• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2022.05a
• /
• pp.12-14
• /
• 2022

One of the most negative social changes of the last decade is population aging which leads to 19 times more patients with Mild Cognitive Disorder(MCI). It is well established that MCI is the most important state that can prevent dementia with early diagnosis and intervention. However, the social security system for patients with dementia is not working properly due to the coronavirus pandemic and the limited human power. This article proposes design principles for dementia training programs of extended reality devices. and The findings in this study provide a guide for considering the cognitive and physical and social functions of patients.

• Child Health Nursing Research
• /
• v.29 no.3
• /
• pp.218-228
• /
• 2023

Purpose: This study aimed to identify clinical characteristics of South Korean pediatric inflammatory bowel disease (IBD) in a children's hospital over the past 5 years, with a specific focus on comparing the features observed between Crohn's disease (CD) and ulcerative colitis (UC). Additionally, it aimed to examine the nursing diagnoses given to patients. Methods: This retrospective study analyzed the medical records of Korean pediatric patients under 18 years of age who were diagnosed with IBD and hospitalized at a children's hospital in Seoul, South Korea, from January 2017 to December 2021. Results: The number of pediatric patients diagnosed with IBD steadily increased. This finding was particularly prominent for CD patients, the majority of whom were male. Pediatric patients with CD had significantly higher rates of abdominal pain and perianal lesions, while pediatric patients with UC had a higher rate of bloody stool. Laboratory findings indicated that CD patients had higher levels of inflammatory markers and lower albumin levels than UC patients. The nursing diagnoses given during hospitalization mostly related to safety and protection, physical comfort, and gastrointestinal function. Conclusion: This study provides insights into Korean pediatric IBD patients, enabling early detection and the development of nursing intervention strategies. From a comprehensive perspective, nursing care should not only address patients' physical needs but also their psychosocial needs.

• PNF and Movement
• /
• v.20 no.1
• /
• pp.1-8
• /
• 2022

Purpose: The purpose of this study was to investigate the effect of blood flow restriction bridge exercise on leg muscle thickness and balance. In addition, it is to promote blood flow restriction exercise as the basis for early prevention, diagnosis, and treatment of sarcopenia in clinical practice. Methods: Twenty elderly women aged 65 years or older were selected to participate in this study. The subjects were divided into two groups of 10: one with blood flow restriction with bridge exercise (BFRG) and the other with bridge exercise alone (BG). As for the exercise method, the thickness of rectus femoris and vastus medialis and Berg balance scale were investigated by intervention for 30 minutes a day, 3 times a week, for a total of 6 weeks. Results: There was significant difference in the thickness of the rectus femoris and vastus medial and within-group changes in the Berg balance scale (p <0.05) before and after the experiment in the BFRG and BG groups (p<0.05). There was a significant difference in change between the two groups (p <0.05). Conclusion: There was a significant difference in the intragroup change of the Berg balance scale in the BFRG before and after the experiment, but there was no significant difference in the BG, and there was no significant difference in the change between the two groups.

• Journal of Genetic Medicine
• /
• v.20 no.2
• /
• pp.31-38
• /
• 2023

Rare diseases, even though defined as fewer than 20,000 in South Korea, with over 8,000 rare Mendelian disorders having been identified, they collectively impact 6-8% of the global population. Many of the rare diseases pose significant challenges to patients, patients' families, and the healthcare system. The diagnostic journey for rare disease patients is often lengthy and arduous, hampered by the genetic diversity and phenotypic complexity of these conditions. With the advent of next-generation sequencing technology and clinical implementation of exome sequencing (ES) and genome sequencing (GS), the diagnostic rate for rare diseases is 25-50% depending on the disease category. It is also allowing more rapid new gene-disease association discovery and equipping us to practice precision medicine by offering tailored medical management plans, early intervention, family planning options. However, a substantial number of patients remain undiagnosed, and it could be due to several factors. Some may not have genetic disorders. Some may have disease-causing variants that are not detectable or interpretable by ES and GS. It's also possible that some patient might have a disease-causing variant in a gene that hasn't yet been linked to a disease. For patients who remain undiagnosed, reanalysis of existing data has shown promises in providing new molecular diagnoses achieved by new gene-disease associations, new variant discovery, and variant reclassification, leading to a 5-10% increase in the diagnostic rate. More advanced approach such as long-read sequencing, transcriptome sequencing and integration of multi-omics data may provide potential values in uncovering elusive genetic causes.

• Journal of Chest Surgery
• /
• v.57 no.1
• /
• pp.87-91
• /
• 2024

Gunshot-induced chest trauma is exceedingly rare among civilians in South Korea due to strong firearm control policies. In contrast to military reports emphasizing the use of emergent open thoracotomy to increase chances of survival, most penetrating non-cardiac injuries in civilian settings are managed conservatively, such as through chest tube insertion, as they typically result from lower-energy bullets. However, early surgical intervention for penetrating gunshot wounds can help reduce delayed fatalities caused by septic complications from pneumonia or empyema. The advent of minimally invasive thoracic surgery has provided cost-effective and relatively non-invasive treatment options, aided in the prevention of potential complications from undrained hematomas, and facilitated functional recovery and reintegration into society. We successfully treated a patient with a penetrating gunshot wound to the chest using video-assisted thoracoscopic surgery.

