• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7289-7294
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• 2013

We here document discovery of a new and simple model of tumor seeding involving the mouse peritoneum. Irradiated tumor cells administered by i.p. injection provided effective vaccination against peritoneal carcinomatosis and distal metastasis with colorectal carcinomas. In flow cytometric analysis, CD4+ and CD8+ T lymphocytes, macrophages and myeloid-derived suppressor cells (MDSCs), which are easy to obtain in the peritoneal cavity, were revealed to have significant differences between immunized and non-immunized mice and these contributed to antitumor responses. We also observed that both serum and peritoneal lavage fluid harvested from immunized mice showed the presence of CT26-specific autoantibodies. In addition, increase in level of TGF-${\beta}1$ and IL-10 in serum but a decrease of TGF-${\beta}1$ in peritoneum was found. Taken together, these findings may provide a new vaccine strategy for the prevention of peritoneal and even systemic metastasis of carcinomas through induction of an autoimmune response in the peritoneum.

• Journal of the Korean Society of Safety
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• v.33 no.3
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• pp.65-70
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• 2018

Terrain data for disaster analysis in hazardous or disaster areas is not only important but also needs to be built quickly. In particular, the introduction of drones is in the early stages of research using drones in a variety of fields such as shooting, analyzing and managing hazardous areas. It is expected that drone will be faster, safer and more effective than existing data collection method in case of small scale disaster hazard area and disaster area where equipment or manpower input is difficult. Therefore, in this study, drone shooting was performed for hazardous areas in mountainous roads located in Samcheok city, Gangwon province, and ground reference points were measured by RTK-GPS. The measured data were converted into DSM (Digital Surface Model) data by coordinate correction using Pix4D postprocessing program and then applied to the analysis of the hazard area of mountainous area. As a result, it was shown that it is effective to identify the risk by using the basic terrain data obtained from the drones.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.25 no.3
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• pp.121-127
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• 2014

Recently, local governments and suicide prevention centers have been trying to implement psychological autopsy. This effort has focused on adult suicide so far ; however, there are some difficulties in its application to adolescent suicide. Therefore, in this study, psychological autopsy studies of Korea were reviewed, and a methodology for adolescents' psychological autopsy was suggested. For the effective performance of the psychological autopsy in adolescent suicide, cooperation with each area of the government and implementation of bodies is necessary. In addition, the central system, which disseminates the standardized interview to the community and manages the data nationwide, should be prepared. Also, in order to improve the accuracy of diagnosis and to obtain various types of information, a structured interview should be adopted as the psychological autopsy, as well as considering the use of social media. Investigation of specific risk factors for adolescent suicide through psychological autopsy can enable determination of the intervention point for effective suicide prevention.

• Anxiety and mood
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• v.5 no.2
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• pp.75-79
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• 2009

In this article, we review the efficacy of early interventions after traumatic incidents and during acute stress disorder (ASD). There are some evidences that psychopharmacological medications such as propronolol, morphine, and hydrocortisone are effective in the prevention of posttraumatic stress disorder (PTSD). Considering the role of selective serotonin reuptake inhibitors in hippocampal neurogenesis and an animal model of PTSD, early administration of selective serotonin reuptake inhibitors is also fairly promising. Other pharmacological treatments including benzodiazepines did not treat ASD nor prevent PTSD. There are good evidences that cognitive behavioral therapy including cognitive therapy and prolonged exposure is a valuable intervention for ASD and the most effective prevention for PTSD. No contolled researches on eye movement desensitization&reprocessing, psychodynamic psychotherapy and hypnotherapy have performed. Recent randomized controlled studies using psychological debriefing did not prove as a useful intervention for the prevention of PTSD until now, although the efficacy of debriefing has been at the centre of controversy.

• Journal of Home Health Care Nursing
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• v.25 no.2
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• pp.219-229
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• 2018

Purpose: This study explored the sexual harassment-related experience, awareness, coping, and institutional prevention schemes for health personnel in industrial settings. Methods: Data were collected using self - report questionnaires from 300 health personnels. Data were collected between September 1 and December 31, 2017. The collected data were analyzed using descriptive statistics. Results: Health personnels experienced 29% of sexual harassment, in order of verbal, visual, physical. The frequency of sexual harassment was higher when women were younger, particularly younger than men. Although the average health personnel's awareness of sexual harassment was high, the common coping style was passive such as distancing form the perpetrator. Institutional efforts to prevent sexual harassment included separating employees and staff, but perpetrators tended to account for a high proportion of the supervisors and staff. Conclusion: Health care managers should develop an effective and effective sexual harassment prevention education program by raising gender equality awareness in relation to the awareness of sexual harassment and identifying the influencing factors that can bring about appropriate sexual harassment coping behavior.

• KEPCO Journal on Electric Power and Energy
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• v.6 no.3
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• pp.289-296
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• 2020

In this paper, the effects of the spontaneous combustion inhibitor on the surface of the coal stockpile in the coal yard was investigated by numerical analysis. First, the numerical analysis method of the present study was compared with the results of the previous study by analyzing the case in which the spontaneous combustion inhibitor was not applied, while the effects of spraying the spontaneous combustion inhibitor for the prevention of spontaneous combustion onto various areas and positions was also analyzed. As a result, the larger the application area of the spontaneous combustion inhibitor, then the more effective it is for preventing spontaneous combustion as it blocks the oxygen inflow into the coal stockpile, while, when spraying the spontaneous combustion inhibitor from the bottom of the coal stockpile, then the greater the effect it has on the prevention of spontaneous combustion. In conclusion, it was most effective to spray the spontaneous combustion inhibitor from the bottom of the coal stockpile up to about 30% of the height of the coal stockpile, when considering the economic aspect.

