• Title/Summary/Keyword: effective component

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The Characteristic Analysis of Calcareous Deposit Films Formed on Steel Plate by Cathodic Current Process in Marine Environment (해양환경 중 음극전류 프로세스에 의해 강판에 형성된 석회질 피막의 특성 분석)

  • Park, Jun-Mu;Kang, Jae Wook;Choi, In-Hye;Lee, Seung-Hyo;Moon, Kyung-Man;Lee, Myeong-Hoon
    • Journal of the Korean institute of surface engineering
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    • v.49 no.2
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    • pp.166-171
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    • 2016
  • Cathodic protection is widely recognized as the most cost effective and technically appropriate corrosion prevention methodology for the port, offshore structures, ships. When applying the cathodic protection method to metal facilities in seawater, on the surface of the metal facilities a compound of calcium carbonate($CaCO_3$) or magnesium hydroxide($Mg(OH)_2$) films are formed by $Ca^{2+}$ and $Mg^{2+}$ ions among the many ionic components dissolving in the seawater. And calcareous deposit films such as $CaCO_3$ and $Mg(OH)_2$ etc. are formed by the surface of the steel product. These calcareous deposit film functions as a barrier against the corrosive environment, leading to a decrease in current demand. On the other hand, the general calcareous deposit film is a compound like ceramics. Therefore, there may be some problems such as weaker adhesive power and the longer time of film formation uniting with the base metal. In this study, we tried to determine and control the optimal condition through applying the principle of cathodic current process to form calcareous deposit film of uniform and compact on steel plate. The quantity of precipitates was analyzed, and both the morphology, component and crystal structure were analyzed as well through SEM, EDS and XRD. And based on the previous analysis, it was elucidated mechanism of calcareous deposit film formed in the sacrificial anode type (Al, Zn) and current density (1, 3, $5A/m^2$) conditions. In addition, the taping test was performed to evaluate the adhesion.

Prevention of Pressure Ulcer using the Pressure Ulcer Risk Assessment Based on Braden Scale (Braden Scale에 기초한 욕창발생 위험군 선별도구를 이용한 욕창의 예방)

  • Oh, Deuk Young;Kim, Jee Hoon;Lee, Paik Kwon;Ahn, Sang Tae;Rhie, Jong Won
    • Archives of Plastic Surgery
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    • v.34 no.4
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    • pp.466-470
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    • 2007
  • Purpose: Active prevention is an essential component in reducing the development of pressure sores. For the high-risk patient group, following the certified pressure sore screening scale as well as educating the patient and the nurses who care for them can lead to optimal management of these patients. Applying a risk assessment scale along with a prevention strategy can reduce medical costs and length of stays at the hospital. The purpose of this study is to evaluate the efficacy of a new pressure sore risk assessment scale based on the universally recommended Braden scale and our prevention program. Methods: From June to August, 2003, our pressure ulcer risk assessment scale was applied to a total of 1882 patients admitted to the experimental group (intensive care unit, neurosurgery, general surgery, and oncology units). It was based on Braden scale. We analysed sensitivity, specificity, positive and negative predictive value and ROC curve to evaluate its efficacy. Pressure ulcer prevention program was composed of patient's education using protocol and specific nursing care. The incidence of pressure ulcers was also measured during the 3 months period, and those were compared to the control group of 1789 patients from March to May, 2002. Results: 118(6.27%) of the experimental group were high-risk with an incidence of pressure ulcers measuring 4 (0.21%). Sensitivity, specificity, positive and negative predictive value of our scale were 100%, 94%, 4%, 100%, respectively, and AUC(area under the curve) was 0.992. In the control group, the incidence of pressure ulcers was 11(0.61%). Statistical analyses using chisquared tests with a significance level of 5%, the results were such that ${\chi }^2=3.6482$(p=0.0561). The results proved to be statistically significant in borderline. Conclusion: The results from this study proved that pressure sore risk assessment scale based on Braden scale has an excellent efficacy, and shows that our pressure ulcer prevention program is partially effective in reducing pressure ulcer incidence.

