• Title/Summary/Keyword: experimental dynamics

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A Game Theoretic Analysis of Social Commerce Ecosystem at the Crossroads (소셜커머스 생태계의 게임 분석)

  • Kim, Dohoon
    • Asia pacific journal of information systems
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    • v.23 no.2
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    • pp.67-86
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    • 2013
  • This study first provides a stylized model that captures the essential features of the SC (Social Commerce) business and the competition process. The model focuses on the relationship between key decision issues such as marketing inputs and market value. As more SCs join the industry, they are inevitably faced with fierce competition, which may lead to sharp increase in the total marketing and advertising expenditure. This type of competition may lead the industry away from its optimal development path, and at worst, toward a disruption of the entire industry ecosystem. Such being the case, another goal of this study is to examine the possibility that the ToC (Tragedy of the Commons) may occur in the SC industry. We build game models, each of which assumes homogeneity and heterogeneity of SC providers, respectively, and derive explicit equilibrium solutions from both models. Our basic analysis presents Nash equilibria in both models and shows that SC providers are inevitably faced with fierce competition, which may lead to sharp increase in the total marketing expenses. We also compare the game outcomes with one with a hypothetical social planner who determines the total marketing level that optimizes the entire market value. Then, ToC can be defined to describe the situation where the total marketing efforts exceed the socially optimal level of marketing efforts. In both models, we examine the possibility of the ecosystem disruption and specify the conditions under which ToC may occur. However, the chance of avoiding ToC is higher with heterogeneous players than with homogeneous players. To supplement our analytical results, we develop a simulation model which incorporates a market dynamics based on the gap between actual marketing efforts and socially optimal marketing level. Simulation experiments present some lessons and insights which also confirm out findings from equilibrium analysis. For example, heterogeneity in SC providers alleviates the severity of ToC and makes it faster for survivors to escape from the ToC trap. As a result, the degree of industrial concentration tends to increase, which also explains the 'rich-get-richer' phenomenon observed in some empirical studies on the SC industry. Lastly, based on our analytical and experimental results, we come up with some measures to avoid ToC and overcome the shortcomings intrinsic to the current business model. And further discussions provide strategic implications and policy directions to overcome the possible trap of ToC in this ecosystem, and eventually help the industry to sustainably develop itself toward the next level. To name a few examples of policy measures, regulations on the marketing activities so that the overall marketing expenses cannot go beyond the socially optimal level; institutional guidelines and rules to straightening up the distortions in the way that SC providers view the marketing costs (the current marketing costs are underestimated, thereby encouraging SC providers to increase marketing expenditure); and so on.

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Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration

  • Wang, Jianle;Nisar, Majid;Huang, Chongan;Pan, Xiangxiang;Lin, Dongdong;Zheng, Gang;Jin, Haiming;Chen, Deheng;Tian, Naifeng;Huang, Qianyu;Duan, Yue;Yan, Yingzhao;Wang, Ke;Wu, Congcong;Hu, Jianing;Zhang, Xiaolei;Wang, Xiangyang
    • Experimental and Molecular Medicine
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    • v.50 no.11
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    • pp.5.1-5.14
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    • 2018
  • Oxidative stress-induced mitochondrial dysfunction is implicated in the pathogenesis of intervertebral disc degeneration (IVDD). Sirtuin 3 (SIRT3), a sirtuin family protein located in mitochondria, is essential for mitochondrial homeostasis; however, the role of SIRT3 in the process of IVDD has remained elusive. Here, we explored the expression of SIRT3 in IVDD in vivo and in vitro; we also explored the role of SIRT3 in senescence, apoptosis, and mitochondrial homeostasis under oxidative stress. We subsequently activated SIRT3 using honokiol to evaluate its therapeutic potential for IVDD. We assessed SIRT3 expression in degenerative nucleus pulposus (NP) tissues and oxidative stress-induced nucleus pulposus cells (NPCs). SIRT3 was knocked down by lentivirus and activated by honokiol to determine its role in oxidative stress-induced NPCs. The mechanism by which honokiol affected SIRT3 regulation was investigated in vitro, and the therapeutic potential of honokiol was assessed in vitro and in vivo. We found that the expression of SIRT3 decreased with IVDD, and SIRT3 knockdown reduced the tolerance of NPCs to oxidative stress. Honokiol ($10{\mu}M$) improved the viability of NPCs under oxidative stress and promoted their properties of anti-oxidation, mitochondrial dynamics and mitophagy in a SIRT3-dependent manner. Furthermore, honokiol activated SIRT3 through the AMPK-PGC-$1{\alpha}$ signaling pathway. Moreover, honokiol treatment ameliorated IVDD in rats. Our study indicated that SIRT3 is involved in IVDD and showed the potential of the SIRT3 agonist honokiol for the treatment of IVDD.

