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Seroprevalence and risk factors of Lyme disease among Korean deer farmers (대한민국 사슴농가 종사자의 라임병 혈청유병률 및 위험요인)

  • Acharya, Dilaram;Cho, Jae-Hak;Yoo, Seok-Ju;Park, Ji-Hyuk
    • Journal of agricultural medicine and community health
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    • v.44 no.2
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    • pp.82-89
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    • 2019
  • This study was undertaken to determine the seroprevalence and risk factors associated with contracting Lyme disease (LD) among Korean deer farmers. This cross-sectional study devised questionnaire that addressed farm activities, was devised and the blood samples of 516 Korean deer farmers were tested. LD seroprevalence was determined by Western blot test. Fisher's exact test, the chi-squared test, and the chi-squared test for trend analysis were performed to assess the risk associated with LD. Of total 516 study participants recruited, only 12 (2.3%) were seropositive for LD. The result of the study revealed that only deer farmers raising Elk (Cervus Canadensis) were found to be at significantly higher risk of contracting LD than other deer farmers (p=0.033). In addition, a male sex, an age of < 40 years, and those that had raised deer for < 19 years had higher rates of LD infection than their counterparts. Similarly, those that managed livestock sheds, fed deer, processed industry and prepared compost had higher rates of LD infection. In terms of protective factors, those who did not use protective measures such as wear glasses and masks, or protective gloves and aprons, and those that did not disinfect work instruments and did not shower after work had higher rates of LD than those that used protective measures. In conclusion, preventive health strategies should take into account the profiles of deer farmers at greater risk based on considerations of personal, type of work, and the use of personal protective measures.

A Case Study of Sea Bottom Detection Within the Expected Range and Swell Effect Correction for the Noisy High-resolution Air-gun Seismic Data Acquired off Yeosu (잡음이 포함된 여수근해 고해상 에어건 탄성파 탐사자료에 대한 예상 범위에서의 해저면 선정 및 너울영향 보정 사례)

  • Lee, Ho-Young
    • Geophysics and Geophysical Exploration
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    • v.22 no.3
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    • pp.116-131
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    • 2019
  • In order to obtain high-quality high-resolution marine seismic data, the survey needs to be carried out at very low-sea condition. However, the survey is often performed with a slight wave, which degrades the quality of data. In this case, it is possible to improve the quality of seismic data by detecting the exact location of the sea bottom signal and eliminating the influence of waves or swells automatically during data processing. However, if noise is included or the sea bottom signal is weakened due to sea waves, sea bottom detection errors are likely to occur. In this study, we applied a method reducing such errors by estimating the sea bottom location, setting a narrow detection range and detecting the sea bottom location within this range. The expected location of the sea bottom was calculated using previously detected sea bottom locations for each channel of multi-channel data. The expected location calculated in each channel is also compared and verified with expected locations of other channels in a shot gather. As a result of applying this method to the noisy 8-channel high-resolution air-gun seismic data acquired off Yeosu, the errors in selecting the strong noise before sea bottom or the strong subsurface reflected signal after the sea bottom signal are remarkably reduced and it is possible to produce the high-quality seismic section with the correction of ~ 2.5 m swell effect.

First Report of a Bracken Blight Disease Caused by Didymella sp. (Didymella sp.에 의한 고사리 신규 마름병 발생 보고)

  • Lee, Jung Eun;Kim, Ki Beom;Park, Ju Eun;Kim, Da-Woon;Shin, Yoo-Kyoung;Yun, Sung-Hwan;Chung, Young-Ryun
    • Research in Plant Disease
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    • v.25 no.3
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    • pp.143-148
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    • 2019
  • An outbreak of new disease with leaf and stem blight symptom occurred at bracken-growing fields in Namhae-gun, Gyeongsangnam-do, Korea during the last 4 years. This new disease caused significant yield losses on bracken production in this area. We have collected diseased leaves and stems showing the blight symptom in May, July, and October 2018 to investigate causal pathogens. A total of 92 fungal isolates were obtained from the diseased samples and their pathogenicity was tested on healthy bracken leaves. From the total isolates, 22 isolates were able to produce the leaf blight symptom similar to the original one found in the fields. To identify two fungal pathogens which showed higher virulence levels compared to other pathogenic isolates, we constructed phylogenetic trees using the nucleotide sequences of genes for ribosomal RNA, RNA polymerase beta subunit, beta tubulin, and internal transcribed region. Most phylogenetic trees constructed indicate that both isolates, which are identical to each other, reside in a clade of the genus Didymella and possibly similar to D. rumicicola or D. acetosellae. Nevertheless, the exact identification of these pathogens at the species level needs further investigations. This is the first report of a blight disease on bracken by Didymella sp.

