• Title/Summary/Keyword: exact sequence

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Medication Errors in Chemotherapy Preparation and Administration: a Survey Conducted among Oncology Nurses in Turkey

  • Ulas, Arife;Silay, Kamile;Akinci, Sema;Dede, Didem Sener;Akinci, Muhammed Bulent;Sendur, Mehmet Ali Nahit;Cubukcu, Erdem;Coskun, Hasan Senol;Degirmenci, Mustafa;Utkan, Gungor;Ozdemir, Nuriye;Isikdogan, Abdurrahman;Buyukcelik, Abdullah;Inanc, Mevlude;Bilici, Ahmet;Odabasi, Hatice;Cihan, Sener;Avci, Nilufer;Yalcin, Bulent
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.1699-1705
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    • 2015
  • Background: Medication errors in oncology may cause severe clinical problems due to low therapeutic indices and high toxicity of chemotherapeutic agents. We aimed to investigate unintentional medication errors and underlying factors during chemotherapy preparation and administration based on a systematic survey conducted to reflect oncology nurses experience. Materials and Methods: This study was conducted in 18 adult chemotherapy units with volunteer participation of 206 nurses. A survey developed by primary investigators and medication errors (MAEs) defined preventable errors during prescription of medication, ordering, preparation or administration. The survey consisted of 4 parts: demographic features of nurses; workload of chemotherapy units; errors and their estimated monthly number during chemotherapy preparation and administration; and evaluation of the possible factors responsible from ME. The survey was conducted by face to face interview and data analyses were performed with descriptive statistics. Chi-square or Fisher exact tests were used for a comparative analysis of categorical data. Results: Some 83.4% of the 210 nurses reported one or more than one error during chemotherapy preparation and administration. Prescribing or ordering wrong doses by physicians (65.7%) and noncompliance with administration sequences during chemotherapy administration (50.5%) were the most common errors. The most common estimated average monthly error was not following the administration sequence of the chemotherapeutic agents (4.1 times/month, range 1-20). The most important underlying reasons for medication errors were heavy workload (49.7%) and insufficient number of staff (36.5%). Conclusions: Our findings suggest that the probability of medication error is very high during chemotherapy preparation and administration, the most common involving prescribing and ordering errors. Further studies must address the strategies to minimize medication error in chemotherapy receiving patients, determine sufficient protective measures and establishing multistep control mechanisms.

Classification of Passing Vessels Around the Ieodo Ocean Research Station Using Automatic Identification System (AIS): November 21-30, 2013 (선박자동식별장치(AIS)를 이용한 이어도 종합해양과학기지 주변 통항 선박의 분류: 2013년 11월 21일~30일)

  • Hong, Dan-Bee;Yang, Chan-Su
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.17 no.4
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    • pp.297-305
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    • 2014
  • In this study, we installed the Automatic Identification System (AIS) receiver on the Ieodo Ocean Research Station (IORS) from November 21 to 30, 2013 in order to monitor marine traffic and fishery activity in the jurisdictional sea area. The collected AIS raw data consist of static data report (MMSI, IMO NO., Call Sign, Ship Name, etc.) and position information report (position, speed, course, etc.), and the developed program was applied to classify ships according to ship flag and type information. The nationalities are released from the first three-digit numbers (MID) of MMSI, but in general most of small ships do not send an exact ship flag through Class B type AIS, a simplified and low-power equipment. From AIS data with flag information, ships under the flag of China had the highest frequency and the second was Korean flag, while in ship type cargo and fishing vessels were dominant in sequence. As for the ships without flag information, we compared the tracks with others in order to estimate ship flags. It can be said that fleets of ships with Chinese frequently appear sail together for fisheries over the waters, because the unknown ships followed a similar moving pattern with Chinese fishing vessels.