Effects of Drying Methods on Content of Active Components, Antioxidant Activity, and Color Values of Saururus chinensis Bail (건조방법에 따른 삼백초의 유효성분 함량, 항산화능 및 색도)

  • Kim, Min-Ja;Kim, In-Jae;Nam, Sang-Young;Lee, Cheol-Hee;Yun, Tae;Song, Beom-Heon
    • Korean Journal of Medicinal Crop Science
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    • v.14 no.1
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    • pp.8-13
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    • 2006
  • This study was carried out to investigate drying methods for keeping freshness and active components of aerial part of Saururus chinensis. Chopped samples were prepared using hot air drying, hot air drying + roasting, presteamed + hot air drying, freeze drying, and sun drying. Drying time was shorter $88{\sim}93%$ in hot air drying and freeze drying than in sun drying. Percentage of dry matter was higher in the order of freeze drying > sun drying > hot air drying, and moisture content in the order of sun drying > hot air drying > freeze drying. The contents of total phenolics and quercetin related substances were greater in the order of freeze drying > hot air drying > sun drying, while were decreased due to treatments before or after hot air drying. Electron donating ability (EDA) was highest in freeze drying, and showed a little difference between hot air drying and sun drying, but was increased because of treatments before or after hot air drying. In color values, the a value was lower in the order of freeze drying < hot air drying < sun drying. The contents of active components of plant parts of hot air dried were higher in the order of flower >leaf > chopped sample > stem. EDA showed similar tendency with those. The a value was lower in the order of leaf < chopped sample < flower < stem. As a result, freeze drying of chopped samples or hot air drying of leaf and flower were effective to maintain qualities of aerial part of Saururus chinensis.

Effect of M11C (Non-lectin Components) Obtained from Korean Mistletoe on the $IL-1\beta$ Secretion from Mouse Splenocytes (쥐의 비장세포로부터 $IL-1\beta$ 분비에 있어서 한국산 겨우살이 추출물 M11C (비렉틴 구성물질)의 효과)

  • Jun, Myung-Ha;Kang, Tae-Bong;Chang, Sung-Ho;Choi, Wahn-Soo;Seong, Nak-Sul;Her, Erk
    • Korean Journal of Medicinal Crop Science
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    • v.15 no.1
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    • pp.38-45
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    • 2007
  • Korean mistletoe (Viscum album L) extract has been found to posses immunoregulating activity. In this study, Korean mistletoe extract, M11C (non-lectin components), was used to know whether this extract activates splenocytes to secret interleukin $1\beta(IL-1\beta)$. The splenocytes were treated with M11C, and then collected the supernatant and cell lysate that were prepared to analyze the level of $IL-1\beta$, using ELISA, immunoblotting, and RT-PCR. Maximum effective dose and time of M11C on $IL-1\beta$ secretion from splenocytes were $200{\mu}g/m\ell$ and 8 hours, respectively. Treatment dose and time for the maximum expression of $IL-1\beta$ mRNA were $200{\mu}g/m\ell$ and 4 hours, respectively. Saccharide degradation enzyme Viscozyme L completely blocked the effect of M11C on $IL-1\beta$ secretion from splenocytes. As the result, among non-lectin components saccharide could be regarded as a main component for $IL-1\beta$ expression from splenocytes.

Effects of Organic Amendments on Soil Microbial Community in Red Pepper Field (시용 유기물의 종류가 고추 재배지 토양 미생물상에 미치는 영향)

  • Park, Kee-Choon;Kim, Yeong-Suk;Kwon, Oh-Hoon;Kwon, Tae-Ryong;Park, Sang-Gu
    • Korean Journal of Soil Science and Fertilizer
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    • v.41 no.2
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    • pp.118-125
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    • 2008
  • Diverse organic amendments available in local areas have been used to improve soil quality in red pepper field and so the need for investigating the soil chemical and biological properties changed by the organic amendments application is increasing. Soil microbial diversities were measured by phospholipid fatty acid (PLFA) and Biolog $EcoPlate^{TM}$. Compost was most effective for improving soil chemical properties including pH, EC, total nitrogen, P, K, and Ca, and bark increased soil organic matter significantly (P=0.05). Compost increased the fatty acids indicating actinomycetes and vascular arbuscular fungi, and ratio of cy19:0/18:1w7c and monounsaturated fatty acids/saturated fatty acids in soils in PLFA analysis. Bark increased soil fungal indicators in PLFA analysis (P=0.05). Principal component analysis of Biolog EcoPlate data and PLFA differentiated the compost- and bark-amended soils from other organic matteramended soils especially the soil incorporated with compost. More researches are needed to use bark for improving soil microbial properties because the soil chemical and microbiological properties caused by compost and bark are significantly different.

