• 한방재활의학과학회지
• /
• 제27권4호
• /
• pp.85-96
• /
• 2017

Objectives To summarize and evaluate the efficacy of traditional Chinese herbal medicine (TCHM) treatment for antibiotic associated diarrhea (AAD). Methods Eight electronic databases were searched from their inception to August 2017. Randomized controlled trials (RCTs) assessing the efficacy of TCHM treatment for AAD were included. The risk of bias was assessed using the Cochrane risk of bias assessment tool. Data analysis was performed using RevMan software version 5.3. Results Seventeen RCTs involving 1138 patients with AAD were included for qualitative synthesis. TCHM treatment improved total effective rate (TER). However, the results that TER in experimental group was significantly higher than in control group were different between the included studies. TCHM enema treatment improved TER, but not significantly higher than control group. The most frequently used herbal formulas were Gamiwekwanjeon, Gamiinsampaedoksan, and Samryungbaekchulsan. The most frequently used TCHMs were Atractylodes macrocephala (Bai Zhu), Dioscorea batatas (Shan Yao). Within the studies documenting the adverse events, no serious adverse events associated with TCHM treatment were observed. Conclusions Evidence of TCHM treatment efficacy for AAD is encouraging, but not conclusive, because of the low methodological qualities, diversity of TCHM treatment prescriptions. Further well-designed RCTs with rigorous randomization and blinding method are needed to confirm these results.

• Advances in pediatric surgery
• /
• 제1권1호
• /
• pp.68-72
• /
• 1995

Segmental dilatation of the colon is a very rare disease entity of unknown etiology and may mimic Hirschsprung's disease. It is characterized by dilatation of a segment of the colon of variable length with obstruction due to lack of peristalsis in a normally innervated intestine. Recently authors experienced a case of segmental dilatation of the sigmoid colon in a 6 month-old male, who presented with severe constipation, abdominal distention, and abdominal mass since 2 months of age. Down's syndrome and congenital nystagmus were associated. Barium enema demonstrated focal dilatation of the sigmoid colon, but the rectum and descending colon proximal t o the affected colon were of normal caliber. Rectal suction biopsy with acetylcholinesterase staining was normal and anorectal manometry showed normal rectosphincteric reflex. At operation, there was a massively dilated and hypertrophied sigmoid colon with increased tortuous serosal vessels, measuring 15 cm in length and 10 cm in width. Teniae coli were identifiable in the affected segment. Frozen section biopsies at the proximal, affected, and distal colon showed ganglion cells. Descending loop colostomy was constructed initially and segmental resection and end to end colocolostomy were carried out 3 months later. Final histologic examination showed 1) normal colonic mucosa with ganglion cells, 2) prominent submucosal fibrosis and marked muscular hypertrophy, 3) unremarkable acetylcholinesterase activity and immunohistochemical findings against S-100 protein. On 8 months follow-up, he has been doing well and moves bowels 1-2 times daily.

• 한국융합학회논문지
• /
• 제8권5호
• /
• pp.223-231
• /
• 2017

본 연구는 핵심간호술 강화프로그램이 간호학생의 간호술 수행능력에 미치는 효과를 융합적으로 검증하여 간호학생의 수행능력을 증진시킬 수 있는 방안을 모색하고자 실시하였다. 첫 임상실습을 앞둔 간호학생을 대상으로 7개 핵심간호술(활력징후 측정, 경구투약, 근육주사, 피하주사, 단순도뇨, 배출관장, 비강캐뉼라를 이용한 산소요법)을 선정하여 2015년 1월 19일부터 23일까지 5일간 핵심간호술 강화프로그램을 실시하였다. 연구에 참여한 158명의 자료는 서술적 분석과 짝비교 검정을 이용하여 분석하였다. 연구결과, 핵심간호술 강화프로그램 후 간호학생의 간호술 수행능력 점수는 모두 유의하게 증가하였고 자신감과 문제해결능력에서 사전보다 사후 값이 통계적으로 유의하게 증가되었다. 또한 총 수행능력과 관련변수들 간에는 양의 상관관계가 있는 것으로 확인되어 프로그램이 간호학생의 간호술 수행능력 향상에 효과적인 것으로 나타났다.

