• Title/Summary/Keyword: early ages

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Changing Trends of Colorectal Carcinoma in Nepalese Young Adults

  • Kansakar, Prasan;Singh, Yogendra
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3209-3212
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    • 2012
  • Introduction: Colorectal carcinoma (CRC) is the most common gastrointestinal malignancy in the older population, but it is also quite frequent among young adults in developing countries. The aim of this study was to update the trends of clinicopathological features of CRC in young Nepalese. Methods: A retrospective comparative study on the data retrieved from the surgical records of all patients between 20 to 39 years of age with CRC was carried out for periods of 5 years each from 1999 to 2003 (early) and 2004 to 2008 (recent), treated at Tribhuvan University Teaching Hospital, Kathmandu, Nepal. Results: The number of young adults with CRC increased from 28 to 34. However, the proportion of young patients in both groups was 28% of all CRC patients. The mean ages were $34{\pm}4.7$ and $31.8{\pm}5.1$ years in early and recent 5 years, respectively, and the male female ratio changed from 2:3 to 4:3. Abdominal pain as the most common presenting symptom was replaced by bleeding per rectum in recent years. The mean duration from onset of symptoms to seeking medical advice decreased from 7.8 months to 5.6 months in recent years. More patients (85.3%) were subjected to endoscopic examination in recent years than early years (60.7%) and right colonic cancer increased from 10.7% to 26.5%. However, the rectum was the commonest site in both early (71.4%) and recent (50%) groups. CRC was detected significantly at an earlier stage (7.1% vs 32.4%) in recent years with large proportion of modified Dukes B stage. Poorly differentiated adenocarcinoma was the predominant histology in both groups (50% vs 60.7%). Curative resection had risen in recent years (39.3% vs 73.6%). Conclusion: CRC among Nepalese young adults accounts for a high incidence (28%) of all CRC cases. Although right sided colonic cancer has been increasing, rectum is the commonest site. There is also an increasing trend for diagnosis at earlier stages of the disease which can be treated with curative intent.

Estimates of Early Selection Efficiency for Height Growth Using Age-Age Correlation in Pinus koraiensis (수령간 상관을 이용한 잣나무 수고 생장의 조기선발 효율 추정)

  • Han, Sang-Urk;Yi, Jae-Son
    • Journal of Korean Society of Forest Science
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    • v.84 no.3
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    • pp.356-360
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    • 1995
  • Korean white pine(Pinus koraiensis S.et Z.) is one of the important silvicultural species due to its quality timber in addition to edible pine - nut production. Selective breeding method is under progress to improve growth and nut production for this species. This study was carried out to obtain genetic information necessary for establishing advanced generation seed orchard, such as genetic parameters and efficiency of early selection. Open - pollinated cones were collected from 50 plus trees. In the spring of 1986, test plantations were established at 3 different sites with 4 - year - old seedlings. Seedling height was measured from age 5 to 10 in plantations. Genetic and phenotypic correlations based on the log of the ratio of two ages (LAK) were expressed as simple regression with statistical significance($r^2=0.7862$ and 0.8256, respectively). If 20 years is presumed to mature, the most efficient age for early selection is 3 years after planting with efficiency of 1.96.

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Long Term Results After Repair of Postmyocardial Infarction Ventricular Septal Defect (심근경색후 발생한 심실중격 결손의 외과적 치료후 장기결과)