The Hypoglycemic Effect of Supungsunkihwan on Impaired Glucose Tolerance & Mild NIDDM Patiens (수풍순기환(搜風順氣丸)이 내당능장애 환자와 경증 당뇨병환자의 혈당조절에 미치는 영향)

  • Kwon, Young-Gu;Choi, Ki-Lim;Lee, Jin-Sin;Ahn, Young-Min;Ahn, Se-Young;Doo, Ho-Kyung;Lee, Byung-Cheol
    • The Journal of Internal Korean Medicine
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    • v.22 no.3
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    • pp.285-290
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    • 2001
  • Purpose : Impaired glucose tolerance (IGT) was standardized in 1979 by the National Diabetes Data Group and the World Health Organization as a risk factor for type 2 diabetes, replacing groups such as 'borderline' and 'chemical' diabetes. The main clinical significance of IGT is as a risk factor for type 2 diabetes and as a risk factor for cardiovascular disease and as a component of the metabolic syndrome. In 1997 the American Diabetes Association(ADA) was proposed the new classification and diagnostic criteria for diabetes, which is strict with the diagnostic baseline of Diabetes from 140mg/dl to 126mg/dl. And it's main purpose is to prevent chronic complications by early diagnosis and treatments. In the oriental medicine, Supungsunkihwan has been used in treatments of Diabetes including IGT & NIDDM, however there is not enough studies about the its objective hypoglycemic effect. so in order to investigate whether there is hypoglycemic effect of Supungsunkihwan, clinical studies were performed with IGT and mild NIDDM patients. Methods : Prior to the study, fasting blood sugar(FBS) and postprandial 2hrs(PP2hrs) glucose were checked. In addition, ECG, cholesterol, TG, HbA1c levels were measured, and the dinical characteristics of patients that can be influence to the blood sugar level such as age, gender, rest type, diet type were surveyed. Supungsukihwan was administered for 7 days, and FBS & PP2hrs were measured again after the therapy. Result : PP2hrs glucose levels were decreased by the administration of Supungsunkihwan. And It's hypoglycemic effects has the correlation with age. That is, the more age increase, the more hypoglycemic effect decrease. Conclusion : Supungsukihwan has hypoglycmic effects on IGT & mild NIDDM patients and it is more effective when administrated to young patients relatively.

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Integrated Schistosomiasis and Soil-Transmitted Helminthiasis Control over Five Years on Kome Island, Tanzania

  • Kaatano, Godfrey M.;Siza, Julius E.;Mwanga, Joseph R.;Min, Duk-Yong;Yong, Tai-Soon;Chai, Jong-Yil;Ko, Yunsuk;Chang, Su Young;Kullaya, Cyril M.;Rim, Han-Jong;Changalucha, John M.;Eom, Keeseon S.
    • Parasites, Hosts and Diseases
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    • v.53 no.5
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    • pp.535-543
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    • 2015
  • Integrated control strategies are important for sustainable control of schistosomiasis and soil-transmitted helminthiasis, despite their challenges for their effective implementation. With the support of Good Neighbors International in collaboration with National Institute of Medical Research, Mwanza, Tanzania, integrated control applying mass drug administration (MDA), health education using PHAST, and improved safe water supply has been implemented on Kome Island over 5 years for controlling schistosomiasis and soil-transmitted helminths (STHs). Baseline surveys for schistosomiasis and STHs was conducted before implementation of any integrated control strategies, followed by 4 cross-sectional follow-up surveys on randomly selected samples of schoolchildren and adults in 10 primary schools and 8 villages, respectively, on Kome islands. Those follow-up surveys were conducted for impact evaluation after introduction of control strategies interventions in the study area. Five rounds of MDA have been implemented from 2009 along with PHAST and improved water supply with pumped wells as other control strategies for complementing MDA. A remarkable steady decline of schistosomiasis and STHs was observed from 2009 to 2012 with significant trends in their prevalence decline, and thereafter infection rate has remained at a low sustainable control. By the third follow-up survey in 2012, Schistosoma mansoni infection prevalence was reduced by 90.5% and hookworm by 93.3% among schoolchildren while in adults the corresponding reduction was 83.2% and 56.9%, respectively. Integrated control strategies have successfully reduced S. mansoni and STH infection status to a lower level. This study further suggests that monitoring and evaluation is a crucial component of any large-scale STH and schistosomiasis intervention.

