• Title/Summary/Keyword: extensions

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Activation of peroxisome proliferator-activated receptor gamma induces anti-inflammatory properties in the chicken free avian respiratory macrophages

  • Mutua, Mbuvi P.;Steinaa, Lucilla;Shadrack, Muya M.;Muita, Gicheru M.
    • Journal of Animal Science and Technology
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    • v.57 no.11
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    • pp.40.1-40.7
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    • 2015
  • Background: Activation of peroxisome proliferator activated receptor gamma ($PPAR{\gamma}$) in the alveolar macrophages (AM) by selective synthetic $PPAR{\gamma}$ ligands, improves the ability of the cells to resolve inflammation. In birds, respiratory macrophages are known as free avian respiratory macrophages (FARM) and show distinct functional differences from AM. The effects of treating FARM with $PPAR{\gamma}$ ligands are unclear. Methods: FARM were harvested by lavage of chicken respiratory tract and their morphology assessed at microscopic level. The effects of $PPAR{\gamma}$ agonists on the FARM in vitro viability, phagocytic capacity and proinflammatory cytokine (TNF-${\alpha}$) production were assessed. Results: FARM had eccentric nucleus and plasma membrane ruffled with filopodial extensions. Ultrastructurally, numerous vesicular bodies presumed to be lysosomes were present. FARM treated with troglitazone, a selective $PPAR{\gamma}$ agonist, had similar in vitro viability with untreated FARM. However, treated FARM co-cultured with polystyrene particles, internalized more particles with a mean volume density of 41 % compared to that of untreated FARM of 21 %. Further, treated FARM significantly decreased LPS-induced TNF-${\alpha}$ production in a dose dependent manner. Conclusion: Results from this study show that $PPAR{\gamma}$ synthetic ligands enhance phagocytic ability of FARM. Further the ligands attenuate production of proinflammatory cytokines in the FARM, suggesting potential therapeutic application of $PPAR{\gamma}$ ligands in the management of respiratory inflammatory disorders in the poultry industry.

An Analysis of Geography, Biography and History Class in UDC and Some Suggestions on their Applicable Principles into KDC (UDC 지리.전기.역사류의 특성과 KDC 에서의 적용 방안)

  • 이창수
    • Journal of Korean Library and Information Science Society
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    • v.34 no.3
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    • pp.125-145
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    • 2003
  • The core version of UDC(Universal Decimal Classification) is available in an electronic form called MRF(Master Reference File) which supports the maintenance of the quality of the scheme as a working tool for the UDCC(UDC Consortium) by annual reviewing its content and initiating revisions and extensions. In this paper, we discuss outcomes of our in-depth analysis of the geography, biography and history disciplines in UDC focused on the its evolutions and characteristics, including the common auxiliaries of place, the common auxiliaries of time and the common auxiliaries of race, ethnic grouping and nationality. Based on the in-depth analysis, we suggested some ideas which can be applied into the history class of KDC(Korean Decimal Classification). In particular, its principle of combination methods in the history of individual regions, the way of its assignment of physical geography and human geography in the same division, the possibilities of the extension of the table of geographical division and the adaptation of the table of chronological division in KDC.

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Perceived Fit and Brand Value Transfer in Luxury Fashion Brand Extension (럭셔리 패션브랜드 확장시 지각된 적합성과 브랜드 가치전이)

