• The Korean Journal of Nuclear Medicine
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• v.34 no.5
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• pp.381-392
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• 2000

Purpose: We compared the reproducibility of $^{201}Tl\;and\;^{99m}Tc$-sestamibi (MIBI) gated SPECT measurement of myocardial function using the Germano algorithm Materials and Methods: Gated SPECT acquisition was repeated in the same position in 30 patients who received $^{201}Tl$ and in 26 who received $^{99m}Tc$-MIBI. The quantification of end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF) on $^{201}Tl\;and\;^{99m}Tc$-MIBI gated SPECT was processed independently using Cedars quantitative gated SPECT software. The reproducibility of the assessment of myocardial function on $^{201}Tl$ gated SPECT was compared with that of $^{99m}Tc$-MIBI gated SPECT Results: Correlation between the two measurements for volumes and EF was excellent by the repeated gated SPECT studies of $^{201}Tl$ (r=0.928 to 0.986; p<0.05) and $^{99m}Tc$-MIBI (r=0.979 to 0.997; p<0.05). However, Bland Altman analysis revealed the 95% limits of agreement (2 SD) for volumes and EF were tighter by repeated $^{99m}Tc$-MIBI gated SPECT (EDV: 14.1 ml, ESV: 9.4 ml and EF: 5.5%) than by repeated $^{201}Tl$ gated SPECT (EDV: 24.1 ml, ESV: 18.6 ml and EF: 10.3%). The root mean square (RMS) values of the coefficient of variation (CV) for volumes und EFs were smaller by repeated $^{99m}Tc$-MIBI gated SPECT (EDV: 2.1 ml, ESV 2.7 ml and EF: 2.3%) than by repeated $^{201}Tl$ gated SPECT (EDV: 3.2 ml, ESV: 3.5 ml and EF: 5.2%). Conclusion: $^{99m}Tc$-MIBI provides more reproducible volumes and EF than $^{201}Tl$ on repeated acquisition gated SPECT. $^{99m}Tc$-MIBI gated SPECT is the preferable method for the clinical monitoring of myocardial function.

• The Journal of Korean Academy of Prosthodontics
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• v.55 no.4
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• pp.394-402
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• 2017

Purpose: The purpose of this study is to evaluate the displacement of artificial tooth of monolithic complete denture manufactured by milling and 3D printing method in which the denture base and the artificial teeth are simultaneously made. Materials and methods: Twelve upper and lower complete dentures for each were made by milling and 3D printing method. Group Up and Group Lp are a group of upper and lower dentures made by printing, and Group Um and Group Lm are denture groups made by milling. Group Uc and Group Lc are is a group of finally designed upper and lower dentures respectively. Measurements were performed between both central incisors (AB, ab), both canines (CD, cd), both first molars (EF, ef), between an incisor and a first molar (AE, ae), and between incisor and lingual point (AG, ag) for each upper and lower denture. Results: AG and ag value between printed dentures and original ones as well as between milled dentures and original ones showed a statistically significant difference (One-way ANOVA, P<.05) in both lower and upper monolithic dentures. In the lower monolithic ones, ab, cd and ef value revealed a significant difference between Group Lp and Group Lm (One-way ANOVA, P<.05). Conclusion: Dentures made using milling or 3D printers revealed statistically significant difference compared with those of original data. However, it showed clinically very accurate reproducibility.

• Korean Journal of Environmental Biology
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• v.34 no.1
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• pp.48-55
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• 2016

This study investigates the effect of effluent organic matter (EfOM) from sewage wastewater treatment plants on estrogenic activity reduction of bisphenol A (BPA) by UV photolysis. The EfOM and Suwannee River natural organic matter (SR-NOM) as reference were isolated into hydrophobic (HPO), transphilic (TPI) and hydrophilic (HPI) fractions depending on polarity. The specific ultraviolet absorbance (SUVA) analysis indicated that EfOM showed similar properties to microbially derived organic matters with low hydrophobicity, which is different from SR-NOM having high hydrophobicity. UV irradiation upto 3 hr significantly reduced SUVA values of both EfOM and SR-NOM (p<0.0001), depending on the polarity of organic matters. In the absence of organic matters, the relative estrogenic activity (REA) of BPA ($5.0{\times}10^{-5}M$) was decreased from 86% to 63% by UV photolysis (2 hr). However, the decrease of mean REA was from 68% to 37% in the presence of organic matters, which was significantly independent on the type (EfOM or SR-NOM) and polarity (HPO, TPI or HPI) of organic matters (p>0.05). As a result, the reduced REA by UV photolysis of BPA with and without organic matters was 31% and 23%, respectively, suggesting that both EfOM and SR-NOM accelerated the photolytic reduction of BPA estrogenic activity.

