• Title/Summary/Keyword: enhancing effect

Search Result 2,380, Processing Time 0.028 seconds

EFFECT OF TRYPSIN-DIGESTED BOVINE GROWTH HORMONE ON WHOLE-BODY PROTEIN SYNTHESIS IN VITRO IN CHICKEN EMBRYOS

  • Kita, K.;Hatano, S.;Okumura, J.;Muramatsu, T.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.6 no.2
    • /
    • pp.319-323
    • /
    • 1993
  • The effect of bovine growth hormone digested with trypsin on whole-body protein synthesis in vitro of chicken embryos was investigated by using a whole-embryo culture system. Bovine growth hormone at 5.3 and 530 ng/ml was digested partially and completely with trypsin for 4 min and 18 h, respectively. After culturing chicken embryos with a synthetic medium containing $L-[4-^3H]$ pheylalanine, whole-embryo protein synthesis was determined from the ratio of specific radioactivities of free and protein-bound pheylalanine. Whole-embryo protein synthesis of the control group cultured with no bovine growth hormone was $49.5{\pm}2.2%/d$. There was no significant interaction between digestion time and the concentration of trypsin-digested bovine growth hormone. Tryptic digestion of bovine growth hormone increased fractional synthesis rates of whole-body protein compared to the 0-min groups, and there was no significant difference between the 4-min and 18-h groups. The higher concentration (530 ng/ml) of trypsin-digested bovine growth hormone was more effective in enhancing whole-embryo protein synthesis than the lower concentration (5.3 ng/ml).

PAMAM Dendrimers Augment Inhibitory Effects of Curcumin on Cancer Cell Proliferation: Possible Inhibition of Telomerase

  • Mollazade, Mahdie;Nejati-Koshki, Kazem;Akbarzadeh, Abolfazl;Zarghami, Nosratollah;Nasiri, Marzieh;Jahanban-Esfahlan, Rana;Alibakhshi, Abbas
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.11
    • /
    • pp.6925-6928
    • /
    • 2013
  • Background: Despite numerous useful anticancer properties of curcumin, its utility is limited due to its hydrophobic structure. In this study, we investigated the comparative antiproliferative effect of PAMAM encapsulating curcumin with naked curcumin on the T47D breast cancer cell line. Materials and Methods: Cytotoxic effects of PAMAM dendrimers encapsulating curcumin and curcumin alone were investigated by MTT assay. After treating cells with different concentrations of both curcumin alone and curcumin encapsulated for 24h, telomerase activity was determined by TRAP assay. Results: While PAMAM dendrimers encapsulating curcumin had no cytotoxicity on cancer cells, they decreased the $IC_{50}$ for proliferation and also increased the inhibitory effect on telomerase activity. Conclusions: Considering the non-toxicity in addition to effectiveness for enhancing curcumin anticancer properties, dendrimers could be considered good therapeutic vehicles for this hydrophobic agent.

The Effect of PBL Model on Ethics Awareness in Internet Ethics Learning (인터넷 윤리 수업에서 PBL 모델이 윤리의식에 미치는 영향)

  • Kang, Oh-Han
    • The Journal of Korean Association of Computer Education
    • /
    • v.17 no.1
    • /
    • pp.75-82
    • /
    • 2014
  • This thesis focuses on developing an appropriate model for teaching internet ethics based on problem-based learning, and studying its effect on morality. The PBL model is focused on encouraging participation from students through discussion and essay-writing. To test the validity of the new model, the control group was constructed and was assigned an existing lecture-based model. The research applied the new method at class and compared changes in Internet ethics between two groups. The results showed that the PBL model was more effective in enhancing internet ethics among students than the lecture-based model, and they were statistically valid. Especially, the "responsibility" part within the internet ethics showed the biggest improvement.

