• Title/Summary/Keyword: duration of disease

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Clinical factors causing hyperbilirubinemia in patients with Kawasaki disease (가와사끼병에서 고빌리루빈혈증의 관련인자에 대한 임상적 고찰)

  • Moon, Kyung Hee;Kim, Ok Ran;Yu, Seung Taek;Hong, Myung Eun;Lee, Chang Woo;Choi, Du Young;Oh, Yeon Kyun;Kim, Jong Duk;Yoon, Hyang Suk
    • Clinical and Experimental Pediatrics
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    • v.50 no.1
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    • pp.52-55
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    • 2007
  • Purpose : Hyperbilirubinemia, jaundice and gallbladder hydrops are unusual manifestations of Kawasaki disease (KD). In this case, abdominal pain, anorexia and abdominal distension may follow eventfully. We reviewed the clinical and laboratory data to investigate the causative factors of hyperbilirubinemia in patients with KD. Methods : Two-hundred eighty two children diagnosed and hospitalized with KD were identified by searching patients' charts. Cases were included in the study if diagnosed between January 1997 and December 2004. We reviewed clinical data, age, sex, duration from the onset of fever to admission and duration from start of treatment to defervescence. Clinical and laboratory data were compared between normal (A) and hyperbilirubinemia (B) groups. Results : Thirteen patients (4.6 percent) showed hyperbilirubinemia. In the hyperbilirubinemia group, age and initial ALT value were higher than group A (P=0.003, 0.018 respectively). Duration from the onset of fever to admission and age were relative risk factors in hyperbilirubinemia (P=0.007, 0.003 respectively) in patients with KD. Conclusion : Shorter duration from the onset of fever to admission and older age group were relative risk factors of hyperbilirubinemia in patients with KD.

A Study on the Pain, Fatigue Perceived by Rheumatoid Arthritis Patients (류마티스 관절염 환자가 지각하는 통증과 피로)

  • Yoo, Kyung-Hee
    • The Korean Journal of Rehabilitation Nursing
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    • v.9 no.1
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    • pp.81-86
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    • 2006
  • Purpose: The purpose of this study was to investigate the relationship between the level of pain and fatigue in rheumatoid arthritis patients. Method: The subjects for this study were 120 patients registered in S University Hospital, and the period of data collection was from June 20, 2005 to October 15, 2005. Results: The research instruments used in this study were the Graphic Rating Scale of Pain and Fatigue, and the cronbach's ${\alpha}$ of Fatigue scale was .90. In data analysis, SPSSWIN 12.0 program was used for descriptive statistics. The results were as follows. 1) The range of total pain scores was from 10 to 100 and the mean score of the pain in rheumatoid arthritis patients was 53.70. 2) The range of total fatigue scores was from 20 to 58 and the mean score of the fatigue in rheumatoid arthritis patients was 36.04. 3) There was a significant difference in pain according to duration of disease(F=3.934, p<.05). 4) There was a significant difference in fatigue according to duration of disease(F=3.442, p<.05). 5) The level of fatigue was significant correlation with the level of pain in rheumatoid arthritis patients(r=.217, p<.01). Conclusion: The level of fatigue was significant correlation with the level of pain in rheumatoid arthritis patients. Therefore nursing interventions decreasing the pain perceived by rheumatoid arthritis patients are needed to decrease there fatigue levels.

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Relationship between Pain-related Variables and Extent of Heart Disease (심장질환자에서 흉부 통증 특성과 심장질환 정도와의 관계)

  • Kim, In-Ja
    • The Korean Journal of Rehabilitation Nursing
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    • v.6 no.1
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    • pp.7-13
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    • 2003
  • Purpose: To identify the essential characteristics of pain which nurse have to obtain for patients with chest pain, 92 patients who were admitted in medical units to take intensive tests for heart disease were investigated cross-sectionally. Method: Duration, severity, stress, anxiety, perceived severity, number of painful area, number of accompanying symptoms, triggering activity, and pattern were included as the characteristics of pain. Ejection fraction of left ventricle and number of involved area detected by ultrasonography and number of diseased coronary artery detected by cardiac catheterization were assessed as the variables of heart disease extent. Result: Severity of pain was found to be correlated with all three variables of heart disease extent. Perceived severity and number of accompanying symptoms were correlated with two of them. Anxiety, number of painful area and pattern were related with the number of involved area. Conclusion: Pain severity reported by patients is found to be the most important variable to be obtained from patient. Variables such as perceived severity, number of accompanying symptoms, anxiety, number of painful area and pattern also have to be carefully assessed to anticipate the extent of heart disease.

