• Title/Summary/Keyword: effective diffusion

Search Result 844, Processing Time 0.026 seconds

Phytochemical Screening and Antibacterial Activity Coix lacryma-jobi Oil

  • Diningrat, Diky Setya;Risfandi, Marsal;Harahap, Novita Sari;Sari, Ayu Nirmala;Kusdianti, Kusdianti;Siregar, Henny Kharina
    • Journal of Plant Biotechnology
    • /
    • v.47 no.1
    • /
    • pp.100-106
    • /
    • 2020
  • Coix lacryma-jobi (Hanjeli) is known to posses anti-microbial properties. Therefore, phytochemical compounds of C. lacryma-jobi have been studied to produce novel antimicrobial agents as treatments against antibiotic-resistant bacteria.The objective of this study was to determine the phytochemical composition and antibacterial activity of the C. lacryma-jobi oil against Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. The phytochemical composition of the oil was determined via gas chromatography mass spectrophotometry (GC-MS). Moreover, agar disk and agar well diffusion were employed to screen the antibacterial activity of the oil. An agar well diffusion test was implemented to determinate MIC's (minimum inhibitory concentrations). Dodecanoic acid, tetradecanoic acid, 2,3-dihydroxypropylester, 1,3-dioctanoin, N-methoxy-N-methyl-3,4-dihydro-2H-thiopyran6-carboxamide, propanamide, 5-Amino-1-(quinolin-8-yl)-1,2,3-triazole-4-carboxamide, and pyridine were identified in the C. lacryma-jobi oil. The MIC value of the oil was 0.031 g/L and the MBC of the oil was 0.125 g/L effective in all test bacteria. Dodecanoic acid displayed inhibitory activity against gram-positive and gram-negative bacteria. Therefore, our research demonstrated C. lacryma-jobi (Hanjeli) oil exhibited antibacterial activity against E. coli, S. aureus, and B. subtilis. These research suggest that C. lacryma-jobi root oil could be used for medicinal purposes; however clinical and in vivo tests must be performed to evaluate its potential as an antibacterial agent.

Diffusion-hydraulic properties of grouting geological rough fractures with power-law slurry

  • Mu, Wenqiang;Li, Lianchong;Liu, Xige;Zhang, Liaoyuan;Zhang, Zilin;Huang, Bo;Chen, Yong
    • Geomechanics and Engineering
    • /
    • v.21 no.4
    • /
    • pp.357-369
    • /
    • 2020
  • Different from the conventional planar fracture and simplified Newton model, for power-law slurries with a lower water-cement ratio commonly used in grouting engineering, flow model in geological rough fractures is built based on ten standard profiles from Barton (1977) in this study. The numerical algorithm is validated by experimental results. The flow mechanism, grout superiority, and water plugging of pseudo plastic slurry are revealed. The representations of hydraulic grouting properties for JRCs are obtained. The results show that effective plugging is based on the mechanical mechanisms of the fluctuant structural surface and higher viscosity at the middle of the fissure. The formulas of grouting parameters are always variable with the roughness and shear movement, which play a key role in grouting. The roughness can only be neglected after reaching a threshold. Grouting pressure increases with increasing roughness and has variable responses for different apertures within standard profiles. The whole process can be divided into three stationary zones and three transition zones, and there is a mutation region (10 < JRCs < 14) in smaller geological fractures. The fitting equations of different JRCs are obtained of power-law models satisfying the condition of -2 < coefficient < 0. The effects of small apertures and moderate to larger roughness (JRCs > 10.8) on the permeability of surfaces cannot be underestimated. The determination of grouting parameters depends on the slurry groutability in terms of its weakest link with discontinuous streamlines. For grouting water plugging, the water-cement ratio, grouting pressure and grouting additives should be determined by combining the flow conditions and the apparent widths of the main fracture and rough surface. This study provides a calculation method of grouting parameters for variable cement-based slurries. And the findings can help for better understanding of fluid flow and diffusion in geological fractures.