  • PDF

The Sequential Mediation Effects of Efficacy Belief about Play and Professional Recognition between Kindergarten Teacher's Emotional Intelligence and Teacher-child Interaction (유치원교사의 정서지능과 교사: 유아 상호작용 간의 관계에서 놀이교수효능감과 교직전문성 인식의 순차적 매개효과)

  • Chung, Mi Ra;Kim, Sei Kyung;Kim, Min Jeong
    • Korean Journal of Childcare and Education
    • /
    • v.12 no.3
    • /
    • pp.137-157
    • /
    • 2016
  • This study examines the effects of teacher's emotional intelligence on teacher-child interaction through the sequential mediation effects of efficacy belief about play and professional recognition. Participants were 268 teachers working at kindergartens in Gyeonggi area. Data were analyzed by descriptive statistic, Pearson's product-moment correlation, and the structural equation model using the SPSS 21.0 and Mplus 6.12 program. The main findings of this study are as follows: First, in regards to the relationship between emotional intelligence and teacher-child interaction, a single mediation effect of efficacy belief about play is significant. But there is no significant mediation effect of the professional recognition. Second, in regards to the pathway from emotional intelligence to teacher-child interaction, the professional recognition precedent mediation model is statistically significant, but efficacy belief about the play precedent mediation model is not significant. Based on the results, a concluding discussion was made regarding methods toward enhancing interaction between teacher and child.

Research on Effects and Possibility of Commercialization of Coptidis Rhizoma Mask Pack (한방 황련 마스크팩의 효능 검증 및 상품화 가능성 조사)

  • Lee, Kyou-Young;Hong, Chul-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
    • /
    • v.28 no.1
    • /
    • pp.100-108
    • /
    • 2015
  • Objectives : This study was planned to examine the enhancing effect of Coptidis Rhizoma mask pack on water, oil contents and skin texture, and to check the possibility of commercialization. Methods : We measured the change of water, oil contents and skin texture before and after the use of Coptidis Rhizoma mask pack. Measuring was conducted twice at an interval of ten days using accurate SK-03 skin analyzer. Measuring site was right and left SI18 and CV24 acupoints. Results : We can examine the improvement of water, oil contents and skin texture on every acupoints measured, except for CV24. On CV24, no difference was observed from water contents of both 1st, 2nd visit, and skin texture of 1st visit. Conclusions : We could confirm the boosting effect of Coptidis Rhizoma mask pack on water, oil contents and skin texture, especially around the SI18 acupoints. We should take follow-up measures to improve the absorption of a liquid herbal medicine around the CV24 acupoint, and heighten the potential for commercialization.

Ultrasonic Inspection of Cracks in Stud Bolts of Reactor Vessels in Nuclear Power Plants by Signal Processing of Differential Operation

  • Choi, Sang-Woo;Lee, Joon-Hyun;Oh, Won-Deok
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.25 no.6
    • /
    • pp.439-445
    • /
    • 2005
  • The stud bolt is one of crucial parts for safe operation of reactor vessels in nuclear power plants, Crack initiation and propagation were reported in stud bolts that arc used for closure of reactor vessel and head, Stud bolts are inspected by ultrasonic technique during overhaul periodically for the prevention of stud bolt failure which could induce radioactive leakage from nuclear reactor, In conventional ultrasonic testing for inspection of stud bolts, cracks are detected by using shadow effect It takes too much time to inspect stud bolts by using conventional ultrasonic technique. In addition, there were numerous spurious signals reflected from every oblique surfaces of thread, In this study, the signal processing technique for enhancing conventional ultrasonic technique was introduced for inspecting stud bolts. The signal processing technique provides removing spurious signal reflected from every oblique surfaces of thread and enhances detectability of defects. Detectability for small crack was enhanced by using this signal processing in ultrasonic inspection of stud bolts in Nuclear Power Plants.

Dielectric properties of Pt/PVDF/Pt modified by low energy ion beam irradiation

  • Sung Han;Yoon, Ki-Hyun;Jung, Hyung-Jin;Koh, Seok-Keun
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 1999.07a
    • /
    • pp.110-110
    • /
    • 1999
  • Polyvinylidenefluoride (PVDF) is most used in piezoelectric polymer industry. Electrode effect on the electrical properties of PVDF has been investigated. al has been used due to fair adhesion for PVDF. Work function of metal plays an important role on the electrical properties of ferroelectrics for top and /or bottom electrode. However, Al has much lower work function than Pt or Au and so leakage current of Al/PVDF/Al may be large. Pt or Au has not been used for electrode of PVDF system due to poor adhesion. PVDF irradiated by Ar+ ion beam with O2 environment takes good adhesion to inert metal. Contact angle of PVDF to triple distilled water was reduced from 75$^{\circ}$ to 31$^{\circ}$ at 1$\times$1015 Ar+/cm2. Working pressure was 2.3$\times$10-4 Torr and base pressure was 5$\times$10-6 Torr. Pt was deposited by ion beam sputtering and thickness of pt film was about 1000$\AA$. in previous study, enhancing adhesion of Pt on PVDF was shown. in this study, effect of electrode on PVDF will be represented.