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Comparision of Myocardial Injury in Cardiac Valvular and Coronary Surgery (심장판막 및 관상동맥 수술시 심근 손상에 대한 비교)

  • 원경준
    • Journal of Chest Surgery
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    • v.27 no.9
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    • pp.738-745
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    • 1994
  • In order to evaluate the myocardial injury in cardiac valvular and coronary surgery, variables of creatine kinase[CK], myocardial band of CK[CK-MB], lactate dehydrogenase[LDH], aspartate aminotrasferase[AST] were measured in the preoperative[Preop], the operation day[POD0], and the first[POD1], third[POD3], fifth[POD5], seventh[POD7], ninth[POD9] day after operation in 29 patients. The subjects were divided into two groups according to the diseases: group V [valvular disease, n=16] and group C[coronary artery disease, n=13]. Each group was subdivided into two subgroups according to the duration of aortic crossclamping time[ACT]; group VI[ACT 120min, n=7] and group VII[ACT>120min, n=9]; group CI[ACT 120min, n=6] and group CII[ACT>120min, n=7]. The results were as followed 1. The values of CK between group V and group C had no significant difference. The values of CK in group CII were significantly greater than those in group CI and the values of CK in group VII were significantly greater than those in group VI. 2. Percentages of CK-MB between groups had no significant difference. 3. The serum levels of LDH in group V were significantly greater than those in group C. The serum levels of LDH in group VII were significantly greater than those in group VI. 4. The serum levels of AST in group VII were significantly greater than that in group VI. We were concluded that myocardial injury was more related with the duration of aortic cross clamping time rather than the type of diseases.

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Effects of 7~11 cycles adjuvant FOLFOX chemotherapy on the prognosis of patients with stage III colon cancer

  • Rhee, Jiyoung;Jo, Jaemin
    • Journal of Medicine and Life Science
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    • v.16 no.1
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    • pp.6-9
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    • 2019
  • Adjuvant fluorouracil, leucovorin, and oxaliplatin (FOLFOX) chemotherapy for 6 months is the standard treatment of stage III colon cancer to improve patient survival. Recent studies have shown that restricting the treatment to 3 months to reduce toxicity negatively affects the outcome. However, the effect of FOLFOX treatment for a duration of between 3 and 6 months(7~11 cycles) on survival is not known. The effect of a reduced duration of FOLFOX chemotherapy on the prognosis of stage III colon cancer was examined. The 5-year disease-free survival in patients receiving 7~11 cycles of FOLFOX was lower than those receiving 12 cycles(72.9% vs. 87%, respectively). Patients receiving 7~11 cycles who had a bowel obstruction at diagnosis had a significantly higher recurrence rate (66.7% vs. 15.0%) and shorter median disease-free survival (24.7 months vs. not reached) than those receiving 12 cycles. Among patients receiving 12 cycles of FOLFOX, there was no difference in the outcome between those with and those without intestinal obstructions at diagnosis. These results suggest that the completion of 12 cycles FOLFOX chemotherapy is important to improve the patient's prognosis, especially for with intestinal obstructions at diagnosis.

Factors Affecting Bone Mineral Density of the Femur in Parkinson's Disease Patients (파킨슨병 환자의 골밀도 영향요인)

  • Kim, Sang Hee;Lee, Eun Nam;Park, Eun Young;Kim, Jae Woo
    • Journal of muscle and joint health
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    • v.19 no.3
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    • pp.350-361
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    • 2012
  • Purpose: The purpose of this study is to explore the level of bone mineral densities of the femur neck and to identify factors affecting bone mineral density of the femur in Parkinson's disease (PD) patients. Methods: Participants were 121 PD patients visiting the outpatient clinic of D University Hospital in B City. Bone mineral density was measured at the femur neck by using a dual-energy x-ray absorptiometry. The serum vitamin D level, the amounts of milk intake, caffeine intake, cigaret smoking, and alcohol consumption, and the number of steps taken daily were measured. Past and present disease history, the medication history, and duration of the disease were also collected. The level of disability was obtained by neurologists using the Hoehn and Yahr stage and the Unified Parkinson's Disease Rating Scale. Results: Among PD patients, 57% had osteopenia and 15.7% had osteoporosis. The bone mineral density of the femur was associated with weight, serum vitamin D level, age, and working status. Conclusion: The identification of weight and serum vitamin D level as important predictive factors emphasizes the importance of balanced nutrition for PD patients.

A Study on Status of Death in Rural Residents (일부(一部) 농촌주민(農村住民)의 사망(死亡) 실태(實態) 조사(調査))

  • Choi, Byung-Ju
    • Journal of Preventive Medicine and Public Health
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    • v.10 no.1
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    • pp.155-159
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    • 1977
  • A study on the status of death in rural area was conducted during the period from July '75 to August '75. 1,225 families and 8,067 population (4,124 male, 3,943 female) had been lived and 149 events of death since 5 years before study were occurred in survey area, Nammyon, Hwasoongun, Chonnam. The summarized results were as follows: 1. Quinquennial death rate was 3.7 (5.2 for male, 2.1 for female). 2. In respect of age group, the highest group was over 70 years old group (age at death, 30.8% of total death). High age groups (over 50 years old) occupied 71.1% of total death and death rate in these groups were higher in male than female. Child death (0-4 years old) occupied 7.4% of total death and infant death rate was higher in female than male. 3. Duration of sickness before die was highest in 1 to 12 months (39.6%) 4. The most frequent cause of death was disease of digestive system (12.1%). Other important causes were disease of circulatory system (10.7%), disease of respiratory system (9.4%) and infectious and parasitic disease (4.7%). Disease of digestive system was the most frequent cause of death in male (14.0%) and disease of respiratory system was the most frequent cause in female (9.5%).