  • 유경종
    • Journal of Chest Surgery
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    • v.27 no.12
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    • pp.989-994
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    • 1994
  • Between January 1986 and August 1993, 11 patients underwent surgical repair of ventricular septal defect [VSD] complicated with myocardial infarction. The ages of patients were ranged from 22 years to 83 years with a mean of 64 years. There were 8 male and 3 female patients. The preoperative cineangiograms of all patients were reviewed to measure both ventricular function and to evaluate coronary artery disease. The mean time interval between occurance of VSD and operation was 13 days. The operations were performed as soon as possible if there were hemodynamic derangement. Postmyocardial infarction VSD were repaired simultaneuously with coronary artery bypass graft in 3 patients, repaired with left ventricular aneurysmectomy in 6 patients, with left ventricular thrombectomy in 1 patient and with mitral valve chordae repair in 1 patient. There was no early death [within 30 days]. There were 6 postoperative complications; one with perioperative myocardial infarction, two with recurred VSD on postoperative 1 and 6 days respectively, two with lower leg embolism associated with intraaortic balloon pump insertion, one with wound infection. Of the complicated patients, 1 patient with lower leg embolism performed left above ankle amputation. Among two patients with recurred ventricular septal defect, one patient is doing well without problem. On follow up echocardiogram, the residual VSD was occluded completely. However another patient was with recurred VSD died 3 months after the operation because of congestive heart failure. Of the long term survivors, all patients are in NEW YORK Heart Association functional Class I or II. Although number of patients were small, our results of surgical closure of postmyocardial infarction VSD were favored to the others. Moreover, seven patients with preoperative cardiogenic shock among 11 were performed early operation after diagnosis of ventricular septal rupture. All of the patients were survived and doing well during the follow up period. Therefore early diagnosis with aggressive preoperative care with intraaortic balloon pumping and early operation seems to be very important for prevention of deterioration of vital organ.

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Early Eruption of Maxillary Permanent Canines : Report of 2 Cases (상악 영구 견치의 조기 맹출 : 증례보고)

  • Oh, Nakyeong;Lee, Jaesik;Nam, Soonhyeun;Kim, Hyunjung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.45 no.4
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    • pp.514-520
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    • 2018
  • Congenital absence of the primary canines is very rare. Congenital absence of primary teeth often causes their successors to not develop at all or affects the eruption of their successors. The purpose of this paper was to report the cases of 2 children with early eruption of the maxillary permanent canines at ages 4 and 6 years, respectively, following congenital absence of their maxillary primary canines, which are not common in earlier studies. Although tooth eruption and shedding exhibit some physiological variation, certain clinical cases are extreme. Premature eruption of the maxillary permanent canines may cause complications in terms of the space available for the eruption of adjacent teeth. Additionally, early eruption of permanent teeth increases the need for more careful oral hygiene. Therefore, the pediatric dentist must be alert to such rare cases.

The Order of Appetites in Early Modern England: Shakespeare's Signs of Food and Social Mobility (초기 근대 영국의 미각의 질서 -셰익스피어 희곡의 음식 기호와 사회적 유동성)

  • Roh, Seung-Hee
    • Journal of English Language & Literature
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    • v.57 no.1
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    • pp.171-190
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    • 2011
  • Shakespeare's plays deploy an interesting array of food signs in a way to illuminate the historical process of what Stephen Mennell has described as "the civilizing of appetite"-a process in which the changes of food choices and eating habits took place in response to the changes in people's way of life and personality structure over the long-term modern period since the middle ages. Shakespeare's plays suggest that the civilizing of appetite in early modern England was heavily affected by the forces of social mobility as well as the nascent market economy. The Capulets' costly preparation of Juliet's wedding banquet is a showcase of conspicuous consumption which was a structural necessity for the ruling class in Shakespeare's time. Some fifteen years later, the same kinds of foodstuffs are included in a shepherd's shopping list for the sheepshearing festival in Winter's Tale. This is a significant coincidence to prove that food was an important source of emulation and contest among different social classes; and that the rich diet of the upper class gave impetus to social mobility. The Elizabethan subjects, especially among the elite noblemen, were interpellated by the ideology of food that equated the quality of food and the eater's social identity. Faced with bankruptcy as a consequence of his extravagant consumption habit, Bassanio in The Merchant of Venice testifies to the gripping ideology of food onto early modern people, while Poor Tom in King Lear presents a comic parody of the rich people's conspicuous waste. Also in Coriolanus and The Merry Wives of Winsor, Shakespeare uses food as a metaphor for class-motivated social struggles.

