• Archives of Plastic Surgery
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• 제40권2호
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• pp.91-96
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• 2013

Background A thinned anterolateral thigh (ALT) flap is often harvested to achieve optimal skin resurfacing. Several techniques have been described to thin an ALT flap including an adipocutaneous flap, an adipofascial flap and delayed debulking. Methods By systematically reviewing all of the available literature in English and French, the present manuscript attempts to identify the common surgical indications, complications and donor site morbidity of the adipofascial variant of the ALT flap. The studies were identified by performing a systematic search on Medline, Ovid, EMBASE, the Cochrane Database of Systematic Reviews, Current Contents, PubMed, Google, and Google Scholar. Results The study selection process was adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and 15 articles were identified using the study inclusion criteria. These articles were then reviewed for author name(s), year of publication, flap dimensions and thickness following defatting, perforator type, type of transfer, complications, thinning technique, number of cases with a particular area of application and donor site morbidity. Conclusions The adipofascial variant of the ALT flap provides tissue to fill large defects and improve pliability. Its strong and safe blood supply permits adequate immediate or delayed debulking without vascular complications. The presence of the deep fascia makes it possible to prevent sagging by suspending and fixing the flap for functional reconstructive purposes (e.g., the intraoral cavity). Donor site morbidity is minimal, and thigh deformities can be reduced through immediate direct closure or liposuction and direct closure. A safe blood supply was confirmed by the rate of secondary flap debulking.

• 한국화재소방학회논문지
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• 제15권1호
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• pp.47-54
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• 2001

90년대 후반기부터 연이어 발생한 씨랜드 화재사고와 인천 인현동 라이브클럽 화재등의 동일한 유형을 가진 화재사건을 계기로 국내 다중이용업소의 실내장식재 및 장식물품에 사용하는 재료가 화재시 인명참사에 미치는 영향이 크다는 점이 발견되었다. 따라서 국내다중이용업소를 중심으로 실내장식재 및 장식물품의 사용과 관련한 화재안전규정 및 기준을 조사한 후에 유럽·미국 등의 선진국의 관련 규정을 조사 비교하여 그 문제점을 세부적으로 발췌하여 규제방향 및 규제기준의 상이점을 분석하여 대형인명참사를 초래하는 근본적인 원인을 찾아내었다. 고찰된 원인을 근간으로 실내장식재 및 장식물품에 사용하는 재료가 선진국 수준의 방재성능을 가질수 있도록 규제방향을 제시하고 제시된 규제방향을 뒷받침할 수 있는 효과적이고 검증된 시험방법을 연구제시하였다. 최종적으로 향후 발생가능한 대형인명참사를 효과적으로 방지하기 위해 다중이용업소를 중심으로 방화 및 방염제도의 효과적인 수립디 되도록 실내장식재 및 장식물품에 대한 세부규제안을 기술하여 방화 및 방염제도의 세부규안을 제시하였다.

• PNF and Movement
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• 제15권2호
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• pp.125-132
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• 2017

Purpose: This study reviewed articles to identify the optimal rhythmic stabilization or stabilizing reversals application method for improving balance. Methods: The Cochrane, EBSCO, eArticle, Embase, DBpia, KISS, Medline, ProQuest, PubMed, SAGE, ScienceDirect, Scopus, Springer, and Wiley databases were used to search articles from 1990 to January 2017. The search terms included: "rhythmic stabilization" and "stabilizing reversals." Only experimental human studies (randomized controlled trials) that compared the effects of varying the optimal application of rhythmic stabilization or stabilizing reversals to improve balance were included in the review. Non-English language (except Korean) and unpublished studies were excluded. Results: During the research, 1,098 articles were initially identified. Of these articles, nine were randomized controlled trials. Of these nine articles, five were in English, and four were in Korean. In addition, three of the trials did not measure the patients' balance, two did not report the intensity and location of the resistance, and three performed the rhythmic stabilization incorrectly. Only one article met the inclusion and exclusion criteria. The remaining study evaluated the participants' performance of the alternating trunk flexor and extensor isometric contraction of the scapulae using the optimal resistance for 10 seconds in a sitting position. The participants completed three sets of eight repetitions with rest intervals of 30 seconds between the repetitions and 60 seconds between the sets. Conclusion: Due to the lack of the scientific research on the topic, this review may not provide the evidence needed to support the optimal application of rhythmic stabilization or stabilizing reversals to improve balance. Future research should consider the methodological quality to identify the proper rhythmic standardization and stabilizing reversals application method.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.897-902
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• 2015

