• 대한한의학원전학회지
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• 제26권1호
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• pp.99-129
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• 2013

Objective : Most disease of the aged comprise chronic illness, hence the diet is important. Yet, the study on diet methodology for the remedy of the aged folks' aliments is scarce. The diet for the aged must be easy to digest- in regard to the physiological features of the aged, delightfully chewable, while meeting the expectation and guaranteeing nutrition-supply and remedial efficacy. Material and Method : This study is designed to accomplish following things with the Yang-lo-bong-chin-seo, a text on maintaining and upbringing the health for the aged: (1) classify the food recorded in the text in terms of cooking methods, (2) then sort the main ingredients in remedial herbal rice porridge(Yak-sun-jook) in food material science manner, (3) evaluate the cooking methods of the porridge for each and various symptoms, and (4) assess the features of each ingredient of the porridge, the value of it both in oriental medicine's and nutrition's scope. Results : 1) Among 64 main dishes recorded in Yang-lo-bong-chin-seo, rice porridge composes the majority, which is 64%. Stew and soup account for 60% of side dishes. 2) In 15 food cures, 43 remedial herbal rice porridges(Yak-sun-jook) were recorded. 3) Yak-sun-jook utilizes most chinese herbs as its food material. 4) Yak-sun-jook is made more with vegetable ingredients than animal ingredients and consist highly of chinese herbs. 5) Main ingredients in the porridges are effective in disease cure in addition to sufficient, well-balanced nutrition. 6) Cooking method of the porridge is grinding chinese herbs into powder or boiling them for a long time. Conclusion: All forementioned steps build the informational foundation - for this purpose the information be utilized - for making possible the development and the devising of pragmatic and feasible Remedial herbal rice porridge(Yak-sun-jook).

• 대한화장품학회지
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• 제29권2호
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• pp.37-65
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• 2003

새로운 주름개선 효능물질을 개발하기 위하여 여러 가지 세포배양 모델을 이용한 in vitro 효능물질의 검색방법을 이용하여 후보물질을 도출하고 있다. 이처럼 In vitro에서 선별된 주름개선 후보물질은 사람피부에 직접 도포 하였을 때 in vitro에서 와 는 달리 주름개선 효능이 없는 경우가 많이 있다. 즉 in vitro 검색결과와 사람피부에서의 효능은 현실적으로 큰 차이를 보인다는 것이다. 그러나 모든 효능 후보물질을 사람 피부에 직접 검사할 수는 없는 현실적 어려움이 있다. 이러한 애로점을 해결하기 위하여, 동물모델이나, 인공피부배양모델 등을 이용하는 추세이다. 이번 강의에서, 본인은 동물모델과 in vitro에서 효능 측정방법을 상세하게 리뷰 하고 각 방법에 대해 토의할 것이며, 임상 전 시험 결과를 보고 할 것이다. 그 중 특히 동물 모델은 주름개선 효능물질의 효능을 평가하는데 좋은 대상이 될 것이다.

• 대한지역사회영양학회지
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• 제15권4호
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• pp.507-512
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• 2010

This study was conducted to offer basic data that give effective ways to inform the country-of-origin labeling, where the ingredients they are serving are from, at school foodservice and to reconsider the importance of the labeling origin based on the survey by the elementary school students. 96.0% of the elementary school students agreed to the regulation about the country-of-origin labeling and the older students were influenced more by media and also supported the labeling. About the tendency of ingesting food from the country the students didn't like, 69% of them disagreed to eat. In the ways to label the country-of-origin labeling at school foodservice, elementary school students recognized easily the indication of origin designed by menu items, letter type. 76% of elementary school students checked the country-of-origin labeling posted at restaurants. When the students eat out, 68% of them were unwilling to have the food using the ingredients from the country they don't like. The country-of-origin for main ingredients such as beef, pork, chicken and other meat products, rice, kimchi had high importance scores. We found that the students think about the country-of-origin for main ingredients is important. Consequently, education and public relations of the country-of-origin labeling for elementary school students would be required.