Mix Design Conditions at Early Curing Age of PCS-Coating Material Effected on Improvement in Bond Strength of Coated Rebar (도장철근의 부착강도 개선에 영향을 미치는 초기재령에서의 PCS 도장재 배합조건)

  • Jo, Young-Kug;Park, Dong-Yeol;Kim, Wan-Ki
    • Journal of the Korea Concrete Institute
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    • v.25 no.1
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    • pp.73-80
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    • 2013
  • Polymer cement slurry (PCS) made from organic polymer dispersion and cement has good adhesion to steel, waterproofness and acid resistance due to being of polymer films formed in cement slurry. The purpose of this study is to evaluate the mix design conditions at early curing age of PCS-coating material effected on improvement in bond strength of coated rebar. The test pieces are prepared with two types of polymer dispersions such as St/BA and EVA, four polymer-cement ratios, two types of cement, four coating thicknesses and three curing ages, and tested for the bond strength test. From the test results, in general, bond strength of PCS-coated rebar is better than that of uncoated rebar and epoxy-coated rebar. It is also high bond strength at curing ages of 7-day or less, and coating thicknesses of $75{\mu}m$ and $100{\mu}m$. The maximum bond strength of PCS-coated rebar at curing age of 3-hour is almost same as that of curing age of 1-day and 7-day. The maximum bond strength of PCS-coated rebar with ultra high-early strength cement and St/BA at polymer-cement ratio of 80%, and coating thickness of $100{\mu}m$ is about 1.52 and 1.58 times respectively, the strength of uncoated rebar and epoxy-coated rebar. It is apparent that the curing age, coating thickness, type of polymer and cement are very important factors to improve the bond strength of PCS-coated rebar to cement concrete. We can have basic information that PCS-coated rebar with curing age at 3-hour and coating thickness of $100{\mu}m$ can replace epoxy-coated rebar.

A Study on Scientific Concepts and Teaching and Learning Methods in the Activities of the Nuri Curriculum Teacher Guidebooks for Ages 3-5 in Accordance with Themes (생활주제를 중심으로 본 3-5세 연령별 누리과정 교사용지도서 활동의 과학개념 및 교수학습방법 분석)

  • Choi, Hye Yoon
    • Korean Journal of Child Education & Care
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    • v.18 no.4
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    • pp.65-89
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    • 2018
  • Objective: The purpose of this study is to analyze the science concepts and teaching and learning methods presented in the science education-related activities of the Nuri Curriculum teacher guidebooks for ages 3-5. Methods: The research data included 772 activities related to science education in the teachers' guidebook. The analysis of science concepts was based on physical science (force and motion, physical structure, electricity and magnetism, light and shadow, sound properties), chemistry (material properties, material reaction), life science (organizational structure, growth and change, heredity and evolution, animal plant and human relationships), earth science (earth system interaction, earth system structure, and universe), engineering (designed world, engineering design, engineering, technology and society) and ecology (environment preservation). Teaching and learning methods were analyzed according to the types of small and large group activities and of free play activities. Results: Science concepts were mainly presented in the fields of engineering, chemistry, and life science commonly among children aged 3-5, whereas the concepts of physical science were lowly presented in all ages. Science concepts appeared mainly in the daily subjects of 'animal plant and nature', 'life tools', 'environment and life', and 'spring, summer, autumn and winter'. As the teaching and learning method, free paly activities (science area, free outdoor selection activity, math and manipulative activity) were mostly used for the ages of 3 and 4, and small and large group activities (cooking, story sharing, music activity) were for the age of 5. Conclusion/Implications: It is necessary to select the level of science area and concept that can be taught according to the age of children and the timing of the teaching.

