• Title/Summary/Keyword: estimation activities

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Lipid-lowering and hepatoprotective effects of Vitis vinifera dried seeds on paracetamol-induced hepatotoxicity in rats

  • Almajwal, Ali Madi;Elsadek, Mohamed Farouk
    • Nutrition Research and Practice
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    • v.9 no.1
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    • pp.37-42
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    • 2015
  • BACKGROUND/OBJECTIVES: Red grape seeds as functional food are a good source of important bioactive components such as phenolics and antioxidants, which decrease oxidative stress that contributes to the pathogenesis of hepatotoxicity. The current study was conducted in order to evaluate the protective effect of red grape dried seeds (RGDS) on antioxidant properties, lipid metabolism, and liver and kidney functions of rats with paracetamol (750 mg/kg) induced hepatotoxicity. MATERIALS/METHODS: RGDS was added to the basal diet at 5, 10, and 20%. Thirty five adult male rats were assigned to five groups (n = 7) for a six-week feeding period; group (1) normal control, group (2) induced control, groups (3, 4, and 5) fed a diet with RGPS at different levels, 5, 10, and 20%, respectively. At the end of the feeding period, animals' blood and tissues were collected for estimation of serum lipid profile, serum liver, and kidney biomarkers. The protection was measured by detecting lipid peroxidation (LPO), glutathione (GSH), superoxide dismutase (SOD), Catalase (CAT) (in liver tissues), and liver histological examination. RESULTS: The results showed a significant (P < 0.05) decrease in levels of serum cholesterol, triglycerides, low density lipoprotein (LDL-C), and very low density lipoprotein (VLDL-C), with a significant increase in level of high density lipoprotein (HDL-C) for RGDS groups compared to induced control. Rats administered a diet containing RGDS levels produced significant (P < 0.05) hepatoprotection by decreasing the activities of liver enzymes, kidney parameters, and lipid peroxidation, while levels of GSH, SOD, and CAT were increased significantly to near the normal levels. CONCLUSION: The RGDS 20% group was more effective than others against hepatotoxicity of paracetamol, which may be attributed to RGDS total phenols and antioxidant contents, which were 1.438 mg and 1.231 mg, respectively.

Development and Application of a Subject Substitute STEAM Lesson in Elementary School Science Education (초등과학교육에서 차시대체형 STEAM 수업 개발 및 적용)

  • Chae, Dong-Hyun;Moon, Byoung-Chan;Kim, Eun-Jeong
    • Journal of the Korean Society of Earth Science Education
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    • v.7 no.3
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    • pp.327-337
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    • 2014
  • In this research, a subject substitute STEAM program was developed in context of a trend of STEAM education and a new science contents in a 2009 revised curriculum, which can replace the 2009 revised curriculum contents of 'Sound' unit in the third and the fourth grade. The developed program was taught to the 4th graders in a field. After applying the program, how students acknowledge the subject substitute STEAM program was analyzed through questionnaire. The research results were as follows. First, the subject substitute STEAM program of 3 sub programs was developed with centered around 'sound' unit for 4th graders. Second, students made a positive estimation of the STEAM program because of various activities and learning subject related to daily life. Third, they considered difficult term, necessary craft skills in creative design, understanding scientific principle and a lot of necessary time as difficulties of the STEAM program. And they also recognized that making stuff activity and learning aid material like activity sheet, picture and video helped to understand a lesson. Lastly, students had a positive thinking or negative thinking about STEAM program before they learn. But after learning the STEAM program, all of them showed their positive attitude to the STEAM program.

Estimation of Antibacterial Properties of Chlorophyta, Rhodophyta and Haptophyta Microalgae Species

  • Imran Bashir, Khawaja Muhammad;Lee, Jae-Hyeon;Petermann, Maike Julia;Shah, Abid Ali;Jeong, Su-Jin;Kim, Moo-Sang;Park, Nam-Gyu;Cho, Man-Gi
    • Microbiology and Biotechnology Letters
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    • v.46 no.3
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    • pp.225-233
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    • 2018
  • In this exploratory study, eight types of microalgae from different phyla (Chlamydomonas reinhardtii, Chlorella species, Haematococcus pluvialis, Porphyridium purpureum, Porphyridium cruentum, Isochrysis species, Isochrysis galbana, and Pavlova lutheri) were tested for their antibacterial activities against eight target pathogenic bacterial strains. The agar well diffusion method and broth micro dilution assay were conducted to estimate the antibacterial activity. Microalgae cell-free supernatants, exopolysaccharides (EPS), water, and organic solvent extracts were used for inhibition analysis. EPS extracted from P. lutheri showed activity against Bacillus subtilis and Pseudomonas aeruginosa. Inhibition zone diameters of 14-20 mm were recorded on agar plates, while the minimum inhibitory concentrations in the broth micro dilution assay were $0.39-25mg\;ml^{-1}$. During this study, haptophyte microalgae, Isochrysis species, and P. lutheri extracts showed the highest activity against most of the tested pathogenic bacterial strains, while most of the extracts were active against the important foodborne pathogen P. aeruginosa. This study showed promising results regarding important microalgae phyla, which will further aid research related to extracts and exploitation of bioactive metabolic compounds in the food and pharmaceutical industries.

