• 제목/요약/키워드: epidemiologic methods

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악안면 기형 환자들의 발현 양상, 원인 요소 및 외과적 교정 방법에 관한 역학적연구 (A RETROSPECTIVE STUDY ON THE CLINICAL MANEFESTATIONS, ETIOLOGIC FACTORS OR SURGICAL CORRECTION METHODS OF THE MAXILLOFACIAL DEFORMITY PATIENTS)

  • 현충환;임창준
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제19권3호
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    • pp.233-242
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    • 1997
  • Recently the goal of orthognathic surgery has been focused on esthetic improvement of the patients. Also early corrective surgery was favorable selected by most of the oral and maxillofacial surgeons. We should consider the etiologic factor of the patient's dentofacial deformities when treatment is planned, because this is the major factor in estimating the predictability or stability of result. The more researches were carried on the etiologic factors of the dentofacical deformities, The more possibility of the early surgical correction will be increased. The authors analyzed about etiologic factors and epidemiologic studies of the forth patients who had received the orthognathic surgery. The analyzed results were as follows: 1. The predilection ration between male and female was 17:23, and 32 patients (80%) of 40 patients were aged twenties. 2. 26patients(65%) complained estetic problems as well as functional problems. 10 patients(25%) complained only esthetic problems, and 4 of 40 patients complained only functional problems. 3. Mandibular prognathism was found to be done most frequently(25, 39%). Facial asymmetry (13, 20%) and angle hypertrophy were found to be next in sequence. 4. Sagittal split ramus ostetomy was done most frequently(27, 35%). Lefort I osteotomy(13, 17%), angle reduction (12,16%), and genioplasty(11, 15%) were done also. 5. The number of the cases due to nonspecific etiologic factor was 22(55%), that of cases due to inhertied tendency was 12(30%), that of cases due to congenital anomaly was 3(7.5%), and that of cases due to trauma was 3(7.5%). 6. The number of patients who got only maxilliary surgery was 2(5%), that of patients who got only mandibular surgery was 23(57.5%), and that of patients who got simultaneous two jaw surgery was 15(37.5%).

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Examination History and Abnormal Thyroid and Breast Lesions According to Residential Distance from Nuclear Power Plants

  • Lim, Young-Khi
    • Journal of Radiation Protection and Research
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    • 제41권4호
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    • pp.402-408
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    • 2016
  • Background: Ascertainment bias are common in epidemiologic studies to assess the association between thyroid cancer risk and living near nuclear power plants because many thyroid cancers are diagnosed by chance through health examination. We surveyed the ultra sonography (USG) examination history and conducted thyroid and breast USG in residents living near nuclear power plants. Materials and Methods: The study population comprised 2,421 residents living near nuclear power plants in Korea. Information on demographic characteristics, including diagnostic examination history, was collected by interview using questionnaires. USG examination was conducted to evaluate the presence of thyroid nodules and breast lesion. Study participants were divided into 3 groups according to the distance of their respective villages from a nuclear power plant. The proportions of USG examination history and prevalence of thyroid nodules and breast lesions were compared between groups. Results and Discussion: Examination histories of thyroid USG were 23.1%, 13.7%, and 10.5% in men and 31.3%, 26.7%, 18.3% in women in the short, intermediate, and long distance groups, respectively. There were significant inverse associations between thyroid USG history and the distance from nuclear power plants (P for trend = 0.001 for men and 0.017 for women). However, there was no association between the distance of villages from nuclear power plants and prevalence of thyroid nodules. Conclusion: Our results suggest that there may be an ascertainment bias in population-based studies examining the harmful effects of NPPs examination and researchers should pay attention to ascertainment bias resulted from differential health examination. Correction for ascertainment bias, active follow-up and examination for all study population to remove differential health examination is needed.

