• Title/Summary/Keyword: endometrium

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Treatment of Ednometrial Carcinoma Stage II

  • Han I.;Kanellitsas C.;Kumar N.;Amendola B.;Morley G.
    • Radiation Oncology Journal
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    • v.2 no.2
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    • pp.253-260
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    • 1984
  • Between January 1971 and December 1580 fifteen patients diagnosed of adenocarcinoma of the endometrium, stage II seen and treated at the University of Michigan Hospitals. are reviewed. Ten patients were treated with radiation therapy alone. five received hysterectomy after radiation. The five year survival of the patients receiving radiation and surgery was $100\%$ although one of them died after 62 month aster treatment. Of those receiving radiotherapy alone two died at i and 24months after therapy. All of the patients died of distant metastasis. Radiation cystitis was observed among surgically treated patients. while proctitis was observed in 3 cases receiving radiation alone. Though the number of cases reported is small due to rarity of the disease. it appears that radiation alone could provide reasonable tumor control. Also it appears that preoperative irradiation might lead to a longer survival. One patient who survived 62 months had para-aortic node involvement.

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Alcohol Consumption and Risk of Cancer: a Systematic Literature Review

  • de Menezes, Raquel Ferreira;Bergmann, Anke;Thuler, Luiz Claudio Santos
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.4965-4972
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    • 2013
  • This study aimed to discuss the consumption of alcohol as a risk factor for major cancers. We performed a search in the PubMed database, using the following inclusion criteria: meta-analysis published in English in the last 10 years that addressed the relationship between alcohol and the risk of developing cancer. The results indicate that moderate to heavy consumption of alcohol increases the risk of developing cancer of the oral cavity and pharynx, esophagus, stomach, larynx, colorectum, central nervous system, pancreas, breast and prostate. This review did not find any association between alcohol consumption and an increased risk of cancers of the lung, bladder, endometrium and ovary. It was also observed that alcohol consumption may be inversely related to thyroid cancer. Our systematic review has confirmed consumption of alcohol as a risk factor for the development of several types of cancer.

Histological Changes of the Ovary and the Uterus of Guinea pigs Administerd Radioiodine (방사성옥소(131I)가 Guinea pig의 난소조직과 자궁조직에 미치는 영향)

  • Lee, Heung Shik;Lee, Kang Wook;Shin, Kwang Soon
    • Korean Journal of Veterinary Research
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    • v.13 no.1
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    • pp.1-4
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    • 1973
  • This experiment was performed in order to investigate the effect of radioiodine upon the uterus and the ovary of guinea pigs. The animals were injected single dose of 4. 5 mCi of radioiodine per kg of body weight. They were sacrificed on various time intervals; 1, 7, 14, 28, 42 and 56 days after the injection. The results were as follows: 1. In the ovary, the follicle cells and the ova were degenerated with lapse of time after the injection. 2. In the uterus, hyperplasia of the lamina propria of the endometrium and atrophy of the myometrium were observed in accordance with time after the injection.

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A rare pseudomyxoma peritonei with a MSH2 variation of unknown significance and two mutation carrier family members

  • Kim, Yoo Min;Kim, Min Kyu
    • Journal of Genetic Medicine
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    • v.13 no.1
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    • pp.55-58
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    • 2016
  • Pseudomyxoma peritonei (PMP) is a rare tumor that usually originates in the appendix, but a small number of cases originate in the ovary. Lynch syndrome (LS) is an autosomal dominant hereditary condition that increases the risk of cancer, particularly in the colon and endometrium. Mutations in the mismatch repair genes (MSH2, MLH1, MSH6, and PMS2) increase the risk of LS. Reported PMP cases with hereditary gene mutations of unknown significance are also rare. Here, we investigated a PMP patient and her family members, who have an MSH2 variant of unknown significance. Physicians have an important role in counseling, management, and surveillance based on genetics and pathogenicity.

Ultrasonographic Evaluation of the Normal Porcine Postpartum Uterus (분만 모돈에서 자궁의 초음파상 평가)

  • 이재영;강성수;김일화;최석화
    • Journal of Veterinary Clinics
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    • v.17 no.2
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    • pp.416-419
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    • 2000
  • Ultrasonographic appearance of the normal involution process of the porcine postpartum uterus was examined. Six, sows were used to determine the normal Ultrasonographic appearance of the involution postpartum uterus. Ultrasonographic examinations were performed daily from days one through eight, then on days 15 and 21 postpartum. Ultrasonographic the mean local uterine wall thickness was 12.00 mm on day one postpartum. By day 15 the mean total uterine wall thickness was about 7.21 mm and on day 21 postpartum the uterus was about 6.12 mm. From one day to five days postpartum, intraluminal contents were isoechoic to the endometrium. From 15 days to 21 days, the luminal 7ont7llts were of mixed echogenicity compared to the endometrillm.

