• Title/Summary/Keyword: exact methods

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A Study on the Statistical Probability Instruction through Computer Simulation (컴퓨터 시뮬레이션을 통한 통계적 확률 지도에 대한 연구)

  • Shin Bo-Mi;Lee Kyung-Hwa
    • Journal of Educational Research in Mathematics
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    • v.16 no.2
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    • pp.139-156
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    • 2006
  • The concept of probability in current school mathematics has been dealt with in the classic viewpoint (mathematical probability) and part of the frequency viewpoint and axiomatic viewpoint have been introduced. However, since the exact understanding of the probability concepts is not possible only with the classic viewpoint, we need to research further on methods to complement classic viewpoint and emphasize various aspects of probability concepts (Lee, Kyung Hwa, 1996). Therefore, this study is to find out optimal computer simulation plans in teaching statistical probability. For the purpose, it examines how the nature of mathematical knowledge may be changed when statistical probability is taught with a use of computer simulation based on the Theory of Didactical Situation presented by Brousseau(1997). Next, it identifies how probability curriculum should be reconstituted for introducing statistical probability through computer simulation. Finally, it develops specific teaching materials that introduce statistical probability using computer simulation based on the results obtained.

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Genome Wide Expression Analysis of the Effect of Woowhangchongshim-won on Rat Brain Injury

  • Kim, Bu-Yeo;Lim, Se-Hyun;Kim, Hyun-Young;Kim, Young-Kyun;Lim, Chi-Yeon;Cho, Su-In
    • The Journal of Internal Korean Medicine
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    • v.30 no.3
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    • pp.594-603
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    • 2009
  • Objectives : ICH breaks down blood vessels within the brain parenchyma, which finally leads to neuronal loss, drugs to treat ICH have not yet been established. In this experiment, we measured the effect of Woowhangchongshim-won (WWCSW) on intracerebral hemorrhage (ICH) in rat using microarray technology. Methods : We measured the effect of WWCSW on ICH in rat using microarray technology. ICH was induced by injection of collagenase type IV, and total RNA was isolated. Image files of microarray were measured using a ScanArray scanner, and the criteria of the threshold for up- and down-regulation was 2 fold. Hierarchical clustering was implemented using CLUSTER and TREEVIEW program, and for Ontology analysis. GOSTAT program was applied in which p-value was calculated by Chi square or Fisher's exact test based on the total array element. Results : WWCSW-treatment restored the gene expression altered by ICH-induction in brain to the levels of 76.0% and 70.1% for up- and down-regulated genes, respectively. Conclusion : Co-regulated genes by ICH model of rat could be used as molecular targets for therapeutic effects of drug including WWCSW. That is, the presence of co-regulated genes may represent the importance of these genes in ICH in the brain and the change of expression level of these co-regulated genes would also indicate the functional change of brain tissue.

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Clinical Study on 1 Case of Soyangyin Patient Diagnosed as Crohn's Disease (크론씨병으로 진단된 소양인 환자 치험 1 례)

  • Lee, Seung-Hyun;Park, Darn-Seo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.5
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    • pp.1346-1351
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    • 2007
  • Crohn' disease is an auto-immune disease characterized by intermittent chronic diarrhea, high fever, weight loss, abdominal spastic pain or abdominal discomfort which is followed by granulomatous necrosis and cicatrical inflammation. It is also called segmental enteritis or granulomatous enteritis. In western medicine the exact cause is undefined, however it is presumed as an immunological unbalance in alimentary tract commoonly occured in ileum portion of small intestitine or ascending colon and therefore immuno suppressive agents(usually steroids) and anti-inflammatory drugs are prescribed. In case of emergency such as ileus, perforation of intestinal wall surgical methods are considered. In oriental medicine this falls under the category of diarrhea(泄瀉), dysentery(痢疾), splenic diarrhea(脾泄). As to the pathological mechanism the abnormal ascending and descending circulation of stomach and splenic energy(脾不升淸, 胃不下降) the hepatic stagnation(肝鬱氣滯) and dysfunction of small intestine in expelling urine and feces(小陽淸獨不利) all together causes such condition. Main treatments are inducing diuresis(利小便), warming kindey to reinforce yang(溫賢助陽), nourishing the middle energy to invigorate spleen(補中健脾), elimination of the dampness by cooling(淸熱燥濕). In this case the patient was diagnosed as soyangyin(少陽人) constitution and herb medicine soyangyin Hyongbangjihwan-tang(少陽人 荊防地黃湯), Sa-am acupuncture Sojangjeonggyeok(小腸政格) was applied. There was an significant improve in chief complaints and general conditions.

