• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.389-392
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• 2015

We identify a strong lensing galaxy in the cluster IRC 0218 that is spectroscopically confirmed to be at z = 1.62, making it the highest-redshift strong lens galaxy known. The lens is one of the two brightest cluster galaxies and lenses a background source galaxy into an arc and a counterimage. With Hubble Space Telescope (HST) grism and Keck/LRIS spectroscopy, we measure the source redshift to be $z_S=2.26$. Using HST imaging, we model the lens mass distribution with an elliptical power-law profile and account for the effects of the cluster halo and nearby galaxies. The Einstein radius is $^{\theta}E=0.38^{+0.02{\prime}{\prime}}_{-0.01}$ ($3.2^{+0.2}_{-0.1}kpc$) and the total enclosed mass is $M_{tot}(<^{\theta}_E)=1.8^{+0.2}_{-0.1}{\times}10^{11}M_{\odot}$. We estimate that the cluster environment contributes ~ 10% of this total mass. Assuming a Chabrier IMF, the dark matter fraction within $^{\theta}E$ is $f^{Chab}_{DM}=0.3^{+0.1}_{-0.3}$, while a Salpeter IMF is marginally inconsistent with the enclosed mass ($f^{Salp}_{DM}=-0.3^{+0.2}_{-0.5}$).

• Journal of Software Assessment and Valuation
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• v.16 no.2
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• pp.77-85
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• 2020

In this paper, We studied the operation of distributed ledger technology used as a core technology for smart contracts and the components of distributed ledger technology. As a solution applying the entity of distributed ledger technology to NoE, we proposed the protocol of the distributed ledger technology using the thing user social group management function of NoE protocols being standardized in ISO/IEC JTC1 SC6. The management function of things user social group in NoE provides stable protocol functions and data transmission management, and provides group management functions such as member discovery function and data transmission channel management function. It is expected to be useful for member management functions of distributed ledger nodes by providing a service that apply the component of distributed ledger technology. We intend to actively reflect this technology in the future network functions of ISO/IEC JTC1 SC6, which is undergoing standardization.

• Genomics & Informatics
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• v.21 no.2
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• pp.17.1-17.12
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• 2023

Coronavirus has left severe health impacts on the human population, globally. Still a significant number of cases are reported daily as no specific medications are available for its effective treatment. The presence of the CD147 receptor (human basigin) on the host cell facilitates the severe acute respiratory disease coronavirus 2 (SARS-CoV-2) infection. Therefore, the drugs that efficiently alter the formation of CD147 and spike protein complex could be the right drug candidate to inhibit the replication of SARS-CoV-2. Hence, an e-Pharmacophore model was developed based on the receptor-ligand cavity of CD147 protein which was further mapped against pre-existing drugs of coronavirus disease treatment. A total of seven drugs were found to be suited as pharmacophores out of 11 drugs screened which was further docked with CD147 protein using CDOCKER of Biovia discovery studio. The active site sphere of the prepared protein was 101.44, 87.84, and 97.17 along with the radius being 15.33 and the root-mean-square deviation value obtained was 0.73 Å. The protein minimization energy was calculated to be -30,328.81547 kcal/mol. The docking results showed ritonavir as the best fit as it demonstrated a higher CDOCKER energy (-57.30) with correspond to CDOCKER interaction energy (-53.38). However, authors further suggest in vitro studies to understand the potential activity of the ritonavir.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.68 no.3
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• pp.175-187
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• 2023

Peanuts, also known as groundnuts (Arachis hypogaea L.), are globally recognized as a vital oilseed crop. Peanuts are rich in proteins (e.g., arginine), oils (e.g., oleic acid and linoleic acid), fiber, vitamins (e.g., niacin and tocopherol), and carbohydrates and are consumed worldwide. However, the presence of aflatoxin (AF) has garnered substantial attention since its initial discovery as the causative agent of Tukey's X disease in the United Kingdom in 1960. Among the 18 aflatoxins identified, aflatoxin B₁ (AFB₁) has the highest toxic activity and causes hepatocellular carcinoma. It is classified as Group I by the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO). The present study was conducted to evaluate aflatoxin B₁ resistance of 102 peanut accessions and select putative aflatoxin B₁-resistant peanut accessions to aflatoxin B₁. One hundred and one Korean germplasms harvested in 2020 were inoculated with A. flavus to identify aflatoxin-resistant cultivars, and the aflatoxin B₁ concentration was measured using an ultra-performance liquid chromatography-photodiode array detector. Twenty-six accessions with aflatoxin B₁ concentrations lower than those of the check plant 55-437 were chosen for the development of aflatoxin-resistant varieties in Korea. As Korean aflatoxin-resistant varieties have not yet been developed, the findings of the present study are expected to provide useful information for the development of aflatoxin-resistant cultivars.

• Journal of radiological science and technology
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• v.47 no.1
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• pp.21-28
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• 2024

This study was purpose to quantitative evaluation of comparison of the image intensity uniformity and noise power spectrum (NPS) by using American college of radiology (ACR) phantom for magnetic resonance imaging (MRI). The MRI was used achiva 3.0T MRI and discovery MR 750, 3.0T, the head and neck matrix shim SENSE head coil were 32 channels receive MR coil. The MRI was used parameters of image sequence for ACR standard and general hospital. NPS value of the ACR standard T2 vertical image in GE equipment was 7.65E-06 when the frequency was 1.0 mm^-1. And the NPS value of the ACR hospital T1 region of interest (ROI) 9 over all vertical image in Philips equipment was 9E-08 when the frequency was 1.0 mm^-1 and the NPS value of the hospital T2 ROI 9 over all vertical image in Philips equipment was 1.06E-07 when the frequency was 1.0 mm^-1. NPS was used efficiently by using a general hospital vertical sequence more than the standard vertical sequence method by using the ACR phantom. Furthermore NPS was the quantitative quality assurance (QA) assessment method for noise and image intensity uniformity characteristics was applied mutatis mutandis, and the results values of the physical imaging NPS of the 3.0T MRI and ACR phantom were presented.

