• Journal of Korean Society for Atmospheric Environment
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• v.24 no.3
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• pp.321-328
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• 2008

The number of patient with allergic asthma and atopy have increased in the cities of Korea steadily. In order to elucidate the primary factor, we investigated whether the house dust particles collected from an apartment of the middle classes has promoting effects of allergen-related airway inflammation and airway hyperresponsiveness. Mice were treated with 0.1 mL of 1 mg/mL of house dust particles suspension by intratracheal instillation once weekly for 10 weeks combined with ovalalbumin (OVA) sensitization. Intratracheal instillation of house dust particles and OVA sensitization caused an increase in the level of serum L-lactate dehydrogenase (LDH), immunoglobulun-E (IgE) and histamine, and an elevation in respiratory resistance. It also enhanced infiltration of eosinophils in the bronchoalveolar lavage fluid (BALF) of mice, IgE and eotaxin expression in blood, and T helper type 2 cell derived cytokine levels such as of interleukin (IL)-4, IL-13 and IL-5 in the BALF. However, it did not influence T helper type 1 cytokine such as interferon-gamma in the BALF. These results indicate that house dust particles elevate allergen-related airway inflammation and airway hyperresponsiveness in mice and may play an important role in the aggravation of asthma and atopy in Korea.

• Journal of Microbiology and Biotechnology
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• v.30 no.7
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• pp.1037-1043
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• 2020

Actinobacillus pleuropneumoniae (APP) is a causative agent of porcine pleuropneumonia. Therefore, the development of an effective vaccine for APP is necessary. Here, we optimized the culture medium and conditions to enhance the production yields of Apx toxins in APP serotype 1, 2, and 5 cultures. The use of Mycoplasma Broth Base (PPLO) medium improved both the quantity and quality of the harvested Apx toxins compared with Columbia Broth medium. Calcium chloride (CaCl₂) was first demonstrated as a stimulation factor for the production of Apx toxins in APP serotype 2 cultures. Cultivation of APP serotype 2 in PPLO medium supplemented with 10 ㎍/ml of nicotinamide adenine dinucleotide (NAD) and 20 mM CaCl₂ yielded the highest levels of Apx toxins. These findings suggest that the optimization of the culture medium and conditions increases the concentration of Apx toxins in the supernatants of APP serotype 1, 2, and 5 cultures and may be applied for the development of vaccines against APP infection.

• Proceedings of the Korea Contents Association Conference
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• 2006.05a
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• pp.193-198
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• 2006

Providing stable services has been a crucial factor to determine success or failure in current situations, in which online game industry has become one of the important industries. The study proposed a method of establishing a stable game servers using 'Hearbeat', one of the existing (load) balance server techniques for the enhancement of availability of online game servers. In the proposed method, one could provide users with stable game services, by inspecting master server frequently using stand-by servers corresponding to each game server.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.47 no.3
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• pp.302-312
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• 2014

This article describes the design and performance characteristics of a broadband ultrasonic mosaic transducer. We focus on the improved bandwidth in the high frequency band of a previously designed broadband ultrasonic transducer (Lee et al., 2014). The improvement in the pulse-echo bandwidth was achieved by employing twelve $2{\times}2$ element subarrays, operating at different resonance frequencies, and utilizing the mosaic array concept. We found that the -6 dB and -12 dB bandwidths of the newly developed broadband ultrasonic mosaic transducer, were up to 155% and 170% of the previously designed model, with a quality factor of 1.71 and 1.25, respectively. The averaged TVR (transmitting voltage response), SRT (receiving sensitivity), and FOM (figure of merit) values in a nearly flat transmitting response band, from 45 to 105 kHz providing a -12 dB bandwith of 60 kHz, were 163.3 dB (re $1{\mu}Pa/V$ at 1 m), -192.8 dB (re $1V/{\mu}Pa$), and -30.9 dB, respectively.

• The Korean Journal of Physiology and Pharmacology
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• v.6 no.6
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• pp.319-325
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• 2002

The induction of interleukin-6 (IL-6) using combined proinflammatory agents $(LPS/IFN-{\gamma}\;or\;TNF-{\alpha}/IFN-{\gamma})$ was studied in relation to p38 mitogen-activated protein kinase (MAPK) and $NF-{\kappa}B$ transcriptional factor in primary neonatal cardiomyocytes. When added to cultures of cardiomyocytes, the combined agents $(LPS/IFN-[\gamma}\;or\;TNF-{\alpha}/IFN-{\gamma})$ had stimulatory effect on the production of IL-6 and the elevation was significantly reduced by SB203580, a specific p38 MAPK inhibitor. SB203580 inhibited protein production and gene expression of IL-6 in a concentration-dependent manner. In this study, $IFN-{\gamma}$ enhancement of $TNF-{\alpha}-induced\;NF-{\kappa}B$ binding affinity as well as p38 MAP kinase activation was observed. However, a specific inhibitor of p38 MAPK, SB203580, had no effect on $TNF-{\alpha}/IFN-{\gamma}\;or\;LPS/IFN-{\gamma}-induced\;NF-{\kappa}B$ activation. This study strongly suggests that these pathways about $TNF-{\alpha}/IFN-{\gamma}$ or $LPS/IFN-{\gamma}-activated$ IL-6 release can be primarily dissociated in primary neonatal cardiomyocytes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.6A
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• pp.631-639
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• 2004

