• The Korea Journal of Herbology
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• v.34 no.6
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• pp.57-62
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• 2019

Objective : Gastritis is a major complication of gastrointestinal disease. Lonicera japonica is used in folk medicine to treat different diseases such as exopathogenic wind-heat, epidemic febrile diseases, sores, carbuncles and some infectious diseases. Therefore, this study examined the effects of Lonicera japonica water extract (LJE) on HCl/ethano-linduced acute gastric ulceration and anti-oxidants properties. Methods : LC-ESI-IT-TOF MS was employed for rapid identification of major compound from LJE. The antioxidant activities were evaluated through total polyphenol and flavonoid contents and radical scavenging assays and superoxide dismutase (SOD)-like activity. SD rats were randomly divided into five different groups including the normal group, ulcer group, positive group (20 kg/mg of omeprazole, ip), and experimental groups (100 kg/mg and 500 kg/mg of LJE, ip). Results : 4,5-Dicaffeoyl quinic acid, loganic acid, secologanic acid, sweroside, loganin, vogeloside were identified based on the detection of the molecular ion with those of literature data. The LJE was possessed free radical scavenging activities such as DPPH (IC₅₀=189.7 ㎍/㎖), ABTS (IC₅₀=164.5 ㎍/㎖), and SOD-like activity (IC₅₀=405.02 ㎍/㎖). Macroscopic and histological analyses showed LJE treated group were significantly reduced to an extent that it allowed leukocytes penetration of the gastric walls compared with the ulcer group. In addition, an ulcer inhibition rate and prostaglandin E₂ levels were increased in rats treated with LJE. Conclusion : The present study has demonstrated the antioxidantive and gastroprotective effect of LJE, these findings suggested that LJE has the potential for use in treatment of gastric disorders.

• Science of Emotion and Sensibility
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• v.24 no.4
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• pp.39-52
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• 2021

This study aims to investigate the effect of the coronavirus disease 2019 (COVID-19) epidemic on negative emotions, such as anxiety, depression, fear, and stress, in Korean college students. The study recruited students from J University and conducted interviews across three time points, namely, March 2019, March 2020, and November 2020. For three time points, the participants responded to structured questions about situations they may have encountered and they were asked to summarize their responses. Repeated-measures ANOVAs were performed to examine whether differences exist in negative emotions between time points. Furthermore, polynomial trend analyses were conducted to examine resultant patterns over time. The results revealed that negative emotions displayed significant differences between time points. Moreover, trend analyses revealed a curvilinear pattern, which indicates that negative emotions increased and were then sustained. These findings suggest that negative emotions may continue to become prevalent among college students with the increased impacts of the ongoing COVID-19 pandemic. The study discussed the need for psychological support systems, such as stress management and psychological counseling, for college students.

• KIPS Transactions on Computer and Communication Systems
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• v.11 no.5
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• pp.157-166
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• 2022

Exercise is necessary for a healthy life, but it is recommended that it be conducted in a non-face-to-face environment in the context of an epidemic such as COVID-19. However, in the existing non-face-to-face exercise content, it is possible to recognize exercise movements, but the process of interpreting and providing feedback information is not automated. Therefore, in this paper, to solve this problem, we propose a method of creating a formalized rule to track the contents of exercise and the motions that constitute it. To make such a rule, first make a rule for the overall exercise content, and then create a tracking rule for the motions that make up the exercise. A motion tracking rule can be created by dividing the motion into steps and defining a key frame pose that divides the steps, and creating a transition rule between states and states represented by the key frame poses. The rules created in this way are premised on the use of posture and motion recognition technology using motion capture equipment, and are used for logical development for automation of application of these technologies. By using the rules proposed in this paper, not only recognizing the motions appearing in the exercise process, but also automating the interpretation of the entire motion process, making it possible to produce more advanced contents such as an artificial intelligence training system. Accordingly, the quality of feedback on the exercise process can be improved.

