• 한국임상수의학회지
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• 제25권2호
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• pp.112-114
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• 2008

털응애는 토끼에서 피부 질환을 유발하는 매우 전염성이 강한 인수공통 질병 진드기이다. 본 증례 보고에서는 털응애에 감염된 네 마리의 토끼에 permethrin (65%) 0.1 ml를 1회 피하로 적용하였다. 모든 토끼가 8주 후 부작용 없이 성공적으로 치료되었다. 본 증례에서 permethrin은 토끼 털응애증 치료에 효과적이었다.

• 한국생활과학회지
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• 제5권2호
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• pp.123-130
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• 1996

The purpose of this study is to examine and to evaluate the wearing performance of pile materials to produce velvet fabrics which have excellent wearing comfort. Acetate velvet, Cuprammonium rayon velvet were combined as textiles for clothing and acetate and viscose rayon were as textiles for lining at the environmental condition of temperature $15^{\circ}C,\;18^{\circ}C,\;21^{\circ}C,\;24^{\circ}C$, relative humidity $50{\pm}5%$ and air velocity 0.25 m/sec. Wearing comfort among 4 materials combinations(Aa, Av, Ra, Rv) was examined and compared. The results are as follows. The investigation of mean skin temperature for environmental temperature and material combinations showed that the mean temperature had a significant difference at the p<0.01 level in accordance with environmental temperature and material combinations.(Aa>Av>Ra>Rv) Moreover, in clothing climate only clothing temperature tended to increase almost linearly but at $24^{\circ}C$ there was no significant difference among textiles for lining compared with the other environmental temperatures. In subjective sensations thermal sensation and comfort sensation showed a significant difference in environmental temperatures and materials.(Aa>Av>Ra>Rv) Though a subject felt warmer, more humid, and more uncomfortable at $24^{\circ}C$ for all of the material combinations comparing with the other temperatures, there was no significant difference in materials.

• 한국어병학회지
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• 제22권3호
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• pp.401-406
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• 2009

2008년 5월 제주지역 하천에 소하하는 은어 중 일부개체가 주둥이 부식 또는 체표궤양증상을 보이면서 폐사하였다. 어류 질병원인균 중 부식증 및 체표궤양과 연관성이 높은 Flavobac-terium 속 세균의 분리를 위해 Shu-Shott medium 및 R2A medium에 주둥이 부식 및 체표궤양 부위를 도말하여 배양 하였고, Flavobacterium 속 세균의 전형적인 집락인 pale yellow colony를 분리하였다. 16S rDNA 염기서열 분석결과 Flavobacterium succinicans DSM 4002(Accession NO. AM230492)와 98.27%의 상동성을 보여 F. succinicans JMFL55로 동정하였다.

• 한국임상수의학회지
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• 제26권6호
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• pp.625-627
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• 2009

토끼에서 토끼 매독이라 불리는 Treponematosis는 Treponema cuniculi에 의해 유발되는 전염성 질환이다. 본 증례 보고에서 5 마리의 토끼가 입술, 생식기, 코 주변에 심한 딱지로 내원하였다. 피부 소파 검사와 곰팡이 배양 검사에서 음성이었다. 인체 매독 항체 검사는 양성이었다. 토끼들은 penicillin과 chloramphenicol로 3 주간 치료를 했다. 딱지는 치료 5-7일 후부터 상당히 감소를 했다. 치료 3 주 후 토끼들에게서 딱지는 관찰되지 않았다. 토끼들은 상기의 치료로 부작용 없이 성공적으로 치료되었다.

• Advances in pediatric surgery
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• 제13권2호
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• pp.222-227
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• 2007

A differential diagnosis between the true hermaphroditism (TH) and mixed gonadal dysgenesis (MGD) has important clinical implications for gender assignment and the decision for early gonadectomy; however, variable clinical and histological features frequently lead to the confusion of TH with MGD. A 17-month-old boy was presented with proximal hypospadias with chordee and right non-palpable testis in his scrotum. He also had right auricular anomaly including a separated tragus with skin tag. Left testis was well palpable in his left scrotum. Diagnostic right inguinal exploration showed Mullerian structures such as a gonad like an ovary and a fallopian tube with a uterus, which were removed. Repair of hypospadias and right auricular anomaly was also done. Following ultrasonography (USG) showed a normal looking testis in left scrotum. His chromosome was 45, XO/46, XY. We report a difficult case of mixed gonadal dysgenesis mimicking true hermaphroditism which combines ipsilateral congenital auricular anomaly.