• Journal of Environmental Impact Assessment
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• v.27 no.1
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• pp.56-72
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• 2018

North Korea has been in ecologically deficit state since 1966, despite of lack of energy and food resources. Trends of the Biocapacity (BC), the Ecological Footprint (EF), and the Ecological Deficit (ED) of North Korea were shown and five factors influencing on the Overshoot Rate (OSR) which is the ratio of the BC and the EF in North Korea was analyzed in this study. The five factors consist of two factors affecting to the EF and three factors affecting to the BC in North Korea. Two of the five factors are affecting to the EF those are population, the EF per capita (EFPC) which indicates the individual environmental consumption intensity, and three are affecting to the BC those are the land area, the yield factor, and the value multiplying the equivalence factor and the intertemporal yield factor. The EF has contributed more than the BC to the OSR. From 1966 to mid-1990s, the EFPC was the most contributing factor at about 60%, and after mid-1990s, population at about 40~60%. Contribution ratio of land area and the yield factor have increased after mid-1990s up to 15% and 18%, respectively. The BC of cropland which has decreased due to a decrease in productivity. In order to reduce the ED of North Korea, improvement of productivity of cropland and restoration of forest. Forest area has decreased significantly since 1990 in NK. And ways to solve the food shortage problem which influences on decrease of both productivity of cropland and forest area.

• Korean Journal of Poultry Science
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• v.48 no.1
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• pp.41-50
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• 2021

Although feather-sexing using sex-linked genes related to feather development is a widely used chick sexing method in the poultry industry, the feather-sexing method has yet to be used for Korean native chickens (KNCs). The purpose of this study was to construct a KNC feather-sexing line using early-feathering (EF) and late-feathering (LF) genes for industrial application. Using 557 reddish-brown KNCs as the basal flock, frequencies of the EF (k) and LF (K) genes were estimated to be 0.814 and 0.186, respectively. This indicating that it would be feasible to construct a feather-sexing line using this chicken group, and we accordingly constructed EF paternal and LF maternal lines. On the basis of test-cross for the selection of LF homozygous (KK) males in the maternal line, we confirmed that three of 40 chickens were homozygous males. The survival rate, body weight, days at first egg-laying, hen-day egg production, and egg weight were analyzed to compare the production performance of EF and LF chickens. The results revealed that EF chickens were characterized by a superior survival rate, whereas LF chickens were superior in terms of egg production rate. However, no differences between LF and EF chickens were detected with respect to other production performance parameters. In addition, assessment of the fitness of sexed chicks produced in the established KNC feather-sexing lines revealed that the accuracy of sexing was 98.6%. Collectively, these findings indicate the feasibility of constructing effective KNC feather-sexing lines with potential industrial application.

• Journal of Life Science
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• v.32 no.7
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• pp.501-509
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• 2022

Pollen corrected from Quercus species is abundant in Korea and has been used to treat anemia and inflammation of the prostate gland. It is also used for hemostasis in oriental medicine. In this study, the ethanol extract of the acorn pollen and its subsequent organic solvent fractions using hexane, ethylacetate, butanol, and water residue were prepared, and their antioxidant, anti-thrombosis, and hemolysis activities were evaluated. The ethylacetate fraction of acorn pollen (EF-AP) showed the highest polyphenol content (225.0 mg/g) and strong antioxidant activity among the solvent fractions. The RC₅₀ of EF-AP against DPPH, ABTS, and nitrite radicals was 72.2, 27.7, and 62.6 ㎍/ml, respectively. The blood coagulation activities of the all-solvent fractions determined by thrombin time, prothrombin time, and activated partial thromboplastin time were negligible up to 5 mg/ml. Platelet aggregation inhibitory activities were observed in the EF-AP, butanol fraction, and water residue, whereas hexane fraction induced strong platelet aggregation. The EF-AP has no hemolysis activity against human RBC up to 1 mg/ml. UPLC/MS/MS analysis of the EF-AP revealed that rutin, isoquercitrin, and astragalin are major compounds for antioxidant and anti-thrombosis activities. Our results suggest that EF-AP could be developed as a noble antioxidant and anti-thrombosis agent.

