• Title/Summary/Keyword: e-Ring

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Isolation of Acetylcholinesterase Inhibitors from the Flowers of Chrysanthemum indicum Linne

  • Lim, Soon-Sung;Han, Sag-Myung;Kim, Sun-Young;Bae, Young-Soo;Kang, Il-Jun
    • Food Science and Biotechnology
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    • v.16 no.2
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    • pp.265-269
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    • 2007
  • There is significant interest in finding new sources of acetylcholinesterase (AChE) inhibitors for use in treating Alzheimer's disease, since only a few AChE inhibitors are available for clinical use, such as galanthamine, physostigmine, and tacrine. The ethanol extract of Chrysanthemum indicum Linne flowers was analyzed and found to markedly decrease AChE activity. Acaciin and $acacetin-7-O-{\beta}-D-galactopyranoside$ were identified as the active compounds responsible for the AChE inhibition by using an activity-guided fractionation strategy. The relationship between structure and activity for five flavonoids (acaciin, $acacetin-7-O-{\beta}-D-galactopyranoside$, luteolin, and two other commercially available flavonoids, i.e., apigenin and acacetin) was also investigated, revealing that the presence of methoxy groups at C-4' in the B ring and a sugar at O-7 in ring A appear to be essential for the inhibition of AChE.

Synthesis of Dihydroxylated Chalcone Derivatives with Diverse Substitution Patterns and Their Radical Scavenging Ability toward DPPH Free Radicals

  • Kim, Beom-Tae;O, Kwang-Joong;Chun, Jae-Chul;Hwang, Ki-Jun
    • Bulletin of the Korean Chemical Society
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    • v.29 no.6
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    • pp.1125-1130
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    • 2008
  • A series of dihydroxylated chalcone derivatives with diverse substitution patterns on a phenyl ring B and the para-substituents on a phenyl ring A were prepared, and their radical scavenging activities were evaluated by simple DPPH test to determine quantitative structure-activity relationship in these series of compounds. The chalcone compounds with the ortho- (i.e. 2',3'- and 3',4'-) and para- (i.e. 2,5'-) substitution patterns show an excellent antioxidant activities (80-90% of control at the concentration of 50 $\mu$M) which are comparable to those of ascorbic acid and $\alpha$ -tocopherol as positive reference materials. On the contrary, the compounds with meta- (i.e. 2',4'-, 3',5'-) substitution pattern demonstrate very dramatic decrease in activities which are around 25% of the control even at the concentration of 200 $\mu$ M (IC50 > 200 $\mu$ M). These dramatic differences could be interpreted in terms of the ease formation of fairly stable semiquinone radicals from the ortho- and parasubstituted chalcone molecules through facilitating electron delocalization. Our results indicate that the substitution patterns of two hydroxyl groups on ring B are very important structural factors for their radical scavenging activity enhancement. Meanwhile, the substituents at para-position of the phenyl ring A of chalcones have no influence on the activity.

INJECTIVE COVERS OVER COMMUTATIVE NOETHERIAN RINGS OF GLOBAL DIMENSION AT MOST TWO II

  • KIM, HAE-SIK;SONG, YEONG-MOO
    • Communications of the Korean Mathematical Society
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    • v.20 no.3
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    • pp.437-442
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    • 2005
  • In studying injective covers, the modules C such that Hom(E, C) = 0 and $Ext^1$(E, C) = 0 for all injective module E play an important role because of Wakamatsu's lemma. If C is a module over the ring k[[x, y]] with k a field, the class of these modules C contains the class $\={D}$ of all direct summands of products of modules of finite length ([3, Theorem 2.9]). In this paper we show that every module over any commutative ring has a $\={D}$-preenvelope.

Ring-Opening Polymerization of Substituted 3,4-Dihydro-2H-pyrans. Syntheses of Alternating Vinyl Copolymers of Dimethyl Dicyanofumarate and Electron-Rich Olefins

  • Lee, Ju-Yeon;Cho, I-Whan
    • Bulletin of the Korean Chemical Society
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    • v.7 no.5
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    • pp.372-376
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    • 1986
  • Substituted 3,4-dihydro-2H-pyrans ($1_{a-e}$) were prepared by (4 + 2) cycloaddition reaction of dimethyl dicyanofumarate with the corresponding electron-rich olefins. The compounds $1_{a-e}$ were ring-open polymerized by cationic initiators to obtain polymers of 1:1 alternating sequence. Polymerizations were carried out with boron trifluoride etherate in methylene chloride at $-78^{\circ}C$. All the polymers obtained were soluble in common solvents and were reprecipitated by pouring its chloroform solution into diethyl ether. All the compounds $1_{a-e}$ were not as reactive as the corresponding pyrans derived from ${\alpha}$ -cyanoacrylate.

On a Transversality over Local Global Rings

  • Shin, Kee-Young
    • Journal of the Chungcheong Mathematical Society
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    • v.7 no.1
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    • pp.33-39
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    • 1994
  • The purpose of this paper prove the following property; Suppose A has many units (local global ring) and |A/m| > 5 for every maximal ideal $m{\subseteq}A$. Let(E, q) ${\in}$ Q(A) and $E=E_1{\bot}{\cdots}{\bot}E_t$ be an orthogonl decomposition of E with $t{\geq}2$ and $rk(E_i){\geq}1$, for $i=1,{\cdots},t$. Let $x{\in}E$ be a primitive vector. Then there exists ${\sigma}{\in}O(q)$ such that ${\sigma}(x)$ is transversal to this decomposition.

