• Title/Summary/Keyword: essential element

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Determination of Iodine Contents in Ten kinds of Frequently used Oriental Herb Medicinal Products for Cancer Patient (암환자에게 다빈도로 활용되는 한약제제 10종에 대한 요오드의 함량 분석)

  • Lee, Chang-Hee;Choi, Jung-Eun;Kim, Sun-Ha;Chung, Yong-Sam;Moon, Jong-Hwa;Yoo, Hwa-Seung
    • Journal of Korean Traditional Oncology
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    • v.16 no.1
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    • pp.41-53
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    • 2011
  • Background and Objectives: Iodine is an essential constituent of the thyroid hormones associated with the growth and development of humans and animals as an inorganic nutrition. This element may be accumulated in human blood, tissues and body through the intake of foodstuffs, a beverage, a nutritional supplement and a medicine, among others. The aim of the research is to find out a better medicinal stuff for the thyroid cancer patient who required a low level of iodine diet. Methods: Neutron activation analysis (NAA) used for the iodine analysis is one of nuclear analytical techniques using radiation and radioisotopes and very useful as sensitive analytical technique for performing both qualitative and quantitative multi-elemental non-destructive analysis of major, minor and trace components in variety of environmental and biological materials. In this study, iodine contents in ten kinds of oriental herb medicinal products, which is frequently used to cancer patients are determined by using instrumental neutron activation analysis (INAA) at the HANARO research reactor. The samples prescribed are manufactured as powdered form for taking medicine easily. The analytical quality control is performed to assure an uncertainty of the measurement and to compensate the measured data using a biological certified reference material, NIST SRM 1572, Citrus Leaves. The measured value is $1.89{\pm}0.35mg/kg$, and the relative error is 2.88%, and relative standard deviation is 19 % due to high counting error by small counts of gamma ray spectrum. The standard deviations for other elements such as Cl, K, Mn and Na were in the range of 2 to 8%. Result: The level of iodine contents of Biki-huan, Chungryong-huan and Chungcho-huan, samples detected is less than 6 mg/kg except Hangam Plus sample (more than 210 mg/kg) and six samples were not detected. Iodine in the samples of Shoxiho-tang, Shopunghualhyl-tang, Shocungryong-tang, Banhasaxim-tang, Insampaedox-san and Myunyuk Plus were not measured, but possible level of content can be estimated from the detection limits. In addition, the concentrations of some major elements like Cl, K, Mn, Na, in the samples were determined with the detection limits. Conclusions: Most of samples showed low iodine contents of less than 6 mg/kg but it turned out that most of testing samples can be used to classify the level of iodine diet samples considering the recommended low level of iodine diet 50 ${\mu}g$/day, and a better medicinal stuff for the thyroid cancer patient can be found.

Activation Factors of Industry Cooperation through Comparison Study on Domestic and International Industry Cooperation Programs (국내외 산학협력프로그램 비교를 통한 산학협력 활성화 방안 연구)

  • Kim, Hye Sun;Kim, Jong Boo;Kim, Hyoung Ro
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.9 no.2
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    • pp.187-200
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    • 2014
  • Industry Cooperation is not the choice of national development but the inevitable component in the world. Industry cooperation results of the reconstruction of the country is an important place as an essential element of the economic development of the national policy in the major economies. Despite several changes in the international economic environment, United States, Canada, Finland, Sweden, Israel settled and maintaining the sustainable development of the countries which successfully established Industry-University Cooperation or Industry-Acaemy Cooperation system in history. In this study, delivered to the realistic ways of Industry cooperation through comparison study on domestic and international cooperation programs. The new activation programs of industry academic cooperation are delivered, that is, The bonus payments system of technology development patent and free technology transfer for joint development, bonus points system and evaluation indicators for joint capacity building program which participate student, industry and academic sector, step-by-step training. system for total employment and entrepreneurship at the same time strengthening management training programs and education opportunity gives to the benefits for the community members. Finally, Intellectual property expert matching program which develops basis of technology trader and expert maps in the smallest unit by administrative area. practice the internet information search services in national wide network for this matching program and government office dedicated to staffing for technology transfer.

