• Korean Journal of Environmental Biology
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• v.21 no.1
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• pp.72-76
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• 2003

We investigated the effects of molting-hormone insecticide tebufenozide on fourth larvae of the midge C. flaviplumuon in growth development from fourth-instar to adult. Fourth-instar larvae were exposed test concentrations were chosen control, 10 $\mu\textrm{g}$$L^{-1}$, 30 $\mu\textrm{g}$$L^{-1}$, 60 $\mu\textrm{g}$$L^{-1}$ and 100$\mu\textrm{g}$$L^{-1}$. In control and 10 $\mu\textrm{g}$$L^{-1}$, 10~20% individuals succeed adults while low emergence rates were observed surplus 30 $\mu\textrm{g}$$L^{-1}$. Death larvae appeared a various day along the concentration. We observed the converged day: control, 10 $\mu\textrm{g}$$L^{-1}$, 30 $\mu\textrm{g}$$L^{-1}$ and 60~100 $\mu\textrm{g}$$L^{-1}$ were day 4 to day 18, day 13 to day 16, day 9 to day 17 and day 9 to day 15, respectively. Therefore we concerned a tendency that exposure concentration was high, death period was short. Also, due to molting hormone disruption, development of midge was postponed relatively low concentration such as 10 $\mu\textrm{g}$$L^{-1}$. The converged days of pupa stage revealed control, 10 $\mu\textrm{g}$$L^{-1}$, 30 $\mu\textrm{g}$$L^{-1}$ and 60~100$\mu\textrm{g}$$L^{-1}$ were day 11~15, day 16~20, day 9~15 and day 5~9, respectively. About 10% individuals grow up the pupa-stage in 60~100 $\mu\textrm{g}$$L^{-1}$ condition. Sex ratio of the emerged adults was not different in this study. Death pupae frequently appeared in day 13~16 in control, day 6~23 in 10 $\mu\textrm{g}$$L^{-1}$, day 13~16 in 30 $\mu\textrm{g}$$L^{-1}$ and day 6~16 in 60~100 $\mu\textrm{g}$$L^{-1}$.

• Animal cells and systems
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• v.14 no.1
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• pp.17-23
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• 2010

We isolated warm temperature acclimation-related protein 65-kDa (Wap65) cDNA from the liver of olive flounder and investigated the mRNA expression of Wap65 and HSP70 in olive flounder exposed to osmotic (17.5, 8.75, and 4 psu) and thermal stress (25 and $30^{\circ}C$). The mRNA expression of Wap65 and HSP70 was increased by thermal stress. The mRNA expression of HSP70 was also increased by osmotic stress, whereas no significant change in Wap65 expression was detected. These results indicate that Wap65 mRNA expression occurs specifically in response to increases in water temperature, but not in response to osmotic stress. Plasma cortisol levels were also increased by osmotic and thermal stress. We also utilized the stress hormone cortisol to examine whether Wap65 expression is thermal-stress-specific. Cortisol treatment increased HSP70 mRNA expression in vitro, but had no significant effect on Wap65 mRNA expression. Thus, thermal stress, but not osmotic stress, induces Wap65 expression.

• Journal of Haehwa Medicine
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• v.18 no.2
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• pp.105-111
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• 2009

Melasma is a common disorder that causes dark colored patches. It generally causes brown spots on the face, especially on the forehead, cheeks, and upper lips. The pattern of patches has bilateral symmetry in yellowish-brown to gray-brown colors. It is much more common in women than in men. Melasma is considered to be caused by environmental and physical constitutional factors and often occurs when a woman's hormone changes by pregnancy or the use of oral contraceptive pills. It is important to combine oriental medicine and Sasang constitutional medicine for treatment of Melasma. Normal treatment of Melasma includes warming oneself, removal of the emotional stress factors, and good nutrition.

