• 한국환경보건학회지
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• 제38권5호
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• pp.431-437
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• 2012

Objectives: This study aims to investigate the effects of voice disorders on changes in stress among people with damaged larynxes. To accomplish this, physiological changes and reductions in the stress of Sprague-Dawley rats whose larynx had been damaged were investigated after the laboratory animals were administered kudzu leaf extracts with sedative effects. Methods: In the experiment, a total of 24 rats were divided into four groups of six rats, including the normal group, control group, experimental group 1, and experimental group 2. After orally administering to the subjects a predetermined amount of the extract at a specific time (once per day over five weeks), changes in physiological functions, internal organ weight, cortisol, estrogen, and progesterone in the subjects were examined, and an immunological test was conducted on their brain tissues. Results: Statistical significance was seen in the experimental group as opposed to the control group and the results were similar to those of the normal group. Conclusions: In consideration of these results, it is deemed that there are severe effects on stress due to voice disorders and that the administration of kudzu leaf extracts results in improvement in stress.

• Journal of Nutrition and Health
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• 제32권6호
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• pp.713-725
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• 1999

Women have a greater incidence of coronary heart disease(CHD) after menopause. It relates to hormone imbalance-induced changes in known CHD risk factors, especially hyperlipidemia. Accordingly, once women are diagnosed, the rate of morbidity and mortality is greater than for men. Thus, preventive strategies are critical to improve the quality oflife in the later years for women. The purpose of ths study was to explore the difference of anthropometric, environmental factors and food behaviors between normocholesterolemia and hypercholesterolemia within postmenopausal women. The subjects were classified as normocholesterolemia and hypercholesterolemia based on the Guideline for Korean Hyperlipidemia. The results obtained are summarized as follows. The distributions of general characteristics such as age, family income, occupation status, age at menarche, and menopausal period were not significantly different between the normocholesterolemia group and hypercholesterolemia group. The anthropometric factors such as body mass index(BMI) and waist hip ratio(WHR) were not significantly different between the normocholesteroemia group and the hypercholesterolemia group but odds ratio of hypercholesterolemia group was higher than that of normocholesterolemia but not significant. Aerobic activity more than 1hours/day was significantly related to low serum cholesterol concentration. Eating behaviors related to regular meal time, regular breakfast habit, and slow meal speed were related to low serum cholesterol concentration. Eating the chicken without skin was significantly related to low serum cholesterol concentration. Our data indicate that desirable eating habit, aerobic activity more than 1hr/day are important factors of serum cholesterol concentrations in postmenopausal women. The result of this study provide information that is important in designing appropriate dietary guidelines for hypercholesterolemia in postmenopausal women.

• 환경위생공학
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• 제6권2호
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• pp.59-68
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• 1991

The word of stress was wsed in the field of physics as a external force from 17th century, but the meaning of this stress had chafed to the internal and exteral demand fort the human body in medical area. All the stumulants which make stress was called as j stressor. When animals get stress blucose excreted from liver to adapt for the emergent state ant some related hormone secrete convert protein and lipid to glucose for the purpose of energy supply to muscle. As a results heart rate, blood pressure, respiration rate are increased and musclse are strengthed. These physiolgical reactions ate controlled by autonomic nerve system under the control of hyothalamus in brain. Autonomic nerve system and endocrinary system are react harmoiously to stress reaction. According to the stress reaction, adrenomedullary system are stimulated, and epinephrine, morepinephrine are exceted. Author experimented the effect of the immobilizational stress to rat by analyzing the variaition of catecholamine secrction, the Na concentration and the effect of the antistresf effect by Panax Ginseng which is a traditional Korean herb medicine. The concentration of the norepinephrine, epinephrin, and dopamin in normal rat are 1 578 ng/ml, 0.365 ng/ml, and 0.731 ng/ml respectively, but in the immobilyzed stress groIn the concentration were increased to 1.915 ng.ml, 0.854 ng/ml, and 2,361 ng/ml which she the high show the higher concentration of catecholamine to stressor.

• 한국환경농학회지
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• 제27권4호
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• pp.447-455
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• 2008

Recombinant yeast estrogenicity (YES) assay was used as a bioanalytical tool in order to screen $17{\beta}$-estradiol in the soil samples collected from different sites of South Korea. Solvent extraction and supercritical fluid extraction (SFE) methods were compared for the extraction of the estradiol from the soils. Most high detection of the estradiol based on YES assay was observed in the soils extracted with methanol. Different types of estrogenic hormones including $17{\beta}$-estradiol were suggested to be possibly exiting in the soils, since the methanol extracts of the soils showed an estrogenic activity that was not observed in the hexane extracts of the soil. SFE extracts showed estrogenic activity in some of the samples but methanol extract showed best activity.