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A new feature specification for vowel height (모음 높이의 새로운 표기법에 대하여)

  • Park Cheon-Bae
    • MALSORI
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    • no.27_28
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    • pp.27-56
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    • 1994
  • Processes involving the change of vowel height are natural enough to be found in many languages. It is essential to have a better feature specification for vowel height to grasp these processes properly, Standard Phonology adopts the binary feature system, and vowel height is represented by the two features, i.e., [\pm high] and [\pm low]. This has its own merits. But it is defective because it is misleading when we count the number of features used in a rule to compare the naturalness of rules. This feature system also cannot represent more than three degrees of height, We wi31 discard the binary features for vowel height. We consider to adopt the multivalued feature [n high] for the property of height. However, this feature cannot avoid the arbitrariness resulting from the number values denoting vowel height. It is not easy to expect whether the number in question is the largest or not It also is impossible to decide whether a larger number denotes a higher vowel or a lower vowel. Furthermore this feature specification requires an ad hoc condition such as n > 3 or n \geq 2, whenever we want to refer to a natural class including more than one degree of height The altelnative might be Particle Phonology, or Dependency Phonology. These might be apt for multivalued vowel height systems, as their supporters argue. However, the feature specification of Particle Phonology will be discarded because it does not observe strictly the assumption that the number of the particle a is decisive in representing the height. One a in a representation can denote variant degrees of height such as [e], [I], [a], [a ] and [e ]. This also means that we cannot represent natural classes in terms of the number of the particle a, Dependency Phonology also has problems in specifying a degree of vowel height by the dependency relations between the elements. There is no unique element to represent vowel height since every property has to be defined in terms of the dependency relations between two or more elements, As a result it is difficult to formulate a rule for vowel height change, especially when the phenomenon involves a chain of vowel shifts. Therefore, we suggest a new feature specification for vowel height (see Chapter 3). This specification resorts to a single feature H and a few >'s which refer exclusively to the degree of the tongue height when a vowel is pronounced. It can cope with more than three degrees of height because it is fundamentally a multivalued scalar feature. This feature also obviates the ad hoc condition for a natural class while the [n high] type of multivalued feature suffers from it. Also this feature specification conforms to our expection that the notation should become simpler as the generality of the class increases, in that the fewer angled brackets are used, the more vowels are included, Incidentally, it has also to be noted that, by adopting a single feature for vowel height, it is possible to formulate a simpler version of rules involving the changes of vowel height especially when they involve vowel shifts found in many languages.

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Understanding and predicting physical properties of rocks through pore-scale numerical simulations (공극스케일에서의 시뮬레이션을 통한 암석물성의 이해와 예측)

  • Keehm, Young-Seuk;Nur, Amos
    • 한국지구물리탐사학회:학술대회논문집
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    • 2006.06a
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    • pp.201-206
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    • 2006
  • Earth sciences is undergoing a gradual but massive shift from description of the earth and earth systems, toward process modeling, simulation, and process visualization. This shift is very challenging because the underlying physical and chemical processes are often nonlinear and coupled. In addition, we are especially challenged when the processes take place in strongly heterogeneous systems. An example is two-phase fluid flow in rocks, which is a nonlinear, coupled and time-dependent problem and occurs in complex porous media. To understand and simulate these complex processes, the knowledge of underlying pore-scale processes is essential. This paper presents a new attempt to use pore-scale simulations for understanding physical properties of rocks. A rigorous pore-scale simulator requires three important traits: reliability, efficiency, and ability to handle complex microstructures. We use the Lattice-Boltzmann (LB) method for singleand two-phase flow properties, finite-element methods (FEM) for elastic and electrical properties of rocks. These rigorous pore-scale simulators can significantly complement the physical laboratory, with several distinct advantages: (1) rigorous prediction of the physical properties, (2) interrelations among the different rock properties in a given pore geometry, and (3) simulation of dynamic problems, which describe coupled, nonlinear, transient and complex behavior of Earth systems.

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Perception of Pre-service Teacher who Participated into Liaison Teacher on the Gifted Education (영재교육원의 보조교사 활동에 참여한 예비교사의 영재교육에 대한 인식)

  • Kim, Jeongrye;Kim, Sunja;Park, Jongwook
    • Journal of Science Education
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    • v.38 no.2
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    • pp.317-330
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    • 2014
  • The perception of pre-service teachers who participated as liaison teachers in the gifted education organization's different operating styles and the differences in the thoughts of these teachers were analyzed in this study. The inquiry survey was performed for 74 liaison teachers who had participated in the observational activities in the university annexed science gifted education center and the dormitory based gifted students education center supported by education of administration in Chungbuk Province. The individual in-depth interview was performed with 7 teachers based on the analyzed data. The perception of pre-service teachers who participated in as liaison teachers in the university annexed science gifted education center and the dormitory based gifted students education center was different from important element of the gifted and qualification of the teacher for gifted education. It was revealed that the differences between the education parts, education schedule and education methods of two the education centers, which were performed during the semester, influenced the perception of pre-service teachers who participated as the liaison teachers. The necessity of the systematic training on the observational skills and class contents were suggested as the essential support system for liaison teachers. The results of the study indicate that the gifted education organizations operating styles, the activities of liaison teachers, and pre-service teacher training program for gifted education emphasizes the long term actual guide experience at the education field for the gifted.

