacy more than the GMGHT (150 mg/kg). The writhing syndromes induced by acetic acid in mice were inhibited, especially analgesic activity of the GMGHT (450 mg/kg) is similar to that of piroxicam and antipyretic activities were recognized in rats. In the present study, the GMGHT is indicated to have the anti-inflammatory, analgesic and antipyretic activities.

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Quality Changes of Salted Baechu with Packaging Methods during Long Term Storage (포장방법을 달리한 절임배추의 장기저장중 품질변화)

  • Han, Eung-Soo;Seok, Moon-Sik;Park, Ji-Hyun
    • Korean Journal of Food Science and Technology
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    • v.30 no.6
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    • pp.1307-1311
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    • 1998
  • Optimal packaging methods for the long term storage of salted winter baechu were investigated. Salted baechu was packaged individually in 20 ㎏ unit weight in LDPE (low density polyethylene), HDPE (high density polyethylene), PVC-box and then stored at $0^{\circ}C$ for 8 weeks. During storage, quality index of salted baechu were measured in terms of salinity, pH, reducing sugar content, total cell counts and lactic acid bacterial counts. Salted baechu deteriorated rapidly in PVC-box, and slowly in HDPE but sustained for 8 weeks in LDPE. In all treatment, salted baechu was maintained better at submerged parts in exudate, but deteriorated at emerged parts.

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Antitumor and Immunological Activities of ${\gamma}$-ray Irradiated Lipopolysaccharide Extracted from proteus vulgaris RH-90 (Proteus vulgaris RH-90에서 추출하여 감마선 조사시킨 Lipopolysaccharide(LPS)의 항암 및 면역활성에 미치는 영향)

  • 류병호;박우열김희숙박종옥
    • KSBB Journal
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    • v.6 no.1
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    • pp.45-54
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    • 1991
  • The aims of this study were investigated the antitumor effects and immunological activities of lipopolysaccharides (LPS) extracted from Proteus vulgaris RH-90 toward sarcoma-180 cells. LPS extracted from Proteus vulgris RH-90 was irradiated with gamma ray for detoxification. The tumor incidence of sarcoma-180 occurs all group which injected with gamma ray irradiated LPS and tumor of sarcoma-180 was necrotized with breeding in the injected group of l0$\mu\textrm{g}$ LPS. The inhibition ratio of tumor growth showed at the highest level of 60.88% when 5$\mu\textrm{g}$ gamma ray irradiated LPS was injected into mice. The prolongation ratio of life showed 20.72% when injected into mice with gamma ray irradiated LPS of 5$\mu\textrm{g}$. In the effect of immunological activity, the number of circurating leucocyte and peritoneal exudate cells were increased significantly in the treatment group than that control group, and dose-dependent response indicated by the increase of weights of immunorgans which revealed the improvement of immunity. The effect of macrophage on phagocytes, there were not found the differences between phagocytic and corrected phagocytic index.

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Anti-Inflammatory, Analgesic and Antipyretic Actions of Mahaengeuigam-Tang (마행의감탕의 소염.진통.해열작용)

  • Roh, Eun-Mi;Moon, Young-Hee
    • Korean Journal of Pharmacognosy
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    • v.32 no.3 s.126
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    • pp.242-247
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    • 2001
  • The anti-inflammatory activity of water extract of Mahaengeuigam-Tang(MHEGTWE) was examined using the carrageenin and acetic acid induced edema, croton oil induced granuloma pouch, and adjuvant arthritis in rats. In addition, the acute toxicity, analgesic and antipyretic effects of MHEGTWE were investigated by the general experimental methods. In acute toxicity test in mice, MHEGTWE showed 10% mortality at 2400 mg/kg(p.o), but it did not showed at 1200 mg/kg(i.p). It was also showed significant analgesic action on the writhing syndrome induced by 0.7% acetic acid at 600 mg/kg(p.o) and its antipyretic activity was observed in the typhoid vaccine induced fevered rats at 300 mg/kg(p.o). By the oral administration of the MHEGTWE, the significant anti-inflammatory activity was observed on 1% carrageenin induced edema, and it significantly inhibited the granuloma and exudate formation in rats. In the adjuvant arthritis experiment, the MHEGTWE decreased the hind paw edema in rats for 19 days. The results suggest that MHEGTWE has analgesic, anti-inflammatory and antipyretic action.

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Effect of Green-Manure Crop Rotation on Weed Control (녹비작물을 이용한 윤작이 잡초 제어에 미치는 영향)

  • Lee, Sang-Min;Lee, Byung-Mo;Lee, Youn;Lee, Yong-Hwan;Sung, Jwa-Kyung;Yun, Hong-Bae;Choi, Hyun-Sug
    • Korean Journal of Organic Agriculture
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    • v.20 no.2
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    • pp.201-209
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    • 2012
  • This study was conducted to evaluate the effects of crop rotation on the weed occurrence in green onion and red pepper cultivation. Rye and hairy vetch were annually seeded for winter season. The reduction of weed germination was pronounced by about 50% in green onion field, but was not significant in red pepper field through rye cropping. Among weed species, the germination of Abutilon theophrasti, Cyperus iria and Digitaria ciliaris was distinctly inhibited by exudate of rye root, but not by that of hairy vetch in vitro experiment. The return of rye biomass into onion field decreased amount of weed biomass but increased index of weed diversity.

