• Title/Summary/Keyword: expected efficacy

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A Study on the College Student's Recognition and Consumption of Antioxidant in Seoul Area (대학생의 항산화에 대한 인식 및 항산화 식품 섭취 실태 -서울 지역을 중심으로-)

  • Lee, Young Soon;Bang, Hyeon Ho;Du, Xin Yi;Lee, Hye Won;Li, Feng Xiao;Jeon, Hyo Ju;Jun, Young Mi
    • Journal of the East Asian Society of Dietary Life
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    • v.22 no.6
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    • pp.758-771
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    • 2012
  • This research contains awareness of antioxidant and intakes of antioxidant foods for the present evaluate college students in Seoul, 375 patients were investigated. The subjects, the woman college student more than male's responded, showed a uniform distribution in the allowance, grade and the most type of residence is living apart from their family. All male and female college students recognize a lot about health, but male college students had higher than female students interested in the health, on the other hand, female college students had higher than male college students for the health efforts for the promotion of a healthy. Awareness about the oxide and active oxygen is moderate level, but knowledge about active oxygen is low level, they responded that active oxygen was caused when received stress or do strenuous exercise. General Health Functional Foods recognized that the usual intake, but intake of antioxidant was when the activity was caused by active oxygen. They recognized that the antioxidant effect is anti-aging and vitamin, wine and tea, were perceived as antioxidant foods, are popularly known. Usually, people was initially recognized through the internet in university or high school, they desire to obtain information was high but the effort to gain understanding and knowledge about antioxidant are relatively low. The result of comparing the difference of natural antioxidant foods and antioxidant healthy functional foods, recognizes of effects and absorption rate are similar, but recognizes that natural food intake is better recognition in the economics and health functional food is better recognition in the easy intake and nature foods was more preferred than functional foods because of nature friendly. Trying to intake of antioxidant foods is low, but people is expected anti-aging and fatigue recovery through the intake of antioxidant food. People think that intake is irrelevant to the season, but summer is higher than other seasons. Showed that efficacy perceptions about health supplements are higher, but efficacy perceptions about antioxidant health supplements when ingested are at a moderate level, which is lower, due to low antioxidant for understanding. Antioxidant functional health food intake will be affected the gifts or the people around them and purchase is also more influenced by surround people than themselves. So showed that most college students prefer natural antioxidant foods than antioxidant health supplements, in case of ingested antioxidant health supplements also showed that it was consumed by surround people than personal will.

Analysis of Convergent Influence of Self Efficacy, Job Characteristics and Occupational Stress on Job Satisfaction among Hospital Administrative Staff (병원행정직의 자기효능감, 직무특성 및 직무스트레스가 직무만족도에 미치는 융복합적 영향 분석)

  • Bae, Sang-Yun;Kim, Seung-Hee
    • Journal of Digital Convergence
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    • v.15 no.7
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    • pp.239-246
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    • 2017
  • We study convergent influence on Job Satisfaction(JS) and its association with Self Efficacy(SE), Job Characteristics(JC) and Occupational Stress(OS) among Hospital Administrative Staff(HAS). The survey was administered to 221 staff from 11 general hospitals located in Jeonbuk area from Nov. 1st, 2016 to Jan. 31st, 2017. The structured self-administered questionaries were used. JS was positively correlated with SE and three sub-domains of JC, and it was negatively correlated with seven sub-domains of OS. With the analysis of covariance structure, OS was more influential on JS than SE and JC. The study found the higher SE and JC, and the lower OC tend to increase JS. The results indicate that the efforts, to increase SE and JC, and to decrease OS, are required to increase the JS of HAS. The results are expected to be useful for organization personnel management to increase the JS of HAS. In the following study, the analysis about convergent additional factors of influence on JS will be needed.

