• Title/Summary/Keyword: evidence base

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Kinetics and hydrolysis mechanism of insecticide O,O-diethyl-O-(1-phenyl-3-trifluoromethylpyrazol-5-yl)phosphorothioate (Flupyrazofos) (살충제 O,O-diethyl-O-(1-phenyl-3-trifluoromethylpyrazol-5-yl)-phosphorothioate(Flupyrazofos)의 가수분해 반응 메커니즘)

  • Sung, Nack-Do
    • The Korean Journal of Pesticide Science
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    • v.6 no.3
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    • pp.218-223
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    • 2002
  • The rate of hydrolysis of insecticide, O,O-diethyl-O-(1-phenyl-3-trifluoromethylpyrazol-5-yl)phosphorothioate (Flupyrazofos) have been investigated in 25% (v/v) aqueous dioxane (${\mu}=0.1M$) at $45^{\circ}C$. The hydrolysis mechanism of flupyrazofos proceeds through the specific acid ($A_{AC}2$) catalysis below pH 4.0, specific base ($B_{AC}2$) catalysis above pH 11.0 and general acid & base ($B_{AC}2$) catalysis between pH 5.0 and pH 10.0 via trigonal-bipyramidal ($d^2sp^3$) intermediate as evidence by solvent effect ($|m|{\ll}|{\ell}|$), rate equation ($kt=ko+k_H+ [H_3O^+]+k_{OH}[OH^-]$) and product analysis. The half-life ($T\frac{1}{2}$) of hydrolytic degradation in neutral media at $45^{\circ}C$ was ca. 3 months.

Studies on Korean Aconitum Species(I) -An Alkaloid of Aconitum sibiricum and the Comparison of Toxicities among Related Aconitum Species- (한국산(韓國産) 부자류(附子類) 생약(生藥)에 대한 연구(硏究)(I) -노랑투구꽃의 성분(成分) 연구(硏究) 및 관련된 부자류(附子類)의 독성(毒性) 비교(比較)-)

  • Chung, Bo-Sup;Kim, Sin-Keun;Lee, Hyung-Kyu;Kim, Seung-Han
    • Korean Journal of Pharmacognosy
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    • v.15 no.2
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    • pp.108-113
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    • 1984
  • The structure of tuguaconitine, MP $196{\sim}198^{\circ}C$, a new diterpene alkaloid isolated from the roots of Aconitum sibiricum P., was studied. Its empirical formula is $C_{23}H_{35}NO_7$ and spectroscopic evidence shows that the base contains three methoxyl, three hydroxyl and one N-ethyl groups. The acute toxicities of most of Aconitum species were strong and the acute toxicity of the alkaloid fraction of A. sibiricum was decreased by Glycyrrhizae, black bean or Zingiberis extract.

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Dehydrohalogenation Reactions Induced by Sodamide Containing Complex Bases (I). Mechanistic Studies on Dehydrohalogenation from trans-1,2-Dihalocyclohexanes (소다아미드를 포함하는 복합염기에 의한 탈할로겐화수소반응 (제1보). 트란스-1,2-디할로시클로헥산의 탈할로겐화수소 반응의 메카니즘 연구)

  • Jong Gun Lee;Kyung-Tae Kang;Euk-Suk Lee
    • Journal of the Korean Chemical Society
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    • v.28 no.1
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    • pp.20-25
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    • 1984
  • Sodamide-containing complex base induced dehydrohalogenations from trans-1,2-dihalocyclohexanes were investigated. Isomerization, deuterium isotope effect along with element effect and others provided strong evidence in favor of E2 reaction mechanism.

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Coronary Artery Bypass Grafti ng without Extracorporeal Ci rculation One Case Report (체외순환을 사용하지 않은 관상동맥우회술-1례보고-)

  • 임창영;이헌재
    • Journal of Chest Surgery
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    • v.30 no.3
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    • pp.326-329
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    • 1997
  • Coronary artery bypass grafting(CABG) without cardiopulmonary bypass(CPB) is now an accepted technique of myocardial revascularization in selective cases of coronary arterial occlusive disease. The lesion was total(100%) occlusion of proximal right coronary artery(RCA) without any evidence of dis,Base in the rest of coronary arteries. Percutaneous transluminal angioplasty(PTCA) was tried but unsuccessful. We herein report a case of successful CABG to right coronary artery without CPB on a patient with complete occlusion of RCA and symptomatic wit minimal activity.

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A Level Evaluation Model for Data Governance (데이터 거버넌스 수준평가 모델 개발의 제안)

  • Jang, Kyoung-Ae;Kim, Woo-Je
    • Journal of the Korean Operations Research and Management Science Society
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    • v.42 no.1
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    • pp.65-77
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    • 2017
  • The purpose of this paper is to develop a model of level evaluation for data governance that can diagnose and verify level of insufficient part of operating data governance. We expanded the previous study related on attribute indices of data governance and developed a level model of evaluation and items. The model of level evaluation for data governance is the level of evaluation and has items of 400 components. We used previous studies and expert opinion analysis such as the Delphi technique, KJ method in this paper. This study contributes to literature by developing a level evaluation model for data governance at the early phase. This paper will be used for the base line data in objective evidence of performance in the companies and agencies of operating data governance.

