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Incidence and Risk Factors for Diabetes Mellitus in Korean Middle-aged Men : Seoul Cohort DM Follow-up Study (우리나라 성인 남성 당뇨병의 발생양상과 위험요인에 관한 전향적 코호트 연구)

  • Kim, Dong-Hyun;Park, Sung-Woo;Choi, Moon-Gi;Kim, Dae-Sung;Lee, Moo-Song;Shin, Myung-Hee;Bae, Jong-Myon;Ahn, Yoon-Ok
    • Journal of Preventive Medicine and Public Health
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    • v.32 no.4
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    • pp.526-537
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    • 1999
  • Objectives : It is known that the prevalence of diabetes mellitus(DM) appears to be rapidly increasing in recent times in Korea, presumably due to a westernized diet and change of life style followed by rapid economic growth. Based on the Seoul male cohort which was constructed in 1993, this study was conducted to estimate the annual incidence rates of DM through 4 years' follow up and to determine which factors are associated with DM risk in Korean middle-aged men. Methods : Among 14,533 men recruited at baseline, 559 were excluded because they reported a history of diabetes or were found to be diabetes at 1992 routine health examination. During 4 years' follow-up, 237 incident DM cases were ascertained through chart reviews and telephone contacts for those who have ever visited hospitals or clinics under suspicion of DM during 1993-1996 and the biennial routine health examinations in 1994 and 1996. Results : In this study the annual incidence of DM among the study population was estimated to be 0.5 per 100. This study showed that fasting glucose level at initial baseline examination was a powerful predictor of risk for diabetes several years later(fasting blood glucose of $\geq$ 110 mg/dl compared with $\leq$ 80 mg/dl, Hazard Ratio[HR]:15.6, 95% Confidence interval[CI]=9.1-26.6) after considering potential covariates such as age, family history, smoking and alcohol history, body mass index, physical activity, total energy intake, and total fiber intake. Adjusted hazard ratios of family history of diabetes was 1.95(95% CI=1.38-2.75); of obesity as measured by BMI(BMI $\geq$ 25.3 compared with $\leq$ 21.3) was 7.19(95% CI=3,75-13.8); of weight change during middle life(>10kg compared with $\leq$ 5) was 1.77(95% CI=1.16-2.69); of smoking(current vs none) was 1.93(95% CI=1.06-3.51); and fat intake(upper fertile compared with lower fertile) was 1.88(95% CI=1.01-3.49), while fiber intake was associated with the reduced risk(HR=0.36, 95% CI=0.19-0.67). Conclusion : The factors identified in this study indicate that the greatest reduction in risk of diabetes might be achieved through population-based efforts that promote fiber intake and reduce obesity, smoking, and fat intake.

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Distribution of Organic Matter and $Al_o+1/2Fe_o$ Contents in Soils Using Principal Component and Multiple Regression Analysis in Jeju Island (주성분분석 및 다중회귀분석에 의한 제주도 토양유기물 및 $Al_o+1/2Fe_o$ 함량 분포)

  • Moon, Kyung-Hwan;Lim, Han-Cheol;Hyun, Hae-Nam
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.5
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    • pp.748-754
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    • 2010
  • The contents of soil organic matter (SOM) and $Al_o+1/2Fe_o$ in soils are important criteria for the classification of new Andisols in Soil Taxonomy system. There are many soil types in Jeju Island with various soil forming environments. This paper was conducted to estimate the contents of soil organic matter and the content of ammonium oxalate extracted Al and Fe ($Al_o+1/2Fe_o$) using various environmental variables and to make soil property maps using a statistical analyses. The soil samples were collected from 321 locations and analyzed to measure the contents of SOM and $Al_o+1/2Fe_o$. It was analyzed the relationships among them and various environmental variables such as temperature, precipitation, net primary product, radiation, evapotranspiration, altitude, soil forming energy, topographic wetness index, elevation, difference surrounded area, and distances from the shore and the peak. We can exclude multi-collinearity among environmental variables with principal component analysis and reduce all the variables to 3 principal components. The contents of SOM and $Al_o+1/2Fe_o$ were estimated by multiple regression models and maps of them were made using the models.