서울시 미세먼지(PM10)와 초미세먼지(PM2.5)의 단기노출로 인한 사망영향 (Effects of Short-term Exposure to PM10 and PM2.5 on Mortality in Seoul)

  • 배현주
    • 한국환경보건학회지
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    • 제40권5호
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    • pp.346-354
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    • 2014
  • Objectives: Although a number of epidemiologic studies have examined the association between air pollution and mortality, data limitations have resulted in fewer studies of particulate matter with an aerodynamic diameter of ${\leq}2.5{\mu}m$ ($PM_{2.5}$). We conducted a time-series study of the acute effects of particulate matter with an aerodynamic diameter of ${\leq}10{\mu}m$($PM_{10}$) and $PM_{2.5}$ on the increased risk of death for all causes and cardiovascular mortality in Seoul, Korea from 2006 to 2010. Methods: We applied the generalized additive model (GAM) with penalized splines, adjusting for time, day of week, holiday, temperature, and relative humidity in order to investigate the association between risk of mortality and particulate matter. Results: We found that $PM_{10}$ and $PM_{2.5}$ were associated with an increased risk of mortality for all causes and of cardiovascular mortality in Seoul. A $10{\mu}g/m^3$ increase in the concentration of $PM_{10}$ corresponded to 0.44% (95% Confidence Interval [CI]: 0.25-0.63%), and 0.95% (95% CI: 0.16-1.73%) increase of all causes and of cardiovascular mortality. A $10{\mu}g/m^3$ increase in the concentration of $PM_{2.5}$ corresponded to 0.76% (95% CI: 0.40-1.12%), and 1.63% (95% CI: 0.89-2.37%) increase of all causes and cardiovascular mortality. Conclusion: We conclude that $PM_{10}$ and $PM_{2.5}$ have an adverse effect on population health and that this strengthens the rationale for further limiting levels of $PM_{10}$ and $PM_{2.5}$ in Seoul.

직무스트레스 영역의 중복과 우울 및 자살사고 사이의 관계 (Associations of Overlapped Job Stress Components with Depressive Symptoms and Suicidal Idea)

  • 정찬현;임세원;신동원;오강섭;신영철
    • 대한불안의학회지
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    • 제13권1호
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    • pp.32-38
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    • 2017
  • Objective : Several recent studies determined the associations of job stress with depression and suicidal idea, but the association between the number of job stress components and depression remains unclear. In the present study, we investigated the associations of the number of components of job stress with depression and suicidal idea. Methods : We studied 194,226 participants who attended employee health screenings from January to December, 2014, and completely answered all the questionnaires, including the short form of Korean Occupational Stress Scale (KOSS), the Center for Epidemiologic Study-Depression (CES-D) and suicidal idea. The presence of clinical depressive symptoms was defined as a CES-D score of ${\geq}21$. The subjects in the highest quartile of each subscale of KOSS were considered as suffering from each component of job stress. Chisquare tests, t-tests and logistic regressions were performed to compare study outcomes between groups. Results : When we included all seven components of job stress, there was no significant association of the number of the components with depressive symptoms, or suicidal idea. However, the prevalence of depressive symptoms and suicidal idea was increased only in three occupational stress subscales including job demand, job insecurity and occupational climate. When we analyzed only these 3 components of job stress, the number of job stress subscales was significantly associated with depressive symptoms and suicidal idea, even after adjustment for sex and age. Conclusion : The number of components of occupational stress was associated with depressive symptoms and suicidal idea, only in the related components.

한국 직장인의 문제성 음주와 관련된 직무 스트레스 요인 (Job Stress Associated with Problematic Alcohol Drinking in Korean Employees)

  • 이다은;임세원;신동원;오강섭;신영철
    • 대한불안의학회지
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    • 제13권1호
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    • pp.39-45
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    • 2017
  • Objective : Korean employees tend to release their stress by alcohol drinking. This study aimed to investigate the association between job stress and problematic drinking in Korean employees. Methods : The study participants were 72,119 employees who attended health screenings and responded to the Alcohol Use Disorder Identification Test-Korea (AUDIT-K), Korean Occupational Stress Scale-Short Form (KOSS-SF), Center for Epidemiologic Study-Depression (CES-D), Beck Anxiety Inventory (BAI) and questionnaire on suicidal ideation and sociodemographic characteristics. We investigated the sociodemographic and clinical characteristics of the problematic drinking group ($AUIDT-K{\geq}12$) and used binary logistic regression to determine the impact of job stress on problematic drinking. Results : Age, gender, marital status, education year, sleep duration, obesity, smoking, suicidal ideation, and depression and anxiety showed significant differences between the problematic drinking group and normal group. Among the various kinds of job stresses, job insecurity and lack of reward were associated with problematic drinking. Conclusion : The result of this study suggested that certain kinds of job stress might be associated with problematic drinking in Korean employees.