A Study on the Evaluation Method of Soil Treatment Termiticide (흰개미 토양처리제 효과 평가 및 시험방안 연구)

  • Im, Ik Gyun;Jeong, Seon Hye;Chung, Yong Jae
    • Journal of Conservation Science
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    • v.35 no.2
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    • pp.177-186
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    • 2019
  • A Termiticide that is applied to the soil treatment method, one of the methods for preventing termites in Korea's wooden cultural properties, will be subjected to the leaching of the effective ingredient in treated soil by the moisture behavior of rain. As a result, termiticide is deteriorated and needs to be reprocessed, but the standards and evaluation methods are nonexistent in korea. Accordingly, a basic indoor evaluation measure was proposed for the evaluation of the effectiveness of the termiticide chamber and the calculation of the reprocessing period. First, avoidance and contact toxicity were assessed at two concentrations of the same termiticide as a method for assessing termiticide suitability. The evaluation of mortality revealed that the soil termiticide used in this experiment was non-repellent, and that death from contact was confirmed. Afterwards, artificial rainfall and soil penetration tests were conducted to determine efficacy of termiticide in soil and the approximate reprocessing period was calculated by comparing the weather data. Persistence evaluation revealed perforation by termites after continuous water exposure of more than about 160 to 170mm of water injection condition. Based on the results, compared with weather data for the last five years, the termiticide of concentration used in this experiment is expected to remain effective for about one year if treated after September. The purpose of this study was to provide basic data for the establishment of a manual for the selection of termiticide for soil treatment by calculating the efficacy for termite mortality and the duration of the leaching effectiveness by water behavior in soil.

Changes of Efficacy of Antioxidant, Antidyslipidemic, Antidiabetic and Microbiological Characteristics in Fermented and Salt-treated Fermented Codonopsis lanceolata (발효 더덕 및 소금 처리 발효 더덕의 미생물 특성과 항산화, 항비만, 항당뇨 효능 변화)

  • Seong, Eun-Hak;Lee, Myeong-Jong;Kim, Hojun;Shin, Na Rae
    • Journal of Korean Medicine for Obesity Research
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    • v.18 no.2
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    • pp.106-114
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    • 2018
  • Objectives: We investigated about the microbial properties and changes in the efficacy of the Codonopsis lanceolata (CL) by natural fermentation. Methods: CL was fermented for four weeks in a well-ventilated place with 2.5% salt. pH, total sugar, total polyphenol, and total flavonoid were measured to determine fermentation characteristics according to fermentation period and salt treatment. Polymerase chain reaction denaturing gradient gel electrophoresis and random amplification of polymorphic DNA-polymerase chain reaction were carried out for microbial analysis during fermentation. In addition, HepG2 cell was cultured to check the lipid accumulation through oil red O staining and the glucose uptake was analyzed by measuring the 2-NBDG at C2C12 cell. Results: The pH level and the total sugar decreased with the CL fermentation. Total polyphenol and flavonoid increased after CL fermentation. It was confirmed that Leuconostoc mesenteroides were maintained continuously during fermentation. In the salt treatment CL, there was a sharp increase in Rahnella aquatilis. Lactobacillus plantarum matrix was observed in fermented CL. In addition, Lactococcus lactis, Weissella koreensis, R. aquatilis, L. plantarum, Leu. mesenteroides have been added to the salt treatment. Glucose uptake were significantly increased after fermentation with salt for four weeks. Lipid accumulation in the HepG2 cells was observed that there was difference (P<0.01) between free fatty acid group (100%) and decreased 4 weeks after fermentation (90.38%) at $800{\mu}g/mL$. Conclusions: Total polyphenol and flavonoid were increased after CL fermentation. Especially, percentage of the glucose uptake and lipid accumulation inhibition increased in CL fermentation with salt. It is expected that fermentation of salt treated CL will be more effective in diabetes and fatty liver.

Cosmetic Application Using Skin Whitening and Anti-microbial effects of Ethyl Acetate and n-Butanol Fractions from Eruca sativa (Eruca sativa 에칠아세테이트와 부탄올 분획물의 미백 및 항균효과를 이용한 화장품 응용연구)

  • Park, Jihye;Lee, Kwang-ho;Kim, Bora
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.3
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    • pp.651-661
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    • 2021
  • Eruca sativa, called arugula, is a perennial plant in the Brassicaceae family, an edible plant commonly used in Italian cuisine. To study as a cosmetic material application E. sativa was extracted with 70% ethanol (ES). Then ES was fractionated using n-hexane, chloroform, ethyl acetate, n-butyl alcohol and water (EHex, EEA, ECHCl3, EBuOH and EDW). EEA showed mushroom tyrosinase inhibitory activity. ES, EEA and EBuOH showed inhibition of tyrosinase activity. As a result, ES is expected to have skin whitening efficacy. ES was applied to 0.05, 0.1% the toner and emulsion formulation to test the stability. The anti-microbial activity of eight bacteria and fungi including Staphylococcus aureus and Propionibacterium acnes which cause dermatitis and acne was evaluated. EEA showed effects in all of microorganisms. The toner and emulsion containing ES with 0.05, 0.1% were passed in the challenge test. At -20, 4, 25, 55 ℃ and daylight, there was no significant change on pH, viscosity for 4 months. However, emulsions had phase separation phenomenon at 55 ℃, so the base formulation needs improvement. In addition, through the skin penetration test, EEA penetrated 0.058% in 6 hr, predicting the clinical efficacy. This means that E. sativa can contribute whitening agent and the synergistic effect of preservatives.