Analysis of Income-led Growth Path Induced by Government and Consumption Expenditures (정부지출과 소비지출에 의한 소득주도성장 경로 분석)

  • Rhee, Hyun-Jae
    • The Journal of the Korea Contents Association
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    • v.20 no.7
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    • pp.602-617
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    • 2020
  • The aim of this study is to evaluate the effects of income-led growth path induced by government and consumption expenditures. Six of Nordic countries, Latin American countries and South Korea are selected for this purpose due to the fact that these countries have been pursuing income-led growth policy for more than the last decade except South Korea. The structural equation is formulated based on the government and consumption expenditures with lagged variable, and the GLMs estimation is employed for empirical analysis. Although the impacts are not overwhelmingly effective, empirical evidence suggests that income-led growth path contributes to stimulate economic activities which are associated with increasing in national income in Nordic countries and South Korea. However, the income-led growth path is quite weakly operated. Furthermore, it is even unstable in Latin American countries. In addition to this, the policy target would rather be focused on middle consumption group than low consumption group. Overall, it would be concluded that the income-led growth policy should be implemented for complementary purpose. And, it also has to be mentioned that sustainable growth may not be achievable by this policy.

A development of CO2 emission estimation model based on the spatial configuration of street networks, building capacity and building usages (도로부문 이산화탄소 배출량 추정 모델의 개발: 도로망, 건물규모, 건물용도의 공간배치를 중심으로)

  • Kim, Young-Ook;Kim, Kyoung-Yong;Park, Hoon-Tae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3879-3887
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    • 2014
  • This paper presents a model to estimate the amount of $CO_2$ emitted by cars in cities. Based on the spatial configuration of street networks, building masses and usages, it first develops a deductive model to combine them in a way to account for $CO_2$ emission amount by cars. It then proceed to validate model behaviours through a series of simulations on some ideal urban settings and finally calibrate it following its real application to the five case study cities in Korea. In contrast to the conventional 'top-down' approaches, we expect our model to have high utilities, particularly in the field of urban planning and design, where we cannot but deal directly with the spatial configuration of urban components and microscopic human activities.

A Schematic Estimation Development of the CO2 Emission in the Maintenance of Repair of Apartment Housing (개·보수 유지관리부문의 이산화탄소 배출량 간이 산정방법에 관한 연구)

  • Lee, KangHee;Ahn, YoungHan;Chae, ChangU
    • KIEAE Journal
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    • v.13 no.6
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    • pp.99-104
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    • 2013
  • Many activities associated with the construction and habitation of buildings are connected with issues affecting the environment such as global warming, climate change, and consumption of valuable natural resources such as fossil fuels. To minimize negative impacts on the environment, the building industry worldwide has implemented green building practices in many countries. One of the main green strategies is to reduce greenhouse gas emissions caused by residential structures because they are most substantially connected with global warming and climate change. To determine the actual quantity of green house gas emissions caused by the construction and use of a building, it is important to analyze total greenhouse gas emissions over the life cycle of buildings including construction, operation & maintenance(O&M) and demolition stages. Many studies suggest methods to calculate greenhouse gas emissions at the construction stage, but the literature addressing greenhouse gas emissions at the O & M stage is limited. A year-long study was conducted utilizing the deterioration method to calculate greenhouse gas emissions at the O & M stage of building life for condominium types of buildings in South Korea. Through this research, it is possible to analyze greenhouse gas emissions of buildings at the O & M stage, the longest span of the life cycle, and eventually help to calculate total greenhouse gas emissions over the life cycle of the building.

Model for Ionic Species Estimation in Soil Solutio (토양용액의 이온조성 추정모델)

  • Kim, Yoo-Hak;Yoon, Jung-Hui;Jung, Beung-Gan;Kim, Min-Kyun
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.3
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    • pp.213-236
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    • 2001
  • The ionic composition of soil solution is related to a nutrient uptake by plant. Many models for estimating ionic composition of solution have been developed, and most of them have been used for calculating a content of mineral and ionic species in a geochemical point of view. An approximation model considering both cation and anion in soil solution was developed. Variables such as pH, Eh, EC, cations(K, Ca, Mg. Na, Fe, Mn, Al, $NH_4{^+}$), anions(Si, S, P, CY, $NO_3{^-}$, $HCO_3{^-}$ and chemical equilibria of ionic species in soil solution were input into Excel sheet. The activities of soluble ion, ionpairs and complexes of input element were estimated by Newton-Raphson method using conditional equilibrium constant calculated by Davies equation and special models. Equilibrium contents of insoluble minerals and complexes were also calculated.