Characterization of Noble AmpC-Type $\beta$-Lactamases Among Clinical Isolates Using New Expression/Secretion Vector (발현ㆍ분비 벡터 및 임상 균주가 생성하는 신규 AmpC-type $\beta$-lactamase의 특성)

  • 정하일;성광훈;이정훈;장선주;이상희
    • Korean Journal of Microbiology
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    • v.40 no.2
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    • pp.104-110
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    • 2004
  • To determine evolution and genotype of new chromosomal AmpC $\beta$-lactamases among clinical isolates of Enterobacter species, we performed antibiotic susceptibility testing, pI determination, sequencing, and phy-logenetic analysis using developed expression/secretion vector. Six isolates have shown to produce AmpC $\beta$-lactamases. Six genes of AmpC $\beta$-lactamases that are responsible for the resistance to cephamycins (cefoxitin and cefotetan), amoxicillin, cephalothin, and amoxicillin-clavulanic acid were cloned and characterized in pMSG12119. Insert fragment containing the ampC genes was sequenced and found to have an open reading frame coding for 381-amino-acid $\beta$-lactamase. The nucleotide sequence of four ampC genes ($bla_EcloK992004.l$, $bla_EcloK995120.1$, $bla_EcloK99230$, and $bla_EareK9911729$) shared considerable homology with that of chromosomal ampC gene ($bla_EcloMHN1$) of E. cloacae MHN1 (more than 99.6% identity). The sequences of two ampC genes ($bla_EcloK9973$ and $bla_EcloK9914325$) showed close similarity to the chromosomal ampC gene ($bla_EcloQ908R$) of E. clo-acae 908R (99.7% identity). The results from phylogenetic analysis suggested that six ampC genes could be originated from $bla_EcloMHN1$ / or $bla_EcloQ908R$ / MIC patterns and exact pI values of six transformants indicated that the developed expression/secretion vector (pMSG1219) was suitable for the characterization of foreign genes in E. coli strain.

Occurrence of Rust on Peucedanum japonicum Caused by Puccinia jogashimensis in Korea (Puccinia jogashimensis에 의한 갯기름나물 녹병)

  • Ko, Sug-Ju;Kim, Hyo-Jeong;Myung, Inn-Shik;Uhm, Mi-Jeong;Choi, In-Young
    • Research in Plant Disease
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    • v.21 no.4
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    • pp.337-340
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    • 2015
  • During July to November 2014, severe rust infection was consistently found on Peucedanum japonicum growing farm in Yeosu, Korea. The rust was observed mainly on lower leaf surfaces. Symptoms of typical plants included yellow-orange rust pustules were observed on the petiole and leaf surface with small yellowish to chlorotic lesions on the upper surface. No symptom was observed on flowers. Uredinia were occurred amphigenous on leaf surface, and occasionally caulicolous, scattered or loosely aggregate, rounded to oblong, 0.4 to 4 mm in diameter, covered by epidermis, then naked, surrounded by ruptured epidermis, pulverulent, and brown. Urediniospores were ovate-ellipsoid, ellipsoid or subglobose, light brown, 20 to $45{\times}15$ to $35{\mu}m$, walls 2 to $4{\mu}m$ thick. The resulting sequences were deposited in GenBank with accession No. KT778808, KT778809, and KT778810, respectively. Since this was the first accession of 28S sequence Puccinia jogashimensis, there was no exact match in GenBank nucleotide database. On the basis of the morphological characteristics and phylogenetic analyses of 28S rDNA, the fungus was identified as P. jogashimensis. To our knowledge, this is the first confirmed report on the occurrence of P. jogashimensis on P. japonicum in Korea.

Meaning of Waiting Experience and Principles of Service Design (서비스 대기시간에서 사용자 경험의 의미와 서비스 디자인 원칙)

  • Kwon, Ohkyun;Kim, HyunYoung;Kim, Bomyeong;Lee, Jiin;Ha, Taehoon;Lee, Inseong;Kim, Jinwoo
    • The Journal of the Korea Contents Association
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    • v.17 no.1
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    • pp.270-286
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    • 2017
  • Managing waiting experience is critical for providing service because waiting is an inevitable experience. We explored the factors which influence the waiting experience of the customers and the experience they face, in order to find out the meaning of waiting experience of the customer. As a result, we investigated a holistic sequence divided into four stages. When the customers wait for the service, perceived time would be increased by Zeigarnik effect. How long the customers feel when waiting is largely affected by a gap between waiting time and the perceived time, rather than the perceived time itself. Furthermore, the customers showed a tendency to have hard time immersing in the media due to considering others. Additionally, we could find that waiting time after giving an order is relatively more important than the waiting time before the order. Based on the results, the service provider should convey a feeling of completion by fitting the end point of the media to the point when the customer receives the service. In addition, high predictability needs to be offered for the customers in order to predict the exact waiting time. Finally, the customers should feel as if they take the initiative during waiting time.