NIRS ANALYSIS OF MOLASSES AND EATS USED AT THE ANIMAL FEEDS INDUSTRY

  • Garrido-Varo, Ana;Perez-Marin, Maria Dolores;Gomez-Cabrera, Augusto;Guerrero-Ginel, Jose Emilio;Paz, Felix De;Delgado, Natividad
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1613-1613
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    • 2001
  • Fats and molasses are used, at the present time, in a considerable proportion as ingredients for the animal feed industry. They are mainly used as energy sources, but also they provide other characteristics of technological and nutritional interest (dust reduction, increase in palatability, etc). Both semi-liquid ingredients have numerous aspects in common from the point of view of their use in livestock feeds, as well as of their analytical control. Feed manufacturers use several criteria to evaluate the quality of fat and molasses. Furthermore, the traditional methods currently used, for their evaluation (eg. fatty acids, sugars, etc) are expensive and more sophisticated that the traditionally used for solid ingredients. The objective of the present work is to carry out a viability study to evaluate the ability of NIRS technology for the quality control of fat and molasses. Samples of liquid molasses (n = 42) and liquid fat ( n = 61), provided by a feed manufacturer, were scanned in a FOSS-NIR Systems 6500 monochromator equipped with a spinning module. The samples were analysed by folded transmission, using a sample cup of 0.1mm pathlength and gold surface reflector. For molasses, calibration equations were developed for the prediction of moisture (SECV=1.69%; $r^2$=0, 42), gross protein (SECV=0, 14%; $r^2$=0, 99), ashy (SECV=0, 60%; $r^2$=0, 84), NaCl (SECV=0, 05%; $r^2$=0, 99) and sugars (SECV=1, 04%; $r^2$=0, 86). For animal fats calibrations were obtained for the prediction of moisture (SECV=0, 14%, $r^2$=0, 88), acidity index (SECV=0, 83%, $r^2$=0, 82), MIU (SECV=0, 38%, $r^2$=0, 94) and unsaponifiables (SECV=0, 45%, $r^2$=0, 87). High accuracy calibration equations were also obtained for the prediction of the fatty acid profile. The equations have $r^2$values around 0.9 or highest. The results showed that NIRS technology could provide rapid and accurate results and reduce analytical costs associated to the quality control of two Important feed ingredients of a well known chemical variability.

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A Study on the Liberation Characteristics of Waste Concrete for Production of High Quality Recycled Aggregate (고품질(高品質) 순환골재(循環骨材) 생산(生産)을 위한 폐콘크리트의 단체분리(單體分離) 특성(特性) 연구(硏究))

  • Kim, Kwan-Ho;Mun, Myoung-Wook;Cho, Hee-Chan;Ahn, Ji-Whan
    • Resources Recycling
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    • v.19 no.3
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    • pp.52-61
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    • 2010
  • In general, the waste concrete is simply crushed and reused as a recycled aggregate at a low value application such as back filling material. It because that the quality of recycled aggregate is lower than one of natural aggregate due to the insufficient liberation of aggregate and cement mortar. So in this study, the liberation characteristics of liberation of aggregate and cement mortar is analyzed to investigate the limitation of conventional crushing stage at waste concrete processing circuit. In this process, thermal treatment method is evaluated for the enhancement of liberation. From test results, the preferential breakage along the grain boundary is not accomplished by the conventional crushers. It leads a low quality of recycled aggregate and a fracture of aggregate. To solve these problems, gentle breakage is used as a breakage mechanism to induce preferential breakage along the grain boundary. The recycled aggregate produced from the free fall test, which adopts a gentle breakage, shows a better liberation characteristics and a higher quality.