• Child Health Nursing Research
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• v.25 no.2
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• pp.112-122
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• 2019

Purpose: The purpose of this study was to investigate the prevalence of diaper dermatitis (DD), knowledge of DD prevention and treatment, and diaper hygiene practices among mothers with diaper-wearing children. Methods: The participants were 176 mothers who presented to an outpatient clinic at a children's hospital with diaper-wearing children. Data were collected using a structured self-administered questionnaire. Results: The percent of correct answer for knowledge about DD was 59.7%. Almost half of the participants' children had experienced at least 1 episode of DD during the last 6 months. Inappropriate diaper hygiene practices, such as using talcum powder on DD and rubbing with a dry towel after cleansing, were reported. Moreover, only 37% of mothers used the recommended skin barrier to prevent DD. Although many children suffer from DD, levels of educational experience and perceived need for education on this topic were low. Almost 70% of mothers obtained DD-related information through internet sites. Conclusion: Educating parents about the etiology of DD and evidence-based diaper hygiene practices is an important aspect of effective DD prevention and treatment. Internet sites or smartphone apps may be effective methods for education on DD prevention and treatment considering parents' preferences for ways to obtain health information.

• Korean Journal of Health Education and Promotion
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• v.25 no.3
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• pp.77-94
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• 2008

Objectives: The purpose of this study was to develop the children obesity prevention program and to analyze how this program has an effect on students' degree of knowledge, attitude for obesity prevention. Methods: The study design was Compromise Experience Group Pre-Post Design. 238 students in the 4th and 5th grade of 4 elementary schools in Seoul were nonrandomly assigned to the study group(n=115) or the control group(n=113). The Program was applied for 3 times and surveys were conducted 2 times as pre-test and post-test. Results: 1. The obesity prevention CD-ROM was developed by analyzing of learners and educational facilities, selecting the study object and contents and producing educational methods and materials. The study contents were included definition, types, factors and side-effects of obesity, and It was contained dietary habit, exercise and life style for obesity prevention and healthy life. 2. Demographic characteristics were not significantly different between study group and control group. Among the subjects investigated, 27.8% of the study group and 38.1% of the control group stated that they had experienced in the obesity prevention program in past. 3. The obesity knowledge and attitude score after this obesity prevention program were improved significantly than before the program(P<0.001). Conclusion: The CD-ROM developed in this study for the children obesity prevention program was proven to be effective in improving obesity knowledge, attitude for the obesity prevention.

• Journal of Fashion Business
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• v.14 no.4
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• pp.1-9
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• 2010

The study verified the regulatory fit effect of the message focus and propensity regulatory focus delivered in the sales promotion situation of beauty services and products on the basis of the self-regulatory focus theory being actively discussed in the consumer behavior area of marketing. As the result of ANOVA analysis on the experimental design 2 (chronic regulatory focus: promotion focus/prevention focus, between factor) ${\times}$ 2 (message regulatory focus: promotion focus/prevention focus, within factor), the promotion focus group showed more positive response to the promotion focus message(4.88) of beauty services than the prevention focus group(4.40) so that the effect of regulatory fit appeared(t=1.79, p<.1), but the regulatory fit effect didn't appear in the prevention focus message(t=.58, p>.1) so that the hypothesis was partially supported. However, as for the promotion focus message of beauty products, the promotion focus group(4.62) showed more positive response than the prevention focus group(4.16), and as for the prevention focus message, the prevention focus group(4.89) showed more positive results than the promotion focus group(4.33) so that the effect of regulatory fit appeared(t=2.07, p<.05). Therefore, the result of the study shows that as for the service consumers perceive high risk, the sales promotion activity of the prevention focus message can be effective for prevention focus consumers and for promotion focus consumers as well. Otherwise, it suggests the marketing approach that the consumer evaluation is more positive when the advertising message focus fit the consumer regulatory focus.

• Research in Community and Public Health Nursing
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• v.24 no.4
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• pp.398-406
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• 2013

Purpose: The study was conducted to clarify effects of a clonorchiasis prevention education program for clonorchiasis prevention lecturers. Methods: The research adopted a single group pretest-posttest design to see effects of the educational program to prevent Clonorchis sinensis infection. The subjects of this study were 74 clonorchiasis prevention lecturers from primary health care facilities. The pretest was conducted before the clonorchiasis prevention education program and the post test was done after the 2-day program in August, 2011. Descriptive statistics, t-test, and ANOVA were conducted to analyze the data. Results: The confidence level in Clonorchiasis management activities was improved significantly from $4.1{\pm}0.53$ points before the education to $4.4{\pm}0.46$ points after the education (t=-5.117, p<.001). The knowledge level about prevention of Clonorchis sinensis was improved significantly from $16.1{\pm}2.72$ points before the education to $18.3{\pm}1.14$ points after the education (t=-6.629, p<.001). Conclusion: The results suggest that the education program was effective in improving the confidence and knowledge levels in Clonorchiasis management activities for the clonorchiasis prevention lecturers. Based on the results of this study, continuous research on how the increased knowledge and confidence levels of Clonorchis sinensis prevention affect the prevalence of Clonorchis sinensis infection.