• Title/Summary/Keyword: exposed times

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Effects of Chitosan on the Lead Level and Histological Changes in Rats Exposed to Various Levels of Lead (납에 노출된 흰쥐의 혈액과 조직의 납 함량 및 병변에 대한 키토산의 섭취효과)

  • Park Joo Ran;Kim Mee hye;Lee Yeon Sook
    • Journal of Nutrition and Health
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    • v.38 no.1
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    • pp.48-55
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    • 2005
  • Chitosan, which is a biopolymer, composed of glucosamine units linked by $\beta$-1, 4 glycoside bonds, is rich in shells of crustacean such as crabs and shrimps. Consumption of chitosan has been rapidly increased as a functional food. We examined effects of chitosan on the damages caused by lead (Pb) exposure in rats. Male Sprague-Dawley rats were divided into 8 groups (n = 64), then fed diets containing 3% cellulose (control) or 3% chitosan, each with 4 different lead doses (0 mg/d, 20 mg/d, 50 mg/d, and 100 mg/d) for 4 wks. Lead doses were given 3 times per week by oral administration. Blood lead levels in rats increased depending on the administered doses of lead. Rats fed chitosan diets showed lower blood lead concentration than did their respective controls. Effect of chitosan on the blood lead was more beneficial in rats exposed to lower lead (20 mg/d) than in rats exposed to higher lead (50 mg/d and 100 mg/d). Histological changes in erythrocytes and liver were also examined. Chitosan tended to reduce numbers of basophilic stippling erythrocytes and improve the histological liver changes in rats given various lead doses. The preventive effects of chitosan on liver damages were stronger in rats with higher lead than those with lower lead. These results indicate that chitosan has beneficial effects on both blood toxicological responses and histological damages of erythrocytes and liver induced by the administration of various lead doses.

Responses of Renal Mixed Function Oxidase System in Rockfish (Sebastes schlegeli) Administered with 4-Nonylphenol (노닐페놀을 주사한 조피볼락의 신장 MFO (mixed function oxidase)의 반응)

  • JEON Joong-Kyun;LEE Ji-Seon;SOHN Young-Chang;HONG Gyong-Pyo;SHIM Won Joon;KIM Pyong-Kih;HAN Chang-Hee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.36 no.6
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    • pp.573-577
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    • 2003
  • Effects of 4-nonylphenol (4-NP) on mixed function oxygenase (MFO) in the kidneies of rockfish (Sebastes schlegeli) were investigated. The cytochrome P45O (CYP) contents and NADPH cytochrome P450 reductase, NADH cytochrome b5 reductase and 7-ethoxyredorufin-O-deethylase (EROD) activities of microsome, glutathione S-transferase (GST) activity of cytosol in rockfish exposed to 4-NP for 7 days using an intraperitoneal injection (25 mg/kg) were quantitatively determined. The GST activity of rockfish exposed to 4-NP were higher, up to 5.2 times higher, than those in the control fish. The activities of NADPH-and NADH-dependent reductases were inhibited. On the other hand, CYP contents and EROD activity of the 4-NP exposed fish demonstrated neither an increasing or decreasing trend.

Effects of Carbon nanotube Incorporation on the Mechanical Recovery of Portland Cement Paste Exposed to High Temperatures (탄소나노튜브의 혼입량 변화가 고온에 노출된 시멘트 페이스트의 역학적 성능 회복에 미치는 영향)

  • Suh, Heong-Won;Park, Tae-Hoon;Bae, Sung-Chul
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2019.05a
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    • pp.114-115
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    • 2019
  • When concrete is exposed to fire, the decomposition of Portland cement paste results in critical damage to the concrete structure of a building. Although the behavior of cement pastes after heating provides crucial information with respect to the reuse of the building exposed to fire, the recovery process of the damaged concrete structure has not yet been fully elucidated. In addition, research on appropriate additives such as carbon nanotube (CNT) has been increasing recently, however, investigation of CNT incorporated cement paste after decomposition of CNT by high temperature is not fully investigated. In this study, we investigated the physicochemical properties of CNT incorporated cement paste under different temperatures (200℃, 500℃ and 800℃). Also, the effects of different rehydration conditions (20℃ 60% RH and in water for different curing times) on the recovery of the paste were studied. The changes in tensile and compressive strength, surface observation of the specimens were characterized. In addition, the decomposition and formation of hydrates in the paste due to the heating process were studied using X-ray diffraction.