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Synergistic Increase of BDNF Release from Rat Primary Cortical Neuron by Combination of Several Medicinal Plant-Derived Compounds

  • Jeon, Se-Jin;Bak, Hae-Rang;Seo, Jung-Eun;Kwon, Kyung-Ja;Kang, Young-Sun;Kim, Hee-Jin;Cheong, Jae-Hoon;Ryu, Jong-Hoon;Ko, Kwang-Ho;Shin, Chan-Young
    • Biomolecules & Therapeutics
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    • v.18 no.1
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    • pp.39-47
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    • 2010
  • Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor involved in neuronal differentiation, plasticity, survival and regeneration. BDNF draws massive attention mainly due to the potential as a therapeutic target in neurological diseases such as depression and Alzheimer's disease. In a primary screening for the natural compounds enhancing BDNF release from cultured rat primary cortical neuron, we found that compounds such as baicalein, tanshinone IIa, cinnamic acid, epiberberine, genistein and wogonin among many others increased BDNF release. All the compounds at $0.1{\mu}M$ of concentration barely showed stimulatory effect on BDNF induction, however, their combination (mixture 1; baicalein, tanshinone IIa and cinnamic acid, mixture 2; epiberberine, genistein and wogonin) showed synergistic increase in BDNF release as well as mRNA and protein expression. The level of BDNF expression was comparable to the maximum BDNF stimulation attainable by a positive control oroxylin A ($20{\mu}M$) without cell toxicity as determined by MTT analysis. Both mixtures synergistically increased the phosphorylation of extracellular signal-regulated kinase (ERK) as well as cAMP response element binding protein (CREB), an immediate and essential regulator of BDNF expression. Similar to these results, mixture of these compounds synergistically inhibited the up-regulation of inducible nitric oxide synthase (iNOS) induced by lipopolysaccharide treatments in rat primary astrocytes. These results suggest that the combinatorial treatment of natural compounds in lower concentration might be a useful strategy to obtain sufficient BDNF stimulation in neurological disease condition such as depression, while minimizing potential side effects and toxicity of higher concentration of a single compound.

CFD analysis for effects of the crucible geometry on melt convection and growth behavior during sapphire single crystal growth by Kyropoulos process (사파이어 단결정의 Kyropoulos 성장시 도가니 형상에 따른 유동장 및 결정성장 거동의 CFD 해석)

  • Ryu, J.H.;Lee, W.J.;Lee, Y.C.;Jo, H.H.;Park, Y.H.
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.22 no.3
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    • pp.115-121
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    • 2012
  • Sapphire single crystals have been highlighted for epitaxial gallium nitride films in high-power laser and light emitting diode (LED) industries. Among the many crystal growth methods, the Kyropoulos process is an excellent commercial method for growing larger, high-optical-quality sapphire crystals with fewer defects. Because the properties and growth behavior of sapphire crystals are influenced largely by the temperature distribution and convection of molten sapphire during the manufacturing process, accurate predictions of the thermal fields and melt flow behavior are essential to design and optimize the Kyropoulos crystal growth process. In this study, computational fluid dynamic simulations were performed to examine the effects of the crucible geometry aspect ratio on melt convection during Kyropoulos sapphire crystal growth. The results through the evolution of various growth parameters on the temperature and velocity fields and convexity of the crystallization interface based on finite volume element simulations show that lower aspect ratio of the crucible geometry can be helpful for the quality of sapphire single crystal.

A Study on the Recognition Level of Employment and Overseas Employment among Students Majoring in Dental Technology (일부 치기공과 대학생들의 해외취업에 관한 의식 조사 연구)

