• Journal of KIBIM
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• v.2 no.1
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• pp.27-39
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• 2012

Public construction projects need complex and multi-functional management skill, since the most of public construction projects are comprised of multi-project and mega-projects. In order to effectively manage construction projects, PMIS is widely used. However the majority of the current PMIS have been developed as a single project-oriented business management system. Thus compatibility problems are encountered during the process of integrating the entire systems to manage the multi-complex projects. In addition, the form of orders applying BIM are increased recently, but the research and development of BIM based PMIS are still lacking. In this study, therefore, the functions of PMIS main objectives based on the analysis of PMIS As-Is and To-Be of PMIS, the dual management system utilizing Internet and Intranet will be proposed to integrate the individual PMIS with Integrated Program Management System. Rather than combining commercial BIM tool and PMIS directly, which is the common method of failure, the sequential process model to adopt BIM based PMIS is also explained. Step-by-step development method of BIM based PMIS is suggested to prepare for the activation of BIM technology in the nearest future.

• Journal of Embryo Transfer
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• v.31 no.3
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• pp.299-305
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• 2016

Although cryopreservation of sperm is routinely used for clinical requirement, it has some problems, such as high generation of reactive oxygen species (ROS) and cold-shock. To reduce the detrimental damage in sperm, anti-oxidants were added to cryoprotectant for sperm. Curcumin is one of anti-oxidants, which are added in cryoprotectants. However, recent studies have demonstrated that curcumin decreases sperm viability and motility. This study was performed to identify the effect of curcumin on hydrogen peroxide ($H_2O_2$)-exposed bovine sperm, which were cryopreserved-thawed. In $H_2O_2$-exposed bovine sperm, reactive oxygen species (ROS) were significantly reduced by treatment with curcumin in a dose-dependent manner (p < 0.05). Among tested concentrations of curcumin (1 to $50{\mu}M$), 30 and $50{\mu}M$ curcumin showed anti-oxidant effect on $H_2O_2$-induced ROS generation. On the other hand, combination of 30 or $50{\mu}M$ curcumin with anti-oxidant $H_2O_2$ increased the percentage of apoptotic sperm compared to only $H_2O_2$ treatment. Sperm viability was also decreased in the combination of 30 or $50{\mu}M$ curcumin with $H_2O_2$ as judged by FDA/PI staining. $H_2O_2$-induced decrease in sperm progressive motility was recovered by treatment with $1{\mu}M$ curcumin. These results show that high concentration of curcumin has anti-oxidant effect, but it has also cytotoxic effect on bovine sperm. Sperm viability and motility might be more affected by cytotoxic signals of curcumin compared to antioxidant signals.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.12
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• pp.8933-8939
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• 2015

In this paper, we designed a multi humanoid robot control method for performing an exhibition that will maximize the efficiency and user convenience and implementation. In recent years, an increasing number of case and to take advantage of the robots in the field performances and exhibitions, plays, musicals, orchestra performances are also various genres. In concert with the existing small humanoid exhibition to source from outside by using a computer and MP3 player and play, while pressing the start button of communication equipment for the show to start the robot began performing with the zoom. Thus, due to the dual source and robot operation and synchronization does not work well is the synchronization of the start of the concert sound starting point of the robot and robot motion and sound are reproduced separately were frequently occurs when you need to restart the show. In addition, when the center of gravity or lose the robots who were present during the performance problems such as performance or intervene to restart the show. In order to overcome this, in this paper, Multi-small humanoid robot was designed to control the efficiency and the user of the GUI-based human interface S/W to maximize convenience, Zigbee communication to transmit a plurality of data in al small humanoid It was used. In addition, targeting a number of the small humanoid robot demonstrated the effectiveness and validity of the user's convenience by gender actual implementation.