• Journal of Korea Multimedia Society
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• v.7 no.8
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• pp.1131-1144
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• 2004

In this paper, we investigate a problem with an e-learning system for e-business environments and introduce the solving method of the problem. To be more accurate, existing Web-hosted and ASP (Application Service Provider)-oriented service model is difficult to cooperate and integrate among the different kinds of systems. So we have produced sharable and reusable learning object, they have extracted a principle from pedagogical designs for units of reuse. We call LIO (Learning Item Object). This modeling makes use of a constructing for XML Web Services. So to speak, units of reuse from pedagogical designs are test tutorial, resource, case example, simulation, problem, test, discovery and discussion and then map introduction, fact, try, quiz, test, link-more, tell-more LIO learning object. These typed LIOs are stored in metadata along with the information for a content location. Each one of LIOs is designed with components and exposed in an interface for XML Web services. These services are module applications, which are used a standard SOAP (Simple Object Access Protocol) and locate any computer over Internet and publish, find and bind to services. This guarantees the interoperation and integration of the different kinds of systems. As a result, the problem of e-learning systems for e-business environments was resolved and then the power of understanding about learning objects based on pedagogical design was increased for learner and instruction designers. And organizations of education hope for particular decreased costs in constructing e-learning systems.

• Journal of Intelligence and Information Systems
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• v.22 no.4
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• pp.87-107
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• 2016

Understanding market convergence has became essential for small and mid-size enterprises. Identifying convergence items among heterogeneous markets could lead to product innovation and successful market introduction. Previous researches have two limitations. First, traditional researches focusing on patent databases are suitable for detecting technology convergence, however, they have failed to recognize market demands. Second, most researches concentrate on identifying the relationship between existing products or technology. This study presents a platform to identify the opportunity of market convergence by using product databases from a global B2B marketplace. We also attempt to identify convergence opportunity in different industries by applying Structural Hole theory. This paper shows the mechanisms for market convergence: attributes extraction of products and services using text mining and association analysis among attributes, and network analysis based on structural hole. In order to discover market demand, we analyzed 240,002 e-catalog from January 2013 to July 2016.

• ETRI Journal
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• v.35 no.1
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• pp.7-17
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• 2013

The ongoing proliferation of new services, applications, and contents is leading the Internet to an architectural crisis owing to its inability to provide efficient solutions to new requirements. Clean-slate architectures for the future Internet offer a new approach to tackle current and future challenges. This proposal introduces a novel clean-slate architecture in which the TCP/IP protocol stack is decoupled in basic functionalities, that is, atomic services (ASs). A negotiation protocol, which enables context-aware service discovery for providing adapted communications, is also specified. Then, we present how ASs can be discovered and composed according to requesters' requirements. In addition, a media service provisioning use case shows the benefits of our framework. Finally, a proof-of-concept implementation of the framework is described and analyzed. This paper describes the first clean-slate architecture aligned with the work done within the ISO/IEC Future Network working group.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.41-44
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• 2005

Cytokines play a crucial role in the immune and inflammatory responses. But because of the high evolutionary rate of these proteins, the similarity between different members of their family is very low, which makes the identification of novel members of cytokines very difficult. According to this point, a new bioinformatic strategy to identify novel cytokine of the short-chain and long-chain 4${\alpha}$ helix cytokine using hidden markov model (HMM) is proposed in the paper. As a result, two motifs were created on the two train data sets, which were used to search three different databases. In order to improve the result, a strict criterion is established to filter the novel cytokines in the subject proteins. Finally, according to their E-value, scores and the criterion, four subject proteins are predicted to be possible novel cytokines for each family respectively.

• Journal of Dairy Science and Biotechnology
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• v.37 no.3
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• pp.155-166
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• 2019

Bacteria from the genus Lactobacillus are important for the production of fermented food and dairy products, and as symbionts in human and animals. Lactobacillus acidophilus has widely been used in the production of yogurt, health foods, and even medicines. The efficacy of L. acidophilus has been proven with regards to the reduction of cholesterol, prevention and treatment of diarrhea, modulation of the immune system, suppression of cancer, etc. Using molecular biology tools, Lactobacillus acidophilus has now been reclassified into six species: L. acidophilus, L. amylovorus, L. crispatus, L gallinarium, L. gasseri, and L. johnsonii. Thus, since L. acidophilus has now been marked as a newly defined species, caution is advised when reading future publications regarding this bacterium. In this article, the results of the reclassification of L. acidophilus are mentioned after an analysis of its field inheritance was performed by my research team. Especially, L. amylovorus KU4 (formerly named as L. acidophilus KU4; KCCM 10975P) is a novel probiotic strain that is isolated from humans; it has the ability to reduce cholesterol. It has also been reported as a microorganism that effectively inhibits the growth of pathogenic E. coli. However, this Korean patent (No 10-1541280) refers to a strain obtained from calves; the origin of this strain was incorrectly labeled. Furthermore, after the discovery of L. acidophilus in 1900, its role in intestinal microbiological research was described and its utilization as a probiotic was presented.