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Quality Control of Adenophorae Radix (사삼의 품질 관리에 관한 연구)

  • Park, Yun-Kyung;Yoo, Hye-Hyun;Baek, Seung-Hoon;Lee, Seung-Ho;Kim, Chang-Min;Lee, Kyung-Soon;Park, Man-Ki;Park, Jeong-Hill
    • Korean Journal of Pharmacognosy
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    • v.34 no.1 s.132
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    • pp.10-13
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    • 2003
  • This study is to establish the quality control method of Adenophorae Radix. (6R,7R)-E,E-tetradeca-4,12-diene-8,10-diyne-1,6,7-triol (1) isolated from this plant was adequate as an analytical marker. Content of 1 in Adenophorae Radix was $0.006\;{\pm}\;0.003%$ (n = 43). In addition, total ash content was $6.5\;{\pm}\;4.0%$, and loss on drying was $12.1\;{\pm}\;2.1%$.

The Line n-sigraph of a Symmetric n-sigraph-V

  • Reddy, P. Siva Kota;Nagaraja, K.M.;Geetha, M.C.
    • Kyungpook Mathematical Journal
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    • v.54 no.1
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    • pp.95-101
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    • 2014
  • An n-tuple ($a_1,a_2,{\ldots},a_n$) is symmetric, if $a_k$ = $a_{n-k+1}$, $1{\leq}k{\leq}n$. Let $H_n$ = {$(a_1,a_2,{\ldots},a_n)$ ; $a_k$ ${\in}$ {+,-}, $a_k$ = $a_{n-k+1}$, $1{\leq}k{\leq}n$} be the set of all symmetric n-tuples. A symmetric n-sigraph (symmetric n-marked graph) is an ordered pair $S_n$ = (G,${\sigma}$) ($S_n$ = (G,${\mu}$)), where G = (V,E) is a graph called the underlying graph of $S_n$ and ${\sigma}$:E ${\rightarrow}H_n({\mu}:V{\rightarrow}H_n)$ is a function. The restricted super line graph of index r of a graph G, denoted by $\mathcal{R}\mathcal{L}_r$(G). The vertices of $\mathcal{R}\mathcal{L}_r$(G) are the r-subsets of E(G) and two vertices P = ${p_1,p_2,{\ldots},p_r}$ and Q = ${q_1,q_2,{\ldots},q_r}$ are adjacent if there exists exactly one pair of edges, say $p_i$ and $q_j$, where $1{\leq}i$, $j{\leq}r$, that are adjacent edges in G. Analogously, one can define the restricted super line symmetric n-sigraph of index r of a symmetric n-sigraph $S_n$ = (G,${\sigma}$) as a symmetric n-sigraph $\mathcal{R}\mathcal{L}_r$($S_n$) = ($\mathcal{R}\mathcal{L}_r(G)$, ${\sigma}$'), where $\mathcal{R}\mathcal{L}_r(G)$ is the underlying graph of $\mathcal{R}\mathcal{L}_r(S_n)$, where for any edge PQ in $\mathcal{R}\mathcal{L}_r(S_n)$, ${\sigma}^{\prime}(PQ)$=${\sigma}(P){\sigma}(Q)$. It is shown that for any symmetric n-sigraph $S_n$, its $\mathcal{R}\mathcal{L}_r(S_n)$ is i-balanced and we offer a structural characterization of super line symmetric n-sigraphs of index r. Further, we characterize symmetric n-sigraphs $S_n$ for which $\mathcal{R}\mathcal{L}_r(S_n)$~$\mathcal{L}_r(S_n)$ and $$\mathcal{R}\mathcal{L}_r(S_n){\sim_=}\mathcal{L}_r(S_n)$$, where ~ and $$\sim_=$$ denotes switching equivalence and isomorphism and $\mathcal{R}\mathcal{L}_r(S_n)$ and $\mathcal{L}_r(S_n)$ are denotes the restricted super line symmetric n-sigraph of index r and super line symmetric n-sigraph of index r of $S_n$ respectively.

INTEGRAL BASES OVER p-ADIC FIELDS

  • Zaharescu, Alexandru
    • Bulletin of the Korean Mathematical Society
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    • v.40 no.3
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    • pp.509-520
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    • 2003
  • Let p be a prime number, $Q_{p}$ the field of p-adic numbers, K a finite extension of $Q_{p}$, $\bar{K}}$ a fixed algebraic closure of K and $C_{p}$ the completion of K with respect to the p-adic valuation. Let E be a closed subfield of $C_{p}$, containing K. Given elements $t_1$...,$t_{r}$ $\in$ E for which the field K($t_1$...,$t_{r}$) is dense in E, we construct integral bases of E over K.

r-Learning and Educational Information Policies (r-Learning과 교육정보화 정책)

  • Lee, Jong-Yun
    • Journal of the Korea Convergence Society
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    • v.1 no.1
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    • pp.1-15
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    • 2010
  • The Education has responsibility for predicting the social changes and cultivating global talent which the society needs. The ministry of education, science and technology in govern ment has been the concerns on social educational changes and thus built the '5 31 educational reform policy' in 1995 by the educational reform committee. As a solution of a social change, this paper reviews the three-phase educational information policies, and e-learning and u-learning which are the main technologies in educational information. Also, the technologies of e-learning can be divided into m-learning, t-learning, u-learning, r-learning, game-based learning according to the contents mass media. Among them, this paper introduces the concept of robot-learning, called r-learning, and compares it with u-learning.