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A Review of Mechanisms of Implantation

  • Kim, Su-Mi;Kim, Jong-Soo
    • Development and Reproduction
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    • v.21 no.4
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    • pp.351-359
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    • 2017
  • Implantation is a highly organized process that involves an interaction between a receptive uterus and a competent blastocyst. In humans, natural fecundity suggests that the chance of conception per cycle is relatively low (~30%) and two-third of lost pregnancies occur because of implantation failure. Defective implantation leads to adverse pregnancy outcomes including infertility, spontaneous miscarriage, intrauterine fetal growth restriction and preeclampsia. With use of advanced scientific technologies, gene expression analysis and genetically-engineered animal models have revealed critical cellular networks and molecular pathways. But, because of ethical restrictions and the lack of a mechanistic experiment, comprehensive steps in human implantation have still not been completely understood. This review primarily focuses on the recent advances in mechanisms of implantation. Because infertility is an emerging issue these days, gaining an understanding the molecular and hormonal signaling pathway will improve the outcome of natural pregnancy and assisted reproductive technology.

Study on the VEGF Gene Expression and the Role of PMSG Hormone in the Development of Endometrial Cancer in Mice

  • Kim, Sang-Hwan;Jung, Na-Hyeon;Oh, Min-Gee;Yoon, Jong-Taek
    • Journal of Animal Reproduction and Biotechnology
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    • v.35 no.1
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    • pp.35-41
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    • 2020
  • In this study, we investigated whether infusion of colorectal cancer cell line and PMSG could increase endometrial cancer. As a result, our study confirmed that the injection of colorectal cancer can cause inflammation and cancer in the uterus and increase the VEGF gene in the uterus. The study also found that endometrial cancer was associated with PMSG.

Two Cases of Oriental Medicine on Premature Ovarian Failure by Checking Ultrasonography and Serum Hormone Assay (초음파기기를 통한 장부형상 및 호르몬검사로 확인한 조기난소부전 환자 치험 2례)

  • Koh, Ji-Eun;Lyou, Myung-Sook
    • The Journal of Korean Obstetrics and Gynecology
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    • v.29 no.1
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    • pp.116-126
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    • 2016
  • Objectives: The purpose of these cases is to report the effects of oriental medicine on two patients with premature ovarian failure. Methods: Two patients who had amenorrhea and hot flashes caused by premature ovarian failure were treated by oriental medicine such as herb medication. We estimated the effects of treatments by follow-up measurements of serum hormone level, menstrual cycle and symptoms. Besides, follicle and endometrium were checked by ultrasonography for academic research.Results After treatments, their symptoms of premature ovarian failure were improved and the menstrual cycle resumed. And the level of serum Follicle Stimulating Hormone decreased and the level of serum E2 increased.Conclusions Two cases shows that oriental medicine has effects on patients with premature ovarian failure by follow-up measurements of serum hormone level, menstrual cycle and symptoms.

A Case of Cavitated Uterine Mass from Müllerian duct in a Mixed Breed Dog

  • Park, Chul-Ho;Son, Chang-Ho
    • Journal of Veterinary Clinics
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    • v.35 no.6
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    • pp.279-281
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    • 2018
  • This report describes a case of newly recognized congenital $M{\ddot{u}}llerian$ duct anomaly in a bitch. A fourteen-year-old, mixed breed bitch was presented with mild hematuria and mammary gland tumor. Complementary examinations were performed and abdominal ultrasonography revealed distended uterine horns and uterine tumor-like mass around the right ovarian area. Macroscopic examination showed the mass to be on the level of insertion of the right round ligament. The mass was cystic in nature, and had no communication with the uterine cavity. Histopathologically, the mass was identified as an accessory cavity lined by functional endometrium, which confirmed the diagnosis of accessory and cavitated uterine mass.

A Case Report of Endometrial Cancer Patient after Laparotomy Treated by Korean Medicine (자궁내막암 환자의 외과적 수술 이후 발생한 후유증에 대한 한방치험 1례)

  • Ko, Eun-Bi;Jang, Kwon-Jun;Yoon, Min-Ji;Lee, Ji-Yoon;Yang, Jung-Min;Oh, Jae-Sung
    • The Journal of Korean Obstetrics and Gynecology
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    • v.34 no.4
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    • pp.151-162
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    • 2021
  • Objectives: The purpose of this study is to report the effect of Korean medicine on endometrial cancer patient after laparotomy. Methods: The patient with endometrial cancer who underwent Total Abdominal Hysterectomy (TAH), Bilateral Salpingo Oophorectomy (BSO), Bilateral Paraaortic Lymph Node Dissection (BPLND) was treated by Korean medicine such as herbal medicine, acupuncture, moxibustion. To evaluate the patient, symptoms were measured by Numeric Rating Scale (NRS) and Eastern Cooperative Oncology Group (ECOG). Blood tests including cancer biomarker were conducted during treatment. Results: After treatment, postoperative pain and general weakness were gradually relieved. Conclusions: This case provides us treatment with Korean medicine have substantial benefit on postoperative complications after laparotomy.