• Economic and Environmental Geology
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• v.55 no.4
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• pp.421-428
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• 2022

This study analyzes emerging earthquake and space use technologies from the latest Korean and Japanese scientific and technological foresights in 2022 and 2019, respectively. Unlike the earthquake prediction and early warning technologies presented in the 2017 study, the emerging earthquake technologies in 2022 in Korea was described as an earthquake/complex disaster information technology and public data platform. Many detailed future technologies were presented in Japan's 2019 survey, which includes largescale earthquake prediction, induced earthquake, national liquefaction risk, wide-scale stress measurement; and monitoring by Internet of Things (IoT) or artificial intelligence (AI) observation & analysis. The latest emerging space use technology in Korea and Japan were presented in more detail as robotic mining technology for water/ice, Helium-3, and rare earth metals, and manned station technology that utilizes local resources on the moon and Mars. The technological realization year forecasting in 2019 was delayed by 4-10 years from the prediction in 2015, which could be greater due to the Corona 19 epidemic, the declaration of carbon neutrality in Korea and Japan in 2020 and the Russo-Ukrainian War in 2022. However, it is required to more active research on earthquake and space technologies linked to information technology.

• Korean Journal of Veterinary Service
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• v.45 no.2
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• pp.71-77
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• 2022

African swine fever (ASF) is a fatal viral disease in pigs, with a short incubation period and causing immediate death. Few studies exist on the Asian epidemic ASF virus (ASFV) challenge in older pigs, including growing and fattening pigs and sows. We aimed to investigate clinical outcomes, pathomorphological lesions, and viral distribution in organs of 3-month-old growing pigs that were inoculated with the ASFV isolated in Vietnam. The clinical outcomes were recorded daily, and the dead or euthanized pigs immediately underwent necropsy. Viral loads were determined in 10 major organs using quantitative polymerase chain reaction. The average incubation period in growing pigs was more delayed (5.2±0.9 dpi) than that in weaned pigs, and the clinical signs were milder in growing pigs than in weaned pigs. The digestive and respiratory clinical signs in growing pigs showed at the end period of life, but these were observed at an early stage of infection in weaned pigs. The pathomorphological features were severe and nonspecific with hemorrhagic lesions in various organs. The viral loads in organs from growing pigs were higher than those from piglets, and the number of viral copies was related to gross lesions in the tonsil and intestine. In the absence of vaccines against ASF, early clinical detection is important for preventing the spread of the virus. Our findings elucidated that the clinical signs and gross lesions in growing pigs differed from those in weaned pigs, which provide valuable information for diagnosis of pigs with suspected ASF infection.

• The Journal of the Convergence on Culture Technology
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• v.8 no.5
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• pp.369-375
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• 2022

Due to the so-called COVID-19 pandemic, railway service management has also faced an unprecedented situation over the past. This study conducted a survey of customers using high-speed railways during the COVID-19 pandemic to explore the impact of infectious diseases on the railway service customer experience. As a result, customer satisfaction and loyalty increase as customers are more aware of the quarantine-related services provided by railway operators. The moderating role of customer's COVID-19 risk perception was examined as well because there are individual differences in the level of thinking dangerously about Covid-19. As a result, the perceived level of the service's quarantine-related services has a significant impact on customer satisfaction when the customer's risk perception of Covid-19 is at an appropriate level, but its impact is relatively weak when the customer's risk perception is significantly high. Eventually, only the complete extinction of COVID-19 risk will bring a complete recovery to the service industry. Nevertheless, during the epidemic period, it was confirmed that the main service characteristics are that the service operator thoroughly conducts quarantine activities and faithfully communicates with customers.

• Korean Journal of Veterinary Service
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• v.45 no.2
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• pp.117-124
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• 2022

In the event of an outbreak of a livestock epidemic, it has been considered that the existing burial-centered carcass disposal method should be improved ecofriendly for prevention of leachate and odors from burial basically in regard of pathogen inactivation. Therefore, the aim of this study is whether it was possible to treat the carcass of cattle and chickens using the chemical carcass treatment method. It was conducted to establish detailed treatment standards for the chemical treatment method of cattle and chicken carcasses based on the results of the proof of the absence of infectious diseases in cattle chickens. After inoculating cattle carcass with 10 pathogens (foot and mouth disease virus, bovine viral diarrhea virus, Mycobacterium bovis, Mycobacterium avium subsp. Paratuberculosis, Brucella abortus, Bacillus anthracis, Clostridium chauvoei, Clostridium perfringens, Escherichia coli, and Salmonella Typhimurium) and chicken carcasses with low pathogenic avian influenza virus, Clostridium perfringens type C, E. coli and Salmonella Typhimurium, these were treated at 90℃ for 5 hours in a potassium hydroxide liquid solution corresponding to 15% of the body weight. This method liquefies all cadaveric components and inactivates all inoculated pathogens by PCR and culture. Based on these results, it was possible to prove that chemical treatment of cattle and chicken carcasses is effective in killing pathogens and is a safe method without the risk of disease transmission. The chemical treatment method of livestock carcasses can be suggested as an alternative to the current domestic burial-centered livestock carcass treatment method, preventing environmental pollution, and contributing to public health.

