• 한국전자거래학회지
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• 제4권2호
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• pp.177-196
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• 1999

The current process of weapon system R&D has lots of problems that the phase is complex, the concept of integration and/or connection of related data is laked and don't be digitalized. To solve these problems we should establish the R&D CALS system and to do this, analysis the R&D process is necessary. In this paper, We suggested weapon system R&D CALS concept and model, and analysed R&D process with ARIS Toolset and proposed the new R＆D process and operation scenarios with CALS concept.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제11권2호
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• pp.9-14
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• 2007

A signed 3-partite graph is a 3-partite graph in which each edge is assigned a positive or a negative sign. Let G(U, V, W) be a signed 3-partite graph with $U\;=\;\{u_1,\;u_2,\;{\cdots},\;u_p\},\;V\;=\;\{v_1,\;v_2,\;{\cdots},\;v_q\}\;and\;W\;=\;\{w_1,\;w_2,\;{\cdots},\;w_r\}$. Then, signed degree of $u_i(v_j\;and\;w_k)$ is $sdeg(u_i)\;=\;d_i\;=\;d^+_i\;-\;d^-_i,\;1\;{\leq}\;i\;{\leq}\;p\;(sdeg(v_j)\;=\;e_j\;=\;e^+_j\;-\;e^-_j,\;1\;{\leq}\;j\;{\leq}q$ and $sdeg(w_k)\;=\;f_k\;=\;f^+_k\;-\;f^-_k,\;1\;{\leq}\;k\;{\leq}\;r)$ where $d^+_i(e^+_j\;and\;f^+_k)$ is the number of positive edges incident with $u_i(v_j\;and\;w_k)$ and $d^-_i(e^-_j\;and\;f^-_k)$ is the number of negative edges incident with $u_i(v_j\;and\;w_k)$. The sequences ${\alpha}\;=\;[d_1,\;d_2,\;{\cdots},\;d_p],\;{\beta}\;=\;[e_1,\;e_2,\;{\cdots},\;e_q]$ and ${\gamma}\;=\;[f_1,\;f_2,\;{\cdots},\;f_r]$ are called the signed degree sequences of G(U, V, W). In this paper, we characterize the signed degree sequences of signed 3-partite graphs.

• 대한수학회논문집
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• 제22권1호
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• pp.65-74
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• 2007

Suppose that $\mu$ is a finite positive Borel measure on bounded symmetric domain $\Omega{\subset}\mathbb{C}^n\;and\;\nu$ is the Euclidean volume measure such that $\nu(\Omega)=1$. Suppose 1 < p < $\infty$ and r > 0. In this paper, we will show that the norms $sup\{\int_\Omega{\mid}k_z(w)\mid^2d\mu(w)\;:\;z\in\Omega\}$, $sup\{\int_\Omega{\mid}h(w)\mid^pd\mu(w)/\int_\Omega{\mid}h(w)^pd\nu(w)\;:\;h{\in}L_a^p(\Omega,d\nu),\;h\neq0\}$ and $$sup\{\frac{\mu(E(z,r))}{\nu(E(z,r))}\;:\;z\in\Omega\}$$ are are all equivalent. We will also show that the inclusion mapping $ip\;:\;L_a^p(\Omega,d\nu){\rightarrow}L^p(\Omega,d\mu)$ is compact if and only if lim $w\rightarrow\partial\Omega\frac{\mu(E(w,r))}{\nu(E(w,r))}=0$.

• 시스템엔지니어링학술지
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• 제5권1호
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• pp.7-20
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• 2009

This paper describes a case study on the R&D programs of fighter and attacker aircraft such as F-22A, F/A-18E/F, and T/A-50. F-22A and F/A-18E/F were developed in same age. The performance of each program was, however extremely different. F-22A program results in a lot of cost overrun and schedule delay. On the other hand F/A-18E/F program met the cost, schedule, and performance goals. In the T/A-50 program with a super-sonic advanced trainer, T-50 was also developed successfully on planned cost and time by Korea Air-force and KAI. This paper derives key elements for the success of the military aircraft R&D program through lessons learned from th e case study. Each program is analyzed in terms of its background, planning and management.