Tc-99m hydroxymethylene diphosphonate scintigraphy, computed tomography, and magnetic resonance imaging of osteonecrosis in the mandible: Osteoradionecrosis versus medication-related osteonecrosis of the jaw

  • Ogura, Ichiro;Sasaki, Yoshihiko;Sue, Mikiko;Oda, Takaaki;Kameta, Ayako;Hayama, Kazuhide
    • Imaging Science in Dentistry
    • /
    • v.49 no.1
    • /
    • pp.53-58
    • /
    • 2019
  • Purpose: To present characteristic findings of Tc-99m hydroxymethylene diphosphonate (HMDP) scintigraphy, computed tomography (CT), and magnetic resonance (MR) imaging for osteonecrosis in the mandible, especially osteoradionecrosis(ORN) and medication-related osteonecrosis of the jaw(MRONJ). Materials and Methods: Thirteen patients with MRONJ and 7 patients with ORN in the mandible underwent Tc-99m HMDP scintigraphy, CT, and MR imaging (T1-weighted images[T1WI], T2-weighted images[T2WI], short inversion time inversion recovery images[STIR]), diffusion-weighted images[DWI], and apparent diffusion coefficient [ADC] mapping). The associations of scintigraphy, CT, and MR imaging findings with MRONJ and ORN were analyzed using the chi-square test with the Pearson exact test. Results: Thirteen patients with MRONJ and 7 patients with ORN in the mandible showed low signal intensity on T1WI and ADC mapping, high signal intensity on STIR and DWI, and increased uptake on scintigraphy. Periosteal bone proliferation on CT was observed in 69.2% of patients with MRONJ(9 of 13) versus 14.3% of patients with ORN(1 of 7)(P=0.019). Conclusion: This study presented characteristic imaging findings of MRONJ and ORN on scintigraphy, CT, and MR imaging. Our results suggest that CT can be effective for detecting MRONJ and ORN.

In vitro Study and Clinical Trial of Natural Essential Oils and Extract Against Malassezia Species

  • Lee, Min Young;Na, Eui Young;Yun, Sook Jung;Lee, Seung-Chul;Won, Young Ho;Lee, Jee-Bum
    • Journal of Mycology and Infection
    • /
    • v.23 no.4
    • /
    • pp.91-98
    • /
    • 2018
  • Background: Malassezia, a lipophilic yeast, is a causative agent for dandruff and seborrheic dermatitis. Many biological agents have been studied for anti-Malassezia effect but further studies are needed for their clinical application. Objective: The study was conducted to evaluate the inhibitory effect of different natural essential oils and a fruit extract on Malassezia species in an in vitro study and a clinical trial. Methods: The antifungal effects of natural essential oils and a fruit extract on Malassezia species (M. furfur and M. sympodialis) were evaluated by measuring the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) and using the disc diffusion method. Natural essential oils of citron seed, lavender, and rosemary and citrus junos fruit extract were used for the in vitro study. The clinical trial was conducted with a shampoo containing four ingredients. A total of 22 subjects used the shampoo every day for 4 weeks and were evaluated using clinical photography, trichoscopy, and sebumeter at baseline, 2 weeks, and 4 weeks after treatment. Results: Antifungal activity of agents was relatively lower in lavender and rosemary essential oils at MIC and MFC. Disc diffusion method revealed same results. In the clinical trial, the amount of sebum decreased statistically significantly and erythema, dandruff, and lesion extent also improved. Conclusion: The natural essential oils and fruit extract are effective for suppressing Malassezia activity, therefore these might be used as an alternative for treatment of dandruff and seborrheic dermatitis.