• 한국환경보건학회지
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• 제39권1호
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• pp.43-47
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• 2013

Objectives: We investigated the effects of Korean gastrodia and bee pollen on testosterone production in Sprague-Dawley rats. Methods: This study measured the body weight, consumption of food and water, and serum testosterone concentration in SD rats fed for four weeks with gastrodia and bee pollen. Results: The average body weights after four weeks were $375{\pm}2g$ for the control group, $358{\pm}3g$ for gastrodia consumption, and $354{\pm}2g$ and $367{\pm}8g$ for acorn pollen and Siberian gooseberry pollen, respectively. The average food consumption in SD rats over the four weeks in the control was 23.6 g for gastrodia consumption, 24.3 g and 24.9 g for acorn pollen and Siberian gooseberry pollen, respectively. The average water consumption over the four weeks was 38.33 ml in the control group, 35.0 ml for gastrodia treatment, and 33.3 ml and 33.3 ml for acorn pollen and Siberian gooseberry pollen treatment, respectively. The testosterone secretion levels in the serum of male rats were increased by gastrodia, acorn pollen, and Siberian gooseberry pollen (2.68, 3.00, and 3.28 pg/ml, respectively) compared to the control group (2.23 pg/ml). Conclusions: These results suggest that gastrodia or bee pollen may be developed as a complementary medicine to improve sexual hormone production.

• 한국환경생물학회:학술대회논문집
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• 한국환경생물학회 2003년도 학술대회
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• pp.7-11
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• 2003

Interactions of both feminizing and masculinizing chemicals inducing imposex in gastropod were investigated with a long-term exposure experiment. Imposex-free rock shell(Thais-clavigera)was exposed to TBT and other antagonistic chemicals (nonylphenol and DDT), P450 inducer (phenobarbital) and natural sex hormone (estrogen) mixtures for 60 days. None of imposexed-females were found in control, sham (ethanol) and testosterone exposure group, on the other hand imposex was induced in the TBT and all the TBT+antagonist mixture groups. After 60-day exposure, frequency of imposexed-female ranged from 31-68%. Female mean penis length (FMPL) of imposexed-female ranged from 0.87-2.58 mm, and relative penis length indices were from 7.2 to 21.2%. However, the degrees of imposex were different among the exposure groups. The FMPLS of three exposure groups (TBT+estrogen, + DDT and +nonylphe- not) were less than that of the TBT exposure group. Ethoxyresorufin-O-deethylase (EROD) activities in gastropod decreased in the TBT and all the TBT+antagonist ekposure groups compared to the control group. A negative correlation was abtained between TBT body residue and EROD activity, while a positive relationship was obtained between 737 body residue and the degree of imposex except for the TBT +DDT exposure group. Although 737 concentration was relatively high in the TBT+DDT exposure group, the TBT +DDT exposure group demonstrated low EROD activity and low degree of imposex. These results indicate that a certain antagonistic effect of DDT occurred in induction of imposex by TBT.

• 한국환경생물학회:학술대회논문집
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• 한국환경생물학회 2003년도 학술대회
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• pp.12-15
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• 2003

The effects of the non-steroidal ecdysteroid agonist tebufenozide on larvae of C. faviplumus and C. riparius were tested in the laboratory. In the most treatments it reached a statistically significant difference from the control condition. As the concentration of tebufenozide was increased, a relatively larger proportion of the observed mortality was associated with the metamorphosis and molting process. Also, the larval mortality of the first larvae was higher than the fourth-instar larvae in C. riparius. In terms of development, the effects of tebufenozide were delayed growth stage in relatively lower concentration such as 10 $\mu\textrm{g}$/L treatments. Based on the mortality, the susceptibility followed the first-instar C. riparius > the fourth-instar C. flaviplumus > the fourth-instal C. riparius. The morphological effects showed that the first and second segments of body of exposed larvae with tebufenozide expanded slowly and not made a complete cephalothorax of pupae during long times or days. And the head capsule slipped down and forward, revealing a fragile and non-pigmented, unsclerotized new head capsule. There was obvious significant difference in the male/female ratio in contaminated fourth larvae of C. riparius. Also, due to the different emergence periods of male/female in low insecticide concentrations, mating chances or opportunities of insects should be decreased. Accordingly, ecological strategies for keeping of sustainable populations should be disrupted.

• Fisheries and Aquatic Sciences
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• 제26권4호
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• pp.241-255
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• 2023

The robust development of frog farming offered high economic benefits but created a large waste residue of frog bones and skin that received little attention. Over the years, inedible by-products have often been processed into biomolecules of potential value and environmental benefits, such as collagen, gelatin, and bioactive peptides. An overview of bioactive compounds on frog skins from various countries indicated that brevinin was the most abundant biological peptide found in frog skin. Other remaining compounds also possessed their highlighted activities, including antibacterial, stimulating insulin release and gastric hormone release, anti-cancer, and neuroregulatory. Notably, various components have been analyzed in the structure and sequence to give meaningful insight into clustering components related to their biological activity. This review may create a source of raw materials for the developmental research of by-products from frog skin and concomitantly reduce environmental pollution.