A Basic Study on Fall Patterns for Fracture Prevention System (골절방지 시스템을 위한 낙상 패턴에 관한 기초 연구)

  • Kim S.H.;Kim K.;Jung S.H.;Kim G.B.;Kwon T.K.;Hong C.U.;Kim N.G.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1925-1928
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    • 2005
  • In recent years, the importance of the characterization of fall for a fracture prevention system keeps increasing since fracture from a fall can lead to serious health problems. Fall is one of the major sources which increase morbidity in elderly people. In terms of the cost and the influence to the quality of life, the most serious injury with hip fractures is caused by falls. The traditional methods in characterizing fall patterns have been mainly by the epidemiological surveys. With surveys, the exact data of fall patterns can not been acquired. In this paper, we measured and analyzed with the parameters related to fall pattern such as velocities and accelerations during the motion of falls using 3D motion capture program. We acquired the parameters of the fall pattern of intentional and unexpected fall. The result showed that the variation of velocity and acceleration during fall was very important in characterizing fall pattern, which of vital importance for the development of a fracture prevention system and for the safety of the elderly

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Trichomonas vaginalis Adhesion Protein 33: A Useful Target for Diagnosis of T. vaginalis

  • Joo Kyung Bok;Rho Pyong-Ui;Park Seung Kyu;Kim Jae Won;Lee Kyu Jae;Ryang Yong Suk
    • Biomedical Science Letters
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    • v.11 no.1
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    • pp.15-22
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    • 2005
  • Trichomoniasis is a sexually transmitted disease induced by Trichomonas vaginalis, a parasitic protozoan. The symptoms of trichomoniasis are rarely appeared that the infections are distributed worldwide from underdeveloped to developed countries. The diagnosis of trichomoniasis is mainly taken by wet smear following microscopic examination, of which the diagnostic accuracies are poor and varies with the clinicians' experiences. Therefore, more exact and convenient diagnostic methods for T. vaginalis are required. Here, we cloned and expressed recombinant T. vaginalis adhesion protein 33 (rTvAP33) using an E. coli expression system. rTvAP33 was then immunized to rabbit and BALB/c mice for the production of anti-rTvAP33 antibodies. Sandwich ELISA using these antibodies detected T. vaginalis cultured in TYM broth supplemented with ferrous ions. Vagina-parasitizing microorganisms showed low cross-reactivities in this system. These results suggest that Tv AP33 is a good diagnostic target for the detection of TvAP33-expressing T. vaginalis.

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The Difference of Syndrome Differentiation Patterns between Premenopausal and Climacteric Obese Korean Women (폐경전 및 갱년기 과체중 한국 성인 여성의 변증 지표 차이에 대한 연구)

  • Chung, Won-Suk;Hwang, Mi-Ja;Lee, A-Ra;Moon, Jin-Seok;Choi, Sun-Mi;Song, Mi-Yeon
    • Journal of Korean Medicine for Obesity Research
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    • v.8 no.2
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    • pp.37-47
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    • 2008
  • Objectives The aim of the study was to investigate the difference between pattern identification of premenopausal(n=39) and climacteric(n=40) korean obese and overweight women using Syndrome Differentiation Questionaire. Methods 39 premenopausal obese women(BMI${\geq}25kg/m^2$) and 40 climacteric overweight and obese women(BMI${\geq}23kg/m^2$) were recruited from October 2007 to March 2008 in Seoul, Korea. Subjects who had other disease were rejected. Basic anthropometry and body composition were measured. Every subjects were given and filled out the Syndrome Differentiation Questionaire, and we analyzed that using Fisher's exact test. Results 1. Premenopausal women showed high frequency of food accumulation pattern(43.6%), but in climacteric women, liver qi depression pattern was frequent(57.5%, p=0.021). 2. In weighted Syndrome Differentiation Questionaire score, Premenopausal women showed high frequency of food accumulation pattern(43.6%), but in climacteric women, liver qi depression pattern was frequent(47.5%, p=0.004). 3. There were no correlation between anthropometry and scores of the each patterns. Conclusions In this study, we can find out that the dietary factors play major roles in obesity of premenopausal women and emotional factors in obese climacteric women in the view of oriental pattern identification diagnosis. But it seemed that there lacked of consideration that reflected the degree of obesity in this Syndrome Differentiation Questionaire.

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The Proper Volume and Distribution of Cement Augmentation on Percutaneous Vertebroplasty

  • Kim, Dong-Joon;Kim, Tae-Wan;Park, Kwan-Ho;Chi, Moon-Pyo;Kim, Jae-O
    • Journal of Korean Neurosurgical Society
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    • v.48 no.2
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    • pp.125-128
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    • 2010
  • Objective : The purpose of this study was to determine the optimal volume of injected cement and its distribution when used to treat vertebral compression fractures, and to identify factors related to subsequent vertebral fractures. Methods : A retrospective analysis of newly developing vertebral fractures after percutaneous vertebroplasty was done. The inclusion criteria were that the fracture was a single first onset fracture with exclusion of pathologic fractures. Forty-three patients were included in the study with a minimum follow up period of six months. Patients were dichotomized for the analysis by volume of cement, initial vertebral height loss, bone marrow density, and endplate-to-endplate cement augmentation. Results : None of the four study variables was found to be significantly associated with the occurrence of a subsequent vertebral compression fracture. In particular, and injected cement volume of more or less that 3.5 cc was not associated with occurrence (p = 0.2523). No relation was observed between initial vertebral height loss and bone marrow density (p = 0.1652, 0.2064). Furthermore, endplate-to-endplate cement augmentation was also not found to be significantly associated with a subsequent fracture (p = 0.2860) by Fisher's exact test. Conclusion : Neither volume of cement, initial vertebral height loss, bone marrow density, or endplate-to-endplate cement augmentation was found to be significantly related to the occurrence of a subsequent vertebral compression fracture. Our findings suggest that as much cement as possible without causing leakage should be used.

