• Korean Journal of Adult Nursing
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• v.29 no.3
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• pp.323-331
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• 2017

Purpose: The purpose of this study was to examine whether the uncertainty mediates relationship between rehabilitation motivation and social support. Methods: Participants were 123 adults patients diagnosed as stroke in a hospital located in a Metropolitan City. Data were collected by self-administered questionnaires measuring uncertainty, family support and medical team support as social support, rehabilitation motivation. Data were analyzed using t-test, one-way ANOVA, Pearson's correlation, and multiple regression analyses. The significance of mediating effect was analyzed by Sobel test. Results: Family support and uncertainty, respectively, were influential on rehabilitation motivation (${\beta}=.39$, p<.001, ${\beta}=-.18$, p=.011). Uncertainty showed partial mediating effect on relationship between family support and rehabilitation motivation, however, the effect was not significant (Z=1.63, p=.103). Conclusion: Interventions improving family support and decreasing uncertainty may be helpful in enhancing rehabilitation motivation.

• The Korean Journal of Emergency Medical Services
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• v.27 no.2
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• pp.65-78
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• 2023

Purpose: This study aimed to examine the mediating effect of self-efficacy between loneliness and life satisfaction among university students during the COVID-19 pandemic. Methods: This study administered a questionnaire survey of 282 college students enrolled in universities located in K area. Structural equation modeling analysis was utilized to examine the relationships of variables. The questionnaire included the life satisfaction, loneliness, and self-efficacy scales. Results: The results showed that loneliness had a negative correlation with life satisfaction and self-efficacy. Self-efficacy had a positive correlation with life satisfaction. The study confirmed that loneliness had a partial mediating effect on life satisfaction through self-efficacy. Conclusion: The study discussed ways of enhancing the life satisfaction of university students, the implications of the study findings, and suggestions for future research.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2022.11a
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• pp.163-164
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• 2022

Using the limestone powder as material that can substitute the clinker, it seems to get positive effect as filler and enhance workability of cement but the substitution amount and chemical properties of it can affect mechanical properties of cement. Thus, in this study, the effect limestone powder that has other properties on cement is evaluated. As a result, the workability enhancing effect was confirmed but deterioration of compressive strength was also checked. Later, with the view of workability, the experiment that the possibility of strength compensation by decreasing unit water weight of limestone powder cement is planned when the limestone powder is used.

• Journal of Korea Artificial Intelligence Association
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• v.2 no.1
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• pp.15-24
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• 2024

This study is about the effect of chatbot service quality on customer satisfaction and continuous use intention. Data collection was conducted for 13 days from October 23 to November 5, 2023, and a survey was conducted on customers who have used chatbot services. A total of 572 questionnaires were targeted, of which 545 valid data were used for analysis, excluding those that responded insincerely or did not meet the purpose of the study. The analysis results of this study are as follows: First, chatbot service quality partially had a significant effect on satisfaction. Second, customer satisfaction had a significant effect on continuous use intention. Therefore, in order to have a positive impact on continuous use intention, it is necessary to focus on marketing strategies related to chatbot service quality. Also, research focusing on data analysis and performance evaluation is crucial for enhancing chatbot services, necessitating studies that address real-time changes. Through sophisticated data analysis and variable measurement, chatbot services can be effectively improved, leading to enhanced customer satisfaction.

• Journal of Digital Convergence
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• v.14 no.10
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• pp.183-193
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• 2016

Recently, collaborations through MCS use in team projects are frequently conducted. This study developed a research model to examine the impact of collaboration through MCS on project performance. Team commitment and team trust regarded as the key drivers of enhancing project performance. Moreover, we also investigated the effect of usefulness of MCS on project performance. We posit ubiquity, polychronic use, and ease of use as the key antecedents of usefulness of MCS. The proposed theoretical framework was tested by using survey data collected from 116 university students who have rich experience with collaboration through MCS. PLS was employed for the analysis of the data. The analysis results showed that team trust significantly influences team commitment and project performance, respectively. However, usefulness of MCS is not significantly related to team commitment, while it play a prominent role in enhancing project performance. The results reveals that ease of use has a significant effect on usefulness of MCS, whereas ubiquity and polychronic use are not significantly related to it. From theoretical and practical perspective, this paper can provide in-depth knowledge of the effects of collaboration via MCS on project performance.

• Journal of Oral Medicine and Pain
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• v.21 no.1
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• pp.115-122
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• 1996

This study was performed to compare the anticarious effect of the different fluoride adsorbed(Naf, $NH_4F, Na_2PO_3F, SnF_2, TiF_4$) on synthetic hydroxyapatite and enamel. The amount of fluoride adsorbed in synthetic hydroxyapatite under various concentrations and pH of these fluoride solutions was measured by specific electrode. Enamel samples treated with 5 kinds of 1,000ppm fluoride solutions for 10 minutes were evaluated for fluoride uptake and enamel soubility. The results were as follows. 1. The adsorption of fluoride on synthetic hydroxyapatite increased gradually by the concentration of the fluoride solution, In 1,000ppm fluoride solution, the adsorption of fluoride on synthetic hydroxyapatite treated with NH4F and NaF solutions at pH 4.0 was relatively higher than that of other fluoride solutions. In NH4F and NaF solutions, the adsorption of fluoride on powdered enamel was higher at pH 4.0 solution than at pH 7.0 solution. 2. Fluoride uptake from NH4F solution was relatively high. But that from $Na_2PO_3F$ solution was lower than those from other fluoride solutions. 3. Fluoride solutions were significantly effective on enhancing acid resistance. $NH_4F$ solution was relatively more effective than others on enhancing acid resistance. 4. $SnF_2 and TiF_4$ solutions had the same effect on fluoride adsorption, fluoride uptake, and enamel solubility.

