• Journal of the korean society of oceanography
• /
• 제33권3호
• /
• pp.90-99
• /
• 1998

Butyltin and phenyltin residues were quantified in seawater and biota of the Chinhae Bay System, Korea in 1995. Butyltin compounds were detected in all seawater and biota samples, whereas phenyltin compounds were found only in the biota samples. Tributyltin (TBT) concentrations in seawater ranged from < 8-35 ng Sn/l. Tributyltin concentrations in Crassostyea gigas and Thais clavigera ranged from 95-885 and 23-414 ng Sn/g, respectively, Triphenyltin(TPhT) concentrations in each species ranged 155-678 and 46-785 ng Sn/g, respectively. Spatial distribution of TBT was closely related to boating and dry-docking activities. However, spatial distribution of TPhT was not consistent with that of TBT. The biological concentration factor for TBT in C. gigas was about 25000 that is four times greater than that of T. clavigera. Butyl- to phenyltin concentration ratio was greater than one in C. gigas, but that in T. clavigera was less than one. Major tissues of C. gigas also showed different accumulation patterns for butyl- and phenyltin compounds. Furthermore, 19 and 28% of total body burdens of TBT and TPhT were found in gonadal mass of C. gigas just prior to spawning.

• 수산해양기술연구
• /
• 제40권2호
• /
• pp.144-148
• /
• 2004

해저에 설치된 파이프에서 분출되는 기포에 의해 형성된 강한 수평압력분포를 이용하여 선박을 신속 하고 정밀하게 유도, 정박시키는 도선시스템으로 항구, 협수로, 해협 등과 같이 복잡한 수상, 수중 장애물 지역에서 선박을 신속하고 정밀하게 유도함과 동시에 협소한 부두에 안전하게 선박을 정박시키기 위하여 본 도선 시스템을 고안하였다.

• 한국정밀공학회지
• /
• 제33권3호
• /
• pp.235-242
• /
• 2016

The purpose of this study is an attempt to improve the functionality of a conventional Fused Deposition Modeling (FDM) process using the Automatic Tool Changer (ATC) to perform multimaterial production and post-processing. Hybrid-FDM means a fusion of an Additive Manufacturing process and grinding process using the ATC system. In order to enhance the potentiality of production capacity for multi-material fabrication and surface roughness improvement, two extrusion tools and one grinding tool system are suggested. A pneumatic chuck is attached on a moving platform in the XY axes plane and an extrusion head and grinding head are placed in a docking station, allowing for a quick changeover with each other. Therefore, the manufacturing lead time can be reduced efficiently for the fabrication of a product.

• Archives of Plastic Surgery
• /
• 제48권6호
• /
• pp.577-582
• /
• 2021

Robot-assisted surgery is evolving to incorporate a higher number of minimally invasive techniques. There is a growing interest in robotic breast reconstruction that uses autologous tissue. Since a traditional latissimus dorsi (LD) flap leads to a long donor scar, which can be an unpleasant burden to patients, there have been many attempts to decrease the scar length using minimally invasive approaches. This study presents the case of a patient who underwent a robot-assisted nipple-sparing mastectomy followed by immediate breast reconstruction with an LD flap using a single-port robotic surgery system. With the assistance of a single-port robot, a simple docking process using a short and less visible incision is possible. Compared to multiport surgery systems, single-port robots can reduce the possibility of collision between robotic arms and provide a clear view of the medial border of the LD where the curvature of the back restricts the visual field. We recommend the use of single-port robots as a minimally invasive approach for harvesting LD flaps.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2002년도 춘계학술대회 논문집
• /
• pp.243-250
• /
• 2002

According to Ocean Korea 21, a basic plan established by the Ministry of Maritime Affairs and Fisheries (MOMAF) of Korea in May 2000, Korea Research Institute of Ships and Ocean Engineering (KRISO) proposed a program for the development of a deep-sea unmanned underwater vehicle (UUV) to explore deep sea for scientific purpose. KRISO has launched a project in May 2001 under the support of MOMAF. The deep-sea unmanned underwater vehicle will be applied to scientific researches in deep-sea as well as in shallow water. For operation of underwater vehicles in shallow water near the Korean Peninsula, a special design is required because of strong tidal current. In addition, MOMAF requires the vehicle to be designed for the purpose of long range survey, a long-term observation, and precise works in a specific area. Thus, KRISO has planned to design the system with the functional combination of both ROV and AUV. This paper presents the design of the deep-sea unmanned underwater vehicle.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2004년도 학술대회지
• /
• pp.249-256
• /
• 2004

KRISO/KORDI is currently developing a deep-sea unmanned underwater vehicle (UUV) system which is composed of a launcher, an ROV, and an AUV. Two USBL acoustic positioning systems will be used for UUV's navigation. One is for the deep sea positioning of all three vehicles and the other is for AUV's guidance to the docking device on the launcher. In order to increase the position accuracy MFSK(Multiple Frequency Shift Keying) broadband signal will be used. As the first step to the implementation of a USBL system, this paper studies USBL positioning algorithm using MFSK signals. Firstly, the characteristics of MFSK signal is described with various MFSK parameters: number of frequencies, frequency step, center frequency, and pulse length. Time and phase delays between two received signals are estimated by using cross-correlation and cross-spectrum methods. Finally an USBL positioning algorithm is derived by converting the delays to difference of distances and applying trigonometry. The simulation results show that the position accuracy is improved highly when both cross-correlation and cross-spectrum of MFSK signals are used simultaneously.