Estimation of Head Loss Coefficients at Surcharged Square Manhole Using Numerical Model (수치모형을 이용한 과부하 사각형 맨홀에서의 손실계수 산정)

  • Kim, Jung-Soo;Lim, Ga-Hui;Rim, Chang-Soo;Yoon, Sei-Eui
    • Journal of the Korean Society of Hazard Mitigation
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    • v.11 no.3
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    • pp.143-150
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    • 2011
  • Energy loss at manholes, often exceeding friction loss of pipes under surcharged flow, is considered as one of the major causes of inundation in urban area. Therefore, it is important to analyze the head losses at manholes, especially in case of surcharged flow. The stream characteristics were analyzed and head loss coefficients were estimated by using the computational fluid dynamics(CFD) model, FLUENT 6.3, at surcharged square manhole in this study. The CFD model was carefully assessed by comparing simulated results with the experimental ones. The study results indicate that there was good agreement between simulation model and experiment. The CFD model was proved to be capable of estimating the head loss coefficients at surcharged manholes. The head loss coefficients with variation of the ratio of manhole width(B) to inflow pipe diameter(d) and variation of the drop height at surcharged square manhole with a straight-path through were calculated using FLUENT 6.3. As the ratio of B/d increases, head loss coefficient increases. The depth and head loss coefficient at manhole were gradually increased when the drop height was more than 5cm. Therefore, the CFD model(Fluent 6.3) might be used as a tool to simulate the water depth, energy losses, and velocity distribution at surcharged square manhole.

Effects of a Team Facilitation Program on Team Activities in Problem Based Learning (문제중심학습(PBL)에서 팀 활동을 촉진을 위한 퍼실리테이션 프로그램 적용에 대한 융합 연구)

  • Yang, Bok-Sun;Choi, Kyeong-Yoon;Sim, Jeoung-Ha
    • Journal of the Korea Convergence Society
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    • v.10 no.6
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    • pp.299-308
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    • 2019
  • This quasi-experimental study was conducted to develop and implement a team facilitation program as well as to evaluate the effects of the program on Problem Based Learning (PBL) and how these influence on team dynamics. Data were collected in a convenient sample of 126 nursing students (intervention group=69; control group=57). Data were analyzed using ${\chi}^2$ test, T-test, and ANCOVA. SPSS23 was used. The intervention group received the PBL team facilitation program, whereas the control group received a human interaction training. The intervention group than the control group demonstrated significantly higher scores in a team dynamic among team members(F=10.35,p<0.01), trust among team members(F=9.86,p<0.01), communication(F=5.69,p<0.05), learning behavior of a team(F=4.57,p<0.05), and individual capability evaluation(F=5.12,p<0.05). Team performance was not significantly different between groups. This study reveals that the team facilitation program is an effective strategy to maximize the effects of PBL. We propose the need for educational strategy to support team function.

Efficiency of Different Roof Vent Designs on Natural Ventilation of Single-Span Plastic Greenhouse (플라스틱 단동온실의 천창 종류에 따른 자연환기 효과)

  • Rasheed, Adnan;Lee, Jong Won;Kim, Hyeon Tae;Lee, Hyun Woo
    • Journal of Bio-Environment Control
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    • v.28 no.3
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    • pp.225-233
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    • 2019
  • In the summer season, natural ventilation is commonly used to reduce the inside air temperature of greenhouse when it rises above the optimal level. The greenhouse shape, vent design, and position play a critical role in the effectiveness of natural ventilation. In this study, computational fluid dynamics (CFD) was employed to investigate the effect of different roof vent designs along with side vents on the buoyancy-driven natural ventilation. The boussinesq hypothesis was used to simulate the buoyancy effect to the whole computational domain. RNG K-epsilon turbulence model was utilized, and a discrete originates (DO) radiation model was used with solar ray tracing to simulate the effect of solar radiation. The CFD model was validated using the experimentally obtained greenhouse internal temperature, and the experimental and computed results agreed well. Furthermore, this model was adopted to compare the internal greenhouse air temperature and ventilation rate for seven different roof vent designs. The results revealed that the inside-to-outside air temperature differences of the greenhouse varied from 3.2 to $9.6^{\circ}C$ depending on the different studied roof vent types. Moreover, the ventilation rate was within the range from 0.33 to $0.49min^{-1}$. Our findings show that the conical type roof ventilation has minimum inside-to-outside air temperature difference of $3.2^{\circ}C$ and a maximum ventilation rate of $0.49min^{-1}$.

