• Journal of Korean Society for Atmospheric Environment
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• v.11 no.1
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• pp.45-56
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• 1995

We considered that characteristics of surface ozone continuous and important meteorological parameters from the data measured 7 air quality continuous monitoring stations during 2 years (1990, 1993) in pusan. The diurnal ozone variation showed a primary peak near 1500LST and a secondary peak of the DP(double peaked) pattern. The episode day was defined when an ozone peak higher than 60 ppb was observed at least one station. The frequency of episode day was 100 (298 hours, 69 days). The frequency of the episode day was higher at Meongryundong and Daeyeondong than other sites and highest in August under control of pacific subtropical high. The high temporatant meteorological parameters accompanying the high episode days. The favorable synoptic environment accompanying ozone episode was distributed to 7 different pattern. These pattern can be taken as a nesessary but not an absolute indicator for predicting the occerrence of an episode.

• Korean Journal of Biological Psychiatry
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• v.16 no.3
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• pp.205-211
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• 2009

Objectives : Serum and plasma BDNF levels have been shown to be decreased in patients with mood disorder such as major depressive disorder and bipolar disorder. We investigated whether platelet BDNF levels would be lower in patients with acute bipolar manic episode compared with those of normal controls. Methods : BDNF levels were examined in platelet-rich plasma(PRP) and platelet-poor plasma(PPP) in 20 healthy controls and 20 hospitalized patients who were diagnosed as bipolar I disorder, most recent episode manic using a Structured Clinical Interview for DSM-IV. And severity of manic symptoms was measured using Young Mania Rating Scale(YMRS). Platelet BDNF level was calculated by subtracting PPP BDNF from PRP BDNF level, and dividing the result by the total platelet count, and it was expressed as pg/$10^6$ platelet. Results : Platelet BDNF levels were significantly lower in patients with acute bipolar manic episode(4.55${\pm}$3.36pg/$10^6$ platelet) than in normal controls(6.84${\pm}$2.32pg/$10^6$ platelet)(p=0.008). However we failed to reveal the significant negative correlation between platelet BDNF levels and YMRS scores in patients with acute bipolar episode. Conclusion : Our finding suggests that there is a decrease in the platelet BDNF of patients with acute bipolar manic episode.

• The Korean Journal of Applied Statistics
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• v.20 no.3
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• pp.449-458
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• 2007

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in person's mood, energy, and ability to function. Compared with manic episode, the depression episode causes more serious results such as restless, loss of interest or pleasure, or thoughts of death or suicide and the cure rate of depression episode is lower than that of manic episode. Furthermore, a long term use of antidepressants in bipolar patients may result in manic episode. Our interest is to investigate the effect of antidepressant on switch of moods of bipolar patients and to estimate the transition probabilities of switch between moods, depression and (hypo) manic. In this study, three approaches are applied in terms of multi state model. Parametric model is applied using left censoring data and nonparametric model is implemented under illness-death model with counting process. In order to estimate the effect of covariates, a multiplicative model is used. These all methods have similar results.

• Pediatric Infection and Vaccine
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• v.15 no.2
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• pp.188-194
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• 2008

Purpose : The purpose of this study is to investigate the clinical characteristics of recurrent Kawasaki disease (KD). Methods : From January 2004 to December 2007, the medical records of 20 children with recurrent KD in Severance Children's Hospital were retrospectively reviewed. The clinical characteristics, laboratory findings, treatment and complications of these patients were compared between the initial episode and the second episode. Results : At the initial episode of the recurrent KD group, the gender ratio was 1.2:1 (male:female) and the mean age was $37.2{\pm}19.9$ months. The interval between the two episodes in the recurrent KD group was 3.3 months. The febrile period before admission was shorter for the second episode (P=0.034). The skin rash was less developed in the second episode. But there were no differences in the laboratory results and complications between the initial episode and the second episode. Three patients (15%) among those with a second episode failed to respond to the initial intravenous immunoglubulin treatment. On comparison between the initial episodes of the recurrent group and the nonrecurrent group, the erythrocyte sedimentation rate was higher in the first episode of the recurrent KD group. Conclusions : For recurrent KD, it tends to present more atypical features than the KD that occurs for the first time. Physicians should consider these characteristics when making the diagnosis and treating recurrent KD.

• Journal of Korean Society for Atmospheric Environment
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• v.30 no.5
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• pp.434-448
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• 2014

The aerosol characteristics between haze episode and Asian dust event were identified in January and March, 2013 in Gwang-ju of Korea to investigate the metal elements, ionic concentrations and carbonaceous particles of $PM_{2.5}$ and $PM_{10}$. In the haze episode, the concentrations were increased 1~3.2 times of ionic species and 1.6~2.7 of metal elements. Especially, the concentration of $NO{_3}{^-}$, $SO{_4}{^2-}$ and $NH{_4}{^+}$ consists of 50 percent in ionic species during haze episode that was higher than Asian dust event. This suggests that secondary aerosols from anthropogenic air pollution were mainly contributed by haze episode. During the Asian dust event, increase of metal concentrations was higher than haze episode because of remarkable increase of Ti, K and Fe originated from soil. The concentrations of carbonaceous particles were increased 2.5 times during haze episode, and 2.4 times of OC and 2.1 times of EC during Asian dust event in $PM_{2.5}$. However, these aerosol mass concentration does not affect the OC/EC ratio. The average equivalence ratios of cations/anions in $PM_{2.5}$ were 0.99 in haze episodes and 0.94 during non-event day. The neutralization factor of $NH_3$ was higher than that of $CaCO_3$. Futhermore, $NH{_4}{^+}$ aerosol was aged due to atmospheric stagnation that might be affected by the haze episode.