Free-Radical Copolymerization of Glycidyl Methacrylate with Phthalimidoethyl Acrylate : Synthesis and Determination of Monomer Reactivity Ratios (GMA와 프탈이미드아크릴레이트의 공중합체 합성과 반응성비)

  • Oh, Seung-Min;Oh, Dae-Hee
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.2
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    • pp.297-304
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    • 2013
  • Free-radical copolymerization of glycidyl methacrylate(GMA) and N-phthalimidoethyl acrylate(NPEA) were carried out at $60^{\circ}C$ in dimethylformamide(DMF) solution in the presence of benzoylperoxide(BPO) at low conversion. The polymers were characterized by IR and $^1H$-NMR. The compositions of the copolymer was analyzed by ultra violet(UV/Vis) spectrophotometry. The reactivity ratios of the monomer was determined by the application of Fineman-Ross(FR) and Kelen-T$\ddot{u}$d$\ddot{o}$s(KT) methods. The monomer reactivity ratios of the system and Alfrey-Price's resonance effect(Q) and polar effect(e) value for NIEA were determined as follow. The reactivity ratios of the monomer obtained from FR and KT are found to be $r_1$=0.87, $r_2$=0.98 and $r_1$=0.88, $r_2$=0.99 respectively. The Q and e values of poly(GMA-co-NPEM) calculated from $r_1$ and $r_2$ was Q= 1.31, e=0.75 respectively.

A Study of the Optimization of the Compounded PP Using the DOE (실험계획법을 이용한 복합 폴리프로필렌의 최적화 연구)

  • Park, Sung-Ho;Lim, Dong-Cheol;Kim, Ki-Sung;Bae, Jong-Rak;Jeon, Oh-Hwan
    • Transactions of the Korean Society of Automotive Engineers
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    • v.18 no.1
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    • pp.74-85
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    • 2010
  • In order to formulate the compounded polypropylene(C-PP) which is suitable to an automotive door trim panel, 9 sorts of properties were measured after manufacturing the C-PP using an extruder and an injection machine with polypropylene(PP), ethylene-octene rubber(EOR) and talc. Mixture design, especially extreme vertices design, in DOE with MINITAB - commercial software was used to analyze the data. The relations between each property and each component, for example, $y=0.00907222x_1+0.00870556x_2+0.0155722x_3$ for specific gravity, were found out by the regression analysis and the variance analysis. The optimized formulation of the C-PP for an automotive door trim panel was acquired at PP(77.6962), EOR(11.0238) and talc(10.2800) by use of the response optimizer(mixture) in MINITAB.

Effect of Sowing Date and Mulching Materials on Growth and Yield of Scutellaria baicalensis Georg (파종기(播種期)와 피복재료(被覆材料)가 황금(黃芩)의 생육(生育) 및 수양(收量)에 미치는 영향(影響))

  • Park, Gyu-Chul;Park, Tae-Dong;Park, In-Jin;Choi, Kyong-Ju;Kim, Chang-Chul;Kim, Myung-Suck;Her, Gill-Hyun;Chung, Byong-Jun
    • Korean Journal of Medicinal Crop Science
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    • v.3 no.3
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    • pp.165-172
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    • 1995
  • This study was carried out to investigate effects of poly-ethylene (P. E.) films mulching according to the different sowing date on growth and yield of Scutellarja bakalensjs G. In sowing date at Apr. 20, the number, length, diameter and yield of root was increased. In black P. E. film mulching, the growth of shoot and root was better and weed control was more effective than open field cultivation during hot season. Therefore dry weight of root was increased by 5% at Apr. 20 as compared with Apr. 1 in P. E. film mulching and that of black P. E. film mulching cultivation was increased by 13% as compared with transparent P. E. film mulching cultivation. But in nonmulching cultivation, the yield of root was increased at Apr. 1

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MiR-99a Inhibits Cell Proliferation and Tumorigenesis through Targeting mTOR in Human Anaplastic Thyroid Cancer