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Thermal Diary - 24 hours' Exposed Temperature and Thermal Comfort in Urban Life, Summer (여름철 도시의 일상생활에서 폭로되는 환경온도와 온냉감 평가)

  • 이민정;전정윤
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2002.11a
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    • pp.333-337
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    • 2002
  • All the outdoor and indoor spaces are connected with each other. The human being moves toward those spaces and experiences temperature fluctuation between the natural and artificial temperature. We conducted an experiment which subjects are the college students wearing the data logger in urban life, and measured 24 hours' exposed temperature and thermal comfort in summer. Results were as follows. 1. Most subjects get weather information(84.6%). Fashion(46.2%) and weather (30.8%) are the reasons to select clothes. They spend their time in indoor environment for 84.92% hours of a day and have an air-conditioner(61.5%) in their houses. 2. Exposed temperature fluctuation were from 33.8$^{\circ}C$ to 15.6$^{\circ}C$. The median value of experienced temperature were 26-27$^{\circ}C$ and average temperature was 26.3$^{\circ}C$. Subjects experienced cold shock of 3.96 times in a day and 67.21% of all evaluated thermal comfort in the range of -1 and 1 by ASHRAE 7 Category Scales. Artificial environment which connected with outside let people experienced temperature fluctuation in wide range.

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A Study on Characteristic of Forest Vegetation and site in Mt. Odae(II) - Site of Plant community in Tongdaesan - (오대산(五臺山)의 산림식생(山林植生)과 입지특성(立地特性)에 관한 연구(硏究)(II) - 동대산(東臺山) 식물군락(植物群落)의 입지특성(立地特性) -)

  • Yee, Sun
    • Journal of Korean Society of Forest Science
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    • v.89 no.5
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    • pp.552-563
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    • 2000
  • The aim of this study was to characterize the forest vegetation and site of Odaesan National Park for ecological forest management. The vegetation could be divided into two forest community groups, seven forest communities, and several subcommunities. South exposed, dry slopes were covered with forests of the Quercus mongolica-Acer pseudosieboldianum community group. Quercus mongolica-Acer pseudosieboldianum community group could be subdivided into ${\bullet}$ Rhododendron mucronulatum var. ciliatum community on dry sites, especially on south or south-westly exposed ridges or convex slopes; ${\bullet}$ Lespedeza${\times}$tomentella community on south exposed slopes, at low altitudes in the eastern part of the study area; ${\bullet}$ Carex humilis-Maackia amurensis community on south exposed slopes up to the montane region; ${\bullet}$ Quercus mongolica-Acer pseudo-sieboldianum typical community on south exposed middle and low slopes, and on upper and middle north exposed slopes; ${\bullet}$ Pimpinella brachycarpa community, preferably on moderately moist and cool sites. On north exposed, more humid and moist sites, forests of the Dryopteris crassirhizoma-Cornus controversa community group were found. This group was subdivided into ${\bullet}$ Acer tschonoskii var. rubripes-Acer tegmentosum community on moderately moist to moist, loamy soils on shady slopes; ${\bullet}$ Deutzia glabrata-Ulmus laciniata community on north exposed slopes with rocky soil and boulders, having high humidity. There are several rare and endangered species in Rhododendron mucronulatum var. ciliatum community, Carex humilis-Maackia amurensis community, Vicia venosa var. cuspidata subcommunity and Saxifraga punctata subcommunity, and the communities were located in azonal areas in topography. To protect the species, the areas should be categorized as an absolute conservation area, and any forest working should be prohibited in this area.

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Urinary S-Phenylmercapturic Acid as a Biomarker for Biological Monitoring in Workers Exposed to Benzene (벤젠 노출 근로자의 생물학적 모니터링 지표로서의 요중 S-Phenylmercapturic Acid에 관한 연구)

  • Bang, Sin Ho;Kim, Kwang Jong;Yum, Yong Tae
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.6 no.2
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    • pp.272-280
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    • 1996
  • This study was to evaluate the associations between urinary S-Phenyl-mercapturic acid(S-PMA) as a new indicator of biological monitoring for low level of exposure to benzene and independent variables such as the air concentration of benzene in the breathing zone of workers, the years of work, and smoking. In this study the subjects were the total of 145 drawn from 53 workers who were occupationally exposed to benzene and 92 workers who were not. The results were as follows: 1. In the workplace geometric mean concentration of benzene in the breathing zone of workers was 0.31 ppm(0.02 - 3.26 ppm) for the spraying workers and 0.25 ppm(0.02 - 3.95 ppm) for the printing workers. 2. The geometric mean of uninary S-PMA for non exposed group was $8.9{\mu}g/g$ creatinine($0.6-72.3{\mu}g/g$ creatinine), 80.3% (74 workers) of the total non-exposed workers indicated less than $20{\mu}g/g$ creatinine of uninary S-PMA. The difference of uninary S-PMA by sex, age, smoking was not significant. 3. The geometric mean of urinary S-PMA for workers who were exposed to benzene was $37.2{\mu}g/g$ creatinine, and was four times higher than that of workers who were not exposed. And 79.3% (42 workers) of the total exposed workers indicated more than $20{\mu}g/g$ creatinine of urinary S-PMA. 4. Regarding the level of benzene in the air, urinary S-PMA was the highest level of $147.9{\mu}g/g$ creatinine in the workers who were exposed to air concentration of 0.5 ppm of benzene and was higher as the level in the air was increased. 5. The correlation coefficient between log urinary S-PMA and log benzene concentration in the breathing zone was 0.80, and the following linear equation was found between urinary log S-PMA and log benzene concentration in the breathing zone : log S-PMA(${\mu}g/g$ creatinine) = 0.564 log benzene in air(ppm) + 0.192 (n=53, r=0.80, p=0.000) In conclusion, the concentration of S-PMA in urine proved to be good parameter for biological monitoring benzene exposure at the workplace even at low level of benzene in air.