• Child Health Nursing Research
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• v.10 no.2
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• pp.153-164
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• 2004

The purpose of this study is to investigate the effect on mother-fetus attachment through mother-fetus interaction promotion program of talking and tactual stimulation aimed at enhancing sensitivity of primipara Non-equivalent control group posttest design was used. Fifty primiparas (26 mothers for intervention group and 24 mothers for control group) were recruited from three general hospital and an OBGY clinic located in Gang Nung city. Data was collected from January 30th to December 20th in 2001. For the intervention group, programed education which focused on mother-fetus interaction promotion of talking and tactile stimulation in the 1st trimester. Telephone counselling was provided with interval of two weeks. For two groups, home visiting for data collection of mother-fetus attachment was conducted at 36 to 38 weeks of gestational age. The data were analyzed using chi-square test and Fisher' Exact test to test the equivalence of two groups, and the effect of intervention program was determined with t- test. The result was as follow: The significant difference was found in mother-fetus attachment between two groups(t= 2.772, P= 0.0079). It indicated that intervention program was effective in improving mother-fetus attachment. In conclusion, this study has shown that the applied nursing intervention aimed at enhancing sensitivity of primiparas to fetus's movement promoted mother-fetus attachment. Therefore, this study suggests that this nursing intervention to increase maternal sensitivity to the fetus's movement should be broadly applied to primiparas, which can be beneficial for formation of mother-infant relationship, and for promotion of the social, affective, and cognitive developments of their children.

• Korean Journal of Pharmacognosy
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• v.42 no.1
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• pp.27-31
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• 2011

The ameliorating effect of the saponin rich fraction (SRF) prepared from the roots extract of Platycodon grandiflorum (Campanulaceae) on the scopolamine-induced cognitive dysfunction in mice were investigated by way of Moris water maze task. The mice with repeated oral administration of the SRF for four weeks showed markedly reduced the swimming time and swimming distance to reach the platform as well as the increase of number of crossing the platform on the Moris water maze task performed after scopolamine intoxication. The results suggest that SRF obtained from the roots extract of P. grandiflorum exert a cognitive enhancing effect on scopolamine-induced memory impairment in mice.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.1
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• pp.37-47
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• 2011

This study was aimed to investigate the memory enhancing effect of Jeongjihwan against scopolamine-induced amnesia in C57BL/6 mice. To determine the effect of Jeongjihwan on the memory and cognitive function, we have injected scopolamine (1 mg/kg, i.p.) into C57BL/6 mice 30 min before beginning of behavior tests. We have conducted Y-maze, Morris water-maze, passive avoidance and fear conditioning tests to compare learning and memory functions. Scopolamine-induced behavior changes of memory impairment were significantly restored by oral administration of Jeongjihwan (100 or 200 mg/kg/day). To elucidate the molecular mechanism underlying the memory enhancing effect of Jeongjihwan, we have examined the antioxidant defense system and neurotrophic factors. Jeongjihwan treatment attenuated intracellular accumulation of reactive oxygen species and up-regulated mRNA and protein expression of antioxidant enzymes as assessed by RT-PCR and western blot analysis, respectively. Jeongjihwan also increased protein levels of brain-derived neurotrophic factor (BDNF) compared with those in the scopolamine-treated group. Furthermore, as an upstream regulator, the activation of cAMP response element-binding protein (CREB) via phosphorylation was assessed by Western blot analysis. Jeongjihwan elevated the phosphorylation of CREB (p-CREB), which seemed to be mediated partly by extracellular signal-regulated kinase1/2 (ERK1/2) and protein kinase B/Akt. These findings suggest that Jeongjihwan may have preventive and therapeutic potential in the management of amnesia.

• Radiation Oncology Journal
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• v.34 no.3
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• pp.230-238
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• 2016

Purpose: Hypoxia can impair the therapeutic efficacy of radiotherapy (RT). Therefore, a new strategy is necessary for enhancing the response to RT. In this study, we investigated whether the combination of nanoparticles and RT is effective in eliminating the radioresistance of hypoxic tumors. Materials and Methods: Gold nanoparticles (GNPs) consisting of a silica core with a gold shell were used. CT26 colon cancer mouse model was developed to study whether the combination of RT and GNPs reduced hypoxia-induced radioresistance. Hypoxia inducible $factor-1{\alpha}$ ($HIF-1{\alpha}$) was used as a hypoxia marker. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining were conducted to evaluate cell death. Results: Hypoxic tumor cells had an impaired response to RT. GNPs combined with RT enhanced anti-tumor effect in hypoxic tumor compared with RT alone. The combination of GNPs and RT decreased tumor cell viability compare to RT alone in vitro. Under hypoxia, tumors treated with GNPs + RT showed a higher response than that shown by tumors treated with RT alone. When a reactive oxygen species (ROS) scavenger was added, the enhanced antitumor effect of GNPs + RT was diminished. Conclusion: In the present study, hypoxic tumors treated with GNPs + RT showed favorable responses, which might be attributable to the ROS production induced by GNPs + RT. Taken together, GNPs combined with RT seems to be potential modality for enhancing the response to RT in hypoxic tumors.