• Asian-Australasian Journal of Animal Sciences
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• 제20권3호
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• pp.328-333
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• 2007

Carboxypeptidase E (CPE) plays an important role in the regulation of the body fat content. Therefore, it has been suggested as candidate gene for traits related to meat quality in beef cattle. This study was conducted to identify single nucleotide polymorphisms (SNPs) in the CPE gene and to investigate association of SNP marker with carcass and meat quality traits in Korean cattle. Three SNPs were identified in the intron 4 (A309G SNP and C445T SNP) and exon 5 (C601T SNP) of the CPE gene by sequence analyses of CPE cDNA and genomic DNA samples. The sequences have been deposited in GenBank database with accession numbers AY970664 and AY970663. Genotyping of the gene-specific SNP marker was carried out using the PCR-RFLP with restriction enzymes DdeI for C445T SNP and NlaIII for C601T SNP. The frequencies of C and T alleles were 0.43 and 0.57 for C445T SNP and 0.42 and 0.58 for C601T SNP, respectively. Statistical analysis indicated that the C445T SNP showed a significant effect (p<0.05) on marbling score (MS) and breeding value of backfat thickness (BF-EBV), respectively. Animals with the CT genotype showed higher marbling score and backfat thickness than those with the TT genotype. This marker also showed a significant dominance effect for the MS and BF-EBV (p<0.05). However, no significant associations were observed between C601T SNP genotypes and all traits examined. The results suggest that the CPE gene may be used as a marker for carcass traits in Korean cattle.

• The Korean Journal of Physiology and Pharmacology
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• 제14권5호
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• pp.337-343
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• 2010

Long-term potentiation (LTP) and long-term depression (LTD) have both been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. In a previous study, we suggested that a developmental increase in serotonin [5-hydroxytryptamine (5-HT)] might be involved in the decline of LTP, since 5-HT inhibited its induction. In the present study, to further understand the role of 5-HT in a developmental decrease in plasticity, we investigated the effect of 5-HT on the induction of LTD in the pathway from layer 4 to layer 2/3. LTD was inhibited by 5-HT ($10{\mu}M$) in 5-week-old rats. The inhibitory effect was mediated by activation of 5-$HT_2$ receptors. Since 5-HT also regulates the development of visual cortical circuits, we also investigated the role of 5-HT on the development of inhibition. The development of inhibition was retarded by chronic (2 weeks) depletion of endogenous 5-HT in 5-week-old rats, in which LTD was reinstated. These results suggest that 5-HT regulates the induction of LTD directly via activation of 5-$HT_2$ receptors and indirectly by regulating cortical development. Thus, the present study provides significant insight into the roles of 5-HT on the development of visual cortical circuits and on the age-dependent decline of long-term synaptic plasticity.

• 농업과학연구
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• 제38권4호
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• pp.673-680
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• 2011

The aim of this study was to identify the polymorphism on fatty acid binding protein (FABP4) gene promoter region and its association with carcass traits in Hanwoo. We performed PCR-direct sequencing of FABP4 promoter region to identify single nucleotide polymorphism (SNPs) using unrelated 24 Hanwoo bulls. Four SNPs (-298A>G, -472A>G, -887A>G, -862A>G) were detected in the promoter region and genotyped on 583 Hanwoo steers. A linear mixed model revealed an association of three SNPs (-298A>G, -472A>G and -862A>G) with carcass weight and marbling score in dominance model (P<0.05). The animals with AA genotypes for the three SNPs were heavier carcass weight (5 kg) than animals with GG genotypes in the statistical analysis. For the marbling score, the AA genotype was lower effect of marbling score (0.21) than GG genotypes. In conclusion, this study indicates an important role for three SNPs detected in promoter region of FABP4 in determining carcass weight and marbling score in Hanwoo.

• Clinics in Shoulder and Elbow
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• 제17권2호
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• pp.57-63
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• 2014

Background: To compare the effect of different starting periods of rehabilitative exercise (early or delayed passive exercise) on the rate of retear and other clinical outcomes after the arthroscopic repair of the rotator cuff. Methods: In total, 103 patients who underwent arthroscopic repair of the rotator cuff were included in the study. Determined at 2 weeks post-operation, patients who were incapable of passive forward elevation greater than $90^{\circ}$ were allotted to the early exercise group (group I: 79 patients; 42 males, 37 females), whilst those capable were allotted to the delayed exercise group (group II: 24 patients; 14 males, 10 females). The group I started passive exercise, i.e. stretching, within 2 weeks of operation, whilst group II started within 6 weeks. The results were compared on average 15.8 months (11-49 months) post-operation using the passive range of motion, the Visual Analog Scale (VAS) pain score, and the University of California at Los Angeles (UCLA) and Constant scores. Stiffness was defined as passive forward elevation or external rotation of less than $30^{\circ}C$ compared to the contralateral side. Follow-up magnetic resonance imaging (MRI) was carried out on average 1 year post-operation and the rate of retear was compared with Sugaya's criteria. Results: There were no differences between the two groups in gender, age, smoking, presence of diabetes, arm dominance, period of tear unattended, pre-operative range of motion, shape and size of tear, degree of tendon retraction, and tendon quality. There were no significant differences in clinical outcomes. Whilst stiffness was more frequent in group II (p-value 0.03), retear was more frequent in group I (p-value 0.028) according to the MRI follow-up. Conclusions: During rehabilitation after the arthroscopic repair of the rotator cuff, the delay of passive exercise seems to decrease the rate of retear but increase the risk of stiffness.