A Study on Attitudes and Acceptance of Port Digital Transformation (항만 디지털 전환에 대한 수용태도와 수용성에 관한 연구)

  • Song, Hyeon-Deok;Chang, Myung-Hee
    • Journal of Korea Port Economic Association
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    • v.39 no.3
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    • pp.155-178
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    • 2023
  • The purpose of this study is to derive factors that affect the acceptance of digital transformation in ports and empirically analyze the impact of these factors on the acceptance of digital transformation through a survey of port workers. Additionally, we test whether acceptance attitude plays a mediating role in the relationship between these factors and digital transformation acceptance. The variables used in this study are as follows. First, knowledge, self-efficacy, and involvement were included as variables related to individual characteristics, relative advantages, complexity, observability were included as variables related to innovation characteristics, and government regulations and competitor pressure were included as variables relate to environmental characteristics, so that a total of eight latent variables were selected. The results of this study are summarized as follows. First, two variables among individual characteristics, self-efficacy and involvement, were able to confirm a positive(+) causal relationship with the attitude of accepting digital transformation, and knowledge initially expected a positive(+) causal relationship with the attitude of accepting digital transformation, but the result was a negative(-) causal relationship, so that the hypothesis was rejected. Second, among the characteristics of innovation, complexity has a negative(-) causal relationship with the attitude of accepting digital transformation, and relative advantages and technological innovation have a positive(+) causal relationship with the attitude of accepting digital transformation. Finally, among the environmental characteristics, government regulations and competitor pressure, confirmed a positive(+) causal relationship with the attitude of accepting digital transformation. In addition, it was found that the attitude of accepting digital transformation had a positive(+) causal relationship with personal acceptance and social acceptance of digital transformation.

Stabilization of Quercetin using Organo-hectorite and Its Application in Sunscreen Cosmetics (오가노 헥토라이트를 이용한 쿼세틴 안정화 및 자외선 차단 제품 응용에 관한 연구)

  • Sang Uk Kim;Ji Yeon Hong;Yong Woo Kim;In Ki Hong;Song Hua Xuan;Mid Eum Yun;Sung Ho Lee
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.50 no.1
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    • pp.1-10
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    • 2024
  • In this study, a quercetin benton gel (QUERPLEX) that stabilized quercetin was prepared using organo hectorite, and its efficacy was confirmed. In addition, a comparative study was conducted on the stability and effectiveness of applying this to sunscreen cosmetics. It was confirmed that QUERPLEX remained stable without showing crystal precipitation and growth for 4 weeks. As a result of measuring antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), it showed antioxidant activity depending on the concentration, and showed a radical elimination ability of 70% or more at a concentration of 2,500 ppm or more, confirming a significant effect. Anti-inflammatory activity experiments using RAW 264.7 cells confirmed that NO production decreased in a concentration-dependent manner by reducing NO production by 8% at 25 ㎍/mL, 23% at 50 ㎍/mL, and 84% at 100 ㎍/mL. As a result of confirming the stability of the formulation according to the method of quercetin in the sunscreen formulation, the stability of the formulation was improved when quercetin was added directly to the formulation. It also improved the UV protection index on in vitro and in vivo, which is expected to have the potential as a component that can have a new boosting effect on UV protection. These results suggest that organo hectorite is very effective as a quercetin carrier and that it can be applied in cosmetic formulations by not only expressing the efficacy of quercetin but also bringing about additional effects.

