• Title/Summary/Keyword: dose assessment

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Development of Predictive Model for Annual Mean Radon Concentration for Assessment of Annual Effective dose of Radon Exposure (라돈 노출 유효선량 평가를 위한 연간 평균 라돈 농도 예측모델 개발)

  • Lee, Cheolmin;Kang, Daeyong;Koh, Sangbaek;Cho, Yongseog;Lee, Dajeong;Lee, Sulbee
    • Journal of Environmental Science International
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    • v.25 no.8
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    • pp.1107-1114
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    • 2016
  • This research, sponsored by the Korean Ministry of Environment in 2014, was the first epidemiological study in Korea that investigated the health impact assessment of radon exposure. Its purpose was to construct a model that calculated the annual mean cumulative radon exposure concentrations, so that reliable conclusions could be drawn from environment-control group research. Radon causes chronic lung cancer. Therefore, the long-term measurement of radon exposure concentration, over one year, is needed in order to develop a health impact assessment for radon. Hence, based on the seasonal correction model suggested by Pinel et al.(1995), a predictive model of annual mean radon concentration was developed using the year-long seasonal measurement data from the National Institute of Environmental Research, the Korea Institute of Nuclear Safety, the Hanyang University Outdoor Radon Concentration Observatory, and the results from a 3-month (one season) survey, which is the official test method for radon measurement designated by the Korean Ministry of Environment. In addition, a model for evaluating the effective annual dose for radon was developed, using dosimetric methods. The model took into account the predictive model for annual mean radon concentrations and the activity characteristics of the residents.

Estimation of the Number of Salmonellosis Using Microbial Risk Assessment Methodology (미생물 위해성 평가 방법을 이용한 살모넬라 발생수 추정)

  • 최은영;박경진
    • The Korean Journal of Community Living Science
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    • v.15 no.2
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    • pp.167-177
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    • 2004
  • The number of foodborne salmonellosis was estimated by using microbial risk assessment(MRA) methodology and the possibility of application was studied through comparison with previous results. The contamination levels of Salmonella sp. were estimated by using published domestic studies(1997∼2000) and monitoring data (1999∼2001) from food-safety related institutes. Data on food consumption came from the 2001 National Health and Nutrition Survey, and dose-response models from studies in other countries. Simulation results showed that there were 753,368 cases of salmonellosis in Korea in 1 year, which is about 115 times that reported in previous years and lower than the WHO's estimation increase. From these results, microbial risk assessment is likely to be available for estimation of the number of foodborne illnesses and determination of the order of priority in food-safety management. Butthe verification methods are not established and most of the data on contamination levels of foodborne bacteria, food consumption, and dose-response relationships have not been established. In addition, the actual conditions of circulation, storage and cooking must be studied further.

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Assessment of dose effects on image quality at chest computed radiography (흉부 CR 영상에서 선량이 화질에 미치는 영향에 대한 평가)

  • Kang, Bo-Sun
    • Journal of the Korean Society of Radiology
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    • v.5 no.6
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    • pp.421-426
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    • 2011
  • This research was accomplished to assess dose effects on image quality at computed radiography (CR). The ultimate target of the research was finding optimized exposure that provides necessary image quality for the clinical chest diagnosis. Modulation transfer function (MTF), normalized noise power spectrum (NNPS), and Noise equivalent quanta (NEQ) corresponding to the different doses were measured for the assessment of image quality. The preparation of "edge test device" used in MTF measurement and experimental geometry setup were followed by the recommendations of International Electrotechnical Commission (IEC). The experimental results show the necessary image quality can be achieved even at a half of the automatic exposure control (AEC) setting dose for chest diagnosis. It means that the patient exposure can be reduced dramatically by using optimized dose.

Effects of Exposure Dose Reduction by Optimization of Automatic Exposure Control Factors in Digital Radiographic Examination of Paranasal Sinus (부비동 디지털 엑스선검사에서 자동노출제어 조절인자의 최적화를 통한 조사선량 감소 효과)

