• 제목/요약/키워드: emission computed

검색결과 456건 처리시간 0.028초

The Unnecessity of Positron Emission Tomography Computed Tomography in the Etiologic Evaluation of Neurodevelopmental Delay in Craniosynostosis Patients

  • Yang, Chae Eun;Park, Eun Kyung;Lee, Myung Chul;Shim, Kyu Won;Kim, Yong Oock
    • 대한두개안면성형외과학회지
    • /
    • 제18권1호
    • /
    • pp.21-24
    • /
    • 2017
  • Background: In evaluation of craniosynostosis patients in terms of neurodevelopmental delay, positron emission tomography computed tomography (PET-CT) scan can be used to assess brain abnormalities through glucose metabolism. We aimed to determine the unnecessity of PET-CT in this study. Methods: Thirty-eight patients diagnosed with craniosynostosis who underwent distraction osteogenesis from October, 2010 to November, 2013 were reviewed. Magnetic resonance imaging (MRI) and PET-CT scan were carried out for evaluation of the brain structure and function, whereas X-ray and CT scan were taken for evaluation of the skull. Results: Nine patients reported abnormal MRI findings which were not significant, and five patients showed local problem on brain on PET-CT scan. No correlation was found among them. Conclusion: PET-CT evaluation of possible abnormal brain findings do not affect surgical planning or require additional therapy. Preoperative PET-CT scan is not the essential study to get any etiologic information of the disease consequences or to establish the treatment plan.

Use of positron emission tomography-computed tomography to predict axillary metastasis in patients with triple-negative breast cancer

  • Youm, Jung Hyun;Chung, Yoona;Yang, You Jung;Han, Sang Ah;Song, Jeong Yoon
    • 대한종양외과학회지
    • /
    • 제14권2호
    • /
    • pp.135-141
    • /
    • 2018
  • Purpose: Axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB) are important for staging of patients with node-positive breast cancer. However, these can be avoided in select micrometastatic diseases, preventing postoperative complications. The present study evaluated the ability of axillary lymph node maximum standardized uptake value (SUVmax) on positron emission tomography-computed tomography (PET-CT) to predict axillary metastasis of breast cancer. Methods: The records of invasive breast cancer patients who underwent pretreatment (surgery and/or chemotherapy) PET-CT between January 2006 and December 2014 were reviewed. ALNs were preoperatively evaluated by PET-CT. Lymph nodes were dissected by SLNB or ALND. SUVmax was measured in both the axillary lymph node and primary tumor. Student t-test and chi-square test were used to analyze sensitivity and specificity. Receiver operating characteristic (ROC) and area under the ROC curve (AUC) analyses were performed. Results: SUV-tumor (SUV-T) and SUV-lymph node (SUV-LN) were significantly higher in the triple-negative breast cancer (TNBC) group than in other groups (SUV-T: 5.99, P<0.01; SUV-LN: 1.29, P=0.014). The sensitivity (0.881) and accuracy (0.804) for initial ALN staging were higher in fine needle aspiration+PET-CT than in other methods. For PET-CT alone, the subtype with the highest sensitivity (0.870) and negative predictive value (0.917) was TNBC. The AUC for SUV-LN was greatest in TNBC (0.797). Conclusion: The characteristics of SUV-T and SUV-LN differed according to immunohistochemistry subtype. Compared to other subtypes, the true positivity of axillary metastasis on PET-CT was highest in TNBC. These findings could help tailor management for therapeutic and diagnostic purposes.