  • Park, Nam-Gyu;Jung, Hyo-Kyung
    • Journal of Technologic Dentistry
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    • v.29 no.2
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    • pp.17-34
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    • 2007
  • This study was conducted to research into the recognition level of employment and overseas employment on 173 students majoring in dental technology at two colleges in Daegu metropolitan city and Jeju self-governing island through questionnaires which are recorded individually. The results are as follows. 1. About 31.8% students chose dental technician department taking their aptitude into consideration when they entered college. 52% students gained information about dental technology through internet, and 57.3% students among them, which was the highest level, were under age 20. 2. 48.6% students responded that they thought the level of satisfaction with major was average and there was a difference according to their ages among the level of satisfaction or dissatisfaction with their major and the previous knowledge of major they had gained before entering college. 75.1% students said they wouldn't transfer to other major even if they were given the chance, which was much higher than the opposite case. And only 2.3% students had dissatisfaction at their major, which means students majoring dental technology evaluate their major positively. 3. Most students(58.4%) wanted to get a job for living cost and 53.2% students took advice from their seniors or elderly people in choosing their jobs. 64.7% students answered they should have professional skills to get a good job, which was different according to their ages. In addition, 51.4% students of dental technology department regarded the opportunities to exert their abilities as the most important element in choosing their jobs. That means students value self-decision and selfrealization when they choose their jobs. 4. The majority of students(32.9%) preferred to work at the dental laboratory in dental college hospital as their workplace. Moreover, seniors over age 21 wanted to work in the field of porcelain and juniors under age 20 preferred to work in the implant part concerning the field which students wants to work. 5. About 91.3% students have ever heard about overseas employment and wanted to work abroad if given the opportunities(77.5%). This points out students have much interest in overseas employment and positive attitude. And there was a difference according to age and grade in case of the preferred country when they work abroad 6. The main barrier to overseas employment was a lack of communication ability(63.0%), therefore, students thought foreign language education should be activated to improve overseas employment(26.0%). To show this more specifically, juniors thought foreign language education and internship are most important factors(both are 21.4% alike), while seniors thought foreign language education is essential(24.6%) as a way to improve overseas employment. Students also thought that participation in language study club helps to prepare for overseas employment(69.4%). When putting all these survey results together, it's very important to develop people in advance who have job ability and language ability necessary for overseas employment as well as to improve job awareness in the field of dental technology. Consequently, it's needed to seek for various ways to get a overseas job through foreign language education and overseas internship.

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The Nature of Science Reflected in Exhibitions of Natural History Museums (자연사박물관의 전시에 반영된 과학의 본성)

  • Lee Sun-Kyung;Shin Myeong-Kyeong;Kim Chan-Jong
    • Journal of the Korean earth science society
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    • v.26 no.5
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    • pp.376-386
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    • 2005
  • This study investigated to describe how the nature of science is revealed in the four natural history museums in Korea. Natural history museums are well considered as informal settings of education, and the nature of science has been one of major topics stressed in science education. Therefore, the revelation of this topic is supposedly reflected in developing museum exhibitions. In each of the four target natural history museum or natural history exhibition, the representative exhibits subtitled by scientific inquiry and cases dealing with history of science were selected for the study. The analyzing exhibits focused on whether exhibitions were labeled with emphasis on declarative description or interpretative one. In analyzing the contents, the focus was on the concerns of scientists, scientific community, social and cultural aspects, uncertainty of scientific knowledge, and providing sufficient evidences. All things considered, it was hard to conclude that every target exhibit clearly considered the nature of science as an essential element, in designing and developing their exhibitions. More deliberate input of nature of science is suggested for worldly renowned natural history museums, because previous researches keep insisting that the nature of science would be more efficiently achieved in an informal educational setting rather than in classrooms.

A Case Study on the Inquiry Guidance Experiences of Pre-Service Science Teachers : Resolving the Dilemmas between Cognition and Practice of Inquiry (예비 과학교사의 탐구지도 경험에 관한 사례연구 : 탐구의 인식과 실천 사이의 딜레마 해소를 중심으로)

  • Cho, Sungmin;Baek, Jongho
    • Journal of The Korean Association For Science Education
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    • v.35 no.4
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    • pp.573-584
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    • 2015
  • Inquiry has been consistently emphasized in science education as a crucial element for learning. Although many researchers came to agree on the importance of scientific inquiry, authentic inquiry activities are hard to be actualized in an educational context. Therefore it is required to critically examine what teachers have difficulty in teaching inquiry. In this article, we looked into inquiry-based science activities in a small group setting where pre-service science teachers faced dilemmas between cognition and practice of inquiry. A case study was conducted on eight undergraduate students who are majoring in science education. The participants attended a weekly science program for middle school students in low SES as teaching assistants and mentors, and took full care of his/her mentees during open-inquiry activities. The results were drawn by analyzing participants' personal and group interviews, participant observations, self-reports, and others. The pre-service teachers viewed the knowledge and procedure of science as an essential factor in inquiry activities along with student's spontaneous attitude. However, in the process of performing inquiry, they faced several dilemmas between ideal cognition and real activities. The aspects of dilemmas could be summarized in three pairs of opposing concepts: 'diverging inquiry or converging science', 'interest-centered inquiry or learning-centered inquiry', and 'student as the subject or student with the insufficient expertise.' We discussed ways of resolving dilemmas and alternative perspectives on scientific inquiry.