H-NS binding on dicA promoter DNA inhibits dicA gene expression (dicA promoter DNA에 붙는 H-NS 단백질에 의한 dicA 유전자의 발현 조절)

  • Yun, Sang Hoon;Lee, Yonho;Lim, Heon M.
    • Korean Journal of Microbiology
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    • v.55 no.3
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    • pp.191-198
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    • 2019
  • H-NS binds to promoter DNA and works as a general transcription silencer. DicA protein, by binding to the promoter DNA of dicA, activates dicA expression and at the same time inhibits expression of dicF and dicB, thus, exerting cell division control in Escherichia coli. H-NS complexed with a nucleoid protein Cnu was known to be involved in dicA expression. However, the exact nature of H-NS binding to dicA promoter DNA and the consequences of H-NS binding in expression of dicA is not clear. In this study, we explored the DNA binding activity of H-NS on the promoter DNA of dicA and found that H-NS binding occurs exclusively to the dicA promoter DNA. We never observed, however, H-NS binding at the vicinity of the dicA promoter. Temperature dependent oligomerization of H-NS was observed during DNA binding and the Cnu protein enhances the oligomerization process of H-NS binding. In vivo measurement of dicA expression in an hns deleted strain showed that dicA expression increased. These results demonstrated that H-NS binds specifically to dicA promoter DNA and functions as a transcription silencer.

Analysis of Sensors' Behavior and Its Utility for Shallow Landslide Early Warning through Model Slope Collapse Experiment (붕괴모의실험을 통한 산사태 조기경보용 계측센서의 반응성 분석 및 활용성 고찰)

  • Kang, Minjeng;Seo, Junpyo;Kim, Dongyeob;Lee, Changwoo;Woo, Choongshik
    • Journal of Korean Society of Forest Science
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    • v.108 no.2
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    • pp.208-215
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    • 2019
  • The goal of this study was to analyze the reactivity of a volumetric water content sensor (soil moisture sensor) and tensiometer and to review their use in the early detection of a shallow landslide. We attempted to demonstrate shallow and rapid slope collapses using three different soil ratios under artificial rainfall at 120 mm/h. Our results showed that the measured value of the volumetric water-content sensor converged to 30~37%, and that of the tensiometer reached -3~-5 kPa immediately before the collapse of the soil under all three conditions. Based on these results, we discussed a temporal range for early warnings of landslides using measurements of the volumetric water content sensors installed at the bottom of the soil slope, but could not generalize and clarify the exact timing for these early warnings. Further experiments under various conditions are needed to determine how to use both sensors for the early detection of shallow landslides.

In-Plane Extensional Vibration Analysis of Asymmetric Curved Beams with Linearly Varying Cross-Section Using DQM (미분구적법(DQM)을 이용한 단면적이 선형적으로 변하는 비대칭 곡선보의 내평면 신장 진동해석)

  • Kang, Ki-Jun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.5
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    • pp.612-620
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    • 2019
  • The increasing use of curved beams in buildings, vehicles, ships, and aircraft has results in considerable effort being directed toward developing an accurate method for analyzing the dynamic behavior of such structures. The stability behavior of elastic curved beams has been the subject of a large number of investigations. Solutions of the relevant differential equations have traditionally been obtained by the standard finite difference. These techniques require a great deal of computer time as the number of discrete nodes becomes relatively large under conditions of complex geometry and loading. One of the efficient procedures for the solution of partial differential equations is the method of differential quadrature. The differential quadrature method(DQM) has been applied to a large number of cases to overcome the difficulties of the complex algorithms of programming for the computer, as well as excessive use of storage due to conditions of complex geometry and loading. In this study, the in-plane extensional vibration for asymmetric curved beams with linearly varying cross-section is analyzed using the DQM. Fundamental frequency parameters are calculated for the member with various parameter ratios, boundary conditions, and opening angles. The results are compared with the result by other methods for cases in which they are available. According to the analysis of the solutions, the DQM, used only a limited number of grid points, gives results which agree very well with the exact ones.

The study on structural vulnerability analysis of small fixed wing UAV with hard landing (동체 착륙 방식의 소형 고정익 무인항공기 구조 취약점 분석)

  • Jeong, Seong-rok;Kang, Ju-hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.20-25
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    • 2019
  • In this paper, the structural weakness analysis and quality improvement of small fixed wing UAV of the hard landing type were studied. Unlike conventional aircraft, small UAV does not use runways because of its small size. Instead, small UAV use hand launch takeoff and hard landings. This type has many operational advantages because it can take off and land in a narrow space. But, the hard landing has a strong impact on the structure of the UAV and can cause serious damage. In order to analyze the exact cause of this phenomenon, the structural analysis was carried out using the 3D structural analysis program (ABAQUS) to identify the location of the fracture. And to improve the accuracy of the structural analysis, properties of the material were obtained through specimen test. As a result of the analysis, structural weaknesses were identified and improved. Thus, the validity of the study was verified by demonstrating the quality of enhanced structure through a real impact test at a higher level of 1.5 times the maximum impact during operation.