  • Kim, Eun-Young;Park, Eun-Joo
    • Korean Journal of Human Ecology
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    • v.21 no.1
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    • pp.151-163
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    • 2012
  • The purpose of this study was to examine the effects of perceived fit and brand transfer on extension evaluation in luxury fashion brands. The instrument for this research was a self-administered questionnaire based on a previously developed scale. The variables addressed in this scale included perceived fit, brand value for both parent brand (clothing) and extension brand (home line), extension brand association, and purchase intention of the product in extension brands. The participants in this research comprised of 215 female consumers between the ages of 19 and 51 demographically distributed nationwide. Data were analyzed by descriptive statistics, paired t-test, factor analysis, and regression analysis via SPSS 12.0. Findings showed that brand value consisted of two factors: cognitive and hedonic value in luxury fashion brands. Parent brand value was significantly related to perceived fit with a positive effect on brand association and hedonic value in extension brands. With respect to brand transfer, cognitive value of the parent brand increased the extension brand's cognitive value, while hedonic value of the parent brand increased the extension brand's hedonic value. In addition, purchase intention of the product in the extension brands was determined by the perceived fit and hedonic value of extension brands. This study also discusses the managerial implications for marketers in developing effective luxury brand extensions into new product categories, which leads to a synergy effect in building brand equity in the luxury fashion market.

Efficiency Analysis of Public Service Organizations Using Stochastic Frontier Analysis (확률변경분석을 이용한 공공서비스 조직의 효율성 분석)

  • Shin, Jong Seop;Kim, Hyun Jung
    • Journal of the Korean Operations Research and Management Science Society
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    • v.40 no.1
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    • pp.117-128
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    • 2015
  • An organization must restructure itself once it makes outsourcing decisions. Outsourcing is a strategy that a company adopts to direct internal efforts into strengthening its core business processes while contracting other companies for strategically less critical tasks thereby improving organizational production efficiency, and the strategy inevitably involves organizational restructuring. While public service organizations have increasingly embraced outsourcing as well, only a handful of studies analyze the change in efficiency from organizational restructuring. Therefore, this study uses Stochastic Frontier Analysis (SFA) to test whether efficiency improved in Korea Expressway Corporation's restructured branch offices. Korea Expressway Corporation evaluated and grouped its branches based on road extensions management, traffic volume, the number of snow days, road deterioration, and the number of junctions to differentially allocate its personnel and budget. The extent of efficiency improvement in each group was compared, and results show that inefficiency did not exist in any of the groups. The efficiency index among the three group categories was similar across the board; 9 offices in the A-group with its expanded personnel and budget had an efficiency index of 0.954, 12 offices in the B-group with unchanged personnel and budget conditions had an index of 0.950, and 12 offices in the C-group with reduced personnel and budget had an index of 0.937. SFA facilitates efficiency analyses because it does not require pre-restructuring data. This study is easy to apply in practice and empirically tests efficiency improvement in organizational restructuring based on data collected from all the branch offices in Korea Expressway Corporation.

Aerodynamic control capability of a wing-flap in hypersonic, rarefied regime: Part II

  • Zuppardi, Gennaro;Vangone, Daniele
    • Advances in aircraft and spacecraft science
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    • v.4 no.5
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    • pp.503-514
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    • 2017
  • The attitude control of an aircraft is usually fulfilled by means of thrusters at high altitudes. Therefore, the possibility of using also aerodynamic surfaces would produce the advantage of reducing the amount of fuel for the thrusters to be loaded on board. For this purpose, Zuppardi already considered some aerodynamic problems linked to the use of a wing flap in a previous paper. A NACA 0010 airfoil with a trailing edge flap of 35% of the chord, in the range of angle of attack 0-40 deg and flap deflections up to 30 deg was investigated. Computer tests were carried out in hypersonic, rarefied flow by a direct simulation Monte Carlo code at the altitudes of 65 and 85 km of Earth Atmosphere. The present work continues this subject, considering the same airfoil and free stream conditions but two flap extensions of 45% and 25% of the chord and two flap deflections of 15 and 30 deg. The main purpose is to compare the influence of the flap dimension with that of the flap deflection. The present analysis is carried out in terms of: 1) percentage variation of the global aerodynamic coefficients with respect to the no-flap configuration, 2) increment of pressure and heat flux on the airfoil lower surface due to the Shock Wave-Shock Wave Interaction (SWSWI) with respect to the same quantities with no SWSWI or in no-flap configuration, 3) flap hinge moment. Issues 2) and 3) are important for the design of the mechanical and thermal protection system and of the flap actuator, respectively. Under the above mentioned test and geometrical conditions, the flap deflection is aerodynamically more effective than the flap extension, because it involves higher variation of the aerodynamic coefficients. However, tests verify that a smaller deflection angle involves the advantage of a smaller increment of pressure and heat flux on the airfoil lower surface, due to SWSWI, as well as a smaller hinge moment.

