• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.12
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• pp.1416-1426
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• 2008

In this paper, we present a small size and multiband directional dipole antenna for mobile communication repeaters. In the omni-directional dipole antenna, a planar reflector under the dipole provides improved directivity in front-direction with wide beamwidth. In order to miniaturize the directive dipole, the size of the reflector is reduced. A vertical stub on the reflector is proposed to enhance the front-directivity of the radiation pattern and mitigate the backward radiation due to the reduced reflector. Furthermore, we use horizontal stubs on edge of vertical stub to obtain additional reduction of the antenna size. To meet the current demand of wireless communication service, the designed antenna shows wideband characteristic by employing electromagnetic coupled two-dipoles with dual-resonance frequencies.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.10
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• pp.817-820
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• 2018

In this letter, a compact multiple-input multiple-output(MIMO) antenna design for a 2.4 GHz wireless local area network(WLAN) band is proposed for use in smart glasses. To miniaturize the MIMO antenna system, a ground plane is employed within the antenna and a T-shaped ground is proposed. To achieve wideband isolation, dual resonance is formed by the ground mode. One resonance is created by the T-shaped ground and the second resonance is created by adding a slot and a capacitor between the two feed lines. The measurements show that the reflection coefficient characteristic was less than -5.1 dB, whereas the isolation obtained was less than -20 dB. The diversity performance was evaluated using the measured two-dimensional radiation patterns, and the envelope correlation coefficient(ECC) values achieved in the target band(2.4~2.5 GHz) were less than 0.1.

• Transactions of the Korean hydrogen and new energy society
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• v.27 no.4
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• pp.357-364
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• 2016

Recently, the world faces the environmental problem such as air pollution due to harmful gas discharged from car and abnormal climate due to the green-house gases increased by the discharge of $CO_2$. Compressed Natural Gas (CNG), one of alternative for this problem, is less harmful, compared to the existing fossil fuel, as gaseous fuel, and less carbon in fuel ingredients and carbon dioxide generation rate relatively favorable more than the existing fuel. However, CNG fuel has the weakness of slow flame propagation speed and difficult fast burn. On the other hand, hydrogen does not include carbon in fuel ingredients, and does not discharge harmful gas such as CO and HC. Moreover, it has strength of quick burning velocity and ignition is possible with small ignition energy source and it's has wide Lean Flammability Limit. If using this hydrogen with CNG fuel, the characteristics of output and discharge gas is improved by the mixer's burning velocity improved, and, at the same time, is possible to have stable lean combustion with the reduction of $CO_2$ expected. Therefore, this research tries to identify the characteristics of engine and emission gas when mixing CNG fuel and hydrogen in each portion and burning them in spark igniting engine, and grasp the combustion stability and emission gas characteristics according and use it as the basic data of hydrogen-CNG premixed engine.

• Korean Institute of Interior Design Journal
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• v.24 no.2
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• pp.58-66
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• 2015

This study was conducted to determine a 'platform' as a mean of interactions between users in contemporary spatial design and network(web) and to verify the similarity between the platform and space of Rem Koolhaas, one of the leading contemporary architects of our time. A platform, referring to tangible or intangible structures designed for common use in a variety of ways, is activated by the networking effect of participants. Aided by the recent development of the IT industry encompassing computers and smart phones, the concept of platforms is extending to all areas of modern life, in general. In this study, the similarity between architectural space and platforms after reviewing the computer-related platforms, ecological features that refer to virtuous circulation, and various cases applied with platform thinking. Through this process, the platform feature of architectural platforms is defined as the 'open spatial system combined with control and freedom that acts more than one function and facilitates direct/indirect exchanges between users regardless of its type or size'. Establishing the criteria for spatial analysis based on this definition, analysis was conducted on interior design projects that were planned and conducted by Rem Koolhaas after 2000. As a result of this analysis, it was learned that Rem Koolhaas designs space using dual space structures where the extension and mixture of the user group, mixture of various functions defined by users, loose control that induces voluntary participation, community reinforcement, and inducement of accidental events, and opening and closing coexist. In addition, this design approach was found to be a design strategy similar to the concept of platforms that began to be developed in the IT field.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10847-10853
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• 2015

Background: Lapatinib, a dual tyrosine kinase inhibitor that interrupts the epidermal growth factor receptor (EGFR) and HER2/neu pathways, has been indicated to have significant efficacy in treating HER2-positive breast cancer. However, acquired drug resistance has become a very serious clinical problem that hampers the use of this agent. In this study, we aimed to screen small molecule drugs that might reverse lapatinib-resistance of breast cancer by exploring differentially expressed genes (DEGs) via a bioinformatics method. Materials and Methods: We downloaded the gene expression profile of BT474-J4 (acquired lapatinib-resistant) and BT474 (lapatinib-sensitive) cell lines from the Gene Expression Omnibus (GEO) database and selected differentially expressed genes (DEGs) using dChip software. Then, gene ontology and pathway enrichment analyses were performed with the DAVID database. Finally, a connectivity map was utilized for predicting potential chemicals that reverse lapatinib-resistance. Results: A total of 1, 657 DEGs were obtained. These DEGs were enriched in 10 pathways, including cell cycling, regulation of actin cytoskeleton and focal adhesion associate examples. In addition, several small molecules were screened as the potential therapeutic agents capable of overcoming lapatinib-resistance. Conclusions: The results of our analysis provided a novel strategy for investigating the mechanism of lapatinib-resistance and identifying potential small molecule drugs for breast cancer treatment.

