• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5037-5042
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• 2012

Background: Tobacco contains agents which generate various potent DNA adducts that can cause gene mutations. Production of DNA adducts may be neutralized by glutathione S transferase (GST) along with other phase I and phase II enzyme systems. The existence of null type of GST among the population increases the susceptibility to various disorders and diseases. The present study focuses on the impact of high tobacco usage and possible null type mutation in GST loci. Methods: Genotypes of GST were detected by multiplex polymerase chain reaction in unrelated 504 volunteers of high tobacco using natives of Gujarat. Allelic frequencies were calculated using Statistical Package for Social Studies-16 software. Hardy Weinberg Equilibrium (HWE) was calculated using Chi square test. Two sided Fisher's significance test was used to compare allelic frequencies of different populations. Results: The frequency of homozygous null genotype of GSTM1 and GSTT1 were 20% (95% CI 16.7-23.9) and 35.5% (95% CI 31.4-39.9) respectively. The GSTM1 and GSTT1 null allele frequency distribution in the Gujarat population was significantly deviating from HWE. GSTT1 null frequency of Gujaratians was significantly higher and different to all reported low tobacco using Indian ethnics, while GSTM1 was not differing significantly. Conclusion: Tobacco usage significantly influences the rate of mutation and frequency of GSTT1 and M1 null types among the habituates. The rate of mutation in GSTT1 loci was an undeviating response to the dose of tobacco usage among the population. This mutational impact of tobacco on GSTT1 postulates the possible gene - environment interaction and selection of null genotype among the subjects to prone them under susceptible status for various cancers and even worst to cure the population with GSTT1 dependent drugs.

• Journal of Korean Society on Water Environment
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• v.22 no.2
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• pp.328-332
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• 2006

Fe(III)-impregnated activated carbon (Fe-AC) was applied in the treatment of synthetic wastewater containing Cu(II). To investigate the stability of Fe-AC at acidic condition, dissolution of Fe was studied with a variation of solution pH ranging from 2 to 4. Fe-AC was unstable at pH 2, showing a gradual increase of the dissoluted Fe as reaction time increased, while negligible amount of Fe was dissoluted above pH 3. This stability test suggests the applicability of Fe-AC in the treatment of wastewater above pH 3. Adsorption capacity of Cu(II) onto activated carbon (AC) and Fe-AC was investigated in a batch and a column test. In the adsorption kinetics, rapid adsorption of Cu(II) onto AC and Fe-AC was noted at initial reaction time and then reached a near complete equilibrium after 6 hrs. Adsorption trends of Cu(II) onto AC and Fe-AC were similar, showing an increased Cu(II) adsorption at higher pH. Compared with AC, Fe-AC showed a greater Cu(II) adsorption over the entire pH range studied in this research. From the adsorption isotherm obtained with variation of the concentration of Cu(II), the maximum adsorption capacity was identified as 61,700 mg/kg.

• Transactions of the Korean Society of Automotive Engineers
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• v.23 no.2
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• pp.199-207
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• 2015

Solid materials of ammonia sources with SCR have been considered for the application of lean NOx reduction in automobile industry, to overcome complex problems of liquid urea based SCR. These solid materials produce ammonia gas directly with proper heating and can be packaged by compact size, because of high volumetric ammonia density. Among ammonium salts and metal ammine chlorides, calcium ammine chloride was focused on this paper due to low decomposition temperature. In order to make calcium ammine chloride in lab-scale, simple reactor and glove box was designed and built with ammonium gas tank, regulator, and sensors. Basic test conditions of charging ammonia gas to anhydrous calcium chloride are chosen from equilibrium vapor pressure by Van't Hoff plot based on thermodynamic properties of materials. Synthetic method of calcium ammine chloride were studied for different durations, temperatures, and pressures with proper ammonia gas charged, as a respect of ammonia gas adsorption rate(%) from simple weight calculations which were confirmed by IC. Also, lab-made calcium ammine chloride were analyzed by TGA and DSC to clarify decomposition step in the equations of chemical reaction. To understand material characteristics for lab-made calcium ammine chloride, DA, XRD and FT-IR analysis were performed with published data of literature. From analytical results, water content in lab-made calcium ammine chloride can be discovered and new test procedures of water removal were proposed.