랫드의 간질성 폐염

  • Hyeon, Gang-Bu
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2002.11a
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    • pp.12-20
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    • 2002
  • 1. 질병명 : Interstitial pneumonia 2. 본질명의 개요 역사 및 역학 Michael R Elwell, Joel F Mahler, G N Rao: “ Have You Seen This\ulcorner" ; Inflammatory Lesions in the Lungs of Rats. Toxicologic Pathology, 25: 529-531, 1997. Male and female F344 rats, approximately 19 weeks old, from prechronic toxicity studies performed for NTP/NIEHS over a period of several years at different laboraories located throughout the US. The rats were supplied by 2 different production colonies located in the eastern and western areas of the US. Gross findings ㆍ In some rats the lesions were noted as pale or tan foci in the lungs Microscopic findings ㆍ A prominent increase in perivascular lymphocytes ㆍ A variable increase in the amount of peribronchiolar lymphoid tissues ㆍ Frequently an inflammatory cell exudate within the alveolar spaces ㆍ Focal hyperplasia of alveolar type 2 cells Similar lung lesions were not observed in B6C3F1 mice concurrently on study with affected rats. Similar lung lesions were not observed in F344 rats at the end of 2-year NTP studies. Virus, mycoplasma, bacterial serology, bacterial culture, protozoal identification: negative EM: ㆍ No virus particles were identified. ㆍ Rod shaped bacteria were observed in the alveolar spaces. ㆍ Bacteria were not observed in the bronchi/ bronchioles of rats with alveolar organism. (omitted)

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The Review of the Blood-Letting Therapy in the Zhenjiudacheng (침구대성에 나타난 자락요법에 대한 고찰)

  • Kwon, Young-Wan;Lee, Sang-Ryong
    • Korean Journal of Acupuncture
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    • v.34 no.4
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    • pp.231-240
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    • 2017
  • Objectives : This study was designed to establish the basis for expanding the indications for Blood-letting therapy by reviewing the contents recorded in the Zhenjiudacheng. Methods : Articles associated with the Blood-letting therapy were categorized according to the factors such as the characteristics of the treatment site, the used instruments, the caution, the side effects, the diseases, the acupoints, etc. Results : 1. The characteristics of treatment site were the red, purple, purplish red, purplish black color and the localized collection of fibrous exudate. 2. There were several instruments used for Blood-letting therapy; Samreongchim, Sochim, Loguan, Stone needle, Jukyeop, etc. 3. Several cautions and side effects of the Blood-letting therapy were recorded in the Zhenjiudacheng. 4. The Blood-letting therapy could be performed for a broad spectrum of symptoms such as headaches, backaches, schizophrenia, hyperemia, etc. 5. Not only acupoints but also extra points were used for blood-Letting therapy. 6. In addition to the usual Blood-letting region, Blood-letting therapy was performed directly on the pathologic site and pathologic reaction site. Conclusions : In the Zhenjiudacheng, Blood-letting therapy was described in a concrete and substantive manner in order to enable practical clinical application.

Studies on immunomodulating Function of Components Separated from Platycodi Radix (길경의 면역조절 기능성에 관한 연구)

  • Bae, Man-Jong;Park, Mu-Hui;Son, Gyu-Mok
    • The Korean Journal of Food And Nutrition
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    • v.9 no.1
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    • pp.69-75
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    • 1996
  • In order to research for compound of immunomodulatic and anti-allergic function. These experiments were conducted to investigated the effects of hot water extracts(PRWE) , ethanol extracts (PREE) and polysaccharide fraction extracts (PRPE) extracted from platycodi radix on immune response. The effect of these platycodi radix extracts on hemagglutinin titer(HA), hemalysin titer(HY), plaque forming cell(PFC), rosette forming cell (RFC) and phagocytosis was Investigated by using BALB / C mice. The results obtained from this study are as follows. Generally, the oral administration of extracts fractions for 10 days each other resulted in the enhanced HA and HY. In the experiment of PFC and RFC, the results of experimental groups which was given each samples compared to control group showed the enhanced level of activity such as PRPE 160% and 196% each other But PRWE and PREE decreased or wear not changed. When PREE, PRPE or PRWE was given to mice orally, PREE and PRPE significantly enhanced the phagocytic activity of peritoneal exudate cells(PEC), spleen cells(SC) and monolymphocytus cell(MC), about from 150% to 250%, but PRW was decreased.

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Bacterial Canker of Japanese Apricot (Prunus mume) Caused by Pseudomonas syringae pv. morsprunorum (Pseudomonas syringae pv. morsprunorum에 의한 매실의 세균성궤양성)

  • Kim Doo Young;Han Hyo Shim;Koh Young Jin;Jung Jae Sung
    • Research in Plant Disease
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    • v.11 no.2
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    • pp.135-139
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    • 2005
  • Bacterial canker of Japanese apricot (Prunus mume Sieb. et Zucc.) was found in all orchards located at southern area of Korea. Typical symptoms were characterized by dark spots formed on fruits, brown lesions on leaves, and bacterial exudate oozed out of the cracked bark of diseased tree. Thirty-eight isolates from 16 different areas were identified on the basis of biochemical and physiological characteristics (LOPAT and GATTa test) and also on the basis of 165 rDNA and ITS sequences. Pathogenicity tests confirmed that bacterial canker of Japanese apricot in Korea is caused by Pseudomonas syringae pv. morsprunorum.