• 대한암한의학회지
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• 제11권1호
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• pp.75-93
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• 2006

Jiaweicitaowan (JWCTW) has been used to inhibit recurrence and metastasis of cancer in clinical practice. Further study has shown its anti-metastatic and anti-angiogenic effects. By applying in vitro and in vivo anti-angiogenic evaluation model, the author assayed the each ingredients of JWCTW. The author performed the following experiments and the results are listed as below: Cell viability assay showed that the viability was almost identical between that of the control and that of the ingredients extract 40 ${\mu}g/m{\ell}$ treated, except of hexane fraction of Curcumae Radix (40 ${\mu}g/m{\ell}$, 2.0% of control), ethylacetate fraction (40 ${\mu}g/m{\ell}$, 26.7%), butanol fraction (20 ${\mu}g/m{\ell}$, 87.2%; 40 ${\mu}g/m{\ell}$, 12.5%) of Cremastrae appendiculatae Tuber, water fraction of Persicae Semen (40 ${\mu}g/m{\ell}$, 82.7%), ethylacetate fraction of Hippocampus (40 ${\mu}g/m{\ell}$, 85.3%). The results of gelatin zymogram assay showed that the ingredients of JWCTW decreases the gelatinolytic activity of MMP-9 from ECV304, at the concentration of 10 ${\mu}g/m{\ell}$. In in vitro invasion assay, the ingredients of JWCTW effectively inhibited the invasion of cancer cells as compared with the control (+PMA) groups. In capillary-like tube formation assay, the hexane and ethylacetate fractions of Curcumae Radix, Cremastrae appendiculatae Tuber and Persicae Semen showed the dramatic inhibition effects on tube formation of ECV304 at the concentration of 40 ${\mu}g/m{\ell}$. In ex vivo rat aortic ring assay, the hexane and ethylacetate fractions of Curcumae Radix, Cremastrae appendiculatae Tuber and Persicae Semen showed the inhibition effects on angiogenesis of rat aorta at the concentration of 40 ${\mu}g/m{\ell}$. According to the above research, the anti-angiogenic effects of the ingredients of JWCTW was proved and it suggested that the more effective prescription for anti angiogenesis could be developed.

• 대한한방종양학회지
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• 제7권1호
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• pp.39-60
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• 2001

Fuzhengfangaitang is a prescript for inhibiting recurrence and metastasis of cancer. We had examined the anti-metatstastic effect of Fuzhengfangaitang. Furthermore, we performed the following experiments with ingredients of Fuzhengfangaitang. The purpose of this thesis is to study what ingredients of Fuzhengfangaitang have more valuable anti-cancer effects. And the results are listed below: 1. Cell Viability assay At the dose of 400$\mu$g/ml, most ingredients of Fuzhengfangaitang depressed viability of ECV-304. And especially, Scutellaria barbata D. DON$50{\mu}g/ml$ : 53.118%, $100{\mu}g/ml$: 49.092%, $200{\mu}g/ml$ : 43.765%, $400{\mu}g/ml$ : 12.747%), Polygonum bistorta L.($50{\mu}g/ml$ : 45.554%, $100{\mu}g/ml$ : 45.554%, $200{\mu}g/ml$ : 0.0%, $400{\mu}g/ml$ : 0.0%) and Psoralea corylifolia L.($50{\mu}g/ml$ : 86.591%, $100{\mu}g/ml$ : 81.307%, $200{\mu}g/ml$ : 24.801%, $400{\mu}g/ml$ : 3.111%) highly depressed cell viability more than the other ingredients. (${\alpha}$<0.05) 2. Cell Proliferation assay Proliferation assay with ingredients of Fuzhengfangaitang on ECV-304 showed that Crataegus pinnatifuda BGE ($50{\mu}g/ml$: 63.276%, $100{\mu}g/ml$ : 64.092%, $200{\mu}g/ml$ : 68.966% $400{\mu}g/ml$ : 38.517%, ED50=$296.974{\mu}g/ml$), Polygonum bistorta L.($50{\mu}g/ml$ : 83.981%, $100{\mu}g/ml$ : 86.997%, $200{\mu}g/ml$ : 58.780%, $400{\mu}g/ml$ : 26.408%), ED50=$266.725{\mu}g/ml$) and Psoralea corylifolia L.($50{\mu}g/ml$ : 103.037%, $100{\mu}g/ml$ : 82.529%, $200{\mu}g/ml$ : 2.829%, $400{\mu}g/ml$ : 0.998%), ED50=$177.369{\mu}g/ml$) depressed cell proliferation more than the other ingredients. 3. Tube Formation assay Compared with the control group, most ingredients of Fuzhengfangaitang did not remarkably inhibited the Tube Formation assay of ECV-304 at the dose of $100{\mu}g/ml$. But, Polygonum bistorta L. highly inhibited the tube formation of ECV -304 at the lower dose of $50{\mu}g/ml$. 4. Rat Aortic Ring assay In comparison with the control group, Scutellaria barbata D. DON., root of Polygonum bistorta L. and Psoralea corylifolia L. restricted the angiogenesis of the rat aortic ring at the dose of $100{\mu}g/ml$. And the other ingredients of Fuzhengfangaitang did not restricted the angiogenesis of the rat aortic ring at that dose. Especially, Polygonum bistorta L. highly inhibited the angiogenesis of the rat aortic ring at the lower dose of $50{\mu}g/ml$. From our research, the anti-angiogenic effects of the ingredients of Fuzhengfangaitang was proven. Moreover, it will be helpful for designing more effective prescription for anti angiogenesis.