• Tuberculosis and Respiratory Diseases
• /
• 제41권5호
• /
• pp.562-567
• /
• 1994

반지세포암은 과거에 여러 장기에서 보고되어졌으며 위에서 가장 많이 발생하며 드물게 대장, 직장, 담낭, 췌장, 유방, 전립선, 방광 그리고 요관 등에서 발생하는 것으로 알려져 있다. 폐에서 특히 작은 조직검사에서 반지세포가 나올 경우 일반적으로 전이에 의해 발생한 것으로 믿어져 왔다. 저자들의 경우 기관지경직시하 조직생검상 반지세포암으로 진단되었으며 다른 여러장기를 비침습적으로 조사한 결과 정상소견이어서, 원발성 폐의 반지세포암으로 추정되어 cisplatin과 etoposide의 복합 항암화학요법과 국소방사선조사를 시행하였으며 진단 후 176일째 급성호흡부전으로 사망하였다.

• 대한한방소아과학회지
• /
• 제30권4호
• /
• pp.99-110
• /
• 2016

Introduction Jaundice is one of the most common conditions found in neonatal period. Phototherapy is one of the main treatments for neonatal jaundice. However, several adverse effects of the phototherapy have been reported, including DNA damage recently. Therefore, a variety of treatments have been conducted to shorten the duration of phototherapy. Meanwhile, it has been hardly tried to prevent neonatal jaundice, but diverse approaches have been tried in traditional Chinese medicine (TCM) for many years. Therefore, this study aims to analyze the studies for the treatments to prevent neonatal jaundice based on TCM. Materials and Methods Various literatures have been searched via CNKI, and PubMed using the terms "neonatal jaundice" (新生儿黄疸, 胎黃, 胎疸) in category of 'Traditional Chinese Medicine', 'Traditional Chinese Medicinal Herbs' and 'Combination of Traditional Chinese Medicine With Western Medicine'. The search range included randomized controlled trials (RCTs), controlled clinical trials (CCTs), case reports, reviews and animal experiments published from 2013 to 2015. Results A total of 104 studies were found. 93 articles were excluded by reviewing the titles and abstracts. Out of the remaining 11 studies, 9 articles were RCTs, 2 articles were CCTs. The treatment used in neonatal babies in the studies were, using herbal remedies (meditation 5, bath 3 and retention enema 1) and the acupressure. All treatments were initiated within the first 24-48 hours after their birth. Then, there was a study that the subjects taken the herbal medicine were women during pregnancy. The outcome assessments used were the serum total bilirubin (TB), transcutaneous bilirubin measurement (TCB), the incidence of the hyperbilirubinemia, the duration time of the jaundice. Especially, TB, TCB and the incidence of the hyperbilirubinemia have decreased significantly more than that of the control group in the most of the results. No severe adverse events were reported in all articles reviewed. Conclusions Conventional treatment such as, herbal medicine in TCM, seems to be the effective way to prevent neonatal jaundice or hyperbilirubinemia. Therefore, the conventional treatment may be favorable choice for preventive treatment for neonatal jaundice.

• Journal of Yeungnam Medical Science
• /
• 제25권2호
• /
• pp.182-186
• /
• 2008

Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract that affects the large bowel. Its etiology remains controversial. However, an infectious or immunologic origin is considered the primary cause. The onset of UC is typically slow and insidious, but some patients may present acutely with symptoms mimicking infectious colitis. We report a case of ulcerative colitis mimicking acute hemorrhagic colitis at initial presentation. A 60-year-old man was referred to Yeungnam University Hospital for bloody diarrhea and abdominal pain. Sigmoidoscopy revealed mildly edematous mucosa in the rectum and hyperemic mucosa with petechiae in the sigmoid colon. The patient was treated with antibiotics for several days, and his symptoms improved. However, after one month, his bloody diarrhea relapsed. Follow-up sigmoidoscopy revealed mucosal friability in the rectum and sigmoid colon. He was diagnosed with ulcerative colitis, and his symptoms were improved with mesalazine and a steroid enema.