• 대한금속재료학회지
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• 제48권8호
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• pp.757-764
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• 2010

We report on the effect of additives on the microstructure and corrosion properties of electrodeposited Cu films. Copper films were fabricated by electrodeposition on various concentrations of gelatin in a copper sulfate electrolyte. The surface morphologies of the Cu films were observed using a scanning electron microscope (SEM), and crystal orientation of the Cu films was analyzed by X-ray diffraction measurement. (220) plane was the dominant orientation when the films were fabricated at ambient temperature, decreasing in dominance with addition of gelatin. On the other hand, (111) plane-Cu films were preferentially grown at $40^{\circ}C$, and were also diminished with adding additives. Corrosion rate measurements using the Tafel extrapolation method based on corrosion potential and current reveal the effect of additives on corrosion behavior. Corrosion behavior was found to be strongly related to the orientation of the films. Consequently, additives like gelatin influence crystal orientation of the films, and if a less dense crystal plane, e.g. (220), is preferentially oriented during electrodeposition, a lower corrosion rate could be produced, since the plane shows a lower current density.

• 국제물리치료학회지
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• 제10권1호
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• pp.1700-1705
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• 2019

Background: Mild cognitive impairment (MCI) is also called as aging related memory damage. Decreased cognitive function due to aging is known to be associated with the frontal lobe. Alpha wave is generated in the dominance in the frontal lobe or a wide range of regions in the brain, it should be doubted that the brain function might be degraded. Objective: To determine the effect of sensory stimulation type on learning and brain activity pattern of elderly persons with MCI. Design: Randomized Controlled Trial (single blind) Methods: Twenty elderly persons aged more than 65 with MCI were randonmized to simultaneous visual/auditory stimulation group (SVASG) and or auditory stimulation group (ASG). Ten peoples were assigned to each group and lectroencephalogram test was performed to individuals. In the electroencephalogram test, electroencephalography of prior to sensory stimulation, and during sensory stimulation were measured to compare brain activity pattern according to the study groups and measurement period. Results: The relative alpha power due to a sensory stimulation type showed that the SVASG significantly decreased in the left frontal lobe and the left parietal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). The relative beta power due to a sensory stimulation type showed that the SVASG significantly increased in the left and right frontal lobes, the left and right parietal lobes, and the left temporal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). Conclusions: Electroencephalographic analysis showed that the type of sensory stimulation can affect the brain activity pattern. However, the effects were not studied that which brain activity pattern help to improved cognitive function of elderly persons with mild cognitive impairment.

• Journal of Ecology and Environment
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• 제45권3호
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• pp.97-104
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• 2021

Background: Asarum sieboldii Miq., a species of forest understory vegetation, is an herbaceous perennial belonging to the family Aristolochiaceae. The metapopulation of A. sieboldii is distributed sparsely and has a short seed dispersal distance by ants as their seed distributor. It is known that many flowers of A. sieboldii depend on self-fertilization. Because these characteristics can affect negatively in genetic structure, investigating habitat structure and assessment of genetic structure is needed. A total of 27 individuals in a valley were sampled for measuring genetic diversity, genetic distance, and genetic differentiation by RAPDPCR. Results: The habitat areas of A. sieboldii metapopulation were relatively small (3.78~33.60 m²) and population density was very low (five to seven individuals in 20×20 m quadrat). The habitat of A. sieboldii was a very shady (relative light intensity = 0.9%) and mature forest with a high evenness value (J = 0.81~0.99) and a low dominance value (D = 0.19~0.28). The total genetic diversity of A. sieboldii was quite high (h = 0.338, I = 0.506). A total of 33 band loci were observed in five selected primers, and 31 band loci (94%) were polymorphic. However, genetic differentiation along the valley was highly progressed (G_st = 0.548, N_m = 0.412). The average genetic distance between subpopulations was 0.387. The results of AMOVA showed 52.77% of variance occurs among populations, which is evidence of population structuring. Conclusions: It is expected that a small-scale founder effect had occurred, an individual spread far from the original subpopulation formed a new subpopulation. However, geographical distance between individuals would have been far and genetic flow occurred only within each subpopulation because of the low density of population. This made significant genetic distance between the original and new population by distance. Although genetic diversity of A. sieboldii metapopulation is not as low as concerned, the subpopulation of A. sieboldii can disappear by stochastic events due to small subpopulation size and low density of population. To prevent genetic isolation and to enhance the stable population size, conservative efforts such as increasing the size of each subpopulation or the connection between subpopulations are needed.