  • PDF

Intervention Effect on Reading Fluency for Children from Low-Income Families (저소득층 가정 아동의 읽기 유창성 중재 효과)

  • Yoon, Hyojin;Shin, Gayoung;Pae, Soyeong
    • Phonetics and Speech Sciences
    • /
    • v.6 no.4
    • /
    • pp.151-159
    • /
    • 2014
  • The study investigated the effects of reading intervention to enhance reading fluency for children from low-income families. The participants were 20 children from low-income families who are in grades 1 to 3. To qualify for participation in this study, all children had to score below 30 % ile on the Receptive vocabulary Test of the Expressive and Receptive Vocabulary Test or the Word reading fluency of the Korean Language-Based Reading Assessment. Participants were randomly assigned to the intervention (n=10) or control (n=10) group. The intervention group participated in the individualized intervention program using the guided repeated reading and the corrective feedback strategies. The results showed that participants in the intervention group performed better on reading fluency than those in the control group after participating in the intervention program. Specifically, guided repeated reading with corrective feedback strategies produced significant improvement on generalization to unpracticed passages as well as practiced passages. The results of this study suggest that guided repeated reading with corrective feedback is effective for enhancing reading fluency for children in Korea. Further study is needed in order to develop language-specific reading intervention.

The Effect of Action Observational Physical Training on Manual Dexterity in Stroke Patients (동작관찰훈련이 뇌졸중 환자의 손 조작능력에 미치는 영향)

  • Kim, Jong-Man;Yang, Byoung-Il;Lee, Moon-Kyu
    • Physical Therapy Korea
    • /
    • v.17 no.2
    • /
    • pp.17-24
    • /
    • 2010
  • The aim of this study was to determine the effect of action observational physical training (AOPT) on manual dexterity and corticomotor facilitation in stroke patients. Ten hemiparetic patients participated in this study. Each subject was asked to participate the three conditions; base condition (Base), physical training (PT), AOPT. Participants were asked to observe the action in the video that a therapist moved the blocks during the AOPT conditions. Corticomotor facilitation was determined in three conditions by monitoring changes in the amplitude of motor-evoked potentials (MEPs) elicited in hand muscles by transcranial magnetic stimulation. MEP responses were measured from the first dorsal interosseous after participants attended to three conditions. For the manual dexterity, Box and Block test (BBT) was used. The results of present study were summarized as follows: MEPs amplitude significantly tended to be larger than PT and Base condition. The scores of BBT in the AOPT condition were also significantly larger than other conditions. In conclusion, this finding of present study indicates that physical training for observation of an action is beneficial for enhancing a dexterity of paretic arm in stroke patients.

Combined Effect of Radiation and $7{\beta}$-Hydroxycholeslerol on Human Cervical Cancer Cells in vitro

  • Chae, Sung-Wook;Kang, Kyoung-Ah;Lee, Kyoung-Hwa;Zhang, Rui;Jung, Myung-Sun;Hyun, Jin-Won
    • Environmental Mutagens and Carcinogens
    • /
    • v.25 no.3
    • /
    • pp.104-109
    • /
    • 2005
  • [ $7{\beta}$ ]-Hydroxycholesterol (cholest-5-ene-3, 7-diol, $7{\beta}$-OHC) showed the cytotoxicity on human cervical carcinoma cells (HeLa), $10{\mu}M$ of 50% inhibitory concentration. We evaluated $7{\beta}$-OHC as the possibility of radiation sensitizer. The combination effect of $7{\beta}-OHC\;and\;{\gamma}$-irradiation was measured using colony forming assay and flow cytometer with propidium iodide and $DiOC_6$ stained cells, respectively. The combined treatment of $7{\beta}-OHC\;and\;{\gamma}$-irradiation did not show significant enhancing effects on HeLa cells.

  • PDF