• Imaging Science in Dentistry
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• v.44 no.4
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• pp.263-271
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• 2014

Purpose: This study aimed to evaluate the use of dental cone-beam computed tomography (CBCT) in the diagnosis of osteoporosis among menopausal and postmenopausal women by using only a CBCT viewer program. Materials and Methods: Thirty-eight menopausal and postmenopausal women who underwent dual-energy X-ray absorptiometry (DXA) examination for hip and lumbar vertebrae were scanned using CBCT (field of view: $13cm{\times}15cm;$ voxel size: 0.25 mm). Slices from the body of the mandible as well as the ramus were selected and some CBCT-derived variables, such as radiographic density (RD) as gray values, were calculated as gray values. Pearson's correlation, one-way analysis of variance (ANOVA), and accuracy (sensitivity and specificity) evaluation based on linear and logistic regression were performed to choose the variable that best correlated with the lumbar and femoral neck T-scores. Results: RD of the whole bone area of the mandible was the variable that best correlated with and predicted both the femoral neck and the lumbar vertebrae T-scores; further, Pearson's correlation coefficients were 0.5/0.6 (p value=0.037/0.009). The sensitivity, specificity, and accuracy based on the logistic regression were 50%, 88.9%, and 78.4%, respectively, for the femoral neck, and 46.2%, 91.3%, and 75%, respectively, for the lumbar vertebrae. Conclusion: Lumbar vertebrae and femoral neck osteoporosis can be predicted with high accuracy from the RD value of the body of the mandible by using a CBCT viewer program.

• Journal of Navigation and Port Research
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• v.34 no.10
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• pp.775-780
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• 2010

In the machinery, the brake system is as important part as machine's working. The situation of emergency stop, the machine doesn't stopped would be occur big accident. This is common things for all of machinery, also for the ships. There are two kind of mooring devices are existed on the ship. One of them, the windlass winch, is used to anchor. The other, the mooring winch is used to moor the ship in pier use the rope tied to bitt on dock. In case of previously been used mooring winch made of a steel plate, and the bolt which was connect brake band and lining broken. In this study, prevent an accident find the position of stress concentration by finite element analysis program. And removed stress concentration. And search the optimum position of the separation angle to be more efficient.

• Journal of KIISE:Databases
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• v.30 no.2
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• pp.176-183
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• 2003

Various techniques including histograms, sampling and parametric techniques have been proposed to estimate query result sizes for the query optimization. Histogram-based techniques are the most widely used form for the selectivity estimation in relational database systems. However, in the spatio-temporal databases for the moving objects, the continual changes of the data distribution suffer the direct utilization of the state of the art histogram techniques. Specifically for the future queries, we need another methodology that considers the updated information and keeps the accuracy of the result. In this paper we propose a novel approach based upon the duality and the marginal distribution to construct a histogram with very little time since the spatio-temporal histogram requires the data distribution defined by query predicates. We use data synopsis method in the dual space to construct spatio-temporal histograms. Our method is robust to changing data distributions during a certain period of time while the objects keep the linear movements. An additional feature of our approach supports the dynamic update incrementally and maintains the accuracy of the estimated result.

• Molecules and Cells
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• v.37 no.9
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• pp.664-671
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• 2014

MiR-217 can function as an oncogene or a tumour suppressor gene depending on cell type. However, the function of miR-217 in lung cancer remains unclear to date. This study aims to evaluate the function of miR-217 in lung cancer and investigate its effect on the sensitivity of lung cancer cells to cisplatin. The expression of miR-217 was detected in 100 patients by real-time PCR. The effects of miR-217 overexpression on the proliferation, apoptosis, migration and invasion of SPC-A-1 and A549 cells were investigated. The target gene of miR-217 was predicted by Targetscan online software, screened by dual luciferase reporter gene assay and demonstrated by Western blot. Finally, the effects of miR-217 up-regulation on the sensitivity of A549 cells to cisplatin were determined. The expression of miR-217 was significantly lower in lung cancer tissues than in noncancerous tissues (p < 0.001). The overexpression of miR-217 significantly inhibited the proliferation, migration and invasion as well as promoted the apoptosis of lung cancer cells by targeting KRAS. The up-regulation of miR-217 enhanced the sensitivity of SPC-A-1 and A549 cells to cisplatin. In conclusion, miR-217 suppresses tumour development in lung cancer by targeting KRAS and enhances cell sensitivity to cisplatin. Our results encourage researchers to use cisplatin in combination with miR-217 to treat lung cancer. This regime might lead to low-dose cisplatin application and cisplatin side-effect reduction.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.5
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• pp.1702-1707
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• 2010

As quantities of the data that transmitting by the wireless are more increased, the interest and application are extending about 802.11n that uses by combination two existing 20MHz wireless LAN Channel. 802.11n use dual band of 2.4GHz band and 5.8GHz. So this is expected in mass wireless transmission method because of interference evasion effect in compliance with the radio communication of existing 2GHz neighborhood band. Like this 802.11n uses the radio as well and transmits information there is not only a possibility of undergoing an influence in radio wave environment of circumference. Specially the interior environment and outdoor environment is a possibility of saying that will be defined with each other different modeling as affects in radio communication is different. In this paper, we'll compare the influence to RF feature (802.11n) by (Indoor/Outdoor) environment difference through compared with 802.11n RF feature and Network feature in (Indoor/Outdoor) environment and also examine the correlation between RF feature and Network feature.