• 한국HCI학회논문지
• /
• 제4권1호
• /
• pp.17-27
• /
• 2009

컴퓨터를 사용한 협업 시스템은 인터넷을 통하여 가상공간에서 여러 명의 사용들이 협력하여 작업을 할 수 있는 시스템을 의미한다. 특히, 협업 가상현실 시스템은 실제로 경험하기 힘든 작업을 사이버 공간에서 가능하게 하여 다양한 과학기술 분야 및 문화기술 분야에 적용이 되고 있다. 하지만 기존의 협업 가상현실 시스템들은 같은 시간대에 동기화되어 이루어지는 작업에만 중점을 두고 있어 시간과 장소의 차이에 따라 이루어지는 다양한 형태의 협업 작업들은 지원 하지 못하고 있다. 본 연구에서는 이러한 문제를 해결하기 위해 동기식 및 비동기식 원격 차이에 따른 협업 작업을 분류하고 이에 따른 동기식 및 비동기식 원격 협업 작업을 지원 해주는 시스템을 제안 한다. 제안된 시스템은 생명공학 분야의 중요한 실험인 도킹 시뮬레이션 및 구조 결정학 분석 실험에 적용 되었다. 실험과정에서는 선정된 분자 시뮬레이션 실험 과정을 본 논문에서 제안한 동기식 및 비동기식 원격 협업 작업을 하는 경우와 일반적인 단일 작업을 하는 경우에 걸리는 시간과 성능을 비교 하였다.

• 컴퓨터교육학회논문지
• /
• 제12권4호
• /
• pp.57-64
• /
• 2009

단백질 구조 비교는 각 단백질에 존재하는 수많은 원자들을 처리해야 하므로 많은 컴퓨팅 자원을 요구하는 작업이다. 이러한 작업을 처리하기 위한 접근법으로써 그리드 환경에서 시간 소모가 큰 계산 작업을 분산 처리하는 것이 널리 사용되어 왔다. 그러나 이러한 그리드 환경을 통제하는 것은 비전문가들에게 쉽지 않을 수 있다. 본 논문에서는 비전문가들도 쉽게 그리드 환경을 통제할 수 있는 JXTA 기반의 단백질 구조 비교 시스템을 제안한다. 쿼리 단백질과 비슷한 단백질들을 찾기 위해 사전처리 단계 와 인식단계로 구성된 기하학적 해싱 알고리즘이 사용되었다. 실험 결과에 의하면 주어진 쿼리 단백질 구조와 일치하는 단백질 구조를 시스템이 정확히 찾고 또한 제안된 시스템은 쉽게 단백질 다킹 문제를 해결하도록 확장될 수도 있다. 본 논문에서 제안하는 시스템은 비전문가들, 특히 생물학이나 화학을 전공하는 대학생들처럼 일반적으로 분산 시스템에 대한 숙련된 지식이 없는 사용자들에게 도움이 되리라 기대된다.

• 한국항해항만학회:학술대회논문집
• /
• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.2
• /
• pp.203-208
• /
• 2006

The main research conducted previously on GPS ionosphere in China is first introduced. Besides, the current investigations include as follows: (1) GPS-based spatial environmental, especially the ionosphere, monitoring, modeling and analysis, including ground/space-based GPS ionosphere electron density (IED) through occultation/tomography technologies with GPS data from global/regional network, development of a GNSS-based platform for imaging ionosphere and atmosphere (GPFIIA), and preliminary test results through performing the first 3D imaging for the IED over China, (2) The atmospheric and ionospheric modeling for GPS-based surveying, navigation and orbit determination, involving high precisely ionospheric TEC modeling for phase-based long/median range network RTK system for achieving CM-level real time positioning, next generation GNSS broadcast ionospheric time-delay algorithm required for higher correction accuracy, and orbit determination for Low-Earth-orbiter satellites using single frequency GPS receivers, and (3) Research products in applications for national significant projects: GPS-based ionospheric effects modeling for precise positioning and orbit determination applied to China's manned space-engineering, including spatial robot navigation and control and international space station intersection and docking required for related national significant projects.

• Journal of Ginseng Research
• /
• 제48권4호
• /
• pp.395-404
• /
• 2024

Background: Ginsenoside Rg₁ (Rg₁) is one of the main active components in Chinese medicines, Panax ginseng and Panax notoginseng. Research has shown that Rg₁ has a protective effect on the cardiovascular system, including anti-myocardial ischemia-reperfusion injury, anti-apoptosis, and promotion of myocardial angiogenesis, suggesting it a potential cardiovascular agent. However, the protective mechanism involved is still not fully understood. Methods: Based on network pharmacology, ligand-based protein docking, proteomics, Western blot, protein recombination and spectroscopic analysis (UV-Vis and fluorescence spectra) techniques, potential targets and pathways for Rg₁ against myocardial ischemia (MI) were screened and explored. Results: An important target set containing 19 proteins was constructed. Two target proteins with more favorable binding activity for Rg₁ against MI were further identified by molecular docking, including mitogen-activated protein kinase 1 (MAPK1) and adenosine kinase (ADK). Meanwhile, Rg₁ intervention on H9c2 cells injured by H₂O₂ showed an inhibitory oxidative phosphorylation (OXPHOS) pathway. The inhibition of Rg₁ on MAPK1 and OXPHOS pathway was confirmed by Western blot assay. By protein recombination and spectroscopic analysis, the binding reaction between ADK and Rg₁ was also evaluated. Conclusion: Rg₁ can effectively alleviate cardiomyocytes oxidative stress injury via targeting MAPK1 and ADK, and inhibiting oxidative phosphorylation (OXPHOS) pathway. The present study provides scientific basis for the clinical application of the natural active ingredient, Rg₁, and also gives rise to a methodological reference to the searching of action targets and pathways of other natural active ingredients.