Positron Emission Tomography/Computed tomography를 이용한 개 림프종의 영상 평가 (Positron Emission Tomography/Computed Tomography Features of Canine Lymphoma)

  • 박승조;권성영;민정준;최지혜
    • 한국임상수의학회지
    • /
    • 제33권1호
    • /
    • pp.51-57
    • /
    • 2016
  • In this study, the features of canine lymphoma on fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) were evaluated in three small breed dogs. In case 1, ultrasonography and CT indicated neoplastic involvement of the sternal, right axillary, submandibular, lower cervical, tracheobronchial, mesenteric, and sublumbar lymph nodes; spleen; and liver. However, intense FDG uptake on PET/CT images was detected only for the lymph nodes and spleen. No FDG uptake by the liver was detected for case 1 despite the confirmation of lymphoma by cytology. In case 2, ultrasonography and CT indicated neoplastic involvement of the axillary, mesenteric, and sublumbar lymph nodes and the spleen, while intense FDG uptake on PET/CT images was detected for the axillary and a few mesenteric lymph nodes, and the spleen. FDG uptake was additionally observed from popliteal lymph nodes, however there was no uptake by the sublumbar lymph nodes and some mesenteric lymph nodes. In case 3, neoplastic changes in the splenic, mesenteric, and sublumbar lymph nodes and spleen were suspected on ultrasonography, and lower cervical and popliteal lymph node involvements were additionally detected on PET/CT. Compared to ultrasonography, repeated PET/CT showed increased FDG uptake by the lymph nodes at an earlier stage after chemotherapy in case 3. This study illustrated the features of PET/CT in canine lymphomas and compared those to ultrasonography and CT findings. FDG uptakes were not detected from some lesions which were suspected to be neoplastic involvement in case 1 and 2. We could not clearly explain the reason of this result in the present study because cytological or histological examination was not performed for lesions that showed different results on ultrasonography, CT, and PET/CT. Further studies on the subclassification of canine lymphoma and the sensitivity and specificity of PET/CT for the detection of canine lymphoma are required. PET/CT data can provide useful information for predicting the therapeutic response at an early stage after treatment.

도파민 운반체 영상의 임상이용을 위한 실제적 접근 (Practical Approach for the Clinical Use of Dopamine Transporter Imaging)

  • 김재승
    • Nuclear Medicine and Molecular Imaging
    • /
    • 제42권6호
    • /
    • pp.425-434
    • /
    • 2008
  • Dopamine transporter imaging is useful in the diagnosis of Parkinson's disease and the most successful technique in the clinical use of neuroreceptor imaging. Recently, several radiopharmaceuticals including I-123 FP-CIT, Tc-99m TRODAT, and F-18 FP-CIT for dopamine transporter imaging have been approved for the routine clinical use in several European countries, Taiwan and Korea, respectively. This review summarized the practical issue for the routine clinical examination of dopamine transporter imaging.

Effects of Surface Termination on Directional Emission from Photonic Crystal Waveguides

  • Chung, K.B.
    • Journal of the Optical Society of Korea
    • /
    • 제12권1호
    • /
    • pp.13-18
    • /
    • 2008
  • We numerically investigate by the finite-difference time-domain method the effects of surface termination on directional emission exiting a photonic crystal waveguide. The directed power and far-field beam profile for the original proposal [E. Moreno et al., Phys. Rev. B 69, 121402 (2004)] and its enhancement [S. K. Morrison et al., Appl. Phys. Lett. 86, 081110 (2005)] are computed for different values of some important parameters. We find another surface termination condition with a positive surface displacement in the structure of the original proposal which has a negative surface displacement. Our surface termination is more effective than the original structure, and nearly as effective as the termination for the enhancement, for directional emission. Besides, our termination is simpler than that for the enhancement. We confirm the effectiveness of directional emission from our termination in its far-field beam profile, radiation intensity distribution, and additionally the wave-vector space representation by the Fourier analysis.