A Study on the Thermal Flow Analysis for Heat Performance Improvement of a Wireless Power Charger (열 유동해석을 통한 무선충전기 발열 성능 향상에 관한 연구)

  • Kim, Pyeong-Jun;Park, Dong-Kyou
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.310-316
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    • 2019
  • In automotive application, customers are demanding high efficiency and various functions for convenience. The demand for these automotive applications is steadily increasing. In this study, it has been studied the analysis of heat flow to improve the PCB(printed circuit board) heating performance of WPC (wireless power charger) recently developed for convenience. The charging performance of the wireless charger has been reduced due to power dissipation and thermal resistance of PCB. Therefore, it has been proposed optimal PCB design, layout and position of electronic parts through the simulation of heat flow analysis and PCB design was analyzed and decided at each design stage. Then, the experimental test is performed to verify the consistency of the analysis results under actual environmental conditions. In this paper, The PCB modeling and heat flow simulation in transient response were performed using HyperLynx Thermal and FloTHERM. In addition, the measurement was performed using infrared thermal imaging camera and used to verify the analysis results. In the final comparison, the error between analysis and experiment was found to be less than 10 % and the heating performance of PCB was also improved.

Fates of water and salts in non-aqueous solvents for directional solvent extraction desalination: Effects of chemical structures of the solvents

  • Choi, Ohkyung;Kim, Minsup;Cho, Art E.;Choi, Young Chul;Kim, Gyu Dong;Kim, Dooil;Lee, Jae Woo
    • Membrane and Water Treatment
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    • v.10 no.3
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    • pp.207-212
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    • 2019
  • Non-aqueous solvents (NASs) are generally known to be barely miscible, and reactive with polar compounds, such as water. However, water can interact with some NASs, which can be used as a new means for water recovery from saline water. This study explored the fate of water and salt in NAS, when saline water is mixed with NAS. Three amine solvents were selected as NAS. They had the same molecular formula, but were differentiated by their molecular structures, as follows: 1) NAS 'A' having the hydrophilic group ($NH_2$) at the end of the straight carbon chain, 2) NAS 'B' with symmetrical structure and having the hydrophilic group (NH) at the middle of the straight carbon chain, 3) NAS 'C' having the hydrophilic group ($NH_2$) at the end of the straight carbon chain but possessing a hydrophobic ethyl branch in the middle of the structure. In batch experiments, 0.5 M NaCl water was blended with NASs, and then water and salt content in the NAS were individually measured. Water absorption efficiencies by NAS 'B' and 'C' were 3.8 and 10.7%, respectively. However, salt rejection efficiency was 98.9% and 58.2%, respectively. NAS 'A' exhibited a higher water absorption efficiency of 35.6%, despite a worse salt rejection efficiency of 24.7%. Molecular dynamic (MD) simulation showed the different interactions of water and salts with each NAS. NAS 'A' formed lattice structured clusters, with the hydrophilic group located outside, and captured a large numbers of water molecules, together with salt ions, inside the cluster pockets. NAS 'B' formed a planar-shaped cluster, where only some water molecules, but no salt ions, migrated to the NAS cluster. NAS 'C', with an ethyl group branch, formed a cluster shaped similarly to that of 'B'; however, the boundary surface of the cluster looked higher than that of 'C', due to the branch structure in solvent. The MD simulation was helpful for understanding the experimental results for water absorption and salt rejection, by demonstrating the various interactions between water molecules and the salts, with the different NAS types.

Development of Panel-Based Rapid Aerodynamic Analysis Method Considering Propeller Effect (프로펠러 효과를 반영 가능한 패널 기반 신속 공력 해석 기법 개발)

  • Tai, Myungsik;Lee, Yebin;Oh, Sejong;Shin, Jeongwoo;Lim, Joosup;Park, Donghun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.49 no.2
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    • pp.107-120
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    • 2021
  • Electric-powered distributed propulsion aircraft possess a complex wake flow and mutual interference with the airframe, due to the use of many propellers. Accordingly, in the early design stage, rapid aerodynamic and load analysis considering the effect of propellers for various configurations and flight conditions are required. In this study, an efficient panel-based aerodynamic analysis method that can take into account the propeller effects is developed and validated. The induced velocity field in the region of propeller wake is calculated based on Actuator Disk Theory (ADT) and is considered as the boundary condition at the vehicle's surface in the three-dimensional steady source-doublet panel method. Analyses are carried out by selecting an isolated propeller of the Korea Aerospace Research Institute (KARI)'s Quad Tilt Propeller (QTP) aircraft and the propeller-wing configuration of the former experimental study as benchmark problems. Through comparisons with the results of computational fluid dynamics (CFD) based on actuator methods, the wake velocity of propeller and the changes in the aerodynamic load distribution of the wing due to the propeller operation are validated. The method is applied to the analysis of the Optional Piloted Personal Aerial Vehicle (OPPAV) and QTP, and the practicality and validity of the method are confirmed through comparison and analysis of the computational time and results with CFD.