  • Jeong, Min-Gyu;Seoung, Youl-Hun
    • Journal of radiological science and technology
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    • v.44 no.3
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    • pp.173-181
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    • 2021
  • The purpose of this study was to reduce dose while maintaining image quality during digital radiographic examination of paranasal sinus by using the automatic exposure control (AEC) system. The tube voltage was set as six stages that increased by about 10 kVp to 70 kVp, 81 kVp, 90 kVp, 102 kVp, 109 kVp and 117 kVp. And then the AEC system conditions were consisted of 9 setting environments, that change mode of the sensitivity (S200, S400, S800) and the density (+2.5, 0, -2.5). We measured automatically exposed tube current (mAs) under 54 conditions with combined these, and assessed SNR and PSNR through the acquired images. In addition, four radiologists performed a qualitative assessment of the acquired images for each combination on a five-point scale of the Likert. As a result, the lowest dose and the highest values of SNR and PSNR in images with a qualitative assessment more than 4 point were the AEC control factors of 90 kVp, S800, D2.5. We applied this condition to the clinical trial, it showed an effect of 83.1% reduction in exposure radiation dose (mR). Therefore, AEC system could be used as dose reduction technology if it understood and used related regulatory factors and physical characteristics.

Single oral toxicity test and safety classification for Kaempferia parviflora (흑생강의 단회투여독성시험과 안전성등급화)

  • Han, Young-Hoon;Park, Yeong-Chul
    • The Korea Journal of Herbology
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    • v.33 no.4
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    • pp.53-58
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    • 2018
  • Objectives : Kaempferia parviflora Rhizome is black ginger indigenous to Laos and Thailand. It has been used as a folk medicine to improve blood flow and promote vitality and longevity with good health and well being. For these reasons, Kaempferia parviflora Rhizome has been focused on developing it as a food or food supplement. In addition, Kaempferia parviflora Rhizome could be under consideration of new prescription based on its characteristic compounds, polymethoxyflavonoids. However, it needs to be certified as safe before it can be used. Here, a single-oral toxicity test and safety classification was carried out to identity acute information of the toxicity of Kaempferia parviflora Rhizome powder and to make sure of its safety in clinical applications. Methods : Test substance was orally administered to male and female SD-rat at dose levels of 5000 mg/kg to estimate approximate lethal dose(ALD). Based on the acute information of the toxicity, the safety classification was estimated using the HED(human equivalent dose)-based MOS(margin of safety). Results : At 14 days after treatment with test substance. there were no of test substance related with mortalities and clinical signs. In addition, no changes in the body or organ weights and no gross or histopathological findings were observed. Thus, the ALD of Kaempferia parviflora Rhizome powder was considered over 5,000 mg/kg in both female and male mice. Conclusions : Based on the single oral toxicity test using the highest and limit dose, 5,000 mg/kg and the decision guideline for safety classification based on HED-based MOS, it was estimated that Kaempferia parviflora Rhizome powder is classified as "Specified class B" indicating that clinical dose is not limited to patients as safe as food.

A Study on Estimation of Radiation Exposure Dose During Dismantling of RCS Piping in Decommissioning Nuclear Power Plant

  • Lee, Taewoong;Jo, Seongmin;Park, Sunkyu;Kim, Nakjeom;Kim, Kichul;Park, Seongjun;Yoon, Changyeon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.19 no.2
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    • pp.243-253
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    • 2021
  • In the dismantling process of a reactor coolant system (RCS) piping, a radiation protection plan should be established to minimize the radiation exposure doses of dismantling workers. Hence, it is necessary to estimate the individual effective dose in the RCS piping dismantling process when decommissioning a nuclear power plant. In this study, the radiation exposure doses of the dismantling workers at different positions was estimated using the MicroShield dose assessment program based on the NUREG/CR-1595 report. The individual effective dose, which is the sum of the effective dose to each tissue considering the working time, was used to estimate the radiation exposure dose. The estimations of the simulation results for all RCS piping dismantling tasks satisfied the dose limits prescribed by the ICRP-60 report. In dismantling the RCS piping of the Kori-1 or Wolsong-1 units in South Korea, the estimation and reduction method for the radiation exposure dose, and the simulated results of this study can be used to implement the radiation safety for optimal dismantling by providing information on the radiation exposure doses of the dismantling workers.

Preparation of Radiological Environmental Impact Assessment for the Decommissioning of Nuclear Power Plant in Korea (국내 원전 해체시 방사선환경영향평가 방안)

  • Lee, Sang-Ho;Seo, Hyung-Woo;Kim, Chang-Lak
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.16 no.1
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    • pp.107-122
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    • 2018
  • Kori unit 1, the oldest commercial nuclear power plant in South Korea, was permanently shut down in June 2017. There are a lot of things to consider in decommissioning nuclear power plants, and one of them is the radiological environmental impact assessment. Performed to promote the health and safety of residents around the nuclear power plant, radiological environmental impact assessment aims to confirm that off-site radiological dose from radioactive material released from the facility does not exceed the regulatory criteria. There are three main parts of environmental impact assessment: pre-decommissioning environmental monitoring, environmental monitoring during decommissioning, and impact on nearby residents. At present, although the Korea Nuclear Safety Act stipulates that radiological environmental impact assessment resulting from decommissioning should be carried out, the details have not been specified. Therefore, this paper compares and analyzes guidelines for evaluation of radiological environmental impacts of nuclear power plants overseas, and presents a draft on the assessment of radiological dose resulting from decommissioning according to the Korean situation.