• Journal of Acupuncture Research
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• v.26 no.2
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• pp.91-101
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• 2009

Objectives: Osteoporosis is the most common metabolic disease of the bone, and is one of the most important major public health problems world wide. It is more occurred in female than male, but as the osteoporosis of men is increasing, therefore bone fractures of men are increasing. So we investigated the factors which are related to Bone Mineral Density(BMD) of male for prevention of osteoporosis. Methods: We measured the Bone Mineral Density(BMD) of lumbar spine($L_2$-$L_4$) and femoral neck in 5198 male, using dual energy X-ray absorptionmetry(DEXA; DPX-alpha). And then we analysed the 8 factors - age group, bone mass index(BMI), amount of smoking, drinking, exercise, and fast blood sugar, gastric disease, thyroid disease - which are related to BMD of male. Results: 1. In age group according to ${\ll}$Hwangjaenaekyong Somun, 黃帝內徑 素問${\gg}$, T-score was the highest at 17-24(三八歲) years group and decreased rapidly after 57-64(八八歲) years group in both lumbar spine($L_2$-$L_4$) and femoral neck. Therefore we concluded that T-score of male in lumbar spine($L_2$-$L_4$) and femoral neck change according to age group in ${\ll}$Hwangjaenaekyong Somun, 黃帝內徑 素問${\gg}$. 2. In BMI(body mass index), T-score of lumbar spine($L_2$-$L_4$) and femoral neck were the highest in obese group than non-obese group. In comparison of age group according to BMI, T-score of lumbar spine($L_2$-$L_4$) was significant difference in 17-72 years group and T-score of femoral neck was in 25-72 years group. 3. In exercise, T-score of lumbar spine($L_2$-$L_4$) and femoral neck was increasing as exercising more. In comparison of age group according to exercise, Both T -score of lumbar spine and femoral neck were significant difference in 25-72 years old. 4. T-score of lumbar spine($L_2$-$L_4$) was the highest in men who have taken exercise daily, and T-score of femoral neck was the highest in men who have taken exercise 1-3 times for a week. Conclusions : The age group in ${\ll}$Hwangjaenaekyong Somun, 黃帝內徑 素問${\gg}$ is related to BMD of men. And risk factors - BMI, exercise - are related to BMD of men. Therefore we expect that this study will help for prevention of osteoporosis of men.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.101-101
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• 2003

Main strategy for a treatment of Parkinson's disease (PD), due to a progressive degeneration of dopaminergic neurons, is a pharmaceutical supplement of dopamine derivatives or ceil replacement therapy. Both of these protocols have pros and cons; former exhibiting a dramatic relief but causing a severe side effects on long-term prescription and latter also having a proven effectiveness but having availability and ethical problems Embryonic stem (ES) cells have several characteristics suitable for this purpose. To investigate a possibility of using ES cells as a carrier of therapeutic gene(s), human ES (hES, MB03) cells were transfected with cDNAs coding for tyrosine hydroxylase (TH) in pcDNA3.1 (+) and the transfectants were selected using neomycin (250 $\mu /ml$). Expression of TH being confirmed, two of the positive clone (MBTH2 & 8) were second transfected with GTP cyclohydrolase 1 (GTPCH 1) in pcDNA3.1 (+)-hyg followed by selection with hygromycin-B (150 $\mu /ml$) and RT-PCR confirmation. By immune-cytochemistry, these genetically modified but undifferentiated dual drug-resistant cells were found to express few of the neuronal markers, such as NF200, $\beta$-tubulin, and MAP2 as well as astroglial marker GFAP. This results suggest that over-production of BH4 by ectopically expressed GTPCH I may be involved in the induction of those markers. Transplantation of the cells into striatum of 6-OHDA- denervated PD animal model relieved symptomatic rotational behaviors of the animals. Immunohistochemical analyses showed the presence of human cells within the striatum of the recipients. These results suggest a possibility of using hES cells as a carrier of therapeutic gene(s).