Cases Series of Malignant Lymphohematopoietic Disorder in Korean Semiconductor Industry

  • Kim, Eun-A;Lee, Hye-Eun;Ryu, Hyung-Woo;Park, Seung-Hyun;Kang, Seong-Kyu
    • Safety and Health at Work
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    • 제2권2호
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    • pp.122-134
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    • 2011
  • Objectives: Seven cases of malignant lymphohematopoietic (LHP) disorder were claimed to have developed from occupational exposure at two plants of a semiconductor company from 2007 to 2010. This study evaluated the possibility of exposure to carcinogenic agents for the cases. Methods: Clinical courses were reviewed with assessing possible exposure to carcinogenic agents related to LHP cancers. Chemicals used at six major semiconductor companies in Korea were reviewed. Airborne monitoring for chemicals, including benzene, was conducted and the ionizing radiation dose was measured from 2008 to 2010. Results: The latency of seven cases (five leukemiae, a Non-Hodgkin's lymphoma, and an aplastic anemia) ranged from 16 months to 15 years and 5 months. Most chemical measurements were at levels of less than 10% of the Korean Occupational Exposure Limit value. No carcinogens related to LHP cancers were used or detected. Complete-shielded radiation-generating devices were used, but the ionizing radiation doses were 0.20-0.22 uSv/hr (background level: 0.21 ${\mu}Sv/hr$). Airborne benzene was detected at 0.31 ppb when the detection limit was lowered as low as possible. Ethylene oxide and formaldehyde were not found in the cases' processes, while these two were determined to be among the 263 chemicals in the list that was used at the six semiconductor companies at levels lower than 0.1%. Exposures occurring before 2002 could not be assessed because of the lack of information. Conclusion: Considering the possibility of exposure to carcinogenic agents, we could not find any convincing evidence for occupational exposure in all investigated cases. However, further study is needed because the semiconductor industry is a newly developing one.

서울지역 대기오염이 천식에 미치는 급성영향: 연구대상의 특성에 따른 비교 (Effects of Air Pollution on Asthma in Seoul: Comparisons across Subject Characteristics)

  • 김선영;김재용;김호
    • Journal of Preventive Medicine and Public Health
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    • 제39권4호
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    • pp.309-316
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    • 2006
  • Objectives: Korean epidemiological studies have used reduced samples according to the subject's characteristics, such as the health services provided, the historical note with asthma, and age, to examine the acute effect of air pollution on asthma using the Korean National Health Insurance records. However, there have been few studies on whether the effects shown in these reduced samples are different from those of all samples. This study compared the effects of air pollution on asthma attacks in three reduced samples with those of entire samples. Methods: The air pollution data for $PM_{10},\;CO,\;SO_2,\;NO_2,\;and\;O_3$, and weather conditions including temperature, relative humidity, and air pressure in Seoul, 2002, were obtained from outdoor monitoring stations in Seoul. The emergency hospital visits with an asthma attack in Seoul, 2002 were extracted from the Korean National Health Insurance records. From these, the reduced samples were created by health service, historical notes with asthma, and age. A case-crossover design was adopted and the acute effects of air pollution on asthma were estimated after adjusting for weather, time trend, and seasonality. The model was applied to each reduced sample and the entire sample. Results: With respect to the health service, the effects on outpatients were similar to those for the total sample but were different for inpatients. These similar effect sizes were also observed in the reduced samples according to the historical note with asthma and age. The relative risks of $PM_{10},\;CO,\;SO_2,\;NO_2,\;and\;O_3$, among the reduced and entire samples were 1.03, 1.04-1.05, 1.02-1.03, 1.04-1.06, and 1.10-1.17, respectively. Conclusions: There was no clear evidence to show a difference between the reduced samples and the entire samples.

정신증상 자가평가를 위한 스마트폰 어플리케이션의 활용 (Use of Mobile Mental Health Application for Self-Assessment of Psychiatric Symptoms)

  • 우정희;이상준;김은지;박종일;양종철;박태원;정상근
    • 대한불안의학회지
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    • 제14권2호
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    • pp.135-141
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    • 2018
  • Objective : This study evaluated the role of smartphone application in the self-assessment of three psychiatric symptoms: stress, depression, and suicidal ideation. Methods : A total of 5,646 respondents were evaluated with three scales (Perceived Stress Scale, PSS, Center for Epidemiologic Study for Depression, CES-D, Scale for Suicidal Ideation, SSI) via smartphone application 'mindscan'. We analyzed the sociodemographic variables, the levels of three symptoms, and the association between the scores on all three scales. Results : The mean total scores of PSS, CES-D, and SSI were 24.86, 35.15, and 18.03, respectively. Women showed significantly higher scores on PSS, CES-D, and SSI when compared with men. Younger users showed a significantly higher score on all three scales when compared with older users. The scores on all three scales were higher than in other studies with off-line surveys. The PSS was positively correlated with CES-D (r=0.690), and with SSI (r=0.367). The CES-D was positively correlated with SSI (r=0.540). Conclusions : A smartphone application for mental health based on three scales (PSS, CES-D, and SSI) is a relatively useful screening tool compared with off-line general population surveys. The association between the three scales reflects the relationship between the three psychiatric symptoms observed in clinical practice.