• 한국응용과학기술학회지
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• 제40권3호
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• pp.579-588
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• 2023

본 연구는 퍼스널트레이너-고객 간의 라포형성이 운동성과에 미치는 영향관계를 커뮤니케이션 스타일을 중심으로 인과 관계(SEM)를 밝히고자 하였다. 이에 2022년 10월 1일부터 4월 28일까지 표본계획에 의해 PT고객 187명을 대상으로 모바일 프로그램 '서베이몽키'를 통해 다음과 같은 결과를 도출 하였다. 첫째, 커뮤니케이션 스타일은 라포형성에 영향(+)을 미치는 것으로 나타났다. 둘째, 커뮤니케이션 스타일은 운동성과에 부분적으로 영향(+)을 미치며, 통제형은 영향관계가 성립되지 않았다. 셋째, 라포형성이 운동성과에 영향을 미치는 것으로 나타났다. 따라서 PT는 일반적인 서비스가 아닌 인적 서비스이기에 그 중요성이 더욱히 강조되어야 될 것이다. 또한, 치열한 PT시장에서 우위를 점하는 것은 바로 고객이 반응할 수 있는 표현방식 언어적 측면과 비언어적 측면을 적절하게 반영된다면 운동성과와 경영성과 둘 동시 영향을 줄 것으로 판단된다.

• 한국해안·해양공학회논문집
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• 제27권3호
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• pp.149-158
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• 2015

경기만 한강하구에서 주요 수로의 조석 전파 특성을 이용하여, 천문조, 배조 및 복합조의 분포를 파악하고, 조석 형태수의 특징에 따라 구역별 조석체계 (tidal regime)를 분류하였다. 주요 수로에서 보이는 조석 전파 특성은 외해는 천문조로 대표되는 5대분조 (e.g., $M_2$, $S_2$, $N_2$, $K_1$ 및 $O_1$)가 지배적이지만, 상류로 진입할수록 천해 분조 (e.g., $M_4$)와 장주기 분조 (e.g., $MS_f$)의 뚜렷한 증가가 보인다. 반일주조 성분이 우세한 경기만 및 한강하구에서 천문조, 배조 및 복합조를 이용하여 제시된 조석 형태수 (tidal form number)의 특성에 따라 크게 3구역으로 분류하였다. 1구역은 천문조가 우세한 지역으로 외해에서 인천항 전면까지 (염하수로), 외해에서 석모수로의 북쪽 입구로 제시된다. 2구역은 염하수로 남쪽 입구에서 북쪽 입구까지와 강화 북수로 지역으로 단주기 천해 분조 (e.g., $M_4$와 $MS_4$)가 강하게 나타나는 지역이다. 마지막으로 3구역은 신곡 수중보 이후부터 한강 상류지역으로 장주기 복합조 (e.g., $MS_f$)가 제일 우세한 지역이다. 일반적인 하구와 마찬가지로 한강하구의 조석 비선형성은 지형적 특성에 기인한 천해 분조가 증가를 하며, 1/4일주기 (fourth-diurnal) 및 장주기 (long-term period) 분조의 확연한 분포 차이를 보인다. 특히, 수중보의 영향은 구조물의 상류와 하류지점의 조석체계에 지대한 변화를 일으킨다.

• 한국조리학회지
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• 제22권2호
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• pp.206-221
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• 2016

스마트 폰 확산과 배달 앱의 이용 증가로 인해 배달 앱 이용 시 소비자가 지각하는 감정반응과 앱 이용의도에 관한 연구의 필요성을 제시하였다. 따라서 본 연구에서는 배달 앱에 대한 이용의도를 높일 수 있는 변수로 배달 앱의 서비스품질과 PAD의 2가지 감정차원, 각성과 즐거움을 제시하여 그 역할을 규명하고자 하였다. 이러한 분석결과를 토대로 배달 앱 콘텐츠 개발과 운영에 필요한 기초적인 자료를 제공하고자 하였다. 연구의 조사대상과 공간적 범위는 최근 3개월이내 배달 앱을 이용한 경험이 있는 전국의 20세 이상 남녀 내국인 거주자로 정하였으며, 조사대상자 중에서 배달의 민족, 요기요, 배달통을 통해 음식을 주문한 경험이 있는 외식소비자들을 대상으로 설문조사를 하였다. 연구결과, 배달 앱 서비스품질의 디자인과 공감성은 각성에 긍정적인 영향을 미치며, 디자인과 신뢰성은 즐거움에 긍정적 영향을 미치는 것으로 나타났다. 배달 앱 서비스품질의 정보성과 이동성은 앱 이용의도에 긍정적인 영향을 미치는 것으로 나타났다. PAD의 즐거움은 앱 이용의도에 긍정적인 영향을 미치나, 각성은 아무 영향력이 없는 것으로 나타났다. 외식소비자들이 배달 앱을 지속적으로 이용하도록 유도하기 위해서는 디자인과 신뢰성, 정보성, 이동성이 매우 중요한 요인임을 제시하였다.