• Yonsei Medical Journal
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• v.59 no.9
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• pp.1115-1122
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• 2018

Purpose: To investigate biomechanical properties of the cornea using a dynamic Scheimpflug analyzer according to age. Materials and Methods: In this prospective, cross-sectional, observational study, participants underwent ophthalmic investigations including corneal biomechanical properties, keratometric values, intraocular pressure (IOP), and manifest refraction spherical equivalent (MRSE). We determined the relationship of biomechanical parameters and ocular/systemic variables (participant's age, MRSE, IOP, and mean keratometric values) by piecewise regression analysis, association of biomechanical parameters with variables by Spearman's correlation and stepwise multiple regression analyses, and reference intervals (RI) by the bootstrap method. Results: This study included 217 eyes of 118 participants (20-81 years of age). Piecewise regression analysis between Corvis-central corneal thickness (CCT) and participant's age revealed that the optimal cut-off value of age was 45 years. No clear breakpoints were detected between the corneal biomechanical parameters and MRSE, IOP, and mean keratometric values. Corneal velocity, deformation amplitude, radius, maximal concave power, Corvis-CCT, and Corvis-IOP exhibited correlations with IOP, regardless of age (all ages, 20-44 years, and over 44 years). With smaller deformation amplitude and corneal velocity as well as increased CorvisIOP and Corvis-CCT, IOP became significantly increased. We provided the results of determination of confidence interval from RI data using bootstrap method in three separate age groups (all ages, 20-44 years, and over 44 years). Conclusion: We demonstrated multiple corneal biomechanical parameters according to age, and reported that the corneal biomechanical parameters are influenced by IOP.

• Journal of English Language & Literature
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• v.58 no.2
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• pp.217-247
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• 2012

This essay attempts to read Melville's Moby-Dick as a prefiguration of American pragmatism, especially Jamesian version of it. Underlying this project is the assumption that the American Romance and James's pragmatism partake in the enduring tradition of American thoughts and imagination. Despite the commonality in their roots, the continuity between these two products of American culture has received few critical assessments. The American Romance has rarely been discussed in terms of American pragmatism in part because critics have tended to narrowly define the latter as a kind of relativistic philosophy equivalent to practical instrumentalism, political realism and romantic utilitarianism. Consequently, they have favored literary works in the realistic tradition for their textual analyses, while eschewing a more imaginative genre like the American Romance. My contention is that James's version of pragmatism is a future oriented pluralism which is unable to dispense with the power of imagination and the talent for seeing unforeseen possibilities inherent in nature and culture. James's pragmatism is in tune with the American Romance in that it savours the attractions of alternative possibilities created by the genre in which the imaginary world is imbued with the actual one. The pragmatic impulse in Moby-Dick finds its finest expression in the words and acts of Ishmael. Through this protean narrator, Melville renders the text of Moby-Dick symbolic, fragmentary and thereby pluralistic in its meaning. With his rhetoric of incompletion and by refraining from totalizing what he experiences, Ishmael shuns finality in truth and entices the reader to join his intellectual journey with a non-foundational notion of truth and meaning in view. Ishmael also envisages pragmatists' beliefs that experience is fluid in nature and the universe is in a constant state of becoming. Yet Ishmael as the narrator of Moby-Dick is more functional than foundational.

• Korean Journal of Food Science and Technology
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• v.54 no.2
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• pp.141-146
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• 2022

This study investigated the quality characteristics and antioxidant activities of preserved jams prepared by mixing various ratios of aronia and sugar. To analyze the quality characteristics, the total sugar, pH, moisture, maximum stress, hardness, total phenolics, 1,1-diphenyl-2-picrylhydrazyl (DPPH), trolox-equivalent antioxidant capacity (TEAC), ferric reducing antioxidant power (FRAP), oxygen radical absorbance capacity (ORAC), and sensory characteristics of the preserved jams were measured. Lower aronia contents resulted in higher total sugar content, hardness, and strength, as well as lower moisture, total phenolic content, and DPPH, TEAC, FRAP, and ORAC values. In terms of the sensory characteristics, an aronia content of 30%, which was determined to have strong sweetness and texture, resulted in the lowest overall acceptability. In contrast, the highest preference was shown to an aronia content of 40%. In this study, quality characteristics and antioxidant activity experiments were conducted based on various ratios of aronia and sugar. The results are expected to be used as preliminary data for developing products that use domestic aronia.