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Estimation of ELF-MF Exposure Levels in the Korean Population through 24-Hour Personal Exposure (개인 노출량 조사를 통한 한국인의 극저주파 자기장 노출 수준)

  • Jung, Joon-Sig;Kim, Keun-Young;Hong, Seung-Cheol;Cho, Yong-Sung;Kim, Yoon-Shin
    • Journal of Environmental Health Sciences
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    • v.38 no.1
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    • pp.18-30
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    • 2012
  • Objectives: The purpose of this study was to estimate the exposure level to extremely low frequency-magnetic fields (ELF-MF) among a selected Korean population using 24-hour personal exposure measurement. Methods: Participants were randomly selected for the measurement of MF exposure under the assumption that the subjects are representative of the overall Korean population. Levels of personal exposure to MF were measured according to the subject's daily activities. Results: The 24-hour time-weighted average (TWA) of 250 participants was $1.56{\pm}4.56$ mG (GM, GSD: 0.79, 2.46 mG). Personal exposure levels for females were higher than for males. The highest personal exposure level was shown in the age group between 20-60 years old. Personal exposure levels according to job category were higher for the non-occupational group than for the occupational group. Conclusions: Our results showed MF exposure exceeding 2 mG per day among 11.3% of the Korean population, indicating a somewhat higher percentage compared to the EMF RAPID Program's results for the U.S population.

A Models of Economic Analysis in Safety Diagnosis for Remodeling Strategies of Apartment Housing (공동주택의 리모델링 전략을 위한 안전진단의 경제성분석 모델)

  • Seo Kwang-Jun;Choi Mi-Ra;Shin Nam-Soo
    • Korean Journal of Construction Engineering and Management
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    • v.6 no.4 s.26
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    • pp.164-171
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    • 2005
  • The importance of the life cycle cost analysis(LCCA) for apartment housing remodeling projects has been fully recognized over the last decade. Accordingly theoretical models, guidelines, and supporting software systems were developed for the life cycle cost analysis of apartment housing remodeling systems. However, the level of consensus on LCCA results is still low due to the lack of reliable data on remodeling activities for safety diagnosis. in order to predict the reliability based LCCA of the given case, suggested the remodeling strategies level after reviewing other related materials. Apply the real information of the economic index. And based on such analytical measures, remodeling and operation cost and LCC in remodeling strategies level have been predicted; suggests the basic information about remodeling interventions level for the apartment housing. The LCC analysis models and the fuzzy logic based safety assessment presented in this study can greatly contribute to the value-oriented design alternative selection, estimation of the economic analysis, and the allocation of budget for apartm.

Telephone Survey for Grasping Clinical Actual State of Bloodletting Therapeutics in Korea (국내 자락(사혈)요법 임상 실태 파악을 위한 전화조사)

  • Han, Chang-Hyun;Kim, Seon-Woong;Lee, Seung-Deok;Shin, Mi-Suk;Shin, Seon-Hwa;Choi, Sun-Mi
    • Journal of Acupuncture Research
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    • v.23 no.6
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    • pp.177-187
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    • 2006
  • Objectives : Bloodletting therapeutics is one of the most popular oriental treatments in Korea. In this study, we operate the Telephone Survey for grasping clinical actual state bloodletting therapeutics in Korea. Methods : The list of the Korean medical doctors with experiences more than 10 years is provided by the Association of the Korean Oriental Medicine. A stratified random sample of Korean medical doctors is drawn for the telephone interviews. We choose a bound on the error of estimation equal to 3.2 percentage, and the sample size is 321 for the national sample. We develop a questionnaire for telephone interviews. We carefully design the questionnaire to minimize non-sampling errors by using the focus group activities and the pretest. We give the details of the results based on the sample design. Also, we present some socialdemograhpic characteristics for the samples. Telephone interviews with them were conducted by the well-trained interviewers of College of Korean Medicine student from 11th May 2006 to 17th May 2006. Results : 1. Two hundred eighty eight(89.4%) out of 322 Korean oriental medical doctors used bloodletting therapeutics. 2. The most common main bloodletting treatment is reported by patients was musculo-skeletal disorder(60.2%). 3. Two hundred ninety one(90.3%) out of 322 Korean oriental medical doctors opposed that commercial using bloodletting without medical diagnosis. Conclusion : Bloodletting therapeutics is one of the most popular oriental treatments in Korea. The majority(89.4%) of Korean medical doctors used bloodletting therapeutics in this survey.

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