• Journal of Korean Academy of Rural Health Nursing
• /
• v.18 no.2
• /
• pp.73-79
• /
• 2023

Purpose: This study describes how public health officials running clinic-centered around "Our Village's Pretty Dementia Shelter" improved their ability to cope with dementia and health by implementing early dementia screening and cognitive intervention programs. Methods: This study targeted 11 hopeful seniors from 6 villages, who were residents of the area under the jurisdiction of Health Clinic B located in County A, were over 65 years of age, and had not experienced Our Village's Pretty dementia shelters. Results: The results of the Cognitive Screening Test (CIST) showed that scores improved on all evaluation items and depression decreased. Through the dementia prevention program, health improved, vitality increased through leisure activities and cultural experiences in daily life, and the quality of life improved. Aadditionally, participating with close neighbors has become an activity that can make dementia prevention activities a habit and widespread practice. Conclusion: This case demonstrate the need for continued implementation of dementia prevention and health promotion programs for rural residents. Accordingly, it is necessary to continuously operate dementia prevention programs by diversifying them and securing expertise from rural nurses.

• Clinical Endoscopy
• /
• v.57 no.1
• /
• pp.73-81
• /
• 2024

Background/Aims: Upper gastrointestinal bleeding (UGIB) is a life-threatening condition that necessitates early identification and intervention and is associated with substantial morbidity, mortality, and socioeconomic burden. However, several diagnostic challenges remain regarding risk stratification and the optimal timing of endoscopy. The PillSense System is a noninvasive device developed to detect blood in patients with UGIB in real time. This study aimed to assess the safety and performance characteristics of PillSense using a simulated bleeding model. Methods: A preclinical study was performed using an in vivo porcine model (14 animals). Fourteen PillSense capsules were endoscopically placed in the stomach and blood was injected into the stomach to simulate bleeding. The safety and sensitivity of blood detection and pill excretion were also investigated. Results: All the sensors successfully detected the presence or absence of blood. The minimum threshold was 9% blood concentration, with additional detection of increasing concentrations of up to 22.5% blood. All the sensors passed naturally through the gastrointestinal tract. Conclusions: This study demonstrated the ability of the PillSense System sensor to detect UGIB across a wide range of blood concentrations. This ingestible device detects UGIB in real time and has the potential to be an effective tool to supplement the current standard of care. These favorable results will be further investigated in future clinical studies.

• Clinical Endoscopy
• /
• v.55 no.1
• /
• pp.95-100
• /
• 2022

Background/Aims: Endoscopic mucosal resection (EMR) is the primary treatment for duodenal adenomas; however, it is associated with a high risk of perforation and bleeding, especially with larger lesions. The goal of this study was to demonstrate the feasibility and safety of endoscopic suturing (ES) for the closure of mucosal defects after duodenal EMR. Methods: Consecutive adult patients who underwent ES of large mucosal defects after EMR of large (>2 cm) duodenal adenomas were retrospectively enrolled. The OverStitch ES system was employed for closing mucosal defects after EMR. Clinical outcomes and complications, including delayed bleeding and perforation, were documented. Results: During the study period, ES of mucosal defects was performed in seven patients in eight sessions (six for prophylaxis and two for the treatment of perforation). All ES sessions were technically successful. No early or delayed post-EMR bleeding was recorded. In addition, no clinically obvious duodenal stricture or recurrence was encountered on endoscopic follow-up evaluation, and no patients required subsequent surgical intervention. Conclusions: ES for the prevention and treatment of duodenal perforation after EMR is technically feasible, safe, and effective. ES should be considered an option for preventing or treating perforations associated with EMR of large duodenal adenomas.

• Journal of Cerebrovascular and Endovascular Neurosurgery
• /
• v.25 no.4
• /
• pp.429-433
• /
• 2023

84 years old gentle man with past medical history of hypertension and diabetes presented with sudden onset right sided weakness and aphasia for two hours. Initial neurological assessment revealed National Institute of Health Stroke Scale (NIHSS) 17. Computed tomography (CT) scan demonstrated minimal early ischemic changes along left insular cortex with occlusion of left middle cerebral artery (MCA). Based on clinical and imaging findings, decision was made to perform mechanical thrombectomy procedure. Initially, right common femoral artery approach was utilized. However, due to unfavorable type-III bovine arch, left internal carotid artery could not be engaged via this approach. Subsequently, access was switched to right radial artery. Angiogram revealed small caliber radial artery, with larger caliber ulnar artery. Attempt was made to advance the guide catheter through the radial artery, however significant vasospasm was encountered. Subsequently, ulnar artery was accessed and successful thrombolysis in cerebral infarction (TICI) III left MCA reperfusion was achieved with a single pass of mechanical thrombectomy via this approach. Post procedure neurological examination demonstrated significant clinical improvement. Doppler ultrasound 48 hours after the procedure demonstrated patent flow in radial and ulnar arteries with no evidence of dissection.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.51 no.3
• /
• pp.310-320
• /
• 2024

Impaction of the tooth can cause functional and esthetic problems, so early intervention is critical. This report describes two cases of orthodontic traction of impacted mandibular canine and mandibular premolar teeth using a modified mandibular lingual arch soldered with traction hooks rather than a conventional orthodontic appliance. By planning the position and shape of the traction hooks with consideration for the three-dimensional position and angulation of the impacted teeth, clinicians can apply the intended direction and magnitude of traction force. Furthermore, this appliance can be used for multiple impacted teeth in various locations within the mandibular arch by modifying the position and shape of the traction hooks.