Descriptive Epidemiology of Acute Pyelonephritis in Korea, 2010-2014: Population-based Study

  • Kim, Bongyoung;Myung, Rangmi;Kim, Jieun;Lee, Myoung-jae;Pai, Hyunjoo
    • Journal of Korean Medical Science
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    • 제33권49호
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    • pp.310.1-310.11
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    • 2018
  • Background: Acute pyelonephritis (APN) is one of the most common community-acquired bacterial infections. Recent increases of antimicrobial resistance in urinary pathogens might have changed the other epidemiologic characteristics of APN. The objective of this study was to describe the current epidemiology of APN in Korea, using the entire population. Methods: From the claims database of the Health Insurance Review and Assessment Service in Korea, the patients with International Classification of Diseases, 10th Revision codes N10 (acute tubulo-interstitial nephritis) or N12 (tubulo-interstitial nephritis, neither acute nor chronic) as the primary discharge diagnosis during 2010-2014 were analyzed, with two or more claims during a 14-day period considered as a single episode. Results: The annual incidence rate of APN per 10,000 persons was 39.1 and was on the increase year to year (35.6 in 2010; 36.7 in 2011; 38.9 in 2012; 40.1 in 2013; 43.8 in 2014, P = 0.004). The increasing trend was observed in both inpatients (P = 0.014) and outpatients (P = 0.004); in both men (P = 0.042) and women (P = 0.003); and those aged under 55 years (P = 0.014) and 55 years or higher (P = 0.003). Eleven times more women were diagnosed and treated with APN than men (men vs. women, 6.5 vs. 71.3), and one of every 4.1 patients was hospitalized (inpatients vs. outpatients, 9.6 vs. 29.4). The recurrence rate was 15.8%, and the median duration from a sporadic episode (i.e., no episode in the preceding 12 months) to the first recurrence was 44 days. The recurrence probability increased with the number of previous recurrences. The average medical cost per inpatient episode was USD 1,144, which was 12.9 times higher than that per outpatient episode (USD 89). Conclusion: The epidemiology of APN in Korea has been changing with an increasing incidence rate.

The Association between Frequency of Social Contact and Frailty in Older People: Korean Frailty and Aging Cohort Study (KFACS)

  • Chon, Doukyoung;Lee, Yunhwan;Kim, Jinhee;Lee, Kyung-eun
    • Journal of Korean Medical Science
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    • 제33권51호
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    • pp.332.1-332.8
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    • 2018
  • Background: The trend of aging society is occurring globally, and with it, one of the health problems that is emerging is frailty. Efforts are being made to account for the increasing prevalence of frailty, and various modifiable factors are being considered in regards to frailty. Because social contact has shown beneficial effects in terms of health in previous studies, it is increasingly being considered in relation to frailty. The purpose of this study was to assess the association of different types of social contact with frailty status. Methods: A total of 1,200 Korean elders aged 70-84 years old were included in the study. Using Fried's Cardiovascular Health Study index to categorize the frailty status, the relationship between frailty status and frequency of contact (i.e., with family members, friends, or neighbors) was analyzed using multinomial logistic regression accounting for confounders. Results: Adjusting for all covariates, frequency of contact with friends was the most statistically significant. Less frequent contact was associated with a significantly higher odds of pre-frailty: monthly (odds ratio [OR], 2.02; 95% confidence interval [CI], 1.27-3.20), and rarely (OR, 1.87; 95% CI, 1.17-2.99), with daily contact group as reference. Also, those contacting friends monthly (OR, 5.04; 95% CI, 2.29-11.08) or rarely (OR, 3.23; 95% CI, 1.58-6.61) were more likely to be frail compared to the daily group. Conclusion: Frequency of social contact, especially with friends, is strongly associated with frailty.