Assessment of the Hydraulic Conductivity of the Furnace Slag Coated with the Mixture of Bentonite-sepiolite-guargum under Sea Water Condition (벤토나이트-해포석-구아검 혼합물질이 코팅된 제강슬래그의 해수에 대한 투수성 평가)

  • Cheong, Eui-Seok;Rhee, Sung-Su;Woo, Hee-Soo;Park, Jun-Boum
    • Journal of Soil and Groundwater Environment
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    • v.16 no.4
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    • pp.1-9
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    • 2011
  • Bentonite has been generally used as vertical cutoff barrier material and reported to have several problems regarding its low workability, drying shrinkage cracking by particle cohesion, and ineffective waterproof ability under sea water condition. In this study, the particle sealant, the furnace slag coated by the mixture of bentonite, sepiolite and guargum, was developed to compensate these weak points and the hydraulic conductivity of the particle sealant was evaluated. Drying shrinkage cracking and swelling index was estimated to find the optimal mixing ratio of bentonite, sepiolite and guargum. The hydraulic conductivity of the particle sealants having different amount of sealant (bentonite-sepioliteguargum mixture) coating the furnace slag was estimated using the rigid wall permeameter and flexible wall permeameter. The results showed that drying shrinkage cracking was not found in the bentonite-sepiolite mixture with 20% sepiolite contents and the results from free swelling tests for the sealant having 1 : 0.025, 1 : 0.05 and 1 : 0.075 of weight ratios of bentonite-sepiolite mixture and guargum under simulated sea water condition were higher than those for the bentonitesepiolite mixture without guargum under tap water condition. These three sealants were coated on the furnace slag with 50% and 60% of sealant in the particle sealant and the hydraulic conductivity was estimated. In the cases of the particle sealants having 20% sepiolite in the bentonite-sepiolite mixture and 1 : 0.075 weight ratio of the bentonite-sepiolite mixture and guargum, the hydraulic conductivity from the rigid wall permeameter was below $1.0{\times}10^{-7}$ cm/sec under simulated sea water condition. The hydraulic conductivity of the particle sealant having $1.0{\times}10^{-6}$~$1.0{\times}10^{-7}$ cm/sec by the rigid wall permeameter was estimated using the flexible wall permeameter and found to be below $1.0{\times}10^{-7}$ cm/sec.

A Study on Estimation of Carotid Intima-Media Thickness(IMT) using Pulse Wave Velocity(PWV) (맥파전달속도를 이용한 내중막 두께 추정에 관한 연구)

  • Song, Sang-Ha;Jang, Seung-Jin;Kim, Wuon-Shik;Lee, Hyun-Sook;Yoon, Young-Ro
    • Journal of Biomedical Engineering Research
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    • v.30 no.5
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    • pp.401-411
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    • 2009
  • In this paper, we correct pulse wave velocity(PWV) with heart-rate and derive regression equations to estimate intima-media thickness(IMT). Widely used methods for diagnosis of arteriosclerosis are IMT and PWV. Arterial wall stiffness determines the degree of energy absorbed by the elastic aorta and its recoil in diastole but there is not correlation between sclerosis and IMT in an existing study. In this study, we will correct PWV with heart-rate and get regression equation to estimate IMT using heart-rate correction index(HCI). We executed experiments for this study. Made up question of physical condition and measured electrocardiogram(ECG), photoplethysmogram (PPG) of finger-tip and toe-tip and ultrasound image of carotid artery. Calculated PWV and IMT using ECG, PPG and ultrasound image. We found that every p-value between PWV and IMT is not significant(<0.05). But p-value between IMT and HCI which is a corrected PWV using heart-rate is significant(>0.01). We use HCI and various measured parameter for estimating regression equation and apply backward estimation to select parameters for regression analysis. Result of backward estimation, found that only HCI is possible to derive proper regression equation of IMT. Relationship between PWV and IMT is the second order. Result of regression equation of E-H PWV is $R^2$=0.735, adj $R^2$=0.711. This is the best correlation value. We calculate error of its analysis for verification of earlobe PWV regression equation. Its result is RMSEP=0.0328, MAPE(%) = 4.7622. Like this regression analysis, we know that HCI is useful parameter and relationship between PWV, HCI and IMT. In addition, we are able to suggest possibility which is that we can get different parameter of prediction throughout just one measurement.