• The Journal of Engineering Geology
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• v.17 no.4
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• pp.545-554
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• 2007

Landslides is mainly induced by a heavy rainfall, earthquake ground motion, and some other factors like soil mechanics, morphological-geological factors etc. Since the starting point of the failure seemed to be originated at a construction site in the study, it is meaningful to find out the relationship between the landslide and the construction. For this study, the slope failure factor was examined carefully to see that the original natural slope had vulnerability and that the complex ground had unstability changed by construction. A field survey was conducted on the original ground surface and filled-up ground. A laboratory test was also conducted to determine the geomechanical properties of soil samples. 2D and 3D limit equilibrium analysis with changing groundwater level were conducted at the failure depth using a seismic refraction survey. The result shows that the factor of safety is similar stability under all condition, but unstable under saturated condition.

• Animal cells and systems
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• v.1 no.1
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• pp.123-128
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• 1997

The characteristics of allelic polymorphisms of the two (CA)n microsatellite (p599 and ㅅ599) markers spanning the long arm of chromosome 5 were studied in 52 DNA samples from unrelated inhabitants of Seoul (Korea) by using the polymerase chain reaction (PCR) to investigate differences in allele frequencies between Korean and Caucasian populations. The 6 alleles were observed for p599 (CA)n with a polymorphism informative content (PIC) value of 0.71 and 9 alleles for ㅅ599 (CA)n with a PIC value of 0.82. The observed heterozygote frequencies of the loci were estimated to 0.730 and 0.846, respectively. Several allele frequencies of two loci showed significant differences between Korean and Caucasian populations. Genotype data from the two loci were consistent with the Hardy-Weinberg equilibrium by x2 test. Linkage disequilibrium between p599 (CA)n and ㅅ599 (CA)n loci was observed in x2 test between the observed and expected frequency of allelic association. The probability of matching calculated at each locus was 0.104 for p599 (CA)n and 0.043 for ㅅ599 (CA)n, respectively. These results demonstrate the need to determine populationspecific allele frequency distributions for polymorphic markers when performing genetic linkage studies in racially defined several populations.

• Korean Journal of Food Science and Technology
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• v.27 no.3
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• pp.324-328
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• 1995

The changes in the rheological properties of soybean curd upon the processing conditions were measured by the failure test, and analyzed by the stress-relaxation data. Soybean curd coagulated with $CaCl_2$ showed a higher failure stress value than other coagulants such as $MgCl_2,\;CaSO_4\;and\;Glucono-{\delta}-lactone$ (GDL), whereas addition of 0.3% $CaCl_2$ produced higher failure stress value than other concentrations $0.2{\sim}0.6%)$. Also, maximum failure stress of soybean curd was shown at the higher heating temperatures$(95^{\circ}C)$ and greater molding pressures, respectively. Initial and equilibrium stress at the stress relaxation curves showed the same tendency as those of failure test, and magnitude of elastic elements$(E_0,\;E_e)$ and viscous element$({\eta})$ were numerically expressed through simple Maxwell model analysis.

• Journal of the Mineralogical Society of Korea
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• v.11 no.2
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• pp.117-125
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• 1998

Crystallization behavior of platinum minerals within Pt-Sb-Bi bearing ore magmas and mineralogical properties of the existing minerals were investigated at 1,00$0^{\circ}C$ by synthetic experiment. High purity reagents were used as starting materials and silica tubings as containers. Reaction products were analysed by reflecting microscopy, X-ray diffraction, electron probe microanalysis, and micro-hardness test. Stable minerals at 1,00$0^{\circ}C$ are platinum, electron probe microanalysis, and micro-hardness test. Stable minerals at $1,000^{\circ}C$ are platinum, stump-flite (PtSb) and geversite (PtSb2). They are in equilibrium with liquid (ore magma). Platinum contains considerable amount of Sb of 7.5 at.%, whereas Bi only up to 0.9 at.%. Pure stumpflite is hexagonal with space group P63/mmc, and unit cell parameters are a=4.1318(6), c=5.483(1)$\AA$. VHN50=417(2)$\AA$. Geversite has cubic structure with space group Pa3. Cell parameters are a=6.4373(2)$\AA$ and Vicker hardness values VHN50=663.5 (566~766). Both stumpflite and geversite show solid solution and their end-members are Pt48.8Sb40.7-Bi10.5, and Pt33.7-Sb59.8Bi6.5, respectively. Although stumpflite (m.p. $1,043^{\circ}C$) and unnamed PtBi (m.p. 7$65^{\circ}C$) do not form a complete solid solution at $1,000^{\circ}C$, they are known, at $600^{\circ}C$, to form a continuous solid solution. Geversit (m.p. $1,226^{\circ}C$) also forms complete solid solution with insizwaite (m.p. $660^{\circ}C$). Unit cell dimensions of the minerals above increases with the amount of Bi substituting for Sb.