• The KIPS Transactions:PartD
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• v.11D no.1
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• pp.163-172
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• 2004

In the software development project applying object-oriented development methodology, the research on the UCP(Use Case Point) as a method to estimate development effort is being carried on. The existing research proposes the linear model calculating the development effort that multiplies an invariant on AUCP(Adjusted Use Case Point) which applied technical and environmental factors. However, the statistical model that estimates the development effort using AUCP and UUCP(Unadjusted Use Case Point) is not being studied. The irrelevant relationship of the linear regression model, whose development period is increasing tremendously as the software size increases, is confirmed. Moreover, during the UCP calculating process, there can be errors in FP by applying the TCF(Technical Complexity Factor) and EF(Environmental Factor). This paper presents a non-linear regression model, that does not consider the TCF and EF, and that estimate the development effort from UUCP directly by utilizing the exponential function. An exponential function is selected among the linear, logarithm, polynomial, power, and exponential model via statistical evaluations of the models mentioned above.

• Journal of the Korean Mathematical Society
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• v.51 no.3
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• pp.463-472
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• 2014

Let R be a ring with identity 1, I(R) be the set of all nonunit idempotents in R and $S_{\ell}$(R) (resp. $S_r$(R)) be the set of all left (resp. right) semicentral idempotents in R. In this paper, the following are investigated: (1) $e{\in}S_{\ell}(R)$ (resp. $e{\in}S_r(R)$) if and only if re=ere (resp. er=ere) for all nilpotent elements $r{\in}R$ if and only if $fe{\in}I(R)$ (resp. $ef{\in}I(R)$) for all $f{\in}I(R)$ if and only if fe=efe (resp. ef=efe) for all $f{\in}I(R)$ if and only if fe=efe (resp. ef=efe) for all $f{\in}I(R)$ which are isomorphic to e if and only if $(fe)^n=(efe)^n$ (resp. $(ef)^n=(efe)^n$) for all $f{\in}I(R)$ which are isomorphic to e where n is some positive integer; (2) For a ring R having a complete set of centrally primitive idempotents, every nonzero left (resp. right) semicentral idempotent is a finite sum of orthogonal left (resp. right) semicentral primitive idempotents, and eRe has also a complete set of primitive idempotents for any $0{\neq}e{\in}S_{\ell}(R)$ (resp. 0$0{\neq}e{\in}S_r(R)$).

• Biomolecules & Therapeutics
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• v.8 no.2
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• pp.153-159
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• 2000

A novel serine/threonine protein phosphatase with EF-hand motif, which belongs to PPEF family was partially cloned from rat brain cDNA by employing RT-PCR method. The size of the amplified clone was 1.6kbp. The amplified DNA was subcloned into pGEM-T-Easy vector and the resulting plasmid was maned as pGEM-rPPEF2. The nucleuotide sequence is shared by 88% with that of mouse PPEF-2 cDNA, and the deduced amino acid sequence reveal 92% homology with that of mouse PPEF-2 cDNA. The N-terminal region of the cloned rat brain PPEF contains a putative phosphatase catalytic domain (PP domain) and the C-terminal region contains multiple $Ca^{2+}$ binding sites (EF region). The putative catalytic domin (PP) and the EF-hand motif (EF) regions were subcloned into pGEX4T-1 and were overexpressed in E. coli DH5 as glutathione-S-transferase (GST) fusion proteins. Expression of the desired fusion protein was identified by SDS-PAGE and also by immunoblot analysis using monoclonal antibody against GST. The recombinant proteins were purified by glutathione-agarose chromatography. This report is first to demonstrate the cloning of PPEF family from rat brain tissues. The clone reported here would be invaluable for the investigation of the role of this new type-phosphatase in rat brain.

• Journal of the Korean GEO-environmental Society
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• v.19 no.11
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• pp.15-22
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• 2018

The main objective of this study was to analyse heavy metals in sediments obtained from Gwangan bridge and to evaluate pollution intensity of the sites. To evaluate pollution intensity of the sites, we used enrichment factor (EF), geoaccumulation index, potential ecological risk factor (PERF), and mean PEL quotient. Pollution intensities of these sites were evaluated by above methods, and we found most dangerous heavy metal and polluted sites. All sites showed non polluted or low risk for the heavy metals such as Cr, Cu, Ni, Pb, and Zn, but all sites were categorized as minor enrichment for Cd. G4 was evaluated as moderately polluted by Cd ($I_{geo}$) but other sites were unpolluted by heavy metals. In summary, Cd was found to be higher concentrations for all sites. For G4 and G5 sites, Pb and Zn in addition to Cd were higher than other sites.