Development of Intelligent Multiple Camera System for High-Speed Impact Experiment (고속충돌 시험용 지능형 다중 카메라 시스템 개발)

  • Chung, Dong Teak;Park, Chi Young;Jin, Doo Han;Kim, Tae Yeon;Lee, Joo Yeon;Rhee, Ihnseok
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.37 no.9
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    • pp.1093-1098
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    • 2013
  • A single-crystal sapphire is used as a transparent bulletproof window material; however, few studies have investigated the dynamic behavior and fracture properties under high-speed impact. High-speed and high-resolution sequential images are required to study the interaction of the bullet with the brittle ceramic materials. In this study, a device is developed to capture the sequence of high-speed impact/penetration phenomena. This system consists of a speed measurement device, a microprocessor-based camera controller, and multiple CCD cameras. By using a linear array sensor, the speed-measuring device can measure a small (diameter: up to 1 2 mm) and fast (speed: up to Mach 3) bullet. Once a bullet is launched, it passes through the speed measurement device where its time and speed is recorded, and then, the camera controller computes the exact time of arrival to the target during flight. Then, it sends the trigger signal to the cameras and flashes with a specific delay to capture the impact images sequentially. It is almost impossible to capture high-speed images without the estimation of the time of arrival. We were able to capture high-speed images using the new system with precise accuracy.

Aeroelastic Tailoring of a Forward-Swept Wing Using One-dimensional Beam Analysis (1차원 보 해석을 활용한 전진익 항공기의 복합적층 날개 공력탄성학적 테일러링)

  • Choi, JaeWon;Lim, ByeongUk;Lee, SiHun;Shin, SangJoon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.48 no.8
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    • pp.555-563
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    • 2020
  • Foward-swept wings are known to possess superior aerodynamic performance compared to the conventional straight wings. However major concerns regarding forward-swept wings include divergence at lower airspeeds which require careful consideration at the design stage. As an endeavor to overcome such drawbacks, aeroelastic tailoring is attempted. In order to find an optimal ply sequence, recursive aeroelastic analyses is conducted and one-dimensional beam analysis coupled with simple aerodynamics is used for the improved computational efficiency and modelling convenience. The analysis used in this paper, DYMORE and analytic formula, both use one-dimensional beam model for the structure. Cross-sectional analysis for multi-cell NACA0015 airfoil section is conducted using VABS and oblique function is used for the sweep angle. Throughout the present aeroelastic tailoring, the maximum divergence speed of 290.2m/s is achieved which is increased by approximately 43% than that for the conventional ply configuration.

Real-Time Object Tracking Algorithm based on Pattern Classification in Surveillance Networks (서베일런스 네트워크에서 패턴인식 기반의 실시간 객체 추적 알고리즘)

  • Kang, Sung-Kwan;Chun, Sang-Hun
    • Journal of Digital Convergence
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    • v.14 no.2
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    • pp.183-190
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    • 2016
  • This paper proposes algorithm to reduce the computing time in a neural network that reduces transmission of data for tracking mobile objects in surveillance networks in terms of detection and communication load. Object Detection can be defined as follows : Given image sequence, which can forom a digitalized image, the goal of object detection is to determine whether or not there is any object in the image, and if present, returns its location, direction, size, and so on. But object in an given image is considerably difficult because location, size, light conditions, obstacle and so on change the overall appearance of objects, thereby making it difficult to detect them rapidly and exactly. Therefore, this paper proposes fast and exact object detection which overcomes some restrictions by using neural network. Proposed system can be object detection irrelevant to obstacle, background and pose rapidly. And neural network calculation time is decreased by reducing input vector size of neural network. Principle Component Analysis can reduce the dimension of data. In the video input in real time from a CCTV was experimented and in case of color segment, the result shows different success rate depending on camera settings. Experimental results show proposed method attains 30% higher recognition performance than the conventional method.

