• Proceedings of the PSK Conference
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• 2003.10a
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• pp.47-49
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• 2003

Development of drug delivery systems has been recognized as one of portfolios to gain a competitive edge in pharmaceutical industry over 30 years. The application of drug delivery technologies offers pharmaceutical companies and patients several therapeutic benefits, including improving efficacy and adverse effect profiles, enhancing patient compliance and potentially regenerating unsuccessful drugs. (omitted)

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.6
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• pp.105-113
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• 2010

In this study, a feasibility test of liquid petroleum gas (LPG) compression ignition (CI) engine has been carried out to study the effectiveness of cetane enhancing additive: Di-tertiary-butyl peroxide (DTBP). Performance and emissions characteristics of a CI engine fuelled with DTBP blended LPG fuel were examined. Also, the effect of EGR (exhaust gas recirculation) on the combustion and emissions characteristics has been investigated. Results showed that stable engine operation over a wide range of the engine loads was possible. Exhaust emissions measurements showed that hydrocarbon were decreased with the blended fuel at enhancing cetane number. Furthermore, the combustion stability of LPG with a cetane number improver was equivalent to that of commercial Diesel fuel. Increasing the EGR rate leads to deteriorate the IMEP (indicated mean effective pressure) and increase the ignition delay. It was found that the exhaust emissions with the EGR resulted in a very large reduction in nitrogen oxides at the expense of higher THC and CO emissions. Considering the results of engine performance and exhaust emissions, LPG blended fuel of enhancing cetane number could be used as an alternative fuel for diesel in a CI engine.

• Proceedings of the Korea Institute of Applied Superconductivity and Cryogenics Conference
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• 2000.02a
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• pp.101-103
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• 2000

In the present work, we have investigated the combined effect of high-energy milling and Agb addition on microstructure and superconducting properties for Bi-2223/Ag. tape. The addition of siver plays an important role in enhancing liquid phase formation, Resulting in densification and cracking during solidification. Further study is needed for the optimization of Ag content and heat-treatment which can reduce the cracking.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2001.11b
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• pp.882-887
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• 2001

This paper deals with the effect of mass-spring-mass resonance that is a characteristics of the multi-layered panels in order to enhance sound insulation performance. From theoretical and experimental investigation, it is evident that tuning mass-spring-mass resonance by controlling elastic modulus of the core materials is very important to improve the STC value without increasing the weight of panels, resulting in enhancing STC value more than 10 dB.

• Journal of Science Education
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• v.36 no.2
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• pp.251-262
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• 2012

In this study, we develop 15 learning programs to enhance the variable identification and control abilities for the middle school students and analyze the effect of the programs applied to the class. To increase the learning effect of the variable identification and control abilities, we design the programs so that the students can monitor their thinking processes and also they can evaluate the results from their cognitive activities objectively. We analyze the effect of the programs applied to the class and the results show that the test group, which uses the program, marks higher scores in the variable identification abilities compared to the control group. Also, the test group has the increased level of logic to control the variables. Especially, the effect is higher with the students who do not have any logic to control the variables. From the results, we know that it is possible to improve the variable identification and control abilities of the students through the meta-cognitive learning programs developed by us. Furthermore, the results show that the score of variable control abilities positively correlate with that of meta-cognitive level. It means that the meta-cognitive strategy meaningfully increases the variable control abilities of middle school students.

• Korean Journal of Pharmacognosy
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• v.45 no.1
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• pp.48-54
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• 2014

Alzheimer's disease is progressive neurodegenerative disorder by the loss of memory and learning abilities. Codonopsis lanceolata (C. lanceolata) is traditional medicinal plant used for the treatment of inflammatory diseases. The aim of study was to evaluate the effect of steamed C. lanceolata on scopolamine-induced memory impairment in the Morris water maze test and passive avoidance test. In addition, this study investigated the neuroprotective effects of steamed C. lanceolata on glutamate-induced cell death in HT22 cells using MTT assay. The results showed that steamed C. lanceolata (500 mg/kg body weight, p.o.) reversed spatial memory impairment by scopolamine in Morris water maze test and passive avoidance test. Steamed C. lanceolata attenuated memory impairment by scopolamine compared with common C. lanceolata. In addition, administration of steamed C. lanceolata significantly also reduced cell death. We suggest that steaming process more improve cognitive enhancing and neuroprotective effect of C. lanceolata than common C. lanceolata.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.554-565
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• 2020

