• Title/Summary/Keyword: evaluation rule

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Two Cases of Metastatic Cancer Presenting as A Cervical Cyst (경부 낭종의 형태로 발현한 전이암 2례)

  • Son Young-Ik;Baek Chung-Hwan;Ha Byung-Suk;Chang Byung-Chan
    • Korean Journal of Head & Neck Oncology
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    • v.13 no.2
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    • pp.260-264
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    • 1997
  • Metastatic cancer presenting as a cervical cyst is uncommon, and often misdiagnosed as branchial cleft cyst. Authors experienced two cases which presented clinically with features of branchial cleft cyst, but were subsequently found to be metastatic cancer. Radiologic examination and fine needle aspiration biopsy proved to be non-diagnostic, and pathologic findings after surgical excision showed metastatic cancer. Further evaluation and examination were made to find out the primary focus, which revealed tonsillar squamous cell cancer and thyroid papillary cancer in each case. When cervical cysts are noted in aged patients, it is mandatory to rule out metastatic cancer until it is proven otherwise. Surgical excision and pathologic diagnosis should be always accompanied to make correct diagnosis and further treatment.

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A Study on the Safety-related Criteria for the Interior Space Planning, Facilities and Fire-fighting Equipment in Child Care Centers (보육시설의 실내공간계획 및 설비와 소방설비의 안전성 관련 기준에 대한 연구)

  • Rhee, Jisook
    • Journal of Families and Better Life
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    • v.31 no.6
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    • pp.39-51
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    • 2013
  • Because of the increasing demand for day care centers, The Korean government has enforced childcare accreditation. The government has created the evaluation certification system for child care facilities. But the system includes variable items, and the physical rules are not sufficient for ensuring security and quality amenities. So this study, through literature search, examined the rules of Child Care Centers in the U.S. and compared them with those in Korea focusing on the provision of security and amenities. The standards found in 4 U.S. states were investigated, and the results are as follows. The rule pertaining to the size of indoor activity spaces in C.C.C. allows the spaces to be smaller in Korea than in the U.S. There is no specific criterion for infants and toddlers in our standard. When comparing the standards of Korea with those of the United States, Korea's standards do not state specific rules about child care facilities such as indoor furniture, finishes and space planning. Additionally, the binding force ensuring compliance with the standards of physical facilities is weak. Thus, the ratings of child care standards for the physical environment should be presented in detail. And if a center does not comply with the criteria, stronger penalties will have to be imposed.

Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach

  • Sood, Damini;Kumar, Neeraj;Singh, Aarushi;Sakharkar, Meena Kishore;Tomar, Vartika;Chandra, Ramesh
    • Genomics & Informatics
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    • v.16 no.3
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    • pp.44-51
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    • 2018
  • Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary medicine. Herein, the antibacterial and pharmacological properties of four fluoroquinolones: lomefloxacin, norfloxacin, ciprofloxacin, and ofloxacin have been studied. The objective of this study was to analyze the antibacterial characteristics of the different fluoroquinolones. Also, the pharmacological properties of the compounds including the Lipinski rule of five, absorption, distribution, metabolism, and excretion, LD50, drug likeliness, and toxicity were evaluated. We found that among all four FQ molecules, ofloxacin showed the highest antibacterial activity through in silico assays with a strong interaction (-38.52 kJ/mol) with the antibacterial target protein (topoisomerase-II DNA gyrase enzyme). The pharmacological and pharmacokinetic analysis also showed that the compounds ciprofloxacin, ofloxacin, lomefloxacin and norfloxacin have good pharmacological properties. Notably, ofloxacin was found to possess an IGC50 (concentration needed to inhibit 50% growth) value of $0.286{\mu}g/L$ against the Tetrahymena pyriformis protozoa. It also tested negative for the Ames toxicity test, showing its non-carcinogenic character.

