• Electrical & Electronic Materials
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• v.30 no.5
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• pp.3-8
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• 2017

• Journal of Pharmaceutical Investigation
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• v.23 no.3
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• pp.41-50
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• 1993

The iontophoretic delivery across rat skin of quaternary ammonium salts (isopropamide: ISP, pyridostigmine: PS), which are positively charged over a wide pH range, was measured ill vitro. The study showed that: (a) iontophoresis significantly enhanced delivery of ISP and PS compared to respective passive transport; (b) delivery of ISP and PS was directly proportional to the applied continuous direct current density over the range of $0-0.69\;mA/cm^2;$ (c) delivery of ISP and PS was also proportional to the drug concentration in the donor compartment over the range of $0-2{\time}l0^{-2}M:$ (d) sodium ion in the donor compartment inhibited the drug transport possibly due to decreasing the electric transference number of the drug; (e) delivery of ISP and PS increased as the pH of the donor solution increased over the pH range 2-7 suggesting permselective nature of the epidermis, and inhibition of the transference number of the drugs by hydronium ion; (f) some organic anions such as taurodeoxycholate, salicylate and benzoate which form lipophilic ion-pair complexes with ISP inhibited the delivery of ISP. The degree of inhibition by the organic anions was linearly proportional to the extraction coefficient $(K_e)$ of ISP from the partition system with each counteranion between phosphate buffer (pH 7.4) and n-octanol. For PS, however, taurodeoxycholate, but not salicylate and benzoate inhibited the iontophoretic delivery. It suggests that not only sodium ion and hydronium ion but also the counteranions which form lipophilic ion-pairs with quaternary ammonium drugs are not favorable components in formulating the donor solution of the drugs to achieve an effective iontophoretic delivery.

• Journal of Pharmaceutical Investigation
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• v.30 no.1
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• pp.1-12
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• 2000

Gene therapy is a method for the treatment of diseases with introducing the gene-engineered materials into a patient with gene-deficiency disease (e.g. cystic fibrosis) or cancer to produce a therapeutic protein in a patient's cells. Successful gene therapy requires establishing both gene expression systems and delivery systems. Viral and non-viral vectors have been used for gene delivery. Viral vectors have a high transfection efficiency, but are limited in relations to issues of safety, toxicity and immunogenecity. Non-viral vectors are easy to prepare and relatively safe. However, non-viral vectors have a low transfection efficiency. Cationic liposomes are the most available among non-viral vectors. Cationic liposomes have been used to transfect cells both in vitro and in vivo experiments. Besides, several formulations containing cationic lipid are being used in clinical trials in cases of cystic fibrosis or cancer. A crucial subject to the further development of gene delivery vectors will be a long-term gene expression with following characteristics; protecting and deliverying DNA efficiently, non-toxic and non-immunogenic, and easy to produce in large scale.

• IE interfaces
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• v.9 no.2
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• pp.159-171
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• 1996

In recent, most'of automobile industries adopt the concept of JIT production. According to the concept, the paternal manufacturers require their suppliers to supply parts just in time, so it is very important for a subcontractor to produce the parts in the appointed time of delivery. This study develops a production information system for Woosin Industry, which is one of such subcontractors of Hyundai Motors Company(HMC). The system is developed for use in Client/Server environment. In this study, the following three modules are developed, i. e., the production scheduling module, the sales management module to deal with the information about orders of HMC, delivery of parts, and bill collecting, and the module for supporting material requirements planning and purchase of material.

• International Commerce and Information Review
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• v.13 no.3
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• pp.169-201
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• 2011

There was a new wave in grocery business with development of information and technology, thus a movement from traditional stores to online stores, In order to expand the scale of traditional supermarket and to satisfy the customers' needs, they provide offline and online services simultaneously. This paper is based on the previous studies which had been researched in developed countries from late 1990s to early 2000s and the purpose of this study is to introduce the idea and operation system of e-Grocery business. Moreover, we suggest the alternatives on delivery service methods in order to satisfy the customers' needs through analyzing the current condition of e-Grocers in Korea. According to the result of this study, Korean e-Grocers offer only attended home delivery services. In our opinion, Korean supermarkets have to take hybrid model which Tesco.com is using. There are some alternatives to increase the profits of Korean e-Grocers and to provide better services to their customers as follows: As an alternatives for delivery services, picking service is the easiest and cheapest way to apply for supermarkets. This is very useful for working women and also it is possible to order by smartphone recently. They can order the goods to the closest local supermarkets from working place, and then they pick them up on the way home from working off. In order to improve the quality of delivery services, to use the reception box will be the way to provide better services to the customers. The reception box is a way to protect the quality of goods such as fresh-cut product, which require the freshness through the temperature adjustment, and also to keep the safety of ordered goods through locking system Through this system, supermarkets are able to use attended or unattended services under the customers' satisfaction. However, using the reception box is expensive, so shared reception box will be an alternative. As an alternative for development of e-Grocery business, the advertisement for e-Grocery business has to be supported in order to attract potential customers in e-Grocery business. Furthermore, the main concerns of e-Grocery business such as the sanitation and safety of goods, and convenience must be guaranteed in order to keep the loyal customers and to attract new customers.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2012.11a
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• pp.233-235
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• 2012