Fall Simulation and Impact Absorption system for Development of Fracture Prevention System (골절 방지 시스템의 개발을 위한 낙상 시뮬레이션과 충격 흡수 시스템에 관한 연구)

  • Kim, S.H.;Kim, D.W.;Kim, N.G.
    • Journal of Biomedical Engineering Research
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    • v.31 no.6
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    • pp.438-448
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    • 2010
  • The social activities of the elderly have been increasing as our society progresses toward an aging society. As their activities are increased, the occurrence of falls that could lead to fractures are increased. Falls are serious health hazards to the elderly and we need more thorough understanding of falls including the progress of falls and the impact area in various fall directions. Many of the traditional methods of falls research dealt with voluntary falls by younger subject since older subject can easily get fracture from voluntary falls. So, it has been difficult to get exact data about falls of the elderly. Here, we tried to capture the characteristics of the movements of major joints using three dimensional motion capture system during falls experiments using a moving mattress that can safely induce unexpected falls. Healthy younger subjects participated in the actual falls experiment and the moving mattress was actuated by a pneumatic system. The kinematic parameters such as velocities of major segments were imported to a computer simulation environment and falls to hard surfaces were simulated in a computational environment using a realistic human model of aged persons. The simulation was able to give approximations to contact forces which can occur during actual falls. And we designed impact absorption system to reduce the impact during falls. We can adapt this system to fracture prevention system that we are going to study.

The Meaning of Practice in Theory (이론(理論, Theoria)에 있어서의 실기의 의미)

  • Kang, Tai-Sung
    • The Journal of Art Theory & Practice
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    • no.1
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    • pp.7-22
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    • 2003
  • What is 'Art Theory'? In the western sense, the term poses a vague ambiguity, and in the eastern, it is rather an abstract and metaphysical concept. As for etymology, theory is derived from theoria and theoria from theoros. It refers to an act of viewing or seeing, of course not in a metaphysical sense. Plato understood it as 'eide'. During the time of Plotinus, theoria encompassed gazing at every possible reality, and this gazing, that is theoria, is closely related to reality as aunit that theoriacan perceive. However, we tend to distinguish, as other scientists of dualism have done, studio art from theory since a pre-modern approach to art has been particularly tuned to studio practice, set apart from theory. Therefore, in studio classes, students are expected to learn the subject based on the foundational curriculum methods such as medium, genre, technique:, rather than bringing out their own interpretations and discussing theories. As a result, students have become artists, who are not able to understand their own art. Art professors who conduct class in studio are required to proceed with specific 'theories' as well as 'intellectual reflections'. In this respect, this thesis presents poiesis and an idea of 'acting out'. Although art history and aesthetic theory tend to view art as a finished product, actual art-making and related theories should not only be acknowledged as 'completion' (finition) but also be accompanied by theoretic interpretations of the act itself and process. Accordingly, it is to accept and appreciate art as finished result in view of current theory and aesthetics thus boils down to aisthesis. Likewise, poietics starts from a point where an artist is related to studio and examines the 'work process' that extends as far as to the exact end of work. Through the study of such relationship, it is possible that theory understands 'studio' and 'process', and an artist can grant an independent meaning to studio where s/he pours her/his heart out creating a work of art. Theory is a study on artistic discovery thus should be equipped with functions that can accommodate fortuity, imitation, thinking, culture, and surrounding.

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A Study of Approximation Method of Spatial Objects (공간 객체의 근사화 방법 연구)

  • Kim, Yong-Hyeon;Lee, Hyeong-Su;Lee, Seong-Su;Kim, Eung-Mo
    • The Transactions of the Korea Information Processing Society
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    • v.3 no.7
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    • pp.1753-1762
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    • 1996
  • Since the number of spatial objects go easily into millions, they are stored on a secondary storage. In order to speed up accessing the geometric objects, we investigate spatial database system. The spatial objects are organized and accessed by spatial access methods(SAMs). But, SAMs are not able to organize polygons directly The most popular approach for handing polygon in SAMs is to use MBR apporximaotion as a geometric key. MBR provides a fast but inaccurate answers to approximation-based query processing. The performance of approximation-based spatial query processing depends on which type of approximation is chosen for the spatial objects. A suitable approximation is crucial for reducing the size of the candidate set. The better the approxmation quality, the fewer accesses to the exact object are necessary. In this paper, I proposed a new multicontainer approximation named Slice decomposition. The performance of proposed method is compared with other method.

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