• Journal of the Society of Disaster Information
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• v.18 no.4
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• pp.839-846
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• 2022

Purpose: To secure the safety of firefighters who are dispatched to emergency activities for patients with suspected infectious diseases during an epidemic, and to identify the current status of suspected infectious disease patients by region based on the information collected at the site, and manage firefighting infectious diseases that can be controlled and supported I want to develop a system. Method: Develop a smartphone app that can classify suspected infectious disease patients to check whether an infectious disease is suspected, and develop a disposable NFC tag for patient identification to prevent infection from suspected infectious disease patients. Develop a management system that collects and analyzes data related to emergency patients with suspected infectious disease input from the field and provides them to relevant business personnel to evaluate whether the transport of emergency patients with suspected infectious disease is improved. Result: As a result of the experiment, it was possible to determine whether an infectious disease was suspected through the algorithm implemented in the smartphone app, and the retransfer rate was significantly reduced by transferring to an appropriate hospital. Conclusion: Through this study, the possibility of improving emergency medical services by applying ICT technology to emergency medical services was confirmed. It is expected that the safety of paramedics will be actively secured.

• Journal of Life Science
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• v.33 no.2
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• pp.199-207
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• 2023

To prepare for the threat of a future epidemic in the post-COVID-19 era, research based on the one-health concept (i.e., the health of humans, animals, and the environment as "one") is essential. Cross-species infections are being identified as a result of the high infection rate and viral load of SARS-CoV-2 in humans. The possibility of transmission of SARS-CoV-2 from humans to mink has been determined. In addition, the transmission of SARS-CoV-2 from humans to cats through contact has been considered possible. The data so far show that livestock and poultry are less likely to be infected with SARS-CoV-2. However, if infections are established through a new mutation, the resulting diseases are expected to have enormous ripple effects on various fields, such as human food security, the economy, and trade. In addition, there are concerns about the endemic prospect of SARS-CoV-2 and the high accessibility of companion animals. This is because the evolution of the virus likely occurs in animal hosts. Once SARS-CoV-2 is established in other species, they might serve as intermediate hosts for the re-emergence of the virus in the human population. Thus, it is necessary to ensure a rapid response to future outbreaks by accumulating research data on the animal infection of SARS-CoV-2. These data can have implications for the development of animal models for vaccines and therapeutics against SARS-CoV-2. Therefore, in this study, epidemiological reviews were analyzed, and response strategies against SARS-CoV-2 infection in animals were presented using the One-health approach.

• Tuberculosis and Respiratory Diseases
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• v.86 no.2
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• pp.82-93
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• 2023

Tuberculosis (TB) is a significant public health concern. Globally, TB is among the top 10 and the leading cause of death due to a single infectious agent. Providing standard anti-TB therapy for at least 6 months is recommended as one of the crucial strategies to control the TB epidemic. However, the long duration of TB treatment raised the issue of non-adherence. Non-adherence to TB therapy could negatively affect clinical and public health outcomes. Thus, directly observed therapy (DOT) has been introduced as a standard strategy to improve anti-TB medication adherence. Nonetheless, the DOT approach has been criticized due to inconvenience, stigma, reduced economic productivity, and reduced quality of life, which ultimately could complicate adherence issues. Apart from that, its effectiveness in improving anti-TB adherence is debatable. Therefore, digital technology could be an essential tool to enhance the implementation of DOT. Incorporating the health belief model (HBM) into digital technology can further increase its effectiveness in changing behavior and improving medication adherence. This article aimed to review the latest evidence regarding TB medication non-adherence, its associated factors, DOT's efficacy and its alternatives, and the use of digital technology and HBM in improving medication adherence. This paper used the narrative review methodology to analyze related articles to address the study objectives. Conventional DOT has several disadvantages in TB management. Integrating HBM in digital technology development is potentially effective in improving medication adherence. Digital technology provides an opportunity to improve medication adherence to overcome various issues related to DOT implementation.