• Nuclear Engineering and Technology
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• v.54 no.6
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• pp.2311-2320
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• 2022

The main outcomes of the experiments H2P6 performed in the thermal-hydraulics large-scale PANDA facility at PSI in the frame of the OECD/NEA HYMERES-2 project are presented in this article. The experiments of the H2P6 series consists of two PANDA tests characterized by the activation of three (H2P6_1) or one (H2P6_2) cooler(s) in an initially stratified and pressurized containment atmosphere. The initial stratification is defined by a helium-rich region located in the upper part of the vessel and a steam/air atmosphere in the lower part. The activation of the cooler(s) results i) in the condensation of the steam in the vicinity of the cooler(s), ii) the corresponding activation of large scale natural circulation currents in the vessel atmosphere, with the result of iii) the re-distribution and mixing of the Helium stratification initially located in the upper half of the vessel and iv) the continuous pressure decay. The initial helium layer represents hydrogen generated in a postulated severe accident. The main question to be answered by the experiments is whether or not the interaction of the different, localized cooler units would be important for the application of numerical methods. The paper describes the initial and boundary conditions and the experimental results of the H2P6 series with the suggestion of simple scaling laws for both experiments in terms of i) the temperature difference(s) across the cooler(s), ii) the transient steam and helium content and iii) the pressure decay in the vessel. The outcomes of this scaling indicate that the interaction between separate, closely localized units does not play a prominent role for the present experiments. It is therefore reasonable to model several units as one large component with equivalent heat transfer area and total water flow rate.

• Journal of Microbiology and Biotechnology
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• v.31 no.7
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• pp.990-998
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• 2021

Melanin is a natural skin pigment produced by specialized cells called melanocytes via a multistage biochemical pathway known as melanogenesis, involving the oxidation and polymerization of tyrosine. Melanogenesis is initiated upon exposure to ultraviolet (UV) radiation, causing the skin to darken, which protects skin cells from UVB radiation damage. However, the abnormal accumulation of melanin may lead to the development of certain skin diseases, including skin cancer. In this study, the antioxidant and antimelanogenic activities of the cell-free supernatant (CFS) of twenty strains were evaluated. Based on the results of 60% 2,2-diphenyl-1-picrylhydrazyl scavenging activity, 21% 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) scavenging capacity, and a 50% ascorbic acid equivalent ferric reducing antioxidant power value, Limosilactobacillus fermentum JNU532 was selected as the strain with the highest antioxidant potential. No cytotoxicity was observed in cells treated with the CFS of L. fermentum JNU532. Tyrosinase activity was reduced by 16.7% in CFS-treated B16F10 cells (but not in the cell-free system), with >23.2% reduction in melanin content upon treatment with the L. fermentum JNU532-derived CFS. The inhibitory effect of the L. fermentum JNU532-derived CFS on B16F10 cell melanogenesis pathways was investigated using quantitative reverse transcription polymerase chain reaction and western blotting. The inhibitory effects of the L. fermentum JNU532-derived CFS were mediated by inhibiting the transcription of TYR, TRP-1, TRP-2, and MITF and the protein expression of TYR, TRP-1, TRP-2, and MITF. Therefore, L. fermentum JNU532 may be considered a potentially useful, natural depigmentation agent.

• Journal of the Semiconductor & Display Technology
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• v.21 no.3
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• pp.80-86
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• 2022

In this paper, the optimal design and circuit simulation verification results of an LLC resonant half-bridge dc-dc converter using a steady-state model with internal loss resistance are reported. Above all, the input/output voltage gain and frequency characteristic equations in the steady-state were derived by reflecting the internal loss resistance in the equivalent circuit. Based on the results, an LLC resonant half-bridge dc-dc converter with an input voltage of 360-420V, an output voltage of 54V, and a maximum power of 3kW was designed, and to verify the design, the PSIM circuit simulation was executed to compare and analyze the result. In particular, the operating range of the converter could be drawn from the frequency characteristic graph of the voltage gain, and when the converter was operated under light and maximum load conditions, it was confirmed that similar results were obtained by comparing simulation results and calculation results in the switching frequency characteristic graph. In addition, the change of the switching frequency with respect to the load current at each input voltage was compared with the calculated value and the simulation result. As a result, it was possible to confirm the usefulness of the analysis result reflecting the internal loss resistance proposed in this paper and the process of the optimal design.