• 한국IT서비스학회:학술대회논문집
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• 한국IT서비스학회 2002년도 추계학술대회
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• pp.304-310
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• 2002

인터넷 기반의 B2B(Business to Business) 모델은 e비즈니스의 실현을 위한 기업의 정보시스템의 인프라와 같은 기반구조를 만들어가기 위한 기본 모델 역할을 하고 있다. 인터넷이 제공하는 표준 프로토콜을 기반으로 다양한 방식의 B2B 지원제품이 출시되고 있지만 그 어떤 제품도 기본적인 인터넷 프로토콜이 아닌 상위의 e비즈니스, 즉 다른 기업과의 협업이라는 관점에서 상호운용성을 보장하지 못하고 있으며 이 부분은 여전히 제품과 산업군에 매우 종속적이다. 이러한 단점을 해결하기 위하여 국제표준을 준수하며 BRB(Business- Registry- Business) 모델을 기반으로 한 글로벌 e비즈니스 솔루션인 XENI의 메세징 관련 제품과 레지스트리 관련 제품의 구현사례와 활용사례를 소개하고자 한다. 또한 국내의 취약한 SI 산업의 해결점이 될 수 있는 글로벌 솔루션 개발이라는 측면에서 향후 보완되어야 할 부분들을 제안한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3961-3968
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• 2015

Background: Variants of human papillomavirus (HPV) show more oncogenicity than do prototypes. The HPV16 Asian variant (HPV16As) plays a major role in cervical cancer of Asian populations. Some amino acid changes in the E6 protein of HPV16 variants affect E6 functions such as p53 interaction and host immune surveillance. This study aimed to investigate activities of HPV16As E6 protein on modulation of expression of miRNA-21 as well as interferon regulatory factors (IRFs) 1, 3, 7 and c-fos. Materials and Methods: Vectors expressing E6 protein of HPV16As (E6D25E) or HPV16 prototype (E6Pro) were constructed and transfected into C33A cells. HCK1T cells expressing E6D25E or E6Pro were established by transducing retrovirus-containing E6D25E or 16E6Pro. The E6AP-binding activity of E6 and proliferation of the transfected C33A cells were determined. MiR-21 and mRNA of interesting genes were detected in the transfected C33A cells and/or the HCK1T cells, with or without treatment by culture medium from HeLa cells (HeLa-CM). Results: E6D25E showed binding activity with E6AP similar to that of E6Pro. Interestingly, E6D25E showed a higher activity of miR-21 induction than did E6Pro in C33A cells expressing E6 protein. This result was similar to the HCK1T cells expressing E6 protein, with HeLa-CM treatment. The miR-21 up-regulation significantly corresponded to its target expression. Different levels of expression of IRFs were also observed in the HCK1T cells expressing E6 protein. Interestingly, when treated with HeLa-CM, IRFs 1, 3 and 7 as well as c-fos were significantly suppressed in the HCK1T cells expressing E6D25E, whereas those in the HCK1T cells expressing E6Pro were induced. A similar situation was seen for IFN-${\alpha}$ and IFN-${\beta}$. Conclusions: E6D25E of the HPV16As variant differed from the E6 prototype in its activities on epigenetic modulation and immune surveillance and this might be a key factor for the important role of this variant in cervical cancer progression.

• 한국미생물·생명공학회지
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• 제32권2호
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• pp.190-194
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• 2004

The gene product of dctD (DctD) activates transcription from the dctA promoter regulatory region by the $\sigma^{54}$ -holoenzyme form ofRNA polymerase ($E\sigma^{54}$ ) in Rhizobium meliloti and R. leguminosarum. The Escherichia coli integration host factor (IHF) stimulated DctD-mediated activation from the dctA promoter regulatory region of R. leguminosarum but not R. meliloti. In the absence of UAS, IHF inhibited DctD-mediated activation from both of these promoter regulatory regions. IHF also inhibited activation from R. leguminosarum dctA by nitrogen regulatory protein C (NtrC), another activator of $E\sigma^{54}$ but not by one which lacks a specific binding site in this promoter regulatory region. IHF, however, stimulated NtrC-mediated activation from the R. meliloti dctA promoter. Upon removal of the UAS, IHF inhibited NtrC-mediated transcription activation from the R. meliloti dctA promoter regulatory region. These data suggest that IHF likely faciliates productive contacts between the activators NtrC or DctD and $E\sigma^{54}$ to stimulate activation from dctA promoter.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 하계학술대회 논문집 Vol.7
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• pp.129-129
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• 2006

