• The Journal of Engineering Geology
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• v.13 no.3
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• pp.359-368
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• 2003

A quarry is operated for filling-up the New Busan Harbor which is under construction, but actual rock quality is something different from the primary design. Therefore, object of this study is to classify whole rock quality for the quarry through site investigation and laboratory analyses because unexpected large amount of wasted rock is produced. For this object, various analyses were performed such as surveying, Schimidt Hammer test. joint spacing investigation and laboratory analyses using DIPS & RockWorks programs for evaluating joint sets and sizes of rock fragments after blasting. As a result, it is expected that large amount of wasted rock under ${\Phi}100mm$ is produced after blasting because of high joint density.

• Structural Engineering and Mechanics
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• v.65 no.6
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• pp.771-784
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• 2018

This study aims to investigate the stochastic response of isolated and non-isolated highway bridges subjected to spatially varying earthquake ground motion model. This model includes wave passage, incoherence and site response effects. The wave passage effect is examined by using various wave velocities. The incoherency effect is investigated by considering the Harichandran and Vanmarcke coherency model. The site response effect is considered by selecting homogeneous firm, medium and soft soil types where the bridge supports are constructed. The ground motion is described by power spectral density function and applied to each support point. Triple concave friction pendulum (TCFP) bearing which is more effective than other seismic isolation systems is used for seismic isolation. To implement seismic isolation procedure, TCFP bearing devices are placed at each of the support points of the deck. In the analysis, the bridge selected is a five-span featuring cast-in-place concrete box girder superstructure supported on reinforced concrete columns. Foundation supported highway bridge is regarded as three regions and compared its different situation in the stochastic analysis. The stochastic analyses results show that spatially varying ground motion has important effects on the stochastic response of the isolated and non-isolated bridges as long span structures.

• Journal of Microbiology and Biotechnology
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• v.25 no.9
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• pp.1417-1424
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• 2015

In this study, we tried to characterize Streptomyces peucetius CYP157C4 with homology modeling using three cytochrome P450 (CYP) structures (CYP157C1, CYP164A2, and CYP107L1), having discovered that CYP157C4 lacks the ExxR motif that was considered invariant in all CYPs. We used Discovery Studio 3.5 to build our model after first assessing the stereochemical quality and side-chain environment, and a 7-ethoxycoumarin substrate was docked into the final model. The model-substrate complex allowed us to identify functionally important residues and validate the active-site architecture. We found a distance of 4.56 Å between the 7-ethoxycoumarin and the active site of the heme, and cloning and an in vitro assay of the CYP157C4 showed the dealkylation of the substrate. Since the details regarding this group of CYP structures are still unknown, the findings of this study may provide elucidation to assist with future efforts to find a legitimate substrate.

• Journal of Microbiology and Biotechnology
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• v.9 no.1
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• pp.62-69
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• 1999

In order to investigate the critical amino acid residues involved in the catalytic activities of $\beta$-cyclodextrin glucanotransferase ($\beta$-CGTase) excreted by Bacillus firmus var. alkalophilus, the amino acid residues in $\beta$-CGTase were modified by various site-specific amino acid modifying reagents. The cyclizing and amylolytic activities of $\beta$-CGTase were all seriously reduced after treatment with Woodward's reagent K (WRK) modifying aspartic/glutamic acid, N-bromosuccinimde (NBS) modifying tryptophan, and diethylpyrocarbonate (DEPC) modifying histidine residues. The roles of tryptophan and histidine residues in $\beta$-CGTase were further investigated by measuring the protection effect of various substrates during chemical modification, comparing protein mobility in native and affinity polyacrylamide gel electrophoresis containing soluble starch, and comparing the $K_m$ and $V_{max}$ values of native and modified enzymes. Tryptophan residues were identified as affecting substrate-binding ability rather than influencing catalytic activities. On the other hand, histidine residues influenced catalytic ability rather than substrate-binding ability, plus histidine modification had an effect on shifting the optimum pH and pH stability.

• Environmental Engineering Research
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• v.20 no.4
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• pp.356-362
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• 2015

Many burial sites were constructed in a short time to prevent the rapid spread of foot and mouth disease in infected livestock carcasses in Korea. More than 4,700 carcass burial sites were constructed in 2011. Approximately seven million poultry and 3.5 million livestock, including cattle and swine, were buried on farmland. Some burial sites were suspected of leachate leakage and were excavated and carcasses redisposed in a bioaugmentation process. This study performed interviews in order to understand the economic issues related to carcass burial and redisposal. The internal data from local government and the assumption data from online sites were analyzed to evaluate the costs; the focus was on burial site construction. The results showed that the local government paid $4.7 and $10.9 per carcass for traditional burial and redisposal. The comparable costs shown online were $4.5. This study found that the standard operating procedures should be carried out to reduce environmental impact and avoid additional costs. We estimated that the cost could be reduced by the advance preparations of materials against the emergency situations such as catastrophe of epidemics. In addition, the innovative technology for the stabilization of carcasses should be established through a future study.

• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.846-848
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• 2007

Recently, the most of website is supporting RSS with increasing the interest regarding web 2.0. RSS-reader is collecting the contents of RSS formats which are provided from the various web site and it is software application that assist users easily to getting the last update of area of interest without visiting a corresponding web site. In this paper, we developed RSS reader through Ajax which is an asynchronous method, JSP/Servlet which is a dynamic scripting language. We made them support both RSS format 1.0 and 2.0. Additionally developed fluid Ajax based menus, categories and functions of user-friendliness.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.264-264
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• 2006

The nanoparticle-hydrogel complex as a new bone defect replacement matrix, which is composed of the nanoparticles for the sustained release of BMP and the hydrogel for filling the bone defect site and playing a role as a matrix where new bone can grow, is presented. In vivo evaluation of bone formation was characterized by soft X-ray, MT staining, and calcium assay, based on the rat calvarial critical size defect model. The effective bone regeneration was achieved by the BMP-2 loaded nanoparticles in fibrin gel, compare to bare fibrin gel, the nanoparticle-fibrin gel complex without BMP-2, or the BMP-2 in fibrin gel, in terms of the new bone area and the gray level in X-ray, the bone marrow are, and the calcium content in the initial defect site. These findings suggest that the BMP-2 loaded nanoparticle-fibrin gel complex can a promising candidate for a new bone defect replacement matrix.

• Journal of Construction Engineering and Project Management
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• v.3 no.3
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• pp.10-16
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• 2013

The annual expenditure on diesel oil and heavy oil in the construction sector is the second largest among all industrial sectors. According to the greenhouse reduction scheme of Korean Government, construction sector targeted 7.1% reduction by 2020. Although this target is not higher than other industrial sectors, it is not easy to achieve the reduction target without radical advance in technology, which cannot be expected to happen soon, considering the conservative characteristics of construction industry. Most researches on environmental issues focus on the issues related to energy saving matters during material production stage or maintenance stage, such as heating and insulation, and few deal with the issues directly related to the energy use in the construction sites. This research regards the operation of equipment for the on-site construction processes as a system and attempts to model the energy use processes related to the activities in construction sites, and provides simulation results of earth excavation and hauling processes. The result of this research is expected to aid construction planners estimating the time-based patterns of energy use and assessing greenhouse gas emission and to help selecting more energy efficient alternatives at the planning stage.

• Earthquakes and Structures
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• v.7 no.6
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• pp.1283-1301
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• 2014

Ground motion modification is extensively used in seismic design of civil infrastructure, especially where few or no recorded ground motions representative of the design scenario are available. A site in Los Angeles, California is used as a study site and 28 ground motions consistent with the design earthquake scenario are selected. The suite of 28 ground motions is scaled and modified in the time domain (TD) and frequency domain (FD) before being used as input to a bilinear SDOF system. The median structural responses to the suites of scaled, TD-modified, and FD-modified motions, along with ratios of he modified-to-scaled responses, are investigated for SDOF systems with different periods, strength ratios, and post-yield stiffness ratios. Overall, little difference (less than 20%) is observed in the peak structural accelerations, velocities, and displacements; displacement ductility; and absolute accelerations caused by the TD-modified and FD-modified motions when compared to the responses caused by the scaled motions. The energy absorbed by the system when the modified motions are used as input is more than 20% greater than when scaled motions are used as input. The observed trends in the structural response are predominantly the result of changes in the ground motion characteristics caused by modification.

• Earthquakes and Structures
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• v.15 no.4
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• pp.403-410
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• 2018

The choice of attenuation relationships is one of the most important parts of seismic hazard analysis as using a different attenuation relationship will cause significant differences in the final result, particularly in near distances. This problem is responsible for huge sensibilities of attenuation relationships which are used in seismic hazard analysis. For achieving this goal, attenuation relationships require a good compatibility with the target region. Many researchers have put substantial efforts in their studies of strong ground motion predictions, and each of them had an influence on the progress of attenuation relationships. In this study, two attenuation relationships are presented using seismic data of Mazandaran province in the north of Iran by Genetic Expression Programming (GEP) algorithm. Two site classifications of soil and rock were considered regarding the shear wave velocity of top 30 meters of site. The quantity of primary data was 93 records; 63 of them were recorded on rock and 30 of them recorded on soil. Due to the shortage of records, a regression technique had been used for increasing them. Through using this technique, 693 data had been created; 178 data for soil and 515 data for rock conditions. The Results of this study show the observed PGA values in the region have high correlation coefficients with the predicted values and can be used in seismic hazard analysis studies in the region.