Seasonal Variations of Water Mass Distributions and Their Causes in the Yellow Sea, the East China Sea and the Adjacent Seas of Cheju Island (황해, 동지나해와 제주도 주변해역에서의 해수분포의 계절변화와 그 원인)

  • PANG Ig-Chan;RHO Hong-Kil;KIM Tae-Hee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.25 no.2
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    • pp.151-163
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    • 1992
  • Seasonal variations of water mass distributions in the Yellow Sea, the East China Sea, and the adjecent seas of Cehju Island, are investigated. A common seasonal variation over these whole areas is shown. Warm and saline waters are extended northwestward into the Yellow Sea in winter and retreated back southeastward to the East China Sea in summer. Barotropic numerical model results suggest that monsoon winds could drive such seasonal variations. Upwind flows play an important role in the processes. In the numerical model results, upwind flows are shifted to China. It is due to energy dissipations by complicated coast lines and shallow bottom topographies in the northern part of the Yellow Sea. The shifted routes of upwind flows agrees well with that of the southward extensions of the Yellow sea Bottom Cold Waters in summer.

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Phenomenological Modeling of Newly Discovered Eclipsing Binary 2MASS J18024395 + 4003309 = VSX J180243.9+400331

  • Andronov, Ivan L.;Kim, Yonggi;Kim, Young-Hee;Yoon, Joh-Na;Chinarova, Lidia L.;Tkachenko, Mariia G.
    • Journal of Astronomy and Space Sciences
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    • v.32 no.2
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    • pp.127-136
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    • 2015
  • We present a by-product of our long term photometric monitoring of cataclysmic variables. 2MASS J18024395 +4003309 = VSX J180243.9 +400331 was discovered in the field of the intermediate polar V1323 Her observed using the Korean 1-m telescope located at Mt. Lemmon, USA. An analysis of the two-color VR CCD observations of this variable covers all the phase intervals for the first time. The light curves show this object can be classified as an Algol-type variable with tidally distorted components, and an asymmetry of the maxima (the O'Connell effect). The periodogram analysis confirms the cycle numbering of Andronov et al. (2012) and for the initial approximation, the ephemeris is used as follows: Min I. BJD = 2456074.4904+0.3348837E. For phenomenological modeling, we used the trigonometric polynomial approximation of statistically optimal degree, and a recent method "NAV" ("New Algol Variable") using local specific shapes for the eclipse. Methodological aspects and estimates of the physical parameters based on analysis of phenomenological parameters are presented. As results of our phenomenological model, we obtained for the inclination $i=90^{\circ}$, $M_1=0.745M_{\odot}$, $M_2=0.854M_{\odot}$, $M=M_1+M_2=1.599M_{\odot}$, the orbital separation $a=1.65{\cdot}10^9m=2.37R_{\odot}$ and relative radii $r_1=R_1/a=0.314$ and $r_2=R_2/a=0.360$. These estimates may be used as preliminary starting values for further modeling using extended physical models based on the Wilson & Devinney (1971) code and it's extensions

3D Modeling of Safety Leg Guards Considering Skin Deformation and shape (피부길이변화를 고려한 3차원 다리보호대 모델링)