Efficacy of Temporal Fixation Using Threaded Trans-Calcaneal Pin in Patients with Ankle Fracture-Dislocation or Tibia Pilon Fractures (발목 골절 및 탈구 혹은 경골 천정 골절 환자들의 수술에 있어 경종골핀을 이용한 발목 외고정 장치를 적용했을 때의 임상적 효용성)

  • Park, Dae-Hyun;Gwak, Heui-Chul;Kim, Jung-Han;Lee, Chang-Rak;Kwon, Yong-Uk;Choo, Hye-Jung;Park, Chul-Soon
    • Journal of Korean Foot and Ankle Society
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    • v.24 no.2
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    • pp.81-86
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    • 2020
  • Purpose: Ankle fractures with dislocations and pilon fractures at the distal tibia are usually associated with soft tissue damage caused by high-energy damage. Recently, a two-stage operation to perform internal fixation after the application of external fixation devices for stabilizing soft tissues has been accepted as the treatment of choice. This paper reports the clinical result of these injuries treated with threaded trans-calcaneal pin external fixation devices. Materials and Methods: Thirty-three patients diagnosed with ankle fractures with dislocations or tibial pilon fractures without open wounds. They underwent surgical treatment with threaded trans-calcaneal pin external fixation from January 2008 to February were enrolled in this study. This study evaluated the visual analogue scale (VAS), foot function index (FFI), and Olerud & Molander score as well as whether complications occurred. Results: The average VAS showed a meaningful decrease (p<0.001) from 7.4 before surgery to 2.6 after application of the external fixation device, and 1.4 at 12 months after surgery. The FFI also decreased significantly from 84.3 preoperatively to 20.3 at 12 months postoperatively (p<0.001). The Olerud & Molander score averaged 71.4 points, showing good clinical results. Complete bone union was observed in all patients. One patient each underwent debridement due to wound necrosis and infection in the pin insertion site. At the final follow-up, seven patients had posttraumatic ankle joint arthritis, according to a radiological examination. Conclusion: Manual reduction and external fixation using a threaded trans-calcaneal pin is a suitable surgical technique that is easy to perform and shows good clinical outcomes in stabilizing soft tissue damage in fractures and dislocations of ankle fracture or tibia pilon fractures in foot and ankle injury.

Effect of nutrition care process-based nutrition intervention on improvement of intake in the elderly in-patients with malnutrition (영양관리과정에 근거한 영양중재가 노인 영양불량 입원환자의 식사섭취량 증진에 미치는 효과)

  • Park, Ji-Hyun;Kang, Min-Ji;Seo, Jung-Sook
    • Journal of Nutrition and Health
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    • v.51 no.4
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    • pp.307-315
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    • 2018
  • Purpose: This study evaluated the effects of personalized nutrition intervention for increasing hospital meal intake by elderly patients with malnutrition. Methods: The subjects were 30 elderly patients with malnutrition who visited a general hospital located in Daegu. An individual nutrition intervention such as change of meal types or special meal service was given to the patients according to nutrition diagnosis related to inadequate intake of hospital meals. Nutritional intake status of the subjects was assessed by analyzing energy intake, protein intake, index of nutritional quality (INQ), nutrient adequacy ratio (NAR) and mean adequacy ratio (MAR). Results: The causes of inadequate intake in the subjects were poor appetite or preference problems (46.7%), symptom-related problems (30.0%) and mastication problems (23.3%). The INQ of protein in the subjects was significantly increased from $0.81{\pm}0.17$ to $1.41{\pm}0.25$ after the nutrition intervention (p < 0.05). The NAR of protein (before $0.50{\pm}0.21$, after $0.58{\pm}0.17$), iron (before $0.72{\pm}0.30$, after $0.84{\pm}0.29$) and vitamin $B_2$ (before $0.31{\pm}0.16$, after $0.37{\pm}0.14$) was also increased after the nutrition intervention (p < 0.05). The MAR of five nutrients, protein, calcium, iron, vitamin A and vitamin $B_2$, was significantly increased by the nutrition intervention (p < 0.05). Conclusion: Personalized nutrition intervention according to nutrition diagnosis related to inadequate intake of hospital meals may improve the intake amount of elderly patients with malnutrition.