Study on Application of Skin Care Cosmetic and Stabilization of Idebenone by Forming Niosome Vesicle Technology

  • Kim, In-Young
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.2
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    • pp.592-599
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    • 2019
  • This study is to stabilize insoluble and unstable active ingredient which is Idebenone (INCI name: hydroxydecyl ubiquinone) in a multi-lamellar vesicle (MLV) and to stabilize it in the skin care cosmetics. Idebenone is good effective raw material in the treatment of Alzheimer's disease in the medical field and a powerful antioxidant in dermatology. It is well known as a substance that inhibits the formation of melanin and cleans the skin pigment. However, it did not dissolve in any solvent and it was difficult to apply in cosmetic applications. Niosome vesicle was able to develop a nano-particle by making a multi-layer of idebenone encapsulated with a nonionic surfactant, hydrogenated lecithin and glycine soja (soybean) sterols and passing it through a high pressure microfluidizer. Idebenone niosome vesicle (INV) has been developed to have the ability to dissolve transparently in water and to promote transdermal penetration. The appearance of the INV was a yellowish liquid having specific odor, and the particle size distribution of INV was about 10~80 nm. The pH was 5~8 (mean=6.8). This capsulation with idebenone was stored in a $45^{\circ}C$ incubator for 3 months and its stability was observed and quantitatively measured by HPLC. As a result, the stability of the sample encapsulated in the niosome vesicle (97.5%) was about 66.3% higher than that of the non-capsule sample of 32.5%. Idebenone 1% INV was used for the efficacy test and clinical trial evaluation as follows. The anti-oxidative activity of INV was 38.2%, which was superior to that of 12.8% tocopherol (control). The melanin-reducing effect of B16 melanoma cells was better than INV (17.4%) and Albutin (control) (9.6%). Pro-collagen synthesis rate was 128.2% for INV and 89.3% for tocopherol (control). The skin moisturizing effect was 15.5% better than the placebo sample. The elasticity effect was 9.7% better than the placebo sample. As an application field, INV containing 1% of idebenone is expected to be able to develop various functional cosmetic formulations such as skin toner, ampoule essence, cream, eye cream and sunblock cream. In addition, it is expected that this encapsulated material will be widely applicable to emulsifying agents for skin use in the pharmaceutical industry as well as the cosmetics industry.

A Study of Factors Affecting Use Intention of Untact Medical Diagnosis and Consultation Services (비대면 진료의 이용의도에 미치는 영향에 관한 연구)

  • Jin, Seok
    • The Journal of the Korea Contents Association
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    • v.20 no.12
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    • pp.180-197
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    • 2020
  • The purpose of this study is to explain intention to use untact medical diagnosis and consultation services. There is a need for untact medical diagnosis and consultation services in order to increase social interests and a global trend for public protection and convenience enhancement. We carry out the analysis of the survey data using Smart PLS 3.0 to test the hypotheses. According to the empirical analysis results, this study confirms that health consciousness have significant effects on the cost saving, quality of telemedicine service and self-efficacy have significant effects on the accessibility, compatibility. cost saving, quality of telemedicine service, accessibility and compatibility have significant effects on Perceived usefulness. Perceived usefulness have significant effects on use Intention of untact medical diagnosis and consultation services. This study has its meaning because it found out that it deals structurally and expansively with use intention through Expected Benefit and usefulness based on individual characteristics for untact medical diagnosis and consultation services. In addition, The results of this study suggest that if the related policies are institutionalized based on the Expected Benefits covered in this study, the perception of untact medical diagnosis and consultation services can be changed progressively.

Performance Comparison of Machine Learning based Prediction Models for University Students Dropout (머신러닝 기반 대학생 중도 탈락 예측 모델의 성능 비교)

  • Seok-Bong Jeong;Du-Yon Kim
    • Journal of the Korea Society for Simulation
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    • v.32 no.4
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    • pp.19-26
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    • 2023
  • The increase in the dropout rate of college students nationwide has a serious negative impact on universities and society as well as individual students. In order to proactive identify students at risk of dropout, this study built a decision tree, random forest, logistic regression, and deep learning-based dropout prediction model using academic data that can be easily obtained from each university's academic management system. Their performances were subsequently analyzed and compared. The analysis revealed that while the logistic regression-based prediction model exhibited the highest recall rate, its f-1 value and ROC-AUC (Receiver Operating Characteristic - Area Under the Curve) value were comparatively lower. On the other hand, the random forest-based prediction model demonstrated superior performance across all other metrics except recall value. In addition, in order to assess model performance over distinct prediction periods, we divided these periods into short-term (within one semester), medium-term (within two semesters), and long-term (within three semesters). The results underscored that the long-term prediction yielded the highest predictive efficacy. Through this study, each university is expected to be able to identify students who are expected to be dropped out early, reduce the dropout rate through intensive management, and further contribute to the stabilization of university finances.