PTEN (phosphatase and tensin homologue), as a tumor suppressor gene, plays a significant role in regulating cell growth, proliferation, and apoptosis. Results from published studies for association between the PTEN IVS4 I/D (rs3830675) polymorphism and cancer risk are inconsistent and inconclusive. We therefore conducted a meta-analysis to evaluate the potential association between PTEN IVS4 I/D polymorphism and risk of cancer in detail. We searched PubMed (Medline) and EMBASE web databases to cover all relevant studies published until December 2013. The meta-analysis was carried out and pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) were used to appraise the strength of association. A total of 1,993 confirmed cancer cases and 3,200 controls were included from six eligible case-control studies. Results from overall pooled analysis suggested a significant effect of the PTEN IVS4 I/D polymorphism and cancer risk in all genetic models, i.e., allele (I vs D: OR=0.743, 95%CI=0.648 to 0.852, p=0.001), homozygous (II vs DD: OR=0.673, 95%CI=0.555 to 0.816, p=0.001), heterozygous (ID vs DD: OR=0.641, 95%CI=0.489 to 0.840, p=0.001), dominant (II+ID vs DD: OR=0.626, 95%CI=0.489 to 0.802, p=0.001) and recessive (II vs DD+ID: OR=0.749, 95%CI=0.631 to 0.889, p=0.001). Significant publication bias was detected during the analysis. The present meta-analysis suggests that the PTEN IVS4 I/D polymorphism is significantly associated with reduced risk of cancer. However, future larger studies with other groups of populations are warranted to clarify this association.

• 한국대기환경학회지
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• 제22권6호
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• pp.767-778
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• 2006

This study was carried out to evaluate the temporal variations of VOCs at an urban site, and to compare the concentrations of VOCs at an urban site in Daegu with those at a suburban site in Gyeongsan. Three hourly VOC samples in the ambient air were collected using a sequential tube sampler (STS 25, Perkin Elmer) throughout two weeks during May and July representing spring and summer seasons, respectively. The VOC concentrations were determined by an automatic thermal desorption apparatus with GC/MS analysis. A total of 12 VOCs of environmental concern were determined, which are chloroform, benzene, trichloroethylene, toluene, tetra-chloroethylene, ethylbenzene, m+p-xylenes, o-xylene, styrene, 1,3,5- and 1,2,4-trimethylbenzenes. Among 12 target VOCs, the most abundant compound appeared to be toluene, being followed by xylenes. The mean concentrations at the urbn site were 1.2 pub for benzene and 20.4 ppb for toluene (n=221) while the mean levels at the suburban site were 0.9 ppb and 4.3 ppb for benzene and toluene (n=96), respectively. The urban site concentrations were typically several-fold higher than those measured at the suburban site. It was found that general trends of VOC levels were significantly dependent on traffic conditions at the sampling site since VOC concentrations were at their maximum during rush hours, i.e. $9{\sim}12a.m$ and $6{\sim}9p.m$. Statistical investigations were conducted to investigate any significant relationships between VOC concentrations and affecting factors. Calculated correlation coefficients among VOCs were positively significant at a level of 0.05 in most cases. Increased concentrations of toluene in the urban site were estimated to reflect the effect of large industrial sources, mainly from textile industry.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권4호
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• pp.220-227
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• 2020

Objectives: Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder. These patients lose their teeth at a young age and are in need of prosthetic rehabilitation. The aim of this systematic review was to assess the success of dental implant placement in these patients. Materials and Methods: An electronic search was performed in PubMed Central, Scopus, and Web of Science using the keyword "Papillon-Lefèvre syndrome" AND "dental implant" OR "prosthodontics". Articles reporting implant placement in patients with PLS until July 2019 were included. Results: Assessment of the included 11 articles reporting 15 cases showed 136 implant placements in these patients. Implant failure occurred in 3 patients (20 implants). The peri-implantitis and failure rate was higher in the maxilla. Meta-analysis showed the probability of failure to be 7% (95% confidence interval [CI] 0%-31%) for maxillary implants and 2% (95% CI 0%-9%) for mandibular implants. The follow-up time ranged between 1 and 20 years. Healing after bone graft and implant placement in these patients was uneventful. Conclusion: Dental implants may be a viable treatment option for PLS patients. Implantation can help preserve alveolar bone if the patients' immunological and growing conditions are well-considered and proper oral hygiene and compliance with the maintenance program are continued.