Effect of Porous Flow Field on PEMFC Performance with Dead Ended Anode System (Dead ended anode 시스템에서 다공성 유로가 연료전지 성능에 미치는 영향)

  • Kim, Junseob;Kim, Junbom
    • Applied Chemistry for Engineering
    • /
    • v.33 no.6
    • /
    • pp.646-652
    • /
    • 2022
  • The dead-end anode (DEA) system is a method that closes the anode outlet and supplies fuel by pressure. The DEA method could improve fuel usage and power efficiency through system simplification. However, flooding occurs due to water and nitrogen back diffusion from the cathode to the anode during the DEA operation. Flooding is a cause of decreased fuel cell performance and electrode degradation. Therefore, tthe structure and components of polymer electrolyte membrane fuel cell (PEMFC) should be optimized to prevent anode flooding during DEA operation. In this study, the effect of a porous flow field with metal foam on fuel cell performance and fuel efficiency improvement was investigated in the DEA system. As a result, fuel cell performance and purge interval were improved by effective water management with a porous flow field at the cathode, and it was confirmed that cathode flow field structure affects water back-diffusion. On the other hand, the effect of the porous flow field at the anode on fuel cell performance was insignificant. Purge interval was affected by metal foam properties and shown stable performance with large cell size metal foam in the DEA system.

Effects of hairline treatment on surface blackening and thermal diffusion of Zn-Al-Mg alloy-coated steel sheet (Zn-Al-Mg 합금도금강판의 헤어라인 처리가 표면흑색화 및 열확산도에 미치는 영향)

  • Jin Sung Park;Duck Bin Yun;Sang Heon Kim;Tae Yeob Kim;Sung Jin Kim
    • Journal of the Korean institute of surface engineering
    • /
    • v.56 no.1
    • /
    • pp.69-76
    • /
    • 2023
  • The effects of hairline treatment on surface blackening and thermal diffusion behaviors of Zn-Al-Mg alloy coated steel sheet were evaluated by the three-dimensional surface profiler and laser-flash technique. The metallographic observation of coating damages by hairline treatments showed that several cracks were initiated and propagated along the interface between primary Zn/eutectic phases. As the hairline processing became more severe, the crack occurrence frequency in eutectic phase of coating layer and the surface roughness increased, which had a proportional relationship with the level of blackening on the coating surface. In addition, the higher interfacial areas of the blackened coating surface, caused by the hairline process, led to an increase in thermal diffusivity and conductivity of the coated steel sheet. On the other hand, when the coating damage by hairline treatment was excessive and the steel substrate was exposed, there was little difference between the thermal diffusivity/conductivity of the untreated sample though the blackening degree was higher than that of untreated sample. This work suggests that the increase in the surface areas of the coating layer without exposure to steel substrate through hairline treatment can be one of the effective technical strategies for the development of Zn-Al-Mg alloy coated steel sheets with higher blackening level and thermal diffusivity.

Vitalization study on floricultural industry by analyzing Domestic flower consumption realities (국내 꽃 소비실태 분석을 통한 화훼산업 활성화 방안에 대한 연구)

  • Yang, J.H.;Park, N.B.
    • Journal of Practical Agriculture & Fisheries Research
    • /
    • v.17 no.1
    • /
    • pp.21-43
    • /
    • 2015
  • Korean floricultural industry has grown under the full backing of government, as it placed itself as the main export item since 2000s. Despite its high-speed growth after the domestic production scale of trillion won, the floricultural industry lost its pace after 2005, due to the market-opening of agricultural product and global economic depression. Although the national income is growing and the level of civilized living is following, spending on flowers is faltering. As of such circumstances, necessity for analyzing flower consumption trend and behavior has came out, along with the calls for expansion plan of flower consumption, under the basis of result analysis on consumer reports. The result of the research contains the trend/consumption behavior analysis on domestic and foreign flower industry to boost floricultural industry, along with reviews on various studies of the developmental process of domestic and foreign cut-flowers/pot-plants consumption trend. Also this study has reached to the various recognition of people toward flower, through a public survey. Through such results, this study would like to propose the measures for diffusion of flower-consumption culture, achieving the improvement of life-quality of public along. First, efforts on reviewing the customer accessibility is essential to create flower- culture and the consumption. Second, to eliminate the obstacles that prevents flowers from public's daily life is essential. Third is the effective public-relations on flowers. To create consuming culture and to adhere the positive images, it is essential to research and systematically organize categories of color, scent, and elements of flower and utilize them. Last proposal is the organization of flower-concerned personnels and the leading groups. The change is affected by the economical, social environment, along with the emotions of consumers. Therefore the necessity for the leading group to be the control-tower of such changes are very clear.