• Proceedings of the Korean Society of Toxicology Conference
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• 2001.05a
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• pp.167-167
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• 2001

Peroxisome proliferator-activated receptors(PPARs) are member of the neuclear hormone receptor superfamiliy of ligand-dependent transcription factors that heterodimerizes with the retinoid X receptor to function as a transcriptional regulator. They are divided into three subtypes(PPAR-$\alpha$, $\beta$ and ${\gamma}$).(omitted)

• Toxicological Research
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• v.31 no.4
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• pp.415-420
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• 2015

The purpose of the present study is to investigate the correlations between food intake behavior and job stress level and neuropeptide hormone concentrations. Job strain and food intake behavior were first identified using a self-reported questionnaire, concentrations of neuropeptide hormones (adiponectin, brain derived neurotrophic factor [BDNF], leptin, and ghrelin) were determined, and the correlations were analyzed. In the results, job strain showed significant correlations with adiponectin (odds ratio [OR], 1.220; 95% confidence interval [CI], 1.001~1.498; p < 0.05) and BDNF (OR, 0.793; 95% CI, 0.646~0.974; p < 0.05), and ghrelin exhibited a significant correlation with food intake score (OR, 0.911; 95% CI, 0.842~0.985, p < 0.05). These results suggest that job stress affects food intake regulation by altering the physiological concentrations of neuropeptide hormones as well as emotional status.

• Bulletin of the Korean Chemical Society
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• v.32 no.8
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• pp.2560-2564
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• 2011

Mesoporous silicon dioxide (meso-$SiO_2$) was prepared using cetyltrimethylammonium bromide as the structure-directing reagent and tetraethyl orthosicate as the silicon source. The influence of pH value on the adsorption behavior of bisphenol A (BPA) was investigated. The adsorption capacity of BPA onto meso-$SiO_2$ increases slightly with pH value from 2 to 6, and then gradually decreases as further improving pH value. The effect of temperature was also studied, and the adsorption capacity of BPA gradually declines with increasing temperature. The adsorption kinetics and thermodynamics of BPA were examined. It is found that the adsorption of BPA onto meso-$SiO_2$ is in good agreement with Langmuir adsorption model. The rate constant of adsorption is $5.17{\times}10^{-3}g\;mg^{-1}\;min^{-1}$, and the maximum adsorption capacity is as high as 353.4 $mg\;g^{-1}$ at 20 $^{\circ}C$.

• Korean journal of applied entomology
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• v.31 no.3
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• pp.289-303
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• 1992

Investigation of the environmental impact of widespread pesticide use has revealed a virtue/vice relationship. Although many pesticides perform their function and disappear without harm to the environment, others persist beyond their useful purpose and cause direct of indirect hazard to man, domestic animals and wildlife. Concurrently, many pests have rapidly adjusted to chemical control practices through changes in behavior that avoid exposure to pesticides of throuth genetic selection for populations resistant to the toxicants. The prospect of losing control over insect herbivores and desease vectors and returning to the days of global hunger and disease is unthinkable. Fortunately, from basic studies of insect and plant biology many opportunities for the development of safe, selective and environmentally pacific strategies for insect pest management are being realized.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.05a
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• pp.95.2-95
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• 2003

Ketoconazole is a well-studied drug that blocks fungal growth and testosterone synthesis in humans and rodents by inhibiting the activity of cytochrome P-450 enzymes. But there were no reports that ketoconazole affects on enzymes related to degradation of testosterone. Aromatase converts testosterone to estradiol. Change of aromatase protein level may destroy hormone homeostasis. (omitted)

• Biomedical Science Letters
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• v.11 no.3
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• pp.333-336
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• 2005

Environmental endocrine disruptors are very toxic to the animals including humans. They are hormone-like acting chemicals which can be found in our normal daily life. We have examined the toxic effect of bisphenol A and if lactic acid bacteria could suppress this toxic effect. Thirty rats were divided into three groups (control, bisphenol A treated, bisphenol A and lactic acid bacteria treated). Treatments were carried out at an interval of 12 hours for each group. Control group showed normal and clear morphology of tissues. Cells were fine in their shape and color, and density was high enough for the normal function. However, bisphenol A treated group was abnormally destructed in cell morphology. In the testis, sperms were totally destructed. When treated with lactic acid bacteria together, the toxic effect of bisphenol A was clearly decreased. This study indicated that bisphenol A was toxic in any concentration especially for the liver and testis, however, lactic acid bacteria could suppress the toxic effects of bisphenol A.

• Proceedings of the Korean Society of Toxicology Conference
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• 2005.05a
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• pp.147-148
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• 2005