Early-Phase SPECT/CT for Diagnosing Osteomyelitis: A Retrospective Pilot Study

  • Soo Jin Lee;Kyoung Sook Won;Hyung Jin Choi;Yun Young Choi
    • Korean Journal of Radiology
    • /
    • 제22권4호
    • /
    • pp.604-611
    • /
    • 2021
  • Objective: The aim of this pilot study was to investigate the potential of early-phase single-photon emission computed tomography (SPECT)/computed tomography (CT) using technetium-99m methyl diphosphonate (99mTc-MDP) for diagnosing osteomyelitis (OM). Materials and Methods: Twenty-one patients with suspected OM were enrolled retrospectively. Three-phase bone scan (TPBS), early-phase SPECT/CT (immediately after blood pool planar imaging), and delayed-phase SPECT/CT (immediately after delayed planar imaging) were performed. The final diagnoses were established through surgery or clinical follow-up for over 6 months. We compared three diagnostic criteria based on (I) TPBS alone, (II) combined TPBS and delayed-phase SPECT/CT, and (III) early-phase SPECT/CT alone. Results: OM was diagnosed in 11 of 21 patients (nine surgically and two clinically). Of the 11 OM patients, criterion-I, criterion-II, and criterion-III were positive in six, seven, and 10 patients, respectively. Of the 10 non-OM patients, criterion-I, criterion-II, and criterion-III were negative in five, five, and seven patients, respectively. The sensitivity/specificity/accuracy of criterion-I, criterion-II, and criterion-III for diagnosing OM were 54.5%/50.0%/55.0%, 63.6%/50.0%/57.1%, and 90.9%/70.0%/87.5%, respectively. Conclusion: This pilot study demonstrated the potential of using the early-phase SPECT/CT to diagnose OM. Based on the results, prospective studies with a larger sample size should be conducted to confirm the efficacy of early-phase SPECT/CT.

단층진단법을 이용한 축대칭 부분예혼합 화염의 자발광 스펙트럼 해석에 관한 연구 (Tomographic Interpretations of Visible Emissions from the Axisymmetric Partially Premixed Flames)

  • 하광순;최상민
    • 대한기계학회논문집B
    • /
    • 제24권6호
    • /
    • pp.769-776
    • /
    • 2000
  • Visible spectral characteristics of cross-sectional emissions from a partially premixed methane/air and propane/air flames have been investigated. An optical train with a two-axis scanning mirror system was used to record line-of-sight emission spectra from 354nm to 618nm, and inversion technique was adapted to obtain cross-sectional emission spectra. By analyzing the reconstructed emission spectra, cross-sectional intensities of CH and $C_2$ radicals were separated from the background emissions. The blue flame edge and yellow flame edge were also obtained by image processing technique for edge detection with color photograph of flame. These edges were compared with radial distributions of CH, $C_2$ radicals and background emissions. The CH radicals were observed at blue flame edge. The background emissions were generated by soot precursor at upstream of flame and by soot at downstream of flame. The $C_2$ radicals in propane/air flame were observed more than those in methane/air flame.

난지도지역의 수은배출특성 연구: 배출공 내부의 농도와 배출공을 통한 수은플럭스의 관측 (Studies of Hg Concentrations and Fluxes in the Ventpipes Determined from a Large Landfill Site)

  • 김민영;김기현;조석주
    • 한국대기환경학회지
    • /
    • 제17권4호
    • /
    • pp.299-312
    • /
    • 2001
  • The analysis of vent -emitted Hg concentrations and relevant environmental parameters was made from the inlet of 42 ventpipes in Nan-Ji-Do area of Seoul during September/october of 2000. Using these data, the fluxes of Hg from the ventpipes were also derived. The mean concentration of Hg, computed using the data sets collected from 42 ventpipes, was 420$\pm$619ng m$^{-3}$ with the range of 3.45~2,952ng m$^{-3}$ . Because of large differences in concentration levels between two sectors 1 and 2 and between plain and slope areas. evaluation of the data was made by dividing them into four different categories such as plain areas of sectors 1 and 2 (and/or slope areas of sectors 1 and 2). When this classification was applied, the computed fluxes were highly different among each group with the generally enhanced fluxes in plain area relative to slope area. The computed fluxes were then used to make comparative analysis of different source processes in the study area.

  • PDF