• Journal of Environmental Science International
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• v.11 no.12
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• pp.1253-1259
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• 2002

This study analyzes the surface ozone, NO and $NO_2$ concentration data from 1997 to 1999 in Daegu. It investigates effect on precursor during high-ozone episode days. The high-ozone episode is defined when a daily maximum ozone concentration is higher than 100 ppb(ambient air quality standard of Korea) in at least one station among six air quality monitoring stations. The frequency of episodes is 13 days(33 hours). The frequency is the highest in May and September, and the area with the highest frequency is Nowondong and Manchondong. The average value of daily maximum ozone concentration with high ozone episode is 81.6 ppb, and that of 8-hour average ozone concentration is 58.6 ppb. It means that ozone pollution is continuous and wide-ranging in Daegu. The daily variation of NO, $NO_2$ and $O_3$ in high-ozone episodes are inversely proportional one another. Nowondong an industrial area, is affected by pollutants that are emitted from the primary sources, while Manchondong a residential area, is affected by the advection of $O_3$ or by the primary pollutants like VOCs.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.50 no.4
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• pp.201-207
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• 2001

This paper describes an automated detection algorithm of ST-T episodes using global curvature which can connect the isoelectric level in ECG and can eliminate not only the slope of ST segment, but also difference of the baseline and global curve. This above method of baseline correction is very faster than the classical baseline correction methods. The optimal values of parameters for baseline correction were found as the value having the highest detection rate of ST episode. The features as input of backpropagation Neural Network were extracted from the whole ST segment. The European ST-T database was used as training and test data. Finally, ST elevation, ST depression and normal ST were classified. The average ST episode sensitivity and predictivity were 85.42%, 80.29%, respectively. This result shows the high speed and reliability in ST episode detection. In conclusion, the proposed method showed the possibility in various applications for the Holter system.

• Journal of Environmental Science International
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• v.9 no.4
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• pp.295-302
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• 2000

This study was conducted to investigate the characteristics of surface ozone concentration and occurrence of high ozone concentration using hourly ozone, nitrogen dioxide and meteorological data for 1997~1998 in Pusan coastal area. Monthly mean ozone concentration was the highest at Dongsamdong in Spring(35.4ppb), at Kwangbokdong in Fall(25.1ppb) and the lowest Dongsamdong(22.2ppb) and Kwangbokdong(16.0ppb) in Winter. Relative standard deviation indicating clearness of observation site was 0.42 at Dongsamdong and 0.49 at Kwangbokdong that is similar to urban area. The diurnal variation of ozone concentration of Dongsamdong and Kwangbokdong showed maximum at 1500~1600LST and minimum 0700~0800LST that typical pattern of ozone concentration. In ozone episode period(Sept. 10~15, 1998), diurnal change of ozone concentration was very high, and ozone concentration was related to meteorological parameters such as temperature, relative humidity, wind speed, cloud amount and radiation on a horizontal surface. During the episode days peak ozone concentrations are much higher than the normal values, wind speeds are always lower, and solar radiation is high with the exception of the September episode.

• Journal of Environmental Impact Assessment
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• v.15 no.3
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• pp.193-206
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• 2006

Recently, high ozone episode occurred frequently in Korea. Moreover ozone episode occurred not only in the city but also in background area where local anthropogenic sources are not important. It analyzed frequency exceeding 100ppb ozone at air quality monitoring stations in Seoul and rural area during 1995-2004. This paper reports on the use of the Community Multiscale Air Quality (CMAQ) modelling system to predict hourly ozone levels. Domain resolutions of 30km, 10km, 3.333km (innermost) have been employed for this study. Summer periods in June 2004 have been simulated and the predicted results have been compared to data for metropolitan and rural air quality monitoring stations. The model performance has been evaluated with measured data through a range of statistical measures. Although, the CMAQ model reproduces the ozone temporal spatial trends it was not able to simulate the peak magnitudes consistently.

• Journal of Environmental Science International
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• v.16 no.8
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• pp.985-994
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• 2007

To investigate the effect of NOx and VOCs(volatile organic compounds) on the generation of high ozone episode, examined the hourly variations of ozone, NOx and VOCs concentrations, and calculated the ozone isopleth about maximum ozone concentrations using OZIPR which was presented by U. S. EPA at three sites in Busan. There was some difference by the sites, but decreasing VOCs concentration was effective for reduction of ozone at 22 July, the episode day of 2005. In the year 2006, the episode day was 8 August and the variations of NOx and VOCs concentration was little than variation of ozone. So it was estimated that the photochemical production of ozone was low than transportation of ozone. And the result of the OZIPR modeling was that decreasing VOCs concentration was effective for reduction of ozone.