Quantitative Feasibility Evaluation of 11C-Methionine Positron Emission Tomography Images in Gamma Knife Radiosurgery : Phantom-Based Study and Clinical Application

  • Lim, Sa-Hoe;Jung, Tae-Young;Jung, Shin;Kim, In-Young;Moon, Kyung-Sub;Kwon, Seong-Young;Jang, Woo-Youl
    • Journal of Korean Neurosurgical Society
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    • v.62 no.4
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    • pp.476-486
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    • 2019
  • Objective : The functional information of $^{11}C$-methionine positron emission tomography (MET-PET) images can be applied for Gamma knife radiosurgery (GKR) and its image quality may affect defining the tumor. This study conducted the phantom-based evaluation for geometric accuracy and functional characteristic of diagnostic MET-PET image co-registered with stereotactic image in Leksell $GammaPlan^{(R)}$ (LGP) and also investigated clinical application of these images in metastatic brain tumors. Methods : Two types of cylindrical acrylic phantoms fabricated in-house were used for this study : the phantom with an array-shaped axial rod insert and the phantom with different sized tube indicators. The phantoms were mounted on the stereotactic frame and scanned using computed tomography (CT), magnetic resonance imaging (MRI), and PET system. Three-dimensional coordinate values on co-registered MET-PET images were compared with those on stereotactic CT image in LGP. MET uptake values of different sized indicators inside phantom were evaluated. We also evaluated the CT and MRI co-registered stereotactic MET-PET images with MR-enhancing volume and PET-metabolic tumor volume (MTV) in 14 metastatic brain tumors. Results : Imaging distortion of MET-PET was maintained stable at less than approximately 3% on mean value. There was no statistical difference in the geometric accuracy according to co-registered reference stereotactic images. In functional characteristic study for MET-PET image, the indicator on the lateral side of the phantom exhibited higher uptake than that on the medial side. This effect decreased as the size of the object increased. In 14 metastatic tumors, the median matching percentage between MR-enhancing volume and PET-MTV was 36.8% on PET/MR fusion images and 39.9% on PET/CT fusion images. Conclusion : The geometric accuracy of the diagnostic MET-PET co-registered with stereotactic MR in LGP is acceptable on phantom-based study. However, the MET-PET images could the limitations in providing exact stereotactic information in clinical study.

Factors Influencing Prognosis of Traumatized Tooth in Primary Tooth Intrusion (유치 함입 시 외상 치아의 예후에 영향을 미치는 요인)

  • Chae, Yongkwon;Han, Yoonkyung;Nam, Okhyung;Kim, Misun;Lee, Hyoseol;Kim, Kwangchul;Choi, Sungchul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.1
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    • pp.29-37
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    • 2019
  • The purpose of this study was to investigate the characteristics of intrusion in primary dentition and to evaluate factors influencing complications of primary and permanent dentition during long-term follow-up period. 61 patients (84 teeth) were selected in this study. Medical records of 61 patients were reviewed and age, gender, cause of injury, site of injury, severity of traumatic injury, other injuries associated with trauma, treatment method, and complications of primary and permanent dentition were examined. Collected data were statistically evaluated using Chi-square test and Fisher's exact test. Intrusion in primary anterior teeth was predominant in boys over girls and fall was the most common cause of trauma. It was most common at home and occurred most in the primary maxillary central incisors. Severity had an effect on the incidence of sequelae in permanent successors (p = 0.014). The incidence of complications was significantly lower in patients with soft tissue injuries than in patients with other periodontal injuries (p = 0.000).

The Effect of Zippy's Friends program Based on Stress-Coping Model on Early -Child in Convergence Era (융합시대 학령초기 아동대상 스트레스-대처 모델 기반 Zippy's Friends 프로그램의 효과)

  • Kim, Minyi;Ko, Haneul;Kim, Soojin;Kim, Boyoung
    • Journal of the Korea Convergence Society
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    • v.10 no.5
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    • pp.359-367
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    • 2019
  • This study was done to examine the effect of 'Zippy's friends' program based on stress coping model for early child. A nonequivalent control group was designed to conduct a pre-post test for this study. The participants for this study were 148 first grade elementary school students in G city(experimental group=72, control group=76). The experimental group received 'Zippy's friends program for 24 weeks (6 module, 24 hours). The control group did not receive any treatment. From April to December 2017 data were collected using self-report structured questionnaires, and were analyzed using the ${\chi}^2$-test, t-test, and ANCOVA with SPSS/WIN 20.0 Program. After the treatment, significant differences were found between the experimental group and control groups in terms of stress coping ability( F=22.77, p<.001),but not in level of emotional intelligence (t=-.37, p=.715). Results of this study indicate that Zippy's program can be used in school based practice as an effective mental health intervention for early child.