인쇄회로를 제작하기 위하여 기판상에 에칭 레지스트, 도금막, 절연재료, 솔더 마스크 등을 패터닝 하게 되는데, 일반적으로 이러한 유기체 막들은 대부분 액상이나 고형의 필름 형태로 패턴을 형성하게 된다. 형성된 패턴과 동박과의 접착력 향상이 가장 주요한 문제점 중의 하나이다. 상대적으로 편평한 동박면과 유기체 막과의 접착력을 향상시키기 위해 일반적으로 접촉 면적을 증가시키기 위한 표면개질을 하게 된다. 기계적 브러싱이나 스크러빙에 의해서도 기판상의 동박의 surface topography 를 개선하기 위한 노력이 시도 되고 있지만, 본 연구에서는 microetching 방법에 의해서 화학적으로 동박 표면상에 최대한 요철을 많이 형성하여 에칭 레지스트와 동박 간의 접착력을 증대시키기 위한 연구를 수행하였다.

• 국제지역연구
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• 제13권1호
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• pp.309-340
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• 2009

다국적기업은 새로운 제조 및 기술을 협업에 의해 개발하기 위하여 점차로 전 세계에 걸쳐 연구개발(R&D)센터를 설치하고 있다. 이러한 범세계적인 현상은 기업의 글로벌 전략과 맞물려 신흥 공업국을 포함하는 추세다. 이는 다국적기업의 전략과 신흥공업국의 개발전략 양자에 있어 더욱 더 그 중요성이 커지고 있다. 본 연구에서는 다국적기업의 R&D이전에 따른 운영활동의 구체적인 요인들을 살펴보고 다국적기업들이 다른 국가에 비해 R&D센터 설립을 선호하는 중국과 한국에서의 R&D센터 운영을 둘러싼 각 요인을 비교 분석한다. 본 연구에서는 다국적기업의 R&D이전과 관련된 8가지 차원을 통하여 특히 입지결정 요인, 시장특성, 정부의 지원정책, R&D네트워킹에 있어 중국과 한국이 큰 차이를 보이고 있음을 밝혀냈다. 또한 다국적기업의 R&D센터 운영과 관련하여 한국보다는 중국이 긍정적인 요인이 많은 것도 비교연구로 나타났다. 본 연구의 결과는 다국적기업의 R&D센터 운영자들과 한국의 다국적기업의 유치와 관련된 정책결정자들에게 많은 시사점을 제공 할 수 있을 것이다.

• 영어어문교육
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• 제18권2호
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• pp.1-20
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• 2012

This study aims to propose using English reading strategies to enhance Intercultural Communicative Competence (ICC) for EFL learners. The study recruited college-level participants who were enrolled in a general English reading course (N=30) and administrated the surveys with a Repeated Measures Design (RMD). In the survey, an intercultural sensitivity scale and metacognitive reading strategies inventory were conducted for comparison. During the instruction, participants were asked to use the R.I.D.E.R. (i.e. Read, Image, Describe, Evaluate, and Repeat) strategy for visualization of text, which is aimed at facilitating the use of metacognitive reading strategies. In the results, participants showed a statistically significant increase both in the intercultural sensitivity level and the use of metacognitive reading strategies after the practice of R.I.D.E.R for one semester. Further analysis was appended to the results by the correlation and regression analysis, and proposed that participants benefit their development of intercultural sensitivity from the use of metacognitive reading strategies. Therefore, the study suggests that implementing metacognitive reading strategies facilitates college EFL readers to increase their cultural sensitivity, which empowers ICC through English reading (176words).