• 생약학회지
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• 제31권3호
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• pp.364-372
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• 2000

The Youngkaechulgamtang(Y) is composed of four herbal drugs, including Hoelen(H), Cinnamomi Ramulus(C), Atractylodis Rhizoma Alba(A) and Glycyrrhizae Radix(G). In oriental medicine literatures, Youngkaechulgamtang is described to be effective in headache, inflammation, uremia, gastritis, diarrhea, hypertension. To estimate the clinical effectiveness of Youngkaechulgamtang, several pharmacological experiments were carried out. The results are summarized as follows: On $HgCl_2-induced$ renal failure rat, Youngkaechulgamtang showed the significant increase of $Na^+,\;K^+,\;Cl^-$ contents in urine and the significant decrease of creatinine and BUN concentrations in serum. Youngkaechulgamtang was more effective than mixture of 4 ingredients in the urine volume and excretion of electrolytes. In the diuretic effect, Hoelen and Atractylodis Rhizoma Alba were more effective than other drugs.

• 한국식품영양과학회지
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• 제29권6호
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• pp.1003-1008
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• 2000

갓김치 제조시 필수적으로 첨가되는 주요 부재료별 갓김치의 항산화성 증진 효과와 이미 항산화성이 높다고 알려진 여러 가지 항산화성 특수 부재료의 첨가수준을 달리 하여 제조한 갓김치의 항산화성 증진 효과를 살펴보았다. 항산화 활성이 높은 특수 부재료를 선정하고 이들의 첨가를 달리하여 만든 갓김치의 항산화 특성을 살펴 본 결과는 다음과 같다. 1. 갓김치의 주요 부재료인 파, 마늘, 고춧가루, 생강 등이 갓김치의 항산화성 증진 효과에 미치는 영향을 살펴본 결과 고춧가루 첨가군＞생강 첨가군>마늘 첨가군>파 첨가군의 순이었으며, 적갓 김치군에서의 항산화성이 돌산갓 김치군에서 더 높았다 2. 더덕, 부추, 우엉, 다시마, 미 역, 청각 등을 첨가한 돌산갓 김치와 적갓 김치는 첨가하지 않은 갓김치에 비하여 항산화성 증진 효과를 나타내었으며, 특히 더덕, 우엉, 청각을 첨가한 갓김치군의 항산화성 증진 효과가 비교적 높게 나타났다. 또한 첨가되는 특수 부재료의 양에 비례하여 항산화 활성이 증가하는 것으로 나타났으며 항산화성이 우수한 재료들을 조합하여 첨가한 군에서의 항산화성 증진 효과가 각각 첨가한 군보다 증가하는 것을 관찰할 수 있었다. 3. 돌산갓김치의 용매추출물의 항산화성을 살펴보았을 때 일반 갓김치보다는 더덕 또는 청각을 첨가한 김치군이, 더덕 또는 청각 첨가갓김치 보다는 더덕과 청각을 함께 첨가한 갓김치군이 보다 우수한 것으로 나타나 일관된 경향성을 보였다.