Evaluation of Liquefaction Potentional on Saturated Sand Layers in Korea (on the Development of Constitutive Relationships) (우리나라 포화사질지반의 액상화 포텐셜 평가 (구함관계 개발을 중심으로))

  • 도덕현;장병욱
    • Geotechnical Engineering
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    • v.6 no.3
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    • pp.41-52
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    • 1990
  • To investigate the liquefaction potential of sands, a series of untrained cyclic triaxial compression tests is carried out on the samples of Ottawa, Joomoonjin, Hn river and Hongseung sands. The constitutive equations of sands are derived to explain the mechanical behavior of sands under cyclic stresses, and are applicable to liquefaction analysis. The following results are obtainded in this study. 1. Sands with the lower confining pressure or relative density are to be easily liquefied, and when the amplitude of cyclic stress are large, liquefaction takes places over only a few cycles. 2. Stress ratio, porewater pressure ratio and cyclic shear strains are to be good criteria to evaluate liquefaction potential of sands. 3. Hongseung sands which contains some silty clay shows higher dynamic properties than other sands. 4. The dynamic behaviors of undisturbed Hongseung sand are about same as those of dense sands. It is noted that undisturbed Hongseung sand shows higher liquefaction potential than the samples made by pluviation under same relative density, 5. The constitutive equations of soils under cyclic loads are developed based on the theory of elasto-plasticity, logarithmic stress-strain rela'tionship, non-associated flow rule and the concept of the boundary surface. The derived equations is applicable to predict the behavior of sands under cyclic loads and liquefaction potential with a higher accuracy. 6. Based on results of the study it may be concluded that cracks of the foundations and dislocation of the structures at Hongseung earthquakes(Oct. 7, 1978, Richter scald 5.2) are not brought by the liquefaction process.

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Development of the Fuzzy Expert System for the Reinforcement of Tunels during Construction (터널 시공 중 보강공법 선전용 퍼지 전문가 시스템 개발)

  • 김창용;박치현;배규진;홍성완;오명렬
    • Journal of the Korean Geotechnical Society
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    • v.16 no.6
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    • pp.127-139
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    • 2000
  • In the study, an expert system was developed to predict the safety of tunnel and select proper tunnel reinforcement system using fuzzy quantification theory and fuzzy inference rule based on tunnel information database, For this development, many tunnelling sites were investigated and the applied countermeasures were studied after building tunnel database. There will be benefit for the deciding tunnel reinforcement method in the case of poor ground condition. The expert system developed in the study has two main parts, pre-module and post-module. Pre-module is used to decide input items of tunnel information based on the tunnel face mapping information which can be easily obtained in in-situ site. Then, using fuzzy quantification theory II, fuzzy membership function is composed and tunnel safety level is inferred through this membership function. Post-module is used to infer the applicability of each reinforcement methods according to the face level. The result of the predicted reinforcement system level was similar to measured ones. In-situ data were obtained in three tunnel sites including subway tunnel under Han River. Therefore, this system will be helpful to make the mose of in-situ data available and suggest proper applicability of tunnel reinforcement system to development more resonable tunnel support method without dependance of some experienced experts opinions.

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A Study on the Damage Safety Assessment in Ship Design Stage (선박설계단계에서 손상안전성 평가에 관한 연구)

  • Lee, Dong-Kon;Choi, Jin;Park, Beom-Jin;Kang, Hee-Jin;Lim, Seok-Nam
    • Journal of the Society of Naval Architects of Korea
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    • v.46 no.3
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    • pp.343-350
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    • 2009
  • Recently ship safety regulations are being reinforced to improve maritime safety and to prevent maritime pollution by International Maritime Organization. It means that the regulation is becoming more proactive rather than reactive. In the mean time, design philosophy is also moving from rule based design to performance and simulation based design. In this paper, a study on practical application of the damage safety assessment system is carried out. The damage stability and the survivability of a cargo ship that was designed based on current regulation is investigated using performance based design tools in order to improve the safety of the design and verify the performance of the developed damage safety assessment system. To do this, damage scenarios is established and the characteristics and geometry the cargo ship is modeled. A new design alternative is proposed with small change in the internal arrangement based on safety evaluation results of the current design.

Online Estimation of Rotational Inertia of an Excavator Based on Recursive Least Squares with Multiple Forgetting

  • Oh, Kwangseok;Yi, Kyong Su;Seo, Jaho;Kim, Yongrae;Lee, Geunho
    • Journal of Drive and Control
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    • v.14 no.3
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    • pp.40-49
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    • 2017
  • This study presents an online estimation of an excavator's rotational inertia by using recursive least square with forgetting. It is difficult to measure rotational inertia in real systems. Against this background, online estimation of rotational inertia is essential for improving safety and automation of construction equipment such as excavators because changes in inertial parameter impact dynamic characteristics. Regarding an excavator, rotational inertia for swing motion may change significantly according to working posture and digging conditions. Hence, rotational inertia estimation by predicting swing motion is critical for enhancing working safety and automation. Swing velocity and damping coefficient were used for rotational inertia estimation in this study. Updating rules are proposed for enhancing convergence performance by using the damping coefficient and forgetting factors. The proposed estimation algorithm uses three forgetting factors to estimate time-varying rotational inertia, damping coefficient, and torque with different variation rates. Rotational inertia in a typical working scenario was considered for reasonable performance evaluation. Three simulations were conducted by considering several digging conditions. Presented estimation results reveal the proposed estimation scheme is effective for estimating varying rotational inertia of the excavator.