• The Korean Journal of Pain
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• 제18권1호
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• pp.85-88
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• 2005

Encephalitis is known as a rare complication of varicella zoster virus (VZV) reactivation. It is usually regarded as a complication of a cutaneous infection in patients with impaired cellular immunity. The reported incidence of herpetic motor involvement range between 0.5 and 31%, but is possibly more frequent as the weakness is readily obscured by pain. A 53-years-old woman, who presented with severe shoulder pain, fever, headache and seizure, which developed the day after skin eruptions, also developed motor paresis 7 days after the seizure. Her cerebrospinal fluid (CSF) was VZV-Polymerase chain reaction (PCR) negative, but VZV specific IgG antibody positive, and her brain MRI was found to be normal. With the early diagnosis and proper treatment, such as intravenous administration of acyclovir, stellate ganglion block and Yamamoto New Scalp Stimulation (YNSS), the patient completely recovered, without psychoneurological sequelae. Herein, we present this case, with a discussion of the relevant literature on the incidence, pathophysiology, diagnosis and management of central nervous system VZV involvement.

• Food Science and Biotechnology
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• 제17권6호
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• pp.1272-1278
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• 2008

The purpose of this study was to investigate the effects of Kyung Hee Allergic Disease Herbal Formula (KAHF) on atopic dermatitis (AD) and its mode of action. Our clinical study showed KAHF reduced Severity Scoring of Atopic Dermatitis (SCORAD) indexes and subjective symptom scores. In parallel, the decreased levels of interferon (IFN)-$\gamma$ and interleukin (IL)-5 in serum, which contributed to its AD-mitigating effect was observed. To reveal the underlying mechanisms of KAHF in AD, its anti-inflammatory effect on lipopolysaccharide (LPS)-induced responses in RAW 264.7 cells was examined. KAHF was found to significantly inhibit the productions of nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$), and IL-$1{\beta}$ in LPS-stimulated RAW 264.7 macrophages. Consistently, KAHF potently inhibited protein and mRNA expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Furthermore, KAHF inhibited LPS-induced activation of nuclear factor (NF)-$\kappa}B$. Taken together, our data suggest that KAHF has a beneficial effect on several eicosanoid-related skin inflammations, such as atopic dermatitis.

• 대한의용생체공학회:의공학회지
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• 제17권4호
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• pp.499-506
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• 1996

Blood flow velocimeter is an essential device to measure the blood flow in skin tissue. In this study, we developed a high-speed LDV(laser Doppler Velocimeter) that has real time processing capability using a DSP(digital signal processing) chip and is able to continuously measure information about blood-flow based on a noninvasive method using self-mixing type laser diode. This LDV system has a simpler structure than any other typical blood flow velocimeter and is composed of new self-mixing probe, stabilizer circuits DSP board, and interf'ace boule We measured velocity of speaker-unit by operational frequencies to identify Doppler effect of this system, performed clinical experiment on bare finger tip and compared it with a commercial euipment BPM403A(USA).

• 한방안이비인후피부과학회지
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• 제23권1호
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• pp.253-259
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• 2010

Objectives: We investigated $L^*a^*b^*$ and $ITA^{\circ}$ value on the face to correlate the complexion of Korean female with aging theory of Neijing(內經) in Suwen-Shanggutianzhenlun(素問,上古天眞論). Methods: Three hundreds and thirty one Korean females, aged 22-64 years($39.36{\pm}9.71$ years) were participated in this study. We measured the skin properties of the face with Spectrophotometer CM2600d(Minolta, Japan). Trisimulus $L^*a^*b^*$ color and $ITA^{\circ}$ value divided on 7 years were and analyzed by regression analysis method. Results: $L^*$, ITA value decreased and $a^*$, $b^*$ increased as the age increases. Among these, we found out that ITA value is most related to aging. $L^*$ value decreased among the group of 28 to 35 years old. ITA value decreased among the group of 35 to 42 years old. $a^*$ value decreased among the group of 42 to 49 years old. Conclusions: Unique aging pattern by 7 years of female in Oriental medicine is reflected to complexion.

• Mass Spectrometry Letters
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• 제15권1호
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• pp.49-53
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• 2024

Ceramide is a lipid in which sphingoid bases and fatty acids are linked by amide bonds. As a marker of skin disease in the human stratum corneum, its disease-causing and therapeutic effects have been partially confirmed, and it is therefore an important element in commercially available cosmetic formulations. However, structural diversity caused by differences in the chain length, number, and location of hydroxyl groups makes quality control difficult. In this study, a method was established to separate different ceramide species using reversed-phase LC-MS/MS and thus enable qualitative evaluation. Separation of four standards was achieved within a short retention time, and the accuracy and sensitivity of the method were demonstrated by the low limit of detection (LOD) calculated based on the calibration curve showing linearity, with R² > 0.994. After verification of reproducibility and reliability through intra- and inter-day analyses, the efficiency of the method was confirmed through analysis of commercial cosmetic raw materials.