  • Huang, Hou-Gang;Luo, Xi;Wu, Shuai;Jian, Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.4937-4944
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    • 2015
  • MicroRNAs (miRNAs) are emerging as critical regulators in carcinogenesis and tumor progression. Recently, miR-99a has been reported as a tumor suppressor gene in various human cancers, but its functions in the context of anaplastic thyroid cancer (ATC) remain unknown. In this study, we reported that miR-99a was commonly downregulated in ATC tissue specimens and cell lines with important functional consequences. Overexpression of miR-99a not only dramatically reduced ATC cell viability by inducing cell apoptosis and accumulation of cells at G1 phase, but also inhibited tumorigenicity in vivo. We then screened and identified a novel miR-99a target, mammalian target of rapamycin (mTOR), and it was further confirmed by luciferase assay. Up-regulation of miR-99a would markedly reduce the expression of mTOR and its downstream phosphorylated proteins (p-4E-BP1 and p-S6K1). Similar to restoring miR-99a expression, mTOR down-regulation suppressed cell viability and increased cell apoptosis, whereas restoration of mTOR expression significantly reversed the miR-99a antitumor activity and the inhibition of mTOR/p-4E-BP1/p-S6K1 signal pathway profile. In clinical specimens and cell lines, mTOR was commonly overexpressed and its protein levels were statistically inversely correlated with miR-99a expression. Taken together, our results demonstrated for the first time that miR-99a functions as a tumor suppressor and plays an important role in inhibiting the tumorigenesis through targeting the mTOR/p-4E-BP1/p-S6K1 pathway in ATC cells. Given these, miR-99a may serve as a novel prognostic/diagnostic and therapeutic target for treating ATC.

La Participation des habitants à la Constitution de Villages Touristiques Insulaires : le Cas de l'Île de Nangdo dans la Ville de Yeosu en Corée du Sud (도서지역 관광마을 조성을 위한 주민참여 방안 -여수시 낭도를 사례로-)

  • Lee, Jeong Hun
    • Journal of the Korean association of regional geographers
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    • v.22 no.1
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    • pp.86-101
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    • 2016
  • La situation de la $r{\acute{e}}gion$ rurale et maritime de la province de Jeollanam-do en $Cor{\acute{e}}e$ du sud se $caract{\acute{e}}rise$ par une relative $p{\acute{e}}nurie$ de population. Le projet 'Ces ${\hat{I}}les$ que l'on aime visiter', $g{\acute{e}}r{\acute{e}}$ par la province de Jeollanam-do, s'articule autour de villages insulaires lieux de bien- ${\hat{e}}tre$ pour viser une augmentation de la population. Il s'agit de $d{\acute{e}}velopper$ le tourisme durable en s'appuyant sur la $beaut{\acute{e}}$ des paysages naturels, l'histoire, la culture et les traditions de cette $r{\acute{e}}gion$ insulaire. Pour cela, la participation active des habitants est essentielle. Cette ${\acute{e}}tude$ a pour but de $r{\acute{e}}fl{\acute{e}}chir$ aux moyens de $d{\acute{e}}velopper$ la participation des habitants en se fondant sur une $enqu{\hat{e}}te$ $men{\acute{e}}e$ dans la campagne. Nous avons mutuellement $analys{\acute{e}}$ entre les moyens de la participation des habitants et l'apanage $d{\acute{e}}mographique$ ${\grave{a}}$ cause de leurs $r{\acute{e}}sultats$ $diff{\acute{e}}rentes$. Voici les moyens de la participation des habitants $fond{\acute{e}}s$ sur la $caract{\acute{e}}ristique$ communautaire: $l^{\prime}activit{\acute{e}}$ $r{\acute{e}}mun{\acute{e}}ratrice$ communautaire; $l^{\prime}am{\acute{e}}lioration$ de l'habitat; les loisirs dans la $r{\acute{e}}gion$. Nous proposons plusieurs exemples pour $d{\acute{e}}velopper$ des programmes $fond{\acute{e}}s$ sur la participation des habitants de $l^{\prime}{\hat{i}}le$ de Nangdo, d'un rite communautaire maritime et des programmes ${\acute{e}}ducationnels$ d'explication touristique.

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Studies on the Fishery Biology of Pomfrets, Pampus spp. in the Korean Waters 3. Age and Growth of Korean Pomfret, Pampsu echinogaster, from the East China Sea (한국근해 병어류의 자원생물학적 연구 3. 동지나해산 덕대의 연령과 성장)

  • KANG Yong Joo;LEE Dong Woo;HONG Byung Que;KIM Young Sub
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.22 no.5
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    • pp.281-290
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    • 1989
  • Growth of the Korean pomfret, Pampus echinogaster, captured in the East China Sea from January to December 1987, was estimated by annual rings on the vertebral centrum. The time of annual ring formation was approximately during September and October. Von Ber-talanffy growth equations derived from the mean back-calculated fork length(cm) at each age were as follows: for females, $L_{t}=29.17(1-e xp(-0.3213(t+0.7601)))$, for males, $L_t=28.21(1-e xp(-0.3169(t+0.8284)))$, and for sexes combined, $L_t=29.00(1-e xp(-0.3228(t+0.7361)))$, Seasonal growth equations derived from the mean observed fork length (cm) at age by month were as follows: for females, $L_t=29.2(1-e xp(-0.3458(t+0.8182)+(0.3458/2\pi)sin2\pi(t+0.027)))$, and for males, $L_t=28.2(1-e xp(-0.2789(t+1.5913)+(0.2789/2\pi)sin2\pi(t-0.1062)))$.

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