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The Analysis of Risk Factor Management Programs for Patients with Coronary Artery Disease (관상동맥질환자를 위한 위험요인관리 프로그램 분석)

  • Bang, So-Youn;Park, Mi-Young
    • The Korean Journal of Rehabilitation Nursing
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    • v.16 no.1
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    • pp.27-36
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    • 2013
  • Purpose: This study was performed to analyse the trends of risk factor management programs for patients with coronary artery disease. Methods: Using PubMed, 35 intervention studies related to risk factor management programs among randomized controlled trials searched with the key words of coronary artery disease and coronary heart disease. Collected studies were analysed according to the characteristics of studies and participants, method and content of intervention, and outcome indicator and its effects. Results: The mean period of intervention was $28.7{\pm}26.8$ weeks, the mean frequency was $3.0{\pm}2.0$ times per week, and the duration of one session was below 60 minuets in 65.8% of the reviewed studies. The interventions were counselling, exercise, education, and cognitive behavior therapy. Counselling was applied most frequently in previous studies. The outcomes of intervention had been measured with anthropometric, physical, physiological, psychological, behavioral, and cognitive aspects, but the effect of the intervention was inconsistent among the studies. Conclusion: Based on the results of this study, systematic and comprehensive cardiac rehabilitation program consisted of counselling, exercise, and education should be developed and performed for health management and relapse prevention of patients with coronary artery disease.

Effects of Coping on Physical and Psychosocial Adaptation by Illness Duration in Patients with Rheumatoid Arthritis (류마티스 관절염 환자의 질병 기간에 따른 대처 유형과 적응과의 관계)

  • Kim, In-Ja;Suh, Moon-Ja
    • Journal of muscle and joint health
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    • v.5 no.1
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    • pp.26-38
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    • 1998
  • The effects of coping on physical and psychosocial adaptation in the 297 patients with rheumatoid arthritis were investigated. The coping methods were divided into compliance of medical regimens, self-control activities, and cognitive control. The effects of these coping methods was analyzed with stepwise regression. The physical adaptation is found to be significantly affected by cognitive control, self-control activities, and compliance of medical regimens in order Compliance of the medical regimens affects negatively the physical adaptation. And psychosocial adaptation is significantly affected by the cognitive control. The analysis of these results by illness duration showed the distinct differences. That is in the patients who experienced the disease less than 48 months, the physical and the psychosocial adaptation were significantly affected only by the cognitive control. But in the patients who experienced the disease more than 96 months, the physical and the psychosocial adaptation were significantly affected by self-control activities. Based upon these results, it is recommended that the nurses who care the newly diagnosed patients emphasize on the positive side of the state. And the patients who are diagnosed long ago need the nursing programs which teach and promote self-control activities. Also it is suggested that the results of compliance must be considered rather than as the result variable.

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Combination Therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok for the Treatment of Verruca Plana (곽향정기산가미방(藿香正氣散加味方) 투여 및 소장정격(小腸正格) 시술을 이용한 편평사마귀의 치료 효과)

  • Yun, Jeong-Min;Shin, Sang-Ho;Yoon, Hwa-Jung;Ko, Woo-Shin
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.1
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    • pp.169-181
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    • 2010
  • Objective : The purpose of this study was to investigate the effects of Combination therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok on patients with verucca plana. Methods : Sixty-five patients(male 19, female 46) with verruca plana were treated with Gwakhyangjeonggisangamibang and Sojangjeonggyeok for at least 3 months. After treatment, a clearance rate was divided into 4 scales such as; complete clearance / partial clearance-good / partial clearance-poor / no change. Statistical analysis was performed by using Independent-sample t-test. Results : Mean age of patients was 30.3 and mean period of disease duration was 64.6 months. Fifty-eight patients(73.8%) showed complete clearance, nine(13.8%) partial clearance-good, and eight(12.3%) partial clearance-poor. Complete clearance group(CC group) was statistically younger than failure group and disease duration of CC group was shorter than failure group. Although treatment period of failure group was statistically longer than CC group and dosage(貼) of herbal medicine of failure group was more than CC group, failure group showed partial clearance. Conclusion : This data demonstrates that combination therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok could be an effective and safe treatment for the verucca plana.