• Research in Community and Public Health Nursing
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• v.6 no.1
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• pp.34-54
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• 1995

Occupational health services in Korea have been operated as dual types: one is operated by occupational health care manager and the other is health care agency without their own personnel. The performance of occupational health service should be different due to the variety of characteristics of health care manager and workplace, qualification of health care manager. This study is to analyze performance of occupational health care services with a particular consideration of job, based on comparing those two types of health care management to show on the basic data for the settlement of more qualitative. health care management system at workplace. For this study, total 391 places in Seoul and Inchon city area: 154 places (39.4%) managed by designated. health care manager and 237 places (60.6%) by the agency with their commission are selected as research samples. Tools for data collection are questionnares have been investigated during the period of 20 September 1993-20 December 1993. Those data are compared with percentiles, mean, standard deviation due to the characterstics of each variable and analyzed for impacting factors with relation to the using multiple regression analysis using SPSS PC program, especially using t -test method in order to compare each type of health care management. Conclusions observed from the tests and each comparison could be summerized as follows : 1. Occupational health care have been accomplished at workplaces with designated people than with agencies people, and coverage rate of the occupational health care services has differences, due to management types. The reason of these results is due to visit only one or two times monthly by the agencies, while their own health care manager obsess, at the workplaces all the times. 2. The common sickness management is the most accomplished item in health care area of occupational health care services, while the preventive care and control for the workers who have serious health problems are insufficient in workers health care area. 3. An insufficient accomplishment of overall health education has been shown because it is difficult to perform health education due to almost no chance of the direct introduction at workplaces. Therefore a strong support system for making and supplying the media is necessary in order to activate indirect health education by means of media. 4. Because health care managers and the agencies managers where take the workplaces for this study are almost nurses who have been comparatively high work site rounding rate about an environmental management at the workplaces, that non-profession can also do it, the activities about the professional area not enough. Therefore, an appropriate referral system should be established in order to complement professional area. 5. Two factors which have an effect on the coverage rate of occupational health care services are : one is those from the workplaces such as type of services, the number of workers, the number of harzadous factors and safety & health committee, the other from health care organization about whether there is its own manager or not.

• Strategy21
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• s.39
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• pp.5-46
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• 2016

North Korea's 4th nuclear test on Jan. 6 and following developments once again awakened the world into seriousness of the nuclear matters on the Korean peninsula. On March 2, UNSC adopted Resolution 2270 which is complemented by Seoul government's measures such as withdrawal from the Gaesung Industrial Complex (Feb. 9) and announcement of unilateral sanction (March 8). Seoul government also strongly urged the international community to strangle North Korea's 'financial resources.' The U.S., Japan, China, and other countries have issued unilateral sanctions to complement the UNSC measure. South Korea and the U.S. conducted their annual joint military drill (Resolve-Foal Eagle) in the largest-ever scale. North Korea, however, responded with demonstration of its nuclear capabilities and announcement of de facto 'nuclear-first' politics. North Korea test-fired a variety of delivery vehicles, threatened nuclear strikes against South Korea and the U.S., and declared itself as an 'invincible nuclear power armed with hydrogen bombs' at the 7th Workers 'Party Congress held in May, 2016. Considering the circumstantial evidences, the North's 4th nuclear test may have been a successful boosted fission bomb test. North Korea, and, if allowed to go on with its nuclear programs, will become a nuclear power armed with more than 50 nuclear weapons including hydrogen bombs. The North is already conducting nuclear blackmail strategy towards South Korea, and must be developing 'nuclear use' strategies. Accordingly, the most pressing challenge for the international community is to bring the North to 'real dialogue for denuclearization through powerful and consistent sanctions. Of course, China's cooperation is the key to success. In this situation, South Korea has urgent challenges on diplomacy and security fronts. A diplomatic challenge is how to lead China, which had shown dual attitudes between 'pressure and connivance' towards the North's nuclear matters pursuant to its military relations with the U.S, to participate in the sanctions consistently. A military one is how to offset the 'nuclear shadow effects' engendered by the North's nuclear blackmail and prevent its purposeful and non-purposeful use of nuclear weapons. Though South Korea's Ministry of Defense is currently spending a large portion of defense finance on preemption (kill-chain) and missile defense, they pose 'high cost and low efficiency' problems. For a 'low cost and high efficiency' of deterrence, South Korea needs to switch to a 'retaliation-centered' deterrence strategy. Though South Korea's response to the North's nuclear threat can theoretically be boiled down into dialogue, sanction and deterrence, now is the time to concentrate on strong sanction and determined deterrence since they are an inevitable mandatory course to destroy the North' nuclear-first delusion and bring it to a 'real denuclearization dialogue.'