A Study on the Estimation Model of Liquid Evaporation Rate for Classification of Flammable Liquid Explosion Hazardous Area (인화성액체의 폭발위험장소 설정을 위한 증발율 추정 모델 연구)

  • Jung, Yong Jae;Lee, Chang Jun
    • Journal of the Korean Society of Safety
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    • v.33 no.4
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    • pp.21-29
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    • 2018
  • In many companies handling flammable liquids, explosion-proof electrical equipment have been installed according to the Korean Industrial Standards (KS C IEC 60079-10-1). In these standards, hazardous area for explosive gas atmospheres has to be classified by the evaluation of the evaporation rate of flammable liquid leakage. The evaporation rate is an important factor to determine the zones classification and hazardous area distance. However, there is no systematic method or rule for the estimation of evaporation rate in these standards and the first principle equations of a evaporation rate are very difficult. Thus, it is really hard for industrial workplaces to employ these equations. Thus, this problem can trigger inaccurate results for evaluating evaporation range. In this study, empirical models for estimating an evaporation rate of flammable liquid have been developed to tackle this problem. Throughout the sensitivity analysis of the first principle equations, it can be found that main factors for the evaporation rate are wind speed and temperature and empirical models have to be nonlinear. Polynomial regression is employed to build empirical models. Methanol, benzene, para-xylene and toluene are selected as case studies to verify the accuracy of empirical models.

Sliding Mode Control of SPMSM Drivers: An Online Gain Tuning Approach with Unknown System Parameters

  • Jung, Jin-Woo;Leu, Viet Quoc;Dang, Dong Quang;Choi, Han Ho;Kim, Tae Heoung
    • Journal of Power Electronics
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    • v.14 no.5
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    • pp.980-988
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    • 2014
  • This paper proposes an online gain tuning algorithm for a robust sliding mode speed controller of surface-mounted permanent magnet synchronous motor (SPMSM) drives. The proposed controller is constructed by a fuzzy neural network control (FNNC) term and a sliding mode control (SMC) term. Based on a fuzzy neural network, the first term is designed to approximate the nonlinear factors while the second term is used to stabilize the system dynamics by employing an online tuning rule. Therefore, unlike conventional speed controllers, the proposed control scheme does not require any knowledge of the system parameters. As a result, it is very robust to system parameter variations. The stability evaluation of the proposed control system is fully described based on the Lyapunov theory and related lemmas. For comparison purposes, a conventional sliding mode control (SMC) scheme is also tested under the same conditions as the proposed control method. It can be seen from the experimental results that the proposed SMC scheme exhibits better control performance (i.e., faster and more robust dynamic behavior, and a smaller steady-state error) than the conventional SMC method.

Measurement of Transient Current by using the Rogowski Coil (로고우스키코일을 이용한 과도전류의 측정)

  • 이복희;길경석;정승수;정상진
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.43 no.7
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    • pp.1206-1213
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    • 1994
  • This paper presents the operation principle and design rule of the Rogowski coil which can measure the transient current and describes the calibration and application experimental results for performance evaluation. It is obtained that the response curves of the Robowski coil with the turns of 300 and the passive integrator to sinusoidal input give a good linearity up to the frequency of 500 [kHz] and the current measurement system gaving the Rogowski coil is the frequency bandwidth of 40 [Hz]~700 [kHz]. As an application experiment for the fabricated modeling power transmission line, the impulse current, which limitates the direct lightning return stroke to overhead ground wire, is measured by the Rogowski coil and its fast Fourier transformation is carried out. The equivalent circuit of the Rogowski coil considering the stray capacitances is proposed, and the theoretical analysis is in good agreement with the measurement results. Also, it is found that for high frequency domain the stray capacitance such as a distributed capacitance to the shield and the capacitance between windings of coil should be considered in designing the Rogowski coils since the resonance originates from the stray capacitance and the self-inductance of the Rogowski coil.

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