• Advances in nano research
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• v.14 no.3
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• pp.211-224
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• 2023

This work presents a modified analytical model for the bending behavior of axially functionally graded (AFG) carbon nanotubes reinforced composite (CNTRC) nanobeams. New higher order shear deformation beam theory is exploited to satisfy parabolic variation of shear through thickness direction and zero shears at the bottom and top surfaces.A Modified continuum nonlocal strain gradient theoryis employed to include the microstructure and the geometrical nano-size length scales. The extended rule of the mixture and the molecular dynamics simulations are exploited to evaluate the equivalent mechanical properties of FG-CNTRC beams. Carbon nanotubes reinforcements are distributed axially through the beam length direction with a new power graded function with two parameters. The equilibrium equations are derived with associated nonclassical boundary conditions, and Navier's procedure are used to solve the obtained differential equation and get the response of nanobeam under uniform, linear, or sinusoidal mechanical loadings. Numerical results are carried out to investigate the impact of inhomogeneity parameters, geometrical parameters, loadings type, nonlocal and length scale parameters on deflections and stresses of the AFG CNTRC nanobeams. The proposed model can be used in the design and analysis of MEMS and NEMS systems fabricated from carbon nanotubes reinforced composite nanobeam.

• Progress in Superconductivity and Cryogenics
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• v.11 no.1
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• pp.49-54
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• 2009

This paper presents the numerical simulation results on the moving type electrodynamic suspension (EDS) simulator and static type EDS simulator using high-Tc superconducting (HTS) levitation magnet. The levitation force of the EDS system is formed by the reaction between the moving magnet and the fixed ground conductor. The possible two ways to simulate the EDS system were simulated in this paper by using finite element method (FEM). The first way was the moving type simulator which consists of the fixed HTS magnet and the moving ground conductor. The second way was the static type simulator which consists of the fixed magnet, the fixed ground conductor and the ac current supply system. To verify the characteristics of high speed EDS system with the moving type simulator heavy, large and fast moving ground conductor is needed. The static type simulator can get the characteristics of the high speed EDS system by applying equivalent ac current to velocity, therefore it does not need large moving part. The static type EDS simulator, which can consist of an HTS magnet, the fixed ground conductor(s), an AC power supply and the measuring devices, also test the effect of the shape of the ground conductor easily. The plate type ground conductor made stronger levitation force than ring type ground conductor. Although the outer diameter 335 mm ring type ground conductor (Ring3) was larger than the outer diameter 235 mm ground conductor (Ring2), the levitation force by Ring2 was stronger than that by Ring3. From the calculation results on this paper, the consideration of the magnetic flux distribution according to the levitation height should be included in the process of the ground conductor design.

• Composites Research
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• v.20 no.3
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• pp.50-54
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• 2007

The Ionic Polymer Metal Composite (IPMC), an electro-active polymer, has many advantages including bending actuation, low weight, low power consumption, and flexibility. These advantages coincide with the requirements of a bio-related application. Thus, IPMC is promising materials for bio-mimetic actuator and sensor applications. Before applying IPMC to actual application, basic mechanical properties of IPMC should be studied in order to utilize IPMC for practical uses. Therefore, IPMCs are fabricated to investigate the mechanical characteristics. Nafion is used as a base ionic polymer. Mason samples cast with various thicknesses are used to test the thickness effects of IPMC. Subsequently, IPMC is fabricated using the chemical reduction method. The deformation, blocking force and frequency response of the IPMC actuator are important properties. In this present study, the performances of the IPMC actuators, including the deformation, blocking force and natural frequency, are then obtained according to only the input voltage and IPMC dimensions. Finally, the empirical performance model and the equivalent stiffness model of the IPMC actuator are established using experiments results.

• Journal of Information Science Theory and Practice
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• v.10 no.spc
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• pp.56-65
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• 2022

Korea Institute of Science and Technology Information (KISTI) is a Worldwide LHC Computing Grid (WLCG) Tier-1 center mandated to preserve raw data produced from A Large Ion Collider Experiment (ALICE) experiment using the world's largest particle accelerator, the Large Hadron Collider (LHC) at European Organization for Nuclear Research (CERN). Physical medium used widely for long-term data preservation is tape, thanks to its reliability and least price per capacity compared to other media such as optical disk, hard disk, and solid-state disk. However, decreasing numbers of manufacturers for both tape drives and cartridges, and patent disputes among them escalated risk of market. As alternative to tape-based data preservation strategy, we proposed disk-only erasure-coded archival storage system, Custodial Disk Storage (CDS), powered by Exascale Open Storage (EOS), an open-source storage management software developed by CERN. CDS system consists of 18 high density Just-Bunch-Of-Disks (JBOD) enclosures attached to 9 servers through 12 Gbps Serial Attached SCSI (SAS) Host Bus Adapter (HBA) interfaces via multiple paths for redundancy and multiplexing. For data protection, we introduced Reed-Solomon (RS) (16, 4) Erasure Coding (EC) layout, where the number of data and parity blocks are 12 and 4 respectively, which gives the annual data loss probability equivalent to 5×10^-14. In this paper, we discuss CDS system design based on JBOD products, performance limitations, and data protection strategy accommodating EOS EC implementation. We present CDS operations for ALICE experiment and long-term power consumption measurement.