Continually having growed up overseas construction market for new Nuclear Power Plant(NPP), the exports of Korean Reactor emerges as the key task of National Nuclear Business. The objective of this study is to strengthen the competitiveness of Korean Reactor through the improvement of Construction Project Contract & Delivery System for NPP. This study suggests the method for increasing Korean Reactor's competitiveness of exports by analyzing the business environment of foreign market and comparing Contract & Delivery System between domestic and foreign.

• Journal of KIISE:Computing Practices and Letters
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• v.9 no.6
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• pp.602-609
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• 2003

Emerging high-speed next-generation Internet is enabling immersive media communication systems and applications to realize geographically distributed team collaborations while overcoming the limit of distance and time. Focusing on the reliable real-time delivery of 3D (i.e., stereo) video among corresponding parties, in this paper, key schemes for stereo video processing/display and reliable transport of stereo video packets over high-speed Internet are designed and implemented. The performance of proposed stereo video delivery system is evaluated both by emulating various network situations for quantitative comparison and by transmitting over real-world Internet up to the speed of around 100 Mbps. The results demonstrate the feasibility of the proposed system in supporting the desired immersive communication.

• Journal of Korean Society for Quality Management
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• v.31 no.2
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• pp.98-116
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• 2003

The objective in this paper is to develope the e-Supply Chain Management System and applied for the Manufacturing. A Manufacturing that is consider to be world class recognize that its ability to complete in the marketplace depends on developing e-SCM System that is properly align with its mission of serving the customer. This paper investigated the relationship between e-SCM and performance in manufacturing. A stratified random sample was collected from the Federation of Korea Industries. Conclusively, e-SCM is important factor between source factors (environmental dynamic, Leadership) and manufacturing performance. e-SCM is significantly related to Quality, Flexibility, Delivery, and Cost.

• Journal of Families and Better Life
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• v.33 no.2
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• pp.53-70
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• 2015

The number of Healthy Family Support Centers has dramatically increased and the services for healthy families such as family education, family counsel, family culture and family care have increased during the past ten years since the Framework Act on Healthy Families was enacted. This growth is largely credited to Healthy Family Specialists. At a time when the family policy delivery system is changing, it is most urgent to enhance the capability of Healthy Family Specialists. In this study, we aim to investigate the current capability of Healthy Family Specialists and suggest the education plan for their empowerment. We collected data from 151 Healthy Family Support Centers by mail and e-mail in June 2014. There were total of 1,001 subjects for analysis(781 by mail and 220 by e-mail). We analyzed the capabilities of Healthy Family Specialist by service areas according to work-related characteristics and possession of a license. Our findings revealed that the capabilities of Healthy Family Specialist varied depending on the service year and whether or not having a licence. These results suggest that the education program for empowerment will provide a differentiated content according to the service year and whether or not having a license. This study contributes to a better understanding of Healthy Family Specialists' current capability and provides insights on how to enhance their capability in order to change the family policy delivery system.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.36 no.3
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• pp.133-141
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• 2013

The revitalization of e-business via Internet brings big changes to the postal business, and leads to a tremendous increase of heavy and large sized postal mails with continuing growth of home delivery business. Thus, even though the number of intermediate storages for mail delivery that mailmen use for picking up mails in the middle of mail delivery has been being increased, it has still many problems such as insufficient number and size of the storages as well as avoidance of mail keeping of trust agents. It is necessary that safety of mail keeping, seamless mail delivery, and individual parcel pick-up process reestablishment should be made through an improved counter plan for the problems described previously. This study presents the efficient and right operational plan for the intermediate storage for mail delivery with providing the number and size of intermediate storages per mail delivery sequence according to four different types of post offices.