• 성인간호학회지
• /
• 제19권2호
• /
• pp.237-247
• /
• 2007

Purpose: This study was a randomized single-blind trial of whole versus split-dose PEG solutions for colonoscopy preparation to compare the patient compliance, quality of bowel cleansing, and endoscopist's satisfaction. Methods: The participants were recruited from outpatients who planned to receive colonoscopy of C hospital in Busan. Sixty participants were randomly assigned to receive either a spit-dose group(n=30) consuming $2{\ell}$ of PEG solution twice, or a whole-dose group(n=30), consuming $4{\ell}$ of PEG solution once. These participants completed the questionnaire to assess their compliance before colonoscopy. The quality of bowel cleansing was assessed using the Ottawa Scale with the endoscopist who was blinded to the type of preparation, and their satisfaction by using VAS. Results: The participants who did not completely consume $4{\ell}$ of PEG solution were less in split-dose than in whole-dose group (0% vs 13.3%). The split-dose group complained less about abdominal pain(t=2.644, p=0.009) and abdominal bloating(t=2.802, p=0.013) with a statistical significance. For the quality of bowel preparation, there were no significant differences in the bowel cleansing scores and the endoscopist's satisfaction between two groups. Conclusion: Colonic preparation with split-dose of PEG solution could be a more useful method for better patient compliance, with no significant impact on bowel cleansing quality.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제6권2호
• /
• pp.202-207
• /
• 2003

장신경 이형성증은 만성 가성 폐색 증후군의 드문 원인질환으로 임상 증상이 선천성 거대결장증과 유사하여 진단이 늦어지는 경우가 많기 때문에 임상적인 의심이 필요하다. 저자들은 쌍생아에서 신생아기에 태변이 배출되지 않고 복부 팽만을 보여 선천성 거대결장증이 의심되었으나 임상경과와 조직검사로 진단된 장신경 이형성증을 보고하는 바이다.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제10권1호
• /
• pp.81-85
• /
• 2007

소아와 청소년기에 발생하는 대장의 악성 종양은 매우 드물고 예후가 불량하다. 저자들은 내원 3개월 전부터의 식욕 부진, 체중 증가 지연과 내원 6일 전부터의 설사, 복통, 복부 종괴 촉지를 주소로 내원한 12세 남아에서 복부 초음파 촬영, 복부 전산화 단층 촬영, 바륨대장 조영술, 대장 내시경 검사 및 조직 검사 소견으로 진단된 S상 결장에 발생한 점액 선암종 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 한국임상수의학회지
• /
• 제31권5호
• /
• pp.454-456
• /
• 2014

9개월령 페르시안종 수컷 고양이(체중 3.2 kg)가 변비를 주증으로 내원하였다. 진단검사상 심한 변비와 거대 결장증이 확인되었다. 관장을 비롯한 즉각적인 응급처치를 실시한 후 신체검사를 실시하였고, 검사결과 음경구 0.5 cm 복측에서 비정상적인 요도구를 확인하였다. 이 요도구를 통해 3.5 fr tomcat catheter를 방광내부를 쉽게 삽입할 수 있었다. 영상진단과 신체검사를 통해 본 증례는 요도밑 열림증으로 진단되었다. 본 고양이는 중성화 수술과 함께 변비에 대한 내과적 처치가 실시되었다. 본 증례는 우리나라에서 처음으로 보고되는 만성 변비를 동반한 고양이의 요도밑 열림증이다.