Induction of Apoptotic Cell Death by Cordycepin, an Active Component of the Fungus Cordyceps militaris, in AGS Human Gastric Cancer Cells (동충하초 유래 cordycepin에 의한 AGS 인체 위암세포의 apoptosis 유발)

  • Lee, Hye Hyeon;Jeong, Jin-Woo;Choi, Yung Hyun
    • Journal of Life Science
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    • v.26 no.7
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    • pp.847-854
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    • 2016
  • Cordycepin, a derivative of the nucleoside adenosine, is one of the active components extracted from fungi of genus Cordyceps, and has been shown to have many pharmacological activities. In this study, we investigated the effects of cordycepin on proliferation and apoptosis of human gastric cancer AGS cells, and its possible mechanism of action. Treatment of cordycepin resulted in significant decrease in cell viability of AGS cells in a concentration-dependent manner. A concentration-dependent apoptotic cell death was also measured by agarose gel electrophoresis and flow cytometery analysis. Molecular mechanistic studies of apoptosis unraveled cordycepin treatment resulted in an enhanced expression of tumor necrosis factor-related apoptosis-inducing ligand, death receptor 5 and Fas ligand. Furthermore, up-regulation of pro-apoptotic Bax, and down-regulation of anti-apoptotic Bcl-2 and Bcl-xL expression were also observed in cordycepin-treated AGS cells. These were followed by activation of caspases (caspase-9, -8 and -3), subsequently leading to poly (ADP-ribose) polymerase cleavage. Taken together, these findings indicate that cordycepin induces apoptosis in AGS cells through regulation of multiple apoptotic pathways, including death receptor and mitochondria. Although further mechanical studies are needed, our results revealed that cordycepin can be regarded as a new effective and chemopreventive compound for human gastric cancer treatment.

A Systemic Model for the Gifted Education (체제적인 영재교육을 위한 Renzulli의 전교 심화학습 모형(SEM)의 개성방안)

  • Park, Eun-Young
    • Journal of Gifted/Talented Education
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    • v.10 no.2
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    • pp.1-23
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    • 2000
  • The Schoolwide Enrichment Model(SEM) is a representative model for the gifted education. As the model seems to be more conceptual in nature, it is hard to respond to the different interests and changing needs of the gifted learners. Also it does not provide specific procedures and prescriptions in teaching-learning processes for the teachers. Therefore, SEM needs to be modified into a Systemic Model that is more flexible and procedural. The paper proposes an Instructional Systems Design(ISD) model for SEM. The Systemic Model for SEM consists of 5 major steps. These are as follows: Planning, Diagnosis, Prescription, Implementation, Evaluation. In Planning step, there is a six-stage procedure for initiating the implementation of the SEM. In Diagnosis step, there are two-phases in identifying students for participation in the SEM and assessing strengths, interests, and talents of the learners and recording in The Total Talent Portfolio(TTP). In Prescription step, Curriculum Compacting is administered as a systematic procedure for modifying thecurriculum for above-average ability students. In Implementation step, Enrichment Learning and Teaching is an instructional strategy designed to promote active engagement in learning for teachers and students. Whenever each step has completed, Evaluation step should be followed. These 5 steps are repetitive, cycling and interactive. That is, each one becomes input for the next step, process for itself, and output for the previous step. Each step is monitored through the process of Review and Revision step. In conclusion, the paper suggests six strengths of the Systemic Model for SEM; The Model (1) provides the specific procedure in teaching-learning process; 92) has interactive relations with each component; (3) can be revised continuously for creation of the most effective system; (4) can be implemented more flexibly; (5) can be developed as an unique system for each school; (6) facilitates communications between teachers and students.

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Natural Dyeing of Rayon Fabric using Loess (황토를 이용한 인견직물의 천연염색)

  • Jung, Yang-Sook;Bae, Do-Gyu
    • Current Research on Agriculture and Life Sciences
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    • v.31 no.3
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    • pp.193-199
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    • 2013
  • This study dyed rayon fabric using loess as a natural colorant. To obtain the optimal dyeing conditions, various dyeing conditions were examined (temperature, pH, time, and concentration). The color fastness was evaluated using standard washing and rubbing fastness tests. The results were as follows: The loess powder particle size ranged from 0.4 to $1.7{\mu}m$ with a distribution range of 1.1 to $1.4{\mu}m$, representing a fine and uniform manufactured loess powder. The loess component analysis showed a large amount of silicon dioxide and aluminum oxide. TheFT-IR spectra showed that the ammonium group in the rayon fabric produced N-H banding at $1,540cm^{-1}$. The highest K/S value for the rayon fabric was obtained when the pH was 8.0, and this value increased rapidly with a longer dyeing time and when increasing the loess concentration to 30% (w/v). Pre-treatment with a soybean solution produced the highest K/S value for the rayon fabric with a loess concentration of 30% (w/v). The SEM analysis showed a higher amount of loess adhered to the rayon fabric surface when increasing the loess concentration. However, pre-treatment with a cationic agent and soybean solution resulted in a much higher attachment of loess to the fabric surface. Thus, the experimental results showed that using a cationized fabric and pre-treatment with a soybean solution are more effective when dyeing rayon fabric with loess than when using only loess.

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