• Preventive Nutrition and Food Science
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• v.16 no.3
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• pp.267-271
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• 2011

Static Headspace Gas Chromatographic analysis was used to study the partitioning behavior of five organic printing ink solvents between chocolate cookie/air systems. Three cookie sample formulations varied with respect to chocolate type and overall percentage of constituents. Major considerations involved differences in fat content and type and resulting variability in chemical and physical structure. Each of the solvents studied (ethyl acetate, hexane, isopropanol, methyl ethyl ketone, toluene) represents a general class of printing ink solvents based on predominate functional group. Values of the partitioning coefficient (Kp) were determined at equilibrium using measured quantities of both solvent and cookie sample in closed systems at temperature of 25, 35, and $45^{\circ}C$. In each of the three cookies at the three test temperatures, toluene always exhibited the greatest value of partitioning to cookie and hexane always exhibited the least. Results also showed that the partitioning behavior of solvents is generally inversely related to temperature and that solvent affinity, though constant for a particular cookie type over all test temperatures, varies significantly among the three cookie types. The preference of each of the five solvents for each cookie sample was also found to vary with temperature. No correlation was found between the extent of partitioning and cookie formulation or physical characteristic of solvent. The Hildebrand parameter, related to ${\Delta}Hmix$ (heat of mixing), may be used to describe differences in partitioning based on the overall potential of a solvent/cookie interaction to occur. The potential for interaction is dependent upon the chemical structure of the cookie sample and thus the availability of 'active-sites' required for a given solvent.

• The Korean Journal of Rehabilitation Nursing
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• v.4 no.1
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• pp.7-19
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• 2001

The Objectives of this research is to determine the effect of aerobic exercise program on health status and physical fitness in patients after the stem cell transplantation. This research design is one-group pretest-post test design. Sixteen subjects were selected from one university hospital in Seoul for the study, they was carried out aerobic exercise three to five times a week for 12 weeks. The period of data collection was from February to July, 2000. The collected data was analysed by descriptive analysis, paired t-test, content analysis SAS program was used for the statistical analysis. The results are as follows : 1. There was a significant improvement in the Physical functioning, Vitality and Reported change (t=2.39, p=0.03; t=2.35, p=0.03; t=2.58, p=0.02) but no change was observed in the Role physical, General health perception, Bodily pain, Social functioning, Role emotional and Mental health. 2. There was a significant improvement in the physical fitness (higher VO2 max, t=2.43, p=0.02; lower systolic pressure, t=-4.09, p=0.001; lower diastolic pressure, t=-3.43, p=0.002; lower pulse rate, t=-3.43, p=0.004; higher muscle sustaining power, t=2.79, p=0.015; higher muscle power, t=5.18 p=0.000; higher power of beginning, t=5.55, p=0.001; higher the sense of equilibrium, t=3.57, p=0.003; higher Hemoglobin, t=5.92, p=0.000; higher Hematocrit, t=5.38, p=0.000). Therefore, this study will provide a theoretical back ground for patients after stem cell transplantation to understand the importance of physical exercise and maintain physical exercise; and for other researches to refer to the results for exercise protocol of rehabilitation program.

• Journal of Korean Association for Spatial Structures
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• v.7 no.2 s.24
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• pp.115-124
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• 2007

The initial shape is arrived at by a self-formation process, which accomplishes a form in the natural world, or is determined analytically by considering the equilibrium of initial stress only. Therefore, the self-formation process, which accomplishes a form in the natural world is grasped and the types of modeling techniques available to find the shapes of soft structures are well investigated and classified. To establish a form-finding modeling techniques, the models of string, soap film, fabric, rubber, plaster, and etc. are used. These modeling techniques can be used as a method of understanding the characteristics of structures when the material of model shows similar characteristics. Generally, the model test confirms the structure based on numerical analysis, at the same time it is important preceding process to develop such a program. With the above process, the relationship between model test and numerical analysis becomes a feedback process. Therefore, in this study, two examples which have been accomplished from such a technique are investigated and considered according to modeling process.