This study found out a process of effects of professional identity recognized by social workers on their job satisfaction and organizational commitment, and verified a mediated effect caused by working environment through the process. A survey for data collection was conducted among 205 employees of social welfare facilities located in Gyeonggi Province. Collected data was analyzed by using structural equation modeling. The data analysis showed that first, professional identity has an extremely meaningful positive effect on job satisfaction. Second, professional identity has a meaningful positive effect on organizational commitment. Third, working environment has a partial mediated effect on relationships between professional identity and job satisfaction, between professional identity and organizational commitment. These results proved that the enhancement of job satisfaction and organizational commitment of social workers is based on enhancing professional identity, and organizational commitment can be enhanced by the working environment. Based on the results, this study discussed practical plans for enhancing job satisfaction and organizational commitment of social workers.

• KSBB Journal
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• v.14 no.4
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• pp.396-402
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• 1999

To verify enchancing effect of polycation of polycation on the retroviral infecivity, we directly measured the binding affinity of retroviruses to the target cells in the presence or in the absence of polybrene with R18 fluorescence assay and examined the effect of the polymers on the relationship between the host cell and the retroviral infecity. There was no difference in the effect of the types of charge of the polymer on the binding affinity. However, polycations, in general, show effect on the retrovirus infecity. This results suggest that the enhancing effect of polybrene and other polycations on the infecity is not due to the binding step but due to the post-binding steps, especially the internalization step. With the result of the internalization of FITC-labeled poly-L-lysine into the host cells, it is suggested that the uptake of polycations into the host cells would play a crucial role in the intermalization of retroviruses.

• Journal of Life Science
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• v.19 no.5
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• pp.688-691
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• 2009

The methanol extract of muskmelon (Cucumis melo) has been investigated for its cognition enhancing effects by evaluation of inhibitory activities on acetylcholinesterase, a degrading enzyme of acetylcholine, a brain neurotransmitter, and ${\beta}$- secretase, which forms the ${\beta}$-amyloid toxic protein from its precursor protein. A passive avoidance task, one of the animal model experiments for learning and memory, was also performed. As a result, the melon extract showed 15.8% and 35.3% inhibition on acetylcholinesterase and ${\beta}$-secretase, respectively, with a final concentration of 100 mg/ml. In the animal model test, melon extract significantly (p<0.05) lengthened the step-through latency time by 22.7% compared to the control group, suggesting that melon extract has, indeed, an effect on cognition enhancement.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.286-286
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• 1996

In order to elucidate the mechanism of action of transdermal absorption-enhancing compounds, i.e., pyrrolidone derivatives (2-pyrrolidone, 1-methyl-2-pyrrolidone, 1-ethyl-2-pyrrolidone, 1,5-dimethyl-pyrrolidone and 5-methyl-2-pyrrolidone), multilamellar liposome was prepared from the simulated stratum corneum lipid and employed as a model system for the barrier function of the stratum corneum. The liposomal membrane of the stratum corneum lipid liposome (SCLL) behaves as an osmometer and has an excellent barrier function. In addition, its phase transition temperatures are similar to those of human stratum corneum intercellular lipid region. Therefore, SCLL seems to be a useful skin model. To estimate the barrier function of SCLL, the osmotic behavior of SCLL was measured in the presence of pyrrolidone derivatives and the effect on the phase transition temperature of SCLL was also investigated using differential calorimetry. Above a certain concentration (MLAC), enhances perturb the barrier function of the liposome. The relationship between MLACs and the partition coefficient of the pyrrolidone derivatives was observed; the greater the partition coefficients, the smaller the MLAC. This suggests that the more hydrophobic enhancers penetrate into the lipid layer more easily and reduce the barrier function of membrane more effectively. The results of differential scanning thermograms of the SCLL suggest that the pyrrolidone derivatives had incorporated into the lipid layer in the liposome and increased the fluidity of the lipid layer in the liposome. Such activity might have some correlation with the transdermal absorption-enhancing activity these compounds.