Automatic Boundary Detection of Carotid Intima-Media based on Multiresolution Snake (다해상도 스네이크를 통한 경동맥 내막-중막 경계선 자동추출)

  • Lee, Yu-Bu;Choi, Yoo-Joo;Kim, Myoung-Hee
    • The KIPS Transactions:PartA
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    • v.14A no.2
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    • pp.77-84
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    • 2007
  • The intima media thickness(IMT) of the carotid artery from B mode ultrasound images has recently been proposed as the most useful index of individual atherosclerosis and can be used to predict major cardiovascular events. Ultrasonic measurements of the IMT are conventionally obtained by manually tracing interfaces between tissue layers. The drawbacks of this method are the inter and intra observer variability and its inefficiency. In this paper, we present a multiresolution snake method combined with the dynamic programming, which overcomes the various noises and sensitivity to initialization of conventional snake. First, an image pyramid is constructed using the Gaussian pyramid that maintains global edge information with smoothing in the images, and then the boundaries are automatically detected in the lowest resolution level by minimizing a cost function based on dynamic programming. The cost function includes cost terms which are representing image features and geometrical continuity of the vessel interfaces. Since the detected boundaries are selected as initial contour of the snake for the next level, this automated approach solves the problem of the initialization. Moreover, the proposed snake improves the problem of converging th the local minima by defining the external energy based on multiple image features. In this paper, our method has been validated by computing the correlation between manual and automatic measurements. This automated detection method has obtained more accurate and reproducible results than conventional edge detection by considering multiple image features.

A Study on the Change of Bone Mineral Density(BMD) by Life Habit and Physical Condition (성인의 신체조건 및 생활습관에 따른 골밀도 변화에 대한 연구)

  • Kim, Sun-Geun
    • Journal of radiological science and technology
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    • v.29 no.3
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    • pp.177-184
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    • 2006
  • Purpose: To evaluate the correlation between BMD and life habit such as drinking. exercise smoking or physical condition such as age, sex, height, weight, body mass index(BMI). Materials and Methods: I evaluated the BMD of the femoral neck and L2-L4 spines of 321 persons who took a regular health screening in Woosuk university oriental medical hospital from February to April in 2006 by dual energy bone mineral densitometry. Results: The age of persons ranged from 20 years to 75 years(mean $45.10{\pm}11.54$) and there were 160 males and 161 females. In males, BMD of the femoral head was highest at 2nd decade, BMD of the spine was highest at 4th decade, and BMD of both femoral head and lumbar spine was lowest at 6th decade. In fenales, BMD of both femoral head and lumbar spine was highest at 4th decade and lowest at 6th decade. Among the various physical conditions, only height of persons showed significant correlation with BMD in both males and females. BMD was increased according to increasing height. In males, BMD of persons who had habit such as drinking, exercise or smoking did not show significant change statistically. But in females, drinking group showed high BMD relative to non-drinking group in both femoral head and lumbar spine. Conclusion: BMD was different according to age, sex, height and life habit. Especially aged people showed osteoporotic change progressively. More persistent effort is needed to find out the factors decreasing BMD for prevention of problems by osteoporosis.

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