Human Dermal Risk Assessment on Chlorpyrifos of Korean Farmers (우리나라 농민의 Chlorpyrifos에 대한 피부 위해성 평가)

  • 정경미;이효민;이은희;이선희;김진화;심영용;홍진태;이용욱
    • Environmental Mutagens and Carcinogens
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    • v.22 no.3
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    • pp.187-198
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    • 2002
  • Chlorpyrifos is an organophosphate insecticide and one of the most commonly and widely used insecticide. However, a little known about the dermal risk of chlorpyrifos on human being. Therefore, this study was conducted for the dermal risk assessment after exposure to chlorpyrifos in Korean farmers. First, skin irritation by chlorpyrifos (10 mg/$\textrm{cm}^2$, 50 mg/$\textrm{cm}^2$, 100 mg/$\textrm{cm}^2$, 250 mg/$\textrm{cm}^2$ in acetone) was determined in rabbits for 5 days considering the usage of chlorpyrifos short term highly exposure. The index of skin irritation by chlorpyrifos was increased in each dose and length of exposure dependent manners. Next, using benchmark dose (BMD$_{5}$) approach, the dose-response relationship was assessed to calculate the reference dose (RfD). The value of RfD was 2.84 $\mu\textrm{g}$/kg/day from 142.16 $\mu\textrm{g}$/kg/day BMD5 value divided uncertainty factor 50. Finally, we assessed human dermal risk of chlorpyrifos with exposure level and RfD. Skin absorbed levels were assumed with several exposure scenarios encounting the circumstances of exposure that application method, protection equipment and cloth, exposure time and exposure frequency during chlorpyrifos spraying. By the comparison of skin absorbed dose with the reference dose, it was identified that risk values (risk index) to skin chlorpyrifos exposure were 0.958 from the point of above results and it was recommended that the occurrence of hazard effect (skin irritation toxicity) of chlorpyrifos would not be expected. Risk index was smaller than 1 in the case of spraying vehicle mounted application, 1hour exposure time and wearing protective cloth exposure. Whereas, risk index was above 1 in the case of hand-held application, 2hour exposure time and wearing common cloth. Comparing two kinds of application method, total risk index of the hand held application (1.67) was higher than vehicle mounted (0.27). Therefore, chlorpyrifos skin exposure was mainly affected by application equipment and applied form. The results of risk assessment on the human dermal toxicity of chlorpyrifos should be required to control in keeping safety rules, skin surface area available for contact, spraying time ,and spraying frequency.y.

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Developments of Space Radiation Dosimeter using Commercial Si Radiation Sensor (범용 실리콘 방사선 센서를 이용한 우주방사선 선량계 개발)

  • Jong-kyu Cheon;Sunghwan Kim
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.367-373
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    • 2023
  • Aircrews and passengers are exposed to radiation from cosmic rays and secondary scattered rays generated by reactions with air or aircraft. For aircrews, radiation safety management is based on the exposure dose calculated using a space-weather environment simulation. However, the exposure dose varies depending on solar activity, altitude, flight path, etc., so measuring by route is more suggestive than the calculation. In this study, we developed an instrument to measure the cosmic radiation dose using a general-purpose Si sensor and a multichannel analyzer. The dose calculation applied the algorithm of CRaTER (Cosmic Ray Telescope for the Effects of Radiation), a space radiation measuring device of NASA. Energy and dose calibration was performed with Cs-137 662 keV gamma rays at a standard calibration facility, and good dose rate dependence was confirmed in the experimental range. Using the instrument, the dose was directly measured on the international line between Dubai and Incheon in May 2023, and it was similar to the result calculated by KREAM (Korean Radiation Exposure Assessment Model for Aviation Route Dose) within 12%. It was confirmed that the dose increased as the altitude and latitude increased, consistent with the calculation results by KREAM. Some limitations require more verification experiments. However, we confirmed it has sufficient utilization potential as a cost-effective measuring instrument for monitoring exposure dose inside or on personal aircraft.