• 한국식품과학회지
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• 제29권6호
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• pp.1228-1235
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• 1997

문헌을 이용한 표준화 배추 김치의 배합비를 표준 값으로 하고 표준편차 만큼의 양을 가감하여 관능검사 및 이화학적 실험과 기능성 실험으로 항돌연변이성과 항암성을 평가하여 배추김치의 재료배합비를 표준화하였다. 절인 배추 100에 대해 무 13.0, 파 2.0, 설탕 1.0, 고춧가루 3.5, 마늘 1.4, 생강 0.6, 멸치액젓 2.2, 염도 2.5% 또는 2.7%로 조절한 배추김치의 경우가 관능검사에서 주관적인 평가항목인 종합적인 냄새, 향미, 질감과 종합적인 평가에 있어서 좋았고, 객관적 평가항목인 군덕내, 군덕맛이 적게 감지되었으며, 이화학적 실험결과 및 재료배합비에 따른 $AFB_1$의 항돌연변이성과 암세포 성장 억제효과를 검토한 결과 모든 김치 시료에서 높은 항돌연변이효과와 암세포 성장 억제효과를 보였고, 특히 표준화 배추김치의 즙액은 84%의 항돌연변이 효과와 80%이상의 암세포 성장 억제 효과를 보여 관능성과 기능성의 연을 고려해 볼때 가장 적절한 배추김치의 표준화를 위한 재료배합비는 절인 배추 100g에 대해 무 13.0 g, 파 2.0 g, 설탕 1.0 g, 고춧가루 3.5 g, 마늘 1.4 g, 생강 0.6 g, 멸치 액젓 2.2 g, 염도 2.5 %인 것으로 나타났으며, 이는 문헌을 통한 표준화의 재료배합비 중 최종염도만 2.7에서 2.5로 변한 것 외에는 일치하였다.

• 가정과삶의질연구
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• 제18권1호
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• pp.17-30
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• 2000

using family ecosystem approach strong family perspective developmental perspective and current researches related to family studies and human development this study proposes a curriculum guideline of family life education for couples Curriculums for couples can be divided into the following broad categories: Understanding of couple's relationship ingredients of successful couple relations developmental aspects of couple relations crisis of relationship couple relationship in diverse family forms. Suggestions for the effective program management are added.

• 한국수산과학회지
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• 제34권4호
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• pp.309-314
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• 2001

소형 적색육어의 소비기호에 부정적으로 작용하고 있는 잔뼈를 연화시켜 제거하고 비린내를 저감시키기 위하여 대표적인 소형 적색육어인 꽁치, Cololabis saira를 김치양념과 유기산 그리고 미강을 첨가하여 $5\pm0.5^{\circ}C$에서 60일 동안 숙성시키면서 15일 간격으로 숙성 중 화학적 변화를 검토하였다. 마른간이 물간에 비해 염침투도 및 탈수도가 높아 조미양념과의 평형이 15일 정도 빨랐으며, 그로 인해 숙성 중 pH가 높고, 휘발성염기질소함량과 TBA가가 낮아 조미숙성제품 제조시 염 첨가방법은 마른간이 적합하였다. 마른간에 미강을 첨가한 제품은 첨가하지 않은 제품에 비해 미강에 함유되어 있는 아미노산이 제품으로 이행되어 정미성분의 함량을 나타내는 아미노태질소가 높았고, 단백질 산패억제 및 미강의 carotenoid와 tocopherol 둥의 항산화물질에 의한 지질산화 억제효과도 있어 저이용 자원의 활용 증대측면에서 상업적 제품화가 기대된다.