An Experimental Study on the Dynamic Increase Factor and Strain Rate Dependency of the Tensile Strength of Rock Materials (암석재료 인장강도의 동적 증가계수 및 변형률 속도 의존성에 대한 실험적 연구)

  • Oh, Se-Wook;Choi, Byung-Hee;Min, Gyeong-Jo;Jung, Yong-Bok;Cho, Sang-Ho
    • Explosives and Blasting
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    • v.39 no.1
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    • pp.10-21
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    • 2021
  • Brittle materials such as rocks and concretes exhibit large strain-rate dependency under dynamic loading conditions. This means that the mechanical properties of such materials can significantly be varied according to load velocity. Thus, the strain-rate dependency is recognized as one of the most important considerations in solving problems of blast engineering or rock dynamics. Unfortunately, however, studies for characterizing the dynamic properties of domestic rocks and other brittle materials are still insufficient in the country. In this study, dynamic tensile tests were conducted using the Hopkinson pressure bar apparatus to characterize the dynamic properties of Geochang granite and high-strength concrete specimens. The dynamic Brazilian disc test, which is suggested by ISRM, and the spalling method were applied. In general, the latter is believed to have some advantages in experiments under high-strain rate deformation. It was found from the tests that there were no significant difference between the dynamic tensile strengths obtained from the two different test methods for the two materials given. However, this was not the expected result before the tests. Actually, authors expected that there be some differences between them. Hence, it is thought that further investigations are needed to clarify this results.

Control of the flow past a sphere in a turbulent boundary layer using O-ring

  • Okbaz, Abdulkerim;Ozgoren, Muammer;Canpolat, Cetin;Sahin, Besir;Akilli, Huseyin
    • Wind and Structures
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    • v.35 no.1
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    • pp.1-20
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    • 2022
  • This research work presents an experimental study's outcomes to reveal the impact of an O-ring on the flow control over a sphere placed in a turbulent boundary layer. The investigation is performed quantitatively and qualitatively using particle image velocimetry (PIV) and dye visualization. The sphere model having a diamater of 42.5 mm is located in a turbulent boundary layer flow over a smooth plate for gap ratios of 0≤G/D≤1.5 at Reynolds number of 5 × 103. Flow characteristics, including patterns of instantaneous vorticity, streaklines, time-averaged streamlines, velocity vectors, velocity fluctuations, Reynolds stress correlations, and turbulence kinetic energy (), are compared and discussed for a naked sphere and spheres having O-rings. The boundary layer velocity gradient and proximity of the sphere to the flat plate profoundly influence the flow dynamics. At proximity ratios of G/D=0.1 and 0.25, a wall jet is formed between lower side of the sphere and flat plate, and velocity fluctuations increase in regions close to the wall. At G/D=0.25, the jet flow also induces local flow separations on the flat plate. At higher proximity ratios, the velocity gradient of the boundary layer causes asymmetries in the mean flow characteristics and turbulence values in the wake region. It is observed that the O-ring with various placement angles (𝜃) on the sphere has a considerable alteration in the flow structure and turbulence statistics on the wake. At lower placement angles, where the O-ring is closer to the forward stagnation point of the sphere, the flow control performance of the O-ring is limited; however, its impact on the flow separation becomes pronounced as it is moved away from the forward stagnation point. At G/D=1.50 for O-ring diameters of 4.7 (2 mm) and 7 (3 mm) percent of the sphere diameter, the -ring exhibits remarkable flow control at 𝜃=50° and 𝜃=55° before laminar flow separation occurrence on the sphere surface, respectively. This conclusion is yielded from narrowed wakes and reductions in turbulence statistics compared to the naked sphere model. The O-ring with a diameter of 3 mm and placement angle of 50° exhibits the most effective flow control. It decreases, in sequence, streamwise velocity fluctuations and length of wake recovery region by 45% and 40%, respectively, which can be evaluated as source of decrement in drag force.