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Lack of connexin 32 does not enhance the benzene-induced hematotoxicity and hemopoietic tumor incidence in mice

  • Yoon, Byung-IL
    • Korean Journal of Veterinary Research
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    • v.45 no.4
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    • pp.517-525
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    • 2005
  • This study was performed to evaluate using wild-type (WT) and $C{\times}32$ knockout (KO) mice if lack of cell to cell communication by connexin 32 gap junction enhances the benzene-induced hematotoxicity and hemopoietic tumor development. The WT and $C{\times}32$ KO mice were exposed to 300 ppm of benzene for 6 hours/day, 5 days/week for a total of 26 weeks by inhalation, and then sacrificed to evaluate the toxicities of hemopoietic organs or allowed to live out their life span to evaluate the hemopoietic tumor incidence. The significant increase and decrease of organ weight were respectively noted in spleen and thymus of both WT and $C{\times}32$ KO mice without significant difference between the genotypes. Histopathologically, benzene exposure for 26 weeks induced the morphological changes in hemopoietic organs, characterized by fat cell accumulation in the bone marrow and extramedullary hemopoiesis in the spleen. The fat cell accumulation was, compared with that of WT mice, considerably exacerbated in the $C{\times}32$ KO mice. However, no significant difference was observed in the changes of hematological values and bone marrow cellularity as well as in the onset and incidence of hemopoietic tumors between WT and $C{\times}32$ KO mice. In conclusion, this study indicated little significant role of the cellular communication by $C{\times}32$ gap junction in the action mechanism of benzene hematotoxicity and leukemogenicity.

Waldorf and Theme-based Program Analyses of Five-year-olds' Activities of Early Childhood Educational Programs (발도르프 프로그램과 생활주제중심 프로그램 유형에 따른 5세 유아의 활동분석)

  • Moon, Chae-Lyun;Chong, Young-Sook
    • Korean Journal of Human Ecology
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    • v.16 no.2
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    • pp.237-250
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    • 2007
  • This study was to provide date for developing a effective educational program which would be helpful for teachers to understand children's daily activities more properly. From two kindergartens, 20 children were observed for 3 consecutive hours. The observer followed the target child, gathering data during 30-second "windows". This observation lasted for three hours per day and each child was observed 60 times. The proportion of major activities such as education, play, work, and conversation in children's daily activities was compared. Results showed that children of Waldorf program were more exposed to and engaged in play than children of Theme-based program, whereas children of theme-based program were exposed to and engaged in academic activities than those of Waldorf program.

Effect of aggregate type on heated self-compacting concrete

  • Fathi, Hamoon;Lameie, Tina
    • Computers and Concrete
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    • v.19 no.1
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    • pp.33-39
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    • 2017
  • In this study, two types of aggregate were used for making self-compacting concrete. Standard cubic specimens were exposed to different temperatures. Seventy-two standard cylindrical specimens ($150{\times}300mm$) and Seventy-two cubic specimens (150 mm) were tested. Compressive strengths of the manufactured specimens at $23^{\circ}C$ were about 33 MPa to 40 MPa. The variable parameters among the self-compacting concrete specimens were of sand stone type. The specimens were exposed to 23, 100, 200, 400, 600, and $800^{\circ}C$ and their mechanical specifications were controlled. The heated specimens were subjected to the unconfined compression test with a quasi-static loading rate. The corresponding stress-strain curves and modulus of elasticity were compared. The results showed that, at higher temperatures, Scoria aggregate showed less sensitivity than ordinary aggregate. The concrete made with Scoria aggregate exhibited less strain. The heated self-compacting concrete had similar slopes before and after the peak. In fact, increasing heat produced gradual symmetrical stress-strain diagram span.

Effect of Sunlight on the Rancidity of Soybean Oil (대두유의 산패에 미치는 일사광선의 영향)

  • 임국이
    • Journal of the Korean Home Economics Association
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    • v.19 no.1
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    • pp.33-37
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    • 1981
  • The accelerating effect of sunlight on the rancidity of soybean oil and the efficacies of several anti-oxidants were measured. The result is as follows: 1. The ac야 value and peroxide value of soybean oil were 0.16 and 1, 72 respectively. 2. the peroxide value of soybean oil which was exposed to sunlight nine hours a day for six days was 134.3: 21 times of that which was not exposed to sunlight. 3. The peroxide value of the soybean oil with 0.02~0.06% BHA decreased a little, but not significantly. 4. The anti-rancidity effect of BHT was a little stronger than BHA. 5. The anti-rancidity effect of ascorbic acid alone was negligible. 6 The peroxide value of soybean oil with an anti-oxidant which comprised ascorbic acid, BHA and BHT decreased to one third of that which was not treated with anti-oxidant.

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