• Tunnel and Underground Space
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• v.28 no.3
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• pp.258-276
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• 2018

The accurate and quantitative ground information on the hydraulic conductivity characteristics of rock mass is one of the key factors for evaluation of the hydro-geological behaviour of rock mass around an excavated opening under high water pressure. For tunnel and rock structures in seabed, where the sea acts as an infinite source of water, its importance become greater with increasing construction depth below sea level. In this study, to improve the problems related with poor system configuration and incorrect data acquisition of previous hydraulic packer testing equipment, we newly developed an integrated main frame and 30 bar level waterproof downhole sonde apparatus, which were optimized for deep hydraulic packer test in seabed rock mass. Integration of individual test equipment into one frame allows safe and efficient field testing work on a narrow offshore drilling platform. For the integrated type main frame, it is possible to make precise stepwise control of downhole net injection pressure at intervals of $2.0kg_f/cm^2$ or less with dual hydraulic oil volume controller. To ensure the system performance and the operational stability of the prototype mainframe and downhole sonde apparatus, the field feasibility tests were completed in two research boreholes, and using the developed apparatus, the REV(Representative Elementary Volume) scale deep hydraulic packer tests were successfully carried out at a borehole located in the basalt region, Jeju. In this paper, the characteristics of the new testing apparatus are briefly introduced and also some results from the laboratory and in-situ performance tests are shown.

• Journal of radiological science and technology
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• v.29 no.3
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• pp.177-184
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• 2006

Purpose: To evaluate the correlation between BMD and life habit such as drinking. exercise smoking or physical condition such as age, sex, height, weight, body mass index(BMI). Materials and Methods: I evaluated the BMD of the femoral neck and L2-L4 spines of 321 persons who took a regular health screening in Woosuk university oriental medical hospital from February to April in 2006 by dual energy bone mineral densitometry. Results: The age of persons ranged from 20 years to 75 years(mean $45.10{\pm}11.54$) and there were 160 males and 161 females. In males, BMD of the femoral head was highest at 2nd decade, BMD of the spine was highest at 4th decade, and BMD of both femoral head and lumbar spine was lowest at 6th decade. In fenales, BMD of both femoral head and lumbar spine was highest at 4th decade and lowest at 6th decade. Among the various physical conditions, only height of persons showed significant correlation with BMD in both males and females. BMD was increased according to increasing height. In males, BMD of persons who had habit such as drinking, exercise or smoking did not show significant change statistically. But in females, drinking group showed high BMD relative to non-drinking group in both femoral head and lumbar spine. Conclusion: BMD was different according to age, sex, height and life habit. Especially aged people showed osteoporotic change progressively. More persistent effort is needed to find out the factors decreasing BMD for prevention of problems by osteoporosis.

• The Journal of the Korea Contents Association
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• v.18 no.8
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• pp.392-407
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• 2018

This study aims to prove the mediating effect of emotion dysregulation and perceived social support in the relationship between covert narcissism on the relation addiction. The researchers surveyed college students for about 3 weeks through a questionnaire on college campus or with the help of their colleagues and professors. The subjects were 362 students. SPSS, AMOS and Mplus were used for statistical analysis, correlation analysis and structural equation analysis. The conclusions are as follows : First, emotion dysregulation, relation addiction and covert narcissism showed positive correlation and covert narcissism, emotion dysregulation, relation addiction and perceived social support showed a significant negative correlation. Second, it was found that after investigating the mediation effect of emotion dysregulation and perceived social support in the influence between covert narcissism and relation addiction, emotion dysregulation turned out to have a significant mediating effect while perceived social support did not. Third, dual mediating effect was significant in emotion dysregulation and perceived social support in the influence between covert narcissism and relation addiction. These findings proved that covert narcissism, emotion dysregulation, perceived social support are variables that effect relation addiction, and also clarified that emotion dysregulation is a strong mediating variable in the influence between covert narcissism and relation addiction. Finally, when counseling a client with the same tendency as covert narcissism, it gives an opportunity to be aware of the emotional problem and an opportunity to positively perceive its own social resources, so as not to reach interpersonal problems such as relationship addiction pointed out the need for an approach.