• CELLMED
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• v.8 no.4
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• pp.19.1-19.5
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• 2018

A majority of the peoples in Indian cities depend on high fat diet, smoking, ghutka chewing and improper sleep, these all are lifestyle changes, can cause ischemic heart disease. Globally, ischemic heart disease (IHD) is the leading killer. Unani System of medicine not only provides well-based medical cures for diseases, but its holistic approaches as it possess unique principles of diet, lifestyle and particularly therapeutics, to balance and enrich all aspects of physiology and psyche. All diseases are the result of poor management of the six governing (or essential) factors, beyond the ability of physics or Tabiat to maintain and restore homeostasis. In this context, lifestyle diseases can be prevented by conscious changes to the person's diet, behavior and environment. The holistic approach of Unani medicine is well placed to cover the two main pillars of lifestyle diseases, namely, prevention and treatment. In this paper, we report on the prevalence of CAD in patients with known diagnosis of CAD and try to find out its relationship with different lifestyle changes.

• Journal of Microbiology and Biotechnology
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• v.33 no.1
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• pp.123-126
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• 2023

The prevalence of candidiasis, a contagious disease with high morbidity and mortality, has sharply increased globally over the last two decades. Candida albicans can cause serious infections in patients with weak immunity and in recipients of prolonged antibiotic treatment. Consequently, rapid and accurate identification of species can play an important role in the treatment of candidiasis. Here, we investigated the positive rate and infection trend of C. albicans according to age, specimen type, and sex using multiplex real-time polymerase chain reaction-based testing of samples collected for the diagnosis of sexually transmitted diseases in Korea between 2018 and 2020. When the type of specimen collected was a swab, the positive rate of C. albicans was higher among younger women, and tended to decrease with age. Analysis of swab samples revealed higher positive rates than urinalysis. The reduction trend in positive rates by age was comparable between the overall samples and urine specimens. Among male patients, the positive rate did not differ substantially across the various types of specimens collected. Previous studies have shown a higher prevalence of non-albicans Candida species than C. albicans in clinical specimens, and exclusion of the former from our analysis may be a limitation of this study. However, our findings contribute significantly to the literature because globally, there is a paucity of epidemiological studies using molecular techniques to detect C. albicans in sexually transmitted disease test samples.

• Food Science of Animal Resources
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• v.38 no.2
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• pp.209-223
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• 2018

The effect of high egg intake on metabolic syndrome (MetS), a major risk factor for cardiovascular disease (CVD), has not been clearly elucidated. This study was conducted to review the literature related to egg consumption and the risk of metabolic disease as well as to examine the association between high egg intake and MetS in Korean adults. A literature review was conducted using published papers in PubMed and EMBASE through December 2017. We have reviewed 26 articles, which were associated with egg consumption and metabolic diseases, and found that the results were controversial. Therefore, we analyzed data from 23,993 Korean adults aged 19 yrs and older. MetS was defined based on criteria from the Adult Treatment Panel III. Egg consumption of 4-6 times/wk and 1 time/day were significantly associated with reduced prevalence of MetS (Odds ratio (OR)=0.82; 95% Confidence interval (CI)=0.71-0.95 for 4-6 times/wk, OR=0.83; 95% CI=0.69-0.99 for 1 time/day) compared to those who consumed eggs less than once monthly. However, consuming two or more eggs per day was not associated with MetS. As for the components of MetS, an egg intake of once daily decreased the prevalence of abdominal obesity and an intake of 2-7 eggs weekly was shown to prevent a reduction in the high-density lipoprotein cholesterol levels. This study suggests that while consuming eggs 4-7 times weekly is associated with a lower prevalence of MetS, consuming two or more eggs daily is not associated with a reduced risk for MetS.

• Korean Journal of Health Education and Promotion
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• v.24 no.1
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• pp.29-43
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• 2007

Objectives: The purpose of this study was to investigate the obesity prevalence and to test the obesity prevalence and health status, socio-demographic factors and lifestyle such as smoking and drinking habits, diet habit and physical activity of rural residents in Korea. Methods: The interview survey was performed in November 2005 with structured questionnaires to 518 respondents of the residents who lived in Jindo-Gun of Jeonnam province. The questionnaire was the abridged Scale of the Health and Nutrition Survey and health status as the morbidity, subjective health status and health examination. The covariate, F-test or t-test, and Chi-squire method were used for some of the cross-sectional data. Results: The 518adults respondents were composed of 49.8% male and 50.2% female. Average weight of male was $67.4{\pm}8.36kg$, and average weight of female was $56.5{\pm}6.92kg$. The obesity rate was 20.7%, and the lower weight rate was 2.9%. About the subjective health status that 43.2% of the respondents have been answered not good health status, 70.8% of the respondents have been health examination. 56.0% of the respondents had disease, while 49.0% of the respondents had chronic disease, and 11.1% of the respondents had acute disease. The obesity rate and general characteristics(age, education level) was positively correlated. And while the relationships were positive between obesity rate and between lifestyle(overeating, drinking, dining-out). Conclusion: These results suggested that education programs of the health habits such as drinking, physical exercise and eating habits were necessities for the residents of rural area. Further research would be required to specify the necessities and operation researches.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5245-5249
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• 2012

Background: Opisthorchis viverrini infection is a serious public-health problem in Southeast Asia especially in Lao PDR and Thailand. It is associated with a number of hepatobiliary diseases and the evidence strongly indicates that liver fluke infection is the major etiology of cholangiocarcinoma. Objectives: This study aimed to determine actual levels of Opisthorchis viverrini infection in Nakhon Ratchasima province, Northeast Thailand. Methods: A cross-sectional survey was conducted during a one year period from October 2010 to September 2011. O. viverrini infection was determined using a modified Kato's thick smear technique and socio-demographic data were collected using predesigned semi-structured questionnaires. Results: A total of 1,168 stool samples were obtained from 516 males and 652 females, aged 5-90 years. Stool examination showed that 2.48% were infected with O. viverrini. Males were slightly more likely to be infected than females, but the different was not statistically significant. O. viverrini infection was most frequent in the 51-60 year age group and was found to be positively associated with education and occupation. Positive results were evident in 16 of 32 districts, the highest prevalence being found in Non Daeng with 16.7%, followed by Pra Thai with 11.1%, Kaeng Sanam Nang with 8.33%, and Lam Ta Men Chai (8.33%) districts. Conclusion: This study indicates that O viverrini is still a problem in some areas of Nakhon Ratchasima, the patients in this study bing suitable for the purpose of monitoring projects.

• Journal of Nutrition and Health
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• v.44 no.5
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• pp.406-415
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• 2011

Recent studies have shown that high consumption of processed meat may be associated with increasing risk of metabolic syndrome, which have been suggested as a predictor of diabetes and cardiovascular disease. However, limited studies have investigated this association in Korean population. The purpose of this study was to investigate the cross-sectional association between processed meat/unprