• Korean Journal of Clinical Pharmacy
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• v.28 no.3
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• pp.174-180
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• 2018

Objective: Clostridium difficile Infection (CDI) is one of the common nosocomial infections. As elderly population increases, the proper treatment has been emphasized. We investigated the risk factors associated with CDI unimprovement in elderly patients. Furthermore, we performed drug use evaluation of old CDI patients and oldest-old CDI patients. Methods: It was a retrospective study using electronic medical record at Kangbuk Samsung Medical Center (KBSMC) from January 2016 to December 2017. Seventy three patients aged 65 years or older, diagnosed with CDI by Clostridium difficile Toxin B Gene [Xpert] were screened and they were assessed for risk factors regarding unimprovement status. We also evaluated drug use evaluation in old patients ($65{\leq}age$<80) and oldest-old patients ($80{\leq}age$) by assessing the use of initial therapy, severity, dose, route, treatment course, days of use, total days of use and treatment outcome of initial therapy. Results: Out of 73 patients aged over 65 years, four patients were excluded because they did not receive any treatment. There were 31 improved patients and 38 unimproved patients after initial therapy. We were able to find out patients with surgical comorbidity or endocrine comorbidity (especially, diabetes mellitus) had 2.885 more risk of becoming unimproved than those patients without surgical comorbidity or endocrine comorbidity. Drug use evaluation for CDI was generally fair, but vancomycin as initial therapy is more recommended than metronidazole. Conclusion: Although age, antibiotics exposure, use of antacids are all important risk factors for CDI, our result did not show statistical significance for these risk factors. However, the study is meaningful because the number of elderly population keeps increasing and recently updated guideline suggests the use of vancomycin as drug of choice for CDI.

• Korean Journal of Clinical Pharmacy
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• v.30 no.3
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• pp.196-205
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• 2020

Background: The indication of denosumab for osteoporosis was expanded from second-line to first-line therapy in 2019. The aim of this study was to evaluate the efficacy of denosumab as both first- and second-line therapy in postmenopausal women with osteoporosis and osteopenia with risk factors by using the Fracture Risk Assessment Tool (FRAX). Methods: We conducted a medication use evaluation of denosumab in 98 patients who had been treated three or more times for osteoporosis or osteopenia at Chungnam National University Hospital from July 1^st, 2017 to January 31^st, 2020. Risk factors were identified using quantitative N-gram analyses of FRAX estimations. Patient information, including menopause status and results of bone mineral density tests (T-score), was obtained from electronic medical records. Results: Age, body mass index (BMI), prior medication use, and T-score were identified as risk factors and were included as variables in the evaluation of denosumab use. Since no significant differences were detected between groups, denosumab is likely effective regardless of age or BMI. In addition, no significant difference was detected in T-scores following denosumab treatment, between groups who took bisphosphonates and selective estrogen receptor modulators (SERMs) with denosumab as first-line therapy for postmenopausal osteoporosis. Denosumab may, therefore, be effective as second-line therapy. Conclusion: Efficacy of denosumab was evaluated in postmenopausal women with osteoporosis. Denosumab may be used as first- and second-line therapy regardless of age, BMI, and prior use of bisphosphonates and SERMs.

• Journal of the Korean Society of Clothing and Textiles
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• v.23 no.8
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• pp.1194-1205
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• 1999

The hand characteristics of bast blended fabrics are studied by a subective evaluation method. To offer basic data for development of better hand of bast fiber fabrics customer's hand preference surveys are executed as well. IN this study 51 varieties of linen or ramie blended fabrics of various blending ratio density and thickness and Hansan ramie Chinese ramie and a Shingosen fabics of various blending ratio density and thickness and Hansan ramie Chinese ramie and a Shingosen farbic and used. To evaluate the hand of the fabrics subjectively nine ranks' semantic differential scale questions of 26 items are developed with adjective pairs. A seven ranks' scale is also developed to evaluate hand preferences in blouse and jacket cloths, Through subjective evaluation of bast blended fabrics the 26 items could be classified into seven kinds of hand classification : surface characteristics extensibility/drapability felling of heaviness stiffness resilience moisture property and feeling of density. The cumulative variance value explained by these seven factors is 67.18% According to the results of fabrics' preference by age groups no significant differences are found in blouse cloths but a few significant differences are found among different age groups in jacket clothes. However experts and non-experts show considerable differences on preference It can be concluded that fabrics' preference I more dependent on professionality than on age. In the survey experts. However more drapery cloths are preferred by experts and cloths with drier touch are preferred by non-experts. Experts prefer rougher less even less winding heavier and sparser fabrics but non-experts prefer rougher lighter thinner and stiffer fabrics as jacket cloths.

• Journal of the Korean Society of Clothing and Textiles
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• v.18 no.3
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• pp.311-326
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• 1994

The purpose of this study was to identify 1) the effect of two contexts (job interview, Informal outing) and clothing cues (type, style, color) on male impresssions 2) the effect of perceiver's age on male impressions created by the clothing cues and contexts. The subjects consisted of 256 male undergraduate students and 256 middle-aged men. The experimental materials developed for this study were a set of stimuli and response scales. The stimuli were 8 color photographs of drawings of a male figure in clothing which were manipulated in two levels, each of three clothing cues including type, style and color. The experimental design was full factorial design of $(2^4contex^2{\times}clothing type^2{times}clthing color^2$. Each of the 16 sub-samples includes 16 subjects from the two perceiver group. Questionnaires used to measure perceivers responses to the stimuli were 7-point semantic differential scales composed of 37 bipolar adjectives representing personal traits. The data was processed by factor analysis, ANOVA, multiple classification analysis, Duncan's multiple range test. The major findings drawn from this study were as follows: 1. Three factors emerged to account for the dimensional structure of the impressions of the male figure in clothing in two social situations. These factors involved evaluation, activity and uniqueness. 2. The contexts, clothing types and clothing styles had significant effects on evaluation, activity and uniqueness. The clothing styles had a considerable effect on both evaluation and uniqueness while the clothing types affected activity. The clothing color had least effect on the impression and had only moderate effect on evaluation. 3. Perceiver's age influenced impressions formed by the social contexts and clothing cues. Male college students were least affected by contexts and clothing cues, while middle-aged men wert affected most.

• Korean Journal of Poultry Science
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• v.45 no.1
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• pp.63-71
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• 2018

This study was conducted to evaluate the effect of age of laying hens on egg internal and external qualities. A total of 8,300 eggs were randomly collected from 15 grading & packaging (GP) centers, and 50 eggs per farm during April to May in 2015. Age of laying hens ranged from 18 to 65 weeks of age and they were classified into 5 age groups (18~25, 26~35, 36~45, 46~55, and 56~65 weeks). Egg weight increased, but the Haugh unit decreased as the age of laying hens increased. Yolk color was higher in eggs laid from 25~35 weeks of laying hens compared with that of 18~25-weeks-old chickens. The incidence of dirty eggs was highest (P<0.05) in 18~25 week group and remained constant after 26 weeks. Among eggshell defects, speckled and pimpled eggs increased as the age of laying hens increased. The incidence of calcium deposits and misshapen eggs was highest during 18~25 weeks of age and remained constant after 26 weeks. The percentage of total eggshell cracks increased as the age of laying hens increased. Among eggshell cracks, star- and hair-like cracks were frequently noted. The percentage of meat spot was higher than that of blood spot and their incidence was highest among the 56~65 week group. Age of laying hens significantly increased egg weight, incidence of pimpled or speckled eggs, star- or hair-like cracks, and meat spot. On the other hand, a significant negative interaction between age of laying hens and the Haugh unit was noted. In conclusion, our study revealed that the age of laying hens affected internal and external egg qualities.