  • Lee, Hyojeong;Eom, Ran-i;Lee, Yejin
    • Korean Journal of Human Ecology
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    • v.24 no.4
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    • pp.555-569
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    • 2015
  • During a design process of a protective equipment for sports activities, minimizing movement restrictions is important for enhancing its functions particularly for protection. This study presents a three-dimensional(3D) modeling methodology for designing baseball catcher's leg guards that will allow maximum possible performance, while providing necessary protection. 3D scanning is performed on three positions frequently used by a catcher during the course of a game by putting markings on the subject's legs at 3cm intervals : a standing, a half squat with knees bent to 90 degrees and 120 degrees of knee flexion. Using data obtained from the 3D scan, we analyzed the changes in skin length, radii of curvatures, and cross-sectional shapes, depending on the degree of knee flexion. The results of the analysis were used to decide an on the ideal segmentation of the leg guards by modeling posture. Knee flexions to 90 degrees and to $120^{\circ}$ induced lengthwise extensions than a standing. In particular, the vertical length from the center of the leg increases to a substantially higher degree when compared to those increased from the inner and the outer side of the leg. The degree of extension is varied by positions. Therefore, the leg guards are segmented at points where the rate of increase changed. It resulted in a three-part segmentation of the leg guards at the thigh, the knee, and the shin. Since the 120 degree knee-flexion posture can accommodate other positions as well, the related 3D data are used for modeling Leg Guard (A) with the loft method. At the same time, Leg Guard (B) was modeled with two-part segmentation without separating the knee and the shin as in existing products. A biomechanical analysis of the new design is performed by simulating a 3D dynamic analysis. The analysis revealed that the three-part type (A) leg guards required less energy from the human body than the two-part type (B).

Maximizing Concurrency and Analyzable Timing Behavior in Component-Oriented Real-Time Distributed Computing Application Systems

  • Kim, Kwang-Hee Kane;Colmenares, Juan A.
    • Journal of Computing Science and Engineering
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    • v.1 no.1
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    • pp.56-73
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    • 2007
  • Demands have been growing in safety-critical application fields for producing networked real-time embedded computing (NREC) systems together with acceptable assurances of tight service time bounds (STBs). Here a service time can be defined as the amount of time that the NREC system could take in accepting a request, executing an appropriate service method, and returning a valid result. Enabling systematic composition of large-scale NREC systems with STB certifications has been recognized as a highly desirable goal by the research community for many years. An appealing approach for pursuing such a goal is to establish a hard-real-time (HRT) component model that contains its own STB as an integral part. The TMO (Time-Triggered Message-Triggered Object) programming scheme is one HRT distributed computing (DC) component model established by the first co-author and his collaborators over the past 15 years. The TMO programming scheme has been intended to be an advanced high-level RT DC programming scheme that enables development of NREC systems and validation of tight STBs of such systems with efforts far smaller than those required when any existing lower-level RT DC programming scheme is used. An additional goal is to enable maximum exploitation of concurrency without damaging any major structuring and execution approaches adopted for meeting the first two goals. A number of previously untried program structuring approaches and execution rules were adopted from the early development stage of the TMO scheme. This paper presents new concrete justifications for those approaches and rules, and also discusses new extensions of the TMO scheme intended to enable further exploitation of concurrency in NREC system design and programming.

SMIL Extensions for Representation and Streaming of Lecture Contents (원격강의 컨텐츠의 표현과 스트리밍을 위한 SMIL 확장에 대한 연구)

  • 최용준;정상준;권은영;구자효;김종근
    • Journal of Korea Multimedia Society
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    • v.6 no.3
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    • pp.527-538
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    • 2003
  • The contents of remote lectures are written by authoring tools or animation tools. Written contents then integrate existing medias, and are stored in a file type, which is added to the lecturing activities of lecturers. These files are stored according to the kinds of each authoring tool. So, there is no interchangeability and the efficiency of each media is not so good. Due to these structural features, it is not possible to do streaming lectures in on-line environments. In this study, a technique was suggested, which guarantees the interchangeability of remote lecturing contents using SMIL which is a synchronizing multimedia language. The suggested technique is an extended type of SMIL, and includes tags to represent the lectures of tutors which are the specific feature of remote lectures. Additionally, a model, which does streaming SMIL remote lecture contents through on-line, and which transfers control techniques are suggested. The remote lecture contents established by the proposed method can be applied to all authoring tools for remote lectures just by installing conversion modules, and can be a kind of expression model of the synchronizing model for streaming service in on-line environment.

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