• Clinical and Experimental Reproductive Medicine
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• 제43권4호
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• pp.233-239
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• 2016

Objective: Uterine contraction induced by the embryo transfer (ET) process has an adverse effect on embryo implantation. The aim of this study was to determine the effect of oxytocin antagonist supplementation on the day of ET on in vitro fertilization outcomes via a meta-analysis. Methods: We performed a meta-analysis of randomized controlled trials (RCTs). Four online databases (Embase, Medline, PubMed, and Cochrane Library) were searched through May 2015 for RCTs that investigated oxytocin antagonist supplementation on the day of ET. Studies were selected according to predefined inclusion criteria and meta-analyzed using RevMan 5.3. Only RCTs were included in this study. The main outcome measures were the clinical pregnancy rate, the implantation rate, and the miscarriage rate. Results: A total of 123 studies were reviewed and assessed for eligibility. Three RCTs, which included 1,020 patients, met the selection criteria. The implantation rate was significantly better in patients who underwent oxytocin antagonist infusion (19.8%) than in the control group (11.3%) (n = 681; odds ratio [OR], 1.92; 95% confidence interval [CI], 1.25-2.96). No significant difference was found between the two groups in the clinical pregnancy rate (n = 1,020; OR, 1.57; 95% CI, 0.92-2.67) or the miscarriage rate (n = 456; OR, 0.76; 95% CI, 0.44-1.33). Conclusion: The results of this meta-analysis of the currently available literature suggest that the administration of an oxytocin antagonist on the day of ET improves the implantation rate but not the clinical pregnancy rate or miscarriage rate. Additional, large-scale, prospective, randomized studies are necessary to confirm these findings.

• 한국대기환경학회지
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• 제22권3호
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• pp.325-336
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• 2006

The presence of volatile organic compounds (VOC), produced and released from both anthropogenic and natural sources, can accelerate the degradation of air quality in the surrounding area. In this study, we investigated the emission concentrations of VOC based on a total of 115 sample analysis made from 47 companies (representing 17 types of industry) at the Ban Wall industrial complex (Jun. 2004 to Jan. 2005). Through a statistical analysis of these measurement data, we inspected the emission characteristics of VOC in relation with industrial type and processing unit. When these data were compared each other, toluene was found to record the highest value of 423 ppb followed by ethylbenzene (68.3 ppb), m, p-xylene (43.6 ppb), o-xylene (27.2 ppb), styrene (23.9 ppb), and benzene (16.4 pub). In addition, by converting these VOC concentration data into malodor intensity, we attempted to account for their distribution patterns in terms of relative contribution to the malodor formation. The results of odor intensity conversion generally indicated that the odor intensities of individual VOC do not exceed the degree of 1. When our VOC results were compared against other odorous compounds measured concurrently, the results were highly contrasting each other. Despite relative insignificance as odorous compounds, these VOCs are generally found ubiquitously and in abundant quantities in this strong source area.

• The Journal of Advanced Prosthodontics
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• 제4권4호
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• pp.210-217
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• 2012

PURPOSE. The purpose of this study was to analyze the current literatures and to assess outcomes of implant treatment in patients with generalized aggressive periodontitis. MATERIALS AND METHODS. Studies considered for inclusion were searched in Pub-Med. The literature search for studies published in English between 2000 and 2012 was performed. Our findings included literature assessing implant treatment in patients with a history of generalized aggressive periodontitis (GAP). All studies were screened according to inclusion criteria. The outcome measures were survival rate of superstructures, marginal bone loss around implant and survival rate of implants. All studies were divided into two follow-up period: short term study (< 5 years) and long term study (${\geq}5$ years). RESULTS. Seven prospective studies were selected, including four short-term and three long-term studies. The survival rates of the superstructures were generally high in patients with GAP, i.e. 95.9-100%. Marginal bone loss around implant in patients with GAP as compared with implants in patients with chronic periodontitis or periodontally healthy patients was not significantly greater in short term studies but was significantly greater in long term studies. In short term studies, the survival rates of implants were between 97.4% and 100% in patients with GAP-associated tooth loss, except one study. The survival rates of implants were between 83.3% and 96% in patients with GAP in long term studies. CONCLUSION. Implant treatment in patients with GAP is not contraindicated provided that adequate infection control and an individualized maintenance program are assured.

• 구강회복응용과학지
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• 제31권2호
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• pp.112-125
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• 2015

구강 내의 모습을 재현하는 복제모델을 만드는 것은 치과 진료에서 가장 중요한 과정이며 정확성과 효율성이 동시에 만족되어야 하는 과정이다. 현재 기술이 발전함에 따라 치과 진료에서도 디지털화가 이루어지고 있다. 이러한 것을 가능하게 하는 가장 중요한 작업 중 하나가 바로 구강 내의 모습을 3차원적으로 재구성하는 디지털화이다. CAD/CAM 시스템의 3가지 성분 (1) data capture component (digitizers), (2) design component (CAD software), (3) manufacturing component (CAM)중 가장 기본이 되며 뒤의 과정에 막대한 영향을 끼치는 것이 data capture component 즉 구강 스캐너이다. 이 논문은 Pubmed와 Google Scholar에서 최근 5년 전 연구 논문들을 기초로 하여, 각각의 스캐너의 구동원리와 스캐너들 간의 정확성, 현재 구강 스캐너가 치과 영역에서 적용되고 있는 분야와 그 정도를 분석하였다.