• International Journal of Computer Science & Network Security
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• v.22 no.12
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• pp.239-244
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• 2022

The study aimed to build a program in activities for early childhood students to develop some of the basic skills necessary for the age of artificial intelligence, to achieve the objectives of the study , the researcher used the experimental design, and the research sample consisted of 37 early childhood students. The study used the following tools: Experimental treatment subject: the proposed program in the activities, Measurement and evaluation tool: testing the basic skills needed for the age of artificial intelligence. The study concluded several results: There is a statistically significant difference (α≤0.05) between the average grades of the early childhood students in the research group in the tribal and remote measurements to test the basic skills necessary for the age of artificial intelligence in favor of the students grades in the dimensional measurements. Practical application of the study through benefiting from the proposed program of activities prepared in the current study in planning and implementing activities to develop the basic skills necessary for the age of artificial intelligence among early childhood students.

• Journal of the Korean Home Economics Association
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• v.29 no.2
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• pp.241-248
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• 1991

The aim of this study is to propose the criteria for a evaluation model of the lifetime household work and organize the model. The results were as follows: Three criteria for a evaluation model of the life-time household work were proposed. $\circled1$ An appropriate framework of the evaluation model should be based on the transition of the family life. $\circled2$ The model should include major variables influencing the value of household work of homemaker. $\circled3$ The model should be flexible enough to accommodate various evaluation methods, and should reflect idiosyncracies of different evaluation methods. In view of the criteria stated above, the present study is based on the family life cycle framework. And the age of the last offspring exhibits a consistent major influence in the evaluation based on the household work hours, while the education level of homemakers shows a consistent major influence in the evaluation based on household worker. So as to reflect these two major variables in the family life cycle framework.

• Proceedings of the KSPS conference
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• 2005.11a
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• pp.141-144
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• 2005

The purpose of this study is to identify the acoustic changes according to age and to provide the evaluation criteria of elderly voice. The number of 120 Korean adults (three age groups * two sex groups) proceeded sustained three vowels, read apart of 'Taking a walk' and explained a picture. The data was analyzed acoustically with MDVP of CSL. The results showed that: 1)there was statistically most significant changes in sex and age in F0 than the others but no significant in Shimmer. 2)acoustic parameters were changed from young adulthood to old age. Different patterns of change with aging were observed in men and women.

• Proceedings of the Korea Concrete Institute Conference
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• 1996.10a
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• pp.352-357
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• 1996

In hardening massive concrete, the heat of hydation gives rise to considerable thermal gradientsand thermal stresses, which might cause early age cracking. This paper deals with the results of evaluation of hydration heat of low hear concrete, using Belite rich cement (low heat cement) and compared with OPC, slag added cement and fly ash addedcement. Result of evaluation of hydration are presented in this paper. The concrete made with Belite rich cement gets low temperature of center point and low thermal gradients between surface and center points.

• Journal of agricultural medicine and community health
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• v.22 no.2
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• pp.195-213
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• 1997

This study was carried out to investigate several effects of smoking and alcohol-drinking on the health of rural residents. The subjects were 710 people (325 males and 385 females) in rural area, Young-Duk Gun, Kyungbuk, Korea. The data were collected by medical students trained for this study during 4 days from 31 August, 1996. Questionnaire contents were general social characteristics, period of the agriculture, smoking history, alcohol-drinking history, some psychosomatic symptoms and self-evaluation for health. The results obtained are as follows : 1. Positive rates of the some psychosomatic symptoms and self-evaluation for health were higher in female than in male and were significantly increased as the as increased(p<0.05). 2. Smoking rate was 56.9% in male and 4.9% in female. In positive rates of the some psychosomatic symptoms and self-evaluation for health in male, 'insomnia' was only significantly lower in ex-smoker than in smoker and non-smoker(p<0.05). Other items were significantly not different. 3. Prevalence rate of alcohol drinker was 54.8% in male and 17.1% in female and the alcoholism was 8.3% in male and 0.8% in female. Positive rate of the some psychosomatic symptoms and self-evaluation for health in male were significantly not different. 4. The scores of self-evaluation for health was divided into two groups under two point and over three. And the analysis of multiple logistic regression shows that there were significant relationship with age and sex. This study suggests that some psychosomatic symptoms and self-evaluation for health were significant relationship with age and sex but not smoking and alcohol-drinking.