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Vibrational Relaxation and Bond Dissociation in Methylpyrazine on Collision with N2 and O2

  • Young-Jin Yu;Sang Kwon Lee;Jongbaik Ree
    • Journal of the Korean Chemical Society
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    • v.67 no.6
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    • pp.407-414
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    • 2023
  • The present study uses quasi-classical trajectory procedures to examine the vibrational relaxation and dissociation of the methyl and ring C-H bonds in excited methylpyrazine (MP) during collision with either N2 or O2. The energy-loss (-ΔE) of the excited MP is calculated as the total vibrational energy (ET) of MP is increased in the range of 5,000 to 40,000cm-1. The results indicate that the collision-induced vibrational relaxation of MP is not large, increasing gradually with increasing ET between 5,000 and 30,000 cm-1, but then decreasing with the further increase in ET. In both N2 and O2 collisions, the vibrational relaxation of MP occurs mainly via the vibration-to-translation (V→T) and vibration-to-vibration (V→V) energy transfer pathways, while the vibration-to-rotation (V→R) energy transfer pathway is negligible. In both collision systems, the V→T transfer shows a similar pattern and amount of energy loss in the ET range of 5,000 to 40,000cm-1, whereas the pattern and amount of energy transfer via the V→V pathway differs significantly between two collision systems. The collision-induced dissociation of the C-Hmethyl or C-Hring bond occurs when highly excited MP (65,000-72,000 cm-1) interacts with the ground-state N2 or O2. Here, the dissociation probability is low (10-4-10-1), but increases exponentially with increasing vibrational excitation. This can be interpreted as the intermolecular interaction below ET = 71,000 cm-1. By contrast, the bond dissociation above ET = 71,000 cm-1 is due to the intramolecular energy flow between the excited C-H bonds. The probability of C-Hmethyl dissociation is higher than that of C-Hring dissociation.

ON SUBDIRECT PRODUCT OF PRIME MODULES

  • Dehghani, Najmeh;Vedadi, Mohammad Reza
    • Communications of the Korean Mathematical Society
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    • v.32 no.2
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    • pp.277-285
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    • 2017
  • In the various module generalizations of the concepts of prime (semiprime) for a ring, the question "when are semiprime modules subdirect product of primes?" is a serious question in this context and it is considered by earlier authors in the literature. We continue study on the above question by showing that: If R is Morita equivalent to a right pre-duo ring (e.g., if R is commutative) then weakly compressible R-modules are precisely subdirect products of prime R-modules if and only if dim(R) = 0 and R/N(R) is a semi-Artinian ring if and only if every classical semiprime module is semiprime. In this case, the class of weakly compressible R-modules is an enveloping for Mod-R. Some related conditions are also investigated.

A UWB design of an Annular Ring Patch Antenna (환고리형 패치 안테나의 초광대역 설계)

  • Choi Won-Kyu;Hwang Hee-Yong;Choi Kyung;Choi Se-Ha
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.2 no.4
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    • pp.28-41
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    • 2003
  • A micros-strip ring patch antenna with ultra wide band characteristics is presented. The proposed antenna is designed by a modified form of the annular ring patch antenna with modified microstrip feedline. The designed antenna gives 5.6GHz bandwidth with regular radiation pattern from 4.4GHz to 12.0GHz for -10dE return loss or VSWR of less than 2.0 in simulation, which is also excellently agreed with the measured data.

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Tree-Ring Dating of Wood Elements Used for the Jeongjagak and Bigak Buildings of Kangrung (King Myoungjong's Tomb) (강릉 (명종) 정자각과 비각 목부재의 연륜연대 분석)

  • Lee, Kwang-Hee;Kim, Sang-Kyu;Park, Won-Kyu
    • Journal of the Korea Furniture Society
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    • v.19 no.3
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    • pp.219-228
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    • 2008
  • Kangrung is a royal tomb for King Myoungjong and his wife, Queen Jeongsun. According the record, Myoungjong died on 1567 and was buried in the present location at Gongrungdong, Nowonku, Seoul. During the 2006 repair for the Jeongjagak (memorial hall) and Bigak (tombs' house) of Kangrung, a dendrochronological analysis had been conducted. We took 79 samples, 74 from Jeongjagak and 5 from Bigak, respectively, for dating. There were three major cutting groups, i.e., 1692-1694, 1737, and 1859-1861. The first group was well matched with the date of reconstruction, which was written on the 'Sangryangmun', a formal record about building activities. The tree-ring results confirmed that the present buildings of Jeongjagak and Bigak in Kangrung were reconstructed in 1695. The second and third cutting groups indicated major repairs in Bigak.

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ON (α, δ)-SKEW ARMENDARIZ RINGS

  • MOUSSAVI A.;HASHEMI E.
    • Journal of the Korean Mathematical Society
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    • v.42 no.2
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    • pp.353-363
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    • 2005
  • For a ring endomorphism $\alpha$ and an $\alpha$-derivation $\delta$, we introduce ($\alpha$, $\delta$)-skew Armendariz rings which are a generalization of $\alpha$-rigid rings and Armendariz rings, and investigate their properties. A semi prime left Goldie ring is $\alpha$-weak Armendariz if and only if it is $\alpha$-rigid. Moreover, we study on the relationship between the Baerness and p.p. property of a ring R and these of the skew polynomial ring R[x; $\alpha$, $\delta$] in case R is ($\alpha$, $\delta$)-skew Armendariz. As a consequence we obtain a generalization of [11], [14] and [16].