Effect of Iron Ore Tailings Replacing Porous Basalt on Properties of Cement Stabilized Macadam

  • Qifang Ren;Fan Bu;Qinglin Huang;Haijun Yin;Yuelei Zhu;Rui Ma;Yi Ding;Libing Zhang;Jingchun Li;Lin Ju;Yanyan Wang;Wei Xu;Haixia Ji;Won-Chun Oh
    • Korean Journal of Materials Research
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    • v.34 no.6
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    • pp.291-302
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    • 2024
  • In this paper, iron ore tailings (IOT) were separated from the tailings field and used to prepare cement stabilized macadam (CSM) with porous basalt aggregate. First, the basic properties of the raw materials were studied. Porous basalt was replaced by IOT at ratios of 0, 20 %, 40 %, 60 %, 80 %, and 100 % as fine aggregate to prepare CSM, and the effects of different cement dosage (4 %, 5 %, 6 %) on CSM performance were also investigated. CSM's durability and mechanical performance with ages of 7 d, 28 d, and 90 d were studied with the unconfined compression strength test, splitting tensile strength test, compressive modulus test and freeze-thaw test, respectively. The changes in Ca2+ content in CSM of different ages and different IOT ratios were analyzed by the ethylene diamine tetraacetic acid (EDTA) titration method, and the micro-morphology of CSM with different ages and different IOT replaced ratio were observed by scanning electron microscopy (SEM). It was found that with the same cement dosage, the strengths of the IOT-replaced CSM were weaker than that of the porous basalt aggregate at early stage, and the strength was highest at the replaced ratio of 60 %. With a cement dosage of 4 %, the unconfined compressive strength of CSM without IOT was increased by 6.78 % at ages from 28 d to 90 d, while the splitting tensile strength increased by 7.89 %. However, once the IOT replaced ratio reached 100 %, the values increased by about 76.24 % and 17.78 %, which was better than 0 % IOT. The CSM-IOT performed better than the porous basalt CSM at 90 d age. This means IOT can replace porous basalt fine aggregate as a pavement base.

Estiniation of Genetic Parameters for Body Weight, Shank Length, and Shank Width in Korean Pheaaant (한국꿩의 체중과 정강이 길이 및 정강이 두께에 대한 유전모수 추정에 관한 연구)

  • Kim, J.;Yang, Y.H.
    • Korean Journal of Poultry Science
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    • v.24 no.3
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    • pp.153-160
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    • 1997
  • This study was carried out to estimate the heritability and genetic correlation for body weight, shank length and shank width at various wk of age in growing Korean pheasant. All the measurements were done from one day to 20 wk of age with 4 wk interval. The heritability estimates for body weight were in the range of 0.54~0.59 for male and of 0.49~0.81 for female from 4 to 20 wk of age. The heritability estimates of male and female were in the range of 0.38~0. 82 and 0.41~0.67 for shank length, and of 0.48~0.88 and 0.49~0.71 for shank width, respectively. Genetic and phenotypic correlation coefficients between the measurements at different ages in each trait of body weight, shank length and shank width were medium to high positive values. Because the estimates of heritabilities and genetic correlations were high, the genetic gain for body weight is expected by either a direct selection or an early selection based on the record of early growing stage.

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Assessment of Basic Physical Activity According to Sex and Age Groups in Elderly Groups in an Urban Community (도시 노인의 성별 및 연령별 기초신체활동 측정 평가)

  • Kim, So-Min;Kim, Dae-Kyung
    • PNF and Movement
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    • v.16 no.2
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    • pp.239-248
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    • 2018
  • Purpose: This study aimed to examine the elderly physical fitness test for elderly people living in urban areas and to evaluate the physical fitness level according to gender and age groups. Methods: The subjects were 180 elderly people aged 65 and over living in urban areas. The elderly people were classified into early old age, middle old age, and advanced old age groups. Five items of the physical fitness test for the elderly (arm curl, chair stand, 2 min step test, back scratch, and chair sit and reach). Results: In analyzing the average of each item by gender and age, a significant difference was found in the results of each item as age increased in all sports, but no difference was observed according to gender except dumbbell lifting. Conclusion: Although the physical fitness level of all ages decreased from early age to late age, the difference in physical fitness according to gender was not significant except the arm curl test. The results of this study can be used as basic data for a new "age-specific exercise program" for the elderly.