Analysis of Crime Prevention Effects of CCTV Installation (CCTV 설치로 인한 도시공간 범죄예방효과 분석)

  • Hye-Lim KIM;Sun-Young HEO;Tae-Heon MOON
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.26 no.4
    • /
    • pp.188-199
    • /
    • 2023
  • CCTV is widely used as a crime prevention method globally; however, there is insufficient evidence regarding its effectiveness. This study assesses the suitability of CCTV locations and their impact on crime prevention. First, to analyze the appropriateness of the location of CCTVs, we overlaid the locations of crimes and CCTV, and found that there are many cases where CCTV were placed where crime rarely occurred. Using various cases, we verified CCTV's crime prevention effectiveness. The WDQ was applied to comprehensively analyze the impact of CCTV surveillance area and surrounding areas to determine the crime prevention effect. As a result of the analysis, CCTV was found to be effective in preventing crime. In 53.09% of the cases, there was a diffusion effect of crime control benefits in the surrounding area, which was four times more than the cases with a transfer effect. Thus, strategically installing CCTV in appropriate locations enhances crime prevention effectiveness based on spatial analysis.

Development of Numerical Technique to Analyze the Flow Characteristics of Porous Media Using Lattice Boltzmann Method (격자볼쯔만법을 이용한 다공체의 유동특성 분석방법 개발에 관한 연구)

  • Kim, Hyung Min
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.40 no.11
    • /
    • pp.689-695
    • /
    • 2016
  • The performance of proton exchange membrane fuel cells (PEMFC) is strongly related to the water flow and accumulation in the gas diffusion layer (GDL) and catalyst layer. Understanding the behavior of fluid from the characteristics of the media is crucial for the improvement of the performance and design of the GDL. In this paper, a numerical method is proposed to calculate the design parameters of the GDL, i.e., permeability, tortuosity, and effective diffusivity. The fluid flow in a channel filled with randomly packed hard spheres is simulated to validate the method. The flow simulation was performed by lattice Boltzmann method with bounce back condition for the solid volume fraction in the porous media, with different values of porosities. Permeability, which affects the flow, was calculated from the average pressure drop and the velocity in the porous media. Tortuosity, calculated by the ratio the average path length of the randomly injected massless particles to the thickness of the porous media, and the resultant effective diffusivity were in good agreement with the theoretical model. The suggested method can be used to calculate the parameters of real GDL accurately without any modification.

An Effective Multiplication Factor Calculation of Uniform Lattices of $UO_2-PuO_2$ Fueled System ($UO_2-PuO_2$ 노심에서의 유효증배계수계산)

  • Sang Keun Lee;Ji Bok Lee;Chang Saeng Rim;Chang Kun Lee;Chang Hyun Chung
    • Nuclear Engineering and Technology
    • /
    • v.14 no.3
    • /
    • pp.138-147
    • /
    • 1982
  • A theoretical basis for analysis of plutonium-hearing fuel in a thermal nuclear power reactor has been established. The analysis of UO$_2$-PuO$_2$ fueled, light water moderated uniform lattice experiments has been performed. A unit cell program, KARATE, which is based on the theoretical models of GAM and THERMOS with some modifications, has been developed to generate a few-group cross-sections. These cross-sections are subsequently used in the diffusion theory code, KIDD, to compare the calculated values of the effective multiplication factor with the measured. The average value of the effective multiplication factor for 41 selected critical experiments is estimated to be 0.9997 with standard deviation of 0.43%. This illustrates the fact that KARATE/KIDD system can be effectively used for the analysis of uniform lattices of UO$_2$-PuO$_2$fuels.

  • PDF