In this paper, we presented a new interference suppression method based on code grouping and groupwise decorrelation for multirate DS-CDMA downlink. The code grouping is accomplished according to the correlation property between the mother code and the child codes in OVSF code tree. Using groupwise decorrelation, the proposed receiver has relatively low computational complexity and does not require any information about interference users, such as code, data, and amplitude. From the simulation results in multipath channels, the proposed receiver is to provide significant performance enhancement.

• Korean Journal of Materials Research
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• v.16 no.5
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• pp.292-296
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• 2006

Effects of rapid thermal annealing of bismuth telluride thin films on their thermoelectric properties were investigated. Films with four different compositions were elaborated by co-sputtering of Bi and Te targets. Rapid thermal treatments in range of $300{\sim}400^{\circ}C$ were carried out during 10 minutes under the reducing atmosphere (Ar with 10% $H_2$). As the temperature of thermal treatment increased, carrier concentrations of films decreased while their mobilities increased. These changes were clearly observed for the films close to the stoichiometric composition. Rapid thermal treatment was found to be effective in improving the thermoelectric properties of $Bi_2Te_3$ films. Recrystallization of $Bi_2Te_3$ phase has caused the enhancement of thermoelectric properties, along with the decrease of the carrier concentration. Maximum values of Seebeck coefficient and power factor were obtained for the films treated at $400^{\circ}C$ (about $-128{\mu}V/K$ and $9{\times}10^{-4}\;W/K^2m$, respectively). With further higher temperature ($500^{\circ}C$), thermoelectric properties deteriorated due to the evaporation of Te element and subsequent disruption of film's structure.

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.05a
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• pp.66.2-66.2
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• 2011

A polymer-based multi-walled carbon nanotube (MWCNT) field emission device was fabricated from a composite dispersion of MWCNTs and waterborne polymethyl methacrylate (PMMA). The waterborne PMMA synthesized through the emulsion polymerization method was added to minimize the reagglomeration of dispersed MWCNTs with surfactants in water, and increase the adhesion between the and the substrate. The field emission properties of the fabricated device were optimized by adjusting the density of the emitter and the adhesion between the MWCNTs and the substrate. These were done by controlling the polymer concentration added to the MWCNT dispersion, as well as the amount of spray coating on the substrate. The results confirm the successful fabrication of a polymer-based MWCNT field emission device with a low field of 1.07 $V/{\mu}m$ and a good electric field enhancement factor of 2445. The device was fabricated by adding 0.8 mg/mL of polymer solution to the MWCNT dispersion and applying 20 cycles of spray coating. Application of this same MWCNT/polymer composite solution to a flexible polymer substrate also resulted in the successful fabrication of an electric field emission device with uniform emission and long time stability.

• Journal of Positioning, Navigation, and Timing
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• v.9 no.3
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• pp.183-189
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• 2020

In emergency rescue situations, the localization accuracy of the rescue requestor is a very important factor in determining the success or failure of the rescue. Indoors where Global Navigation Satellite System (GNSS) is not operated, there is no choice but to use Wi-Fi or LTE signals. However, the performance of the current emergency rescue system utilizing those RF signals is exceedingly low. In this study, the effectiveness of the surface correlation technology using the accumulated signal pattern of RF signals was verified in relation to the emergency localization technology. To validate the proposed system, we configured and tested an emergency rescue scenario in multi-floors building. When the emergency rescue was requested, it was confirmed that the initial localization error was large owing to the short length of the accumulated signal pattern. However, the localization error decreased over time, which eventually led to the accurate location information being delivered to the rescuer.

• Journal of ILASS-Korea
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• v.21 no.2
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• pp.111-115
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• 2016

This paper experimentally reports the effect of suspension stability on the thermal conductivity of water-based Au nanofluids. For this purpose, the water-based Au nanofluids are prepared by the one-step method called electro-chemical method with volume fraction of 0.0005%. The thermal conductivity of water-based Au nanofluids is measured from $22^{\circ}C$ to $42^{\circ}C$ using the transient hot wire method. To quantify the suspension stability of Au nanofluids, the suspension stability of nanofluids is evaluated using the in-house developed laser scattering system at a fixed wavelength of 632.8nm with the elapsed time. Based on the experimental results, the both thermal conductivity and suspension stability of water-based Au nanofluids are gradually decreased according to the time. These results experimentally show that the suspension stability of water-based Au nanofluids is the one of the important factor of thermal conductivity.