Urgent Intracranial Carotid Artery Decompression after Penetrating Head Injury

  • Kim, Seong Joon;Park, Ik Seong
    • Journal of Korean Neurosurgical Society
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    • v.53 no.3
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    • pp.180-182
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    • 2013
  • We describe a case of intracranial carotid artery occlusion due to penetrating craniofacial injury by high velocity foreign body that was relieved by decompressive surgery. A 46-year-old man presented with a penetrating wound to his face. A piece of an electric angular grinder disc became lodged in the anterior skull base. Computed tomography revealed that the disc had penetrated the unilateral paraclinoid and suprasellar areas without flow of the intracranial carotid artery on the lesion side. The cavernous sinus was also compromised. Removal of the anterior clinoid process reopened the carotid blood flow, and the injection of glue into the cavernous sinus restored complete hemostasis during extraction of the fragment from the face. Digital subtraction angiography revealed complete recanalization of the carotid artery without any evidence of dissection. Accurate diagnosis regarding the extent of the compromised structures and urgent decompressive surgery with adequate hemostasis minimized the severity of penetrating damage in our patient.

Capital Inflow Shocks and House Prices: Aggregate and Regional Evidence from Korea

  • Tillmann, Peter
    • East Asian Economic Review
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    • v.17 no.2
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    • pp.129-159
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    • 2013
  • Over the course of the recent global financial crisis, emerging economies experienced massive swings in capital inflows. In this paper, we estimate a VAR model to assess the impact of capital inflow shocks, which are identified using a set of sign restrictions, on house prices in Korea. We base the analysis on three alternative measures of capital inflows: net total inflows, net portfolio inflows and gross total inflows. The results suggest that capital inflow shocks have a significantly positive and persistent effect on real house prices. Although shocks to capital inflows are found to be substantially more important for Korean asset markets than for other OECD countries, their overall explanatory power is modest. Using regional house price data we also show that capital inflow shocks have an asymmetric effect on property markets across the seven largest Korean cities and across different parts of Seoul.

Success Factors of Knowledge Acquisition: The Absorptive Capacity Perspective on Adopters of ERP Packages (외부지식 획득성과의 영향 요인에 관한 연구: ERP 패키지 도입업체의 흡수역량 관점)

  • Suh, Hyun-Ju;Kim, Hyo-Gun
    • Asia pacific journal of information systems
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    • v.12 no.4
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    • pp.139-172
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    • 2002
  • Comtemporary firms need capability of acquiring external knowledge and internalizing it to cope with environmental fluctuation. The paper analyzes the impact of absorptive capacity, an ability to recognize and utilize external knowledge, on knowledge acquisition of the firm, and examines the role of trust in the knowledge acquisition process. Data were collected from 84 domestic companies that had adopted ERP packages. The results indicate that prior experiences of knowledge acquisition, communication mechanism, and conflict resolution mechanism affect knowledge acquisition positively. Among those independent variables, communication mechanism and conflict resolution mechanism significantly and positively related with trust. Trust is, in turn, positively associated with knowledge acquisition. Meanwhile, previous knowledge base and prior relationship with the knowledge provider do not affect knowledge acquisition. Further, the results provide evidence that trust plays a mediating role between other absorptive capacity factors and knowledge acquisition.

Exchange Rate Volatility: Empirical Evidence from Somalia in 2010

  • Mohamud, Isse Abdikadir
    • Journal of Distribution Science
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    • v.12 no.3
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    • pp.99-103
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    • 2014
  • Purpose - The objective of this study was to examine the volatility of the exchange rate of the Somali shilling (SoSh) during 2010, especially the exchange rate between the Somali shilling and US dollar. Research design, data, and methodology - The study employed aquantitative research design; the data was analyzed using contents analysis for the data pertaining to the exchange rate between the US dollar and Somali Shilling in 2010. Results - The main findings were that the exchange rate was very volatile during 2010 because of three sources: (1) Imbalance of demand and supply in the money market, (2) People adopting the US dollar as the medium of exchange forgoods and services, thereby reducing the circulation of the SoSh, and (3) Lack of a strong central bank. Conclusions - The study suggested three possible remedies: the establishment of an effective central bank that matches the demand and supply of the currencies, adoption of the Somali shilling as the official currency base for the prices of commodities, and minimizing the imports into the country and maximizing its exports, to support the strengthening of the Somali shilling.

Development of Web-based Diagnosis Expert System of Traditional Oriental Medicine (인터넷 기반 한의진단전문가 시스템(KHU-PIPE) 개발)

  • Choi Seung Hoon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.3
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    • pp.528-531
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    • 2002
  • In Traditional Oriental Medicine, there has been a growing needs for computerized diagnosis expert system, which can implement pre-diagnosis and correct the errors of practitioners. Therefore, we developed the expert system (KHU-PIPE : Kyung Hee University - Pattern Identification and Prescription Expert) for diagnosis and treatment. It has three characteristics as following. First. this system has the knowledge base which modified the standardized data designed by Chinese government during 1980s. Second, it provides the objective and standardized diagnosis as the results of pattern identification and their appropriate prescriptions for treatment. Third, it is applied to both LAN system and internet. Furthermore, it can be used as an educational methods for the practices of pattern identification and prescription, and provide the objective criteria for clinical studies and promote the Traditional Oriental Medicine as an evidence-based medicine.