• 대한화학회지
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• 제58권6호
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• pp.590-599
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• 2014

환경문제를 해결하는데 중요한 환경교육은 학교 현장에서 효과적으로 이루어지려면 교사들의 인식이 많은 영향을 미칠 것이다. 따라서 본 연구는 부산시 중학교 교사들의 환경 문제에 대한 인식을 2007년 및 2012년 두 차례에 걸쳐 설문조사를 하였다. 2007년 교사 200명, 2012년 300명의 교사들을 대상으로 설문조사를 실시하였으며 471명의 자료가 분석되었다. 교사들의 환경 문제에 대한 인식 수준을 시점, 경력, 전공 교과를 기준으로 비교 분석하여 일선 교육 현장에서의 환경교육을 위한 기초자료를 제시하고자 한다. 그 결과는 다음과 같다. 첫째, 두 시점 간 교사들의 환경 문제 인식 차이는 통계적으로 유의미하였다(p<.01). 특히, 현대 환경 문제 인식, 이산화탄소 배출권 제도 등은 과학 전공 교사 및 비과학 전공 교사들에게 인식 차이가 뚜렷하게 나타났다. 이는 최근 들어 세계 곳곳에서 나타나는 기상이변과 무분별한 소비위주의 생활방식의 심각성에 기인한다고 여겨진다. 둘째, 경력에 따른 환경 문제의 인식 차이가 통계적으로 유의미하였다(p<.01). 전체적으로 현대 환경 문제 인식, 이산화탄소 배출권 제도, 오존층 파괴, 적조현상, 환경 정책 등에서 인식 차이가 뚜렷하게 나타났다. 전공과 무관하게 경력이 많은 교사가 환경오염의 심각성, 환경보전의 필요성, 건강의 중요성 등을 인식하는 정도가 높았다. 셋째, 과학 전공 교사 및 비과학 전공 교사에 따라 환경 문제 인식 차이는 통계적으로 유의미하였다(p<.01). 특히 현대 환경 문제 인식, 이산화탄소 배출권 제도, 오존층 파괴, 핵폐기물, 환경 호르몬, 적조 현상 등 환경 문제 전반에 걸쳐 과학 전공 교사 및 비과학 전공 교사들의 인식 차이가 뚜렷하였다.

• 환경생물
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• 제21권3호
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• pp.286-291
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• 2003

탈피호르몬의 작용을 방해하는 농약제인 tebufenozide 를 알에서 부화한 지 7일째의 C. riparius에 처리하여 성충이 될 때까지의 생장과정을 연구하였다. C. riparius 에 control, 10 ${\mu}g\; L^{-1},\; 30 \; {\mu}g\; L^{-1},\; 60 {\mu}g\; L^{-1}$와 100 ${\mu}g \;L^{-1}$의 농도로 약제를 처리하였다. 전체적으로 약제를 처리한 하루 후인 D12에 16%가 치사되었으며 치사 집중 시기는 D12에서 D16까지로 44%가 살충되는 것으로 나타났다. 유충의 치사 발생은 10 ${\mu}g \;L^{-1}$에서는 D12에서 급격히 증가되기 시작하여 시간의 경과에 따라 지속적으로 증가되었다. 30 ${\mu}g \;L^{-1}$이상에서는 D12-D16에 치사가 집중되어 노출농도가 높을수록 치사되는데 걸리는 기간이 짧아지는 경향을 보였다. 비처리시에는 실험에 투입된 개체수의 78%가 번데기에 도달하였으나 10${\mu}g \;L^{-1}$에서는 17%에 그쳤으며 30${\mu}g \;L^{-1}$에서는 5%에 불과하였다. 비처리에서는 75%가 성충으로 우화에 성공하였으나 10${\mu}g \;L^{-1}$ 이상에서는 소수 관찰되었다. 성충으로 성공한 개체는 D26에서 D29까지 집중적으로 우화가 발생하였다. 번데기 상태에서 치사가 나타난 시기는 30 ${\mu}g \;L^{-1}$에서는 D19-D20에 나타난 반면에 비처리시에는 D32, 10${\mu}g \;L^{-1}$에서는 D33에서부터 나타나기 시작하였다. 비처리시에 D32-D34에 번데기 치사가 발생하였으나 10 ${\mu}g \;L^{-1}$ 노출에서는 오히려 더 늦어져 D33-D37까지 번데기 치사가 관찰되었다. 저농도인 10${\mu}g \;L^{-1}$에서는 탈피호르몬 작용을 교란시키는 tebufenozide의 효과로 생각단계가 지연되고 있음을 볼 수 있었다.