EARLY DEVELOPMENT OF THE TOOTH IN THE STAGED HUMAN EMBRYOS AND FETUSES (한국인 배자 및 태아에서 유치 발생의 조직학적 변화)

  • Lim, Hee-Sik;Park, Hyoung-Woo;Oh, Hyeon-Joo;Kim, Hee-Jin;Choi, Byung-Jai
    • Journal of the korean academy of Pediatric Dentistry
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    • v.25 no.2
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    • pp.383-399
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    • 1998
  • Tooth development is usually described in four stages such as bud stage, cap stage, bell stage and crown stage. Exact time of appearance of tooth primordia is different among reports, and up to now there is no timetable regarding initial tooth development. To understand the congenital malformations and other disorders of the orofacial region, there is a need to establish a standard timetable on early tooth development. Till now, studies on the tooth development were mainly on later fetuses, and only few reports on early stage. Also, there were no reports on the time when bud stage turns to cap stage, and cap stage to bell stage. In this study, external morphology of face and the early development of the tooth, and transition of bud stage to cap stage, cap stage to bell stage were studied using 27 staged human embryos and 9 serially sectioned human fetuses. The results are as follows: 1. Mandibular region was formed by union of both mandibular arch at stage 15, and maxillary region by union of maxillary arch, medial nasal prominence, and intermaxillary segment at stage 19. 2. Ectodermal thickening which represents the primordia of tooth appeared in mandibular region at stage 13, and maxillary region at stage 15. 3. Bud stage began from mandibular primary central incisor at stage 17, and maxillary primary central incisor at stage 18. And the sequence of appearance was in the mandibular primary lateral incisor at stage 19, maxillary primary lateral incisor at stage 20, mandibular primary canine at stage 22, maxillary primary canine and primary first molar at stage 23, madibular primary first molar and maxillary primary second molar at 9th week, and mandibular primary second molar at 10th week of development. 4. Cap stage began from the primary anterior teeth at 9th week, and primary second molar still had the characteristics of cap stage at 12th week of development. 5. Transition to bell stage started from the primary anterior teeth at 12th week, and primary second molar started at 16th week of development. 6. Trnasition to crown stage started from primary anterior teeth at 16th week, and primary second molar at 26th week of development.

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Enhanced Grid-Based Trajectory Cloaking Method for Efficiency Search and User Information Protection in Location-Based Services (위치기반 서비스에서 효율적 검색과 사용자 정보보호를 위한 향상된 그리드 기반 궤적 클로킹 기법)

  • Youn, Ji-Hye;Song, Doo-Hee;Cai, Tian-Yuan;Park, Kwang-Jin
    • KIPS Transactions on Computer and Communication Systems
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    • v.7 no.8
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    • pp.195-202
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    • 2018
  • With the development of location-based applications such as smart phones and GPS navigation, active research is being conducted to protect location and trajectory privacy. To receive location-related services, users must disclose their exact location to the server. However, disclosure of users' location exposes not only their locations but also their trajectory to the server, which can lead to concerns of privacy violation. Furthermore, users request from the server not only location information but also multimedia information (photographs, reviews, etc. of the location), and this increases the processing cost of the server and the information to be received by the user. To solve these problems, this study proposes the EGTC (Enhanced Grid-based Trajectory Cloaking) technique. As with the existing GTC (Grid-based Trajectory Cloaking) technique, EGTC method divides the user trajectory into grids at the user privacy level (UPL) and creates a cloaking region in which a random query sequence is determined. In the next step, the necessary information is received as index by considering the sub-grid cell corresponding to the path through which the user wishes to move as c(x,y). The proposed method ensures the trajectory privacy as with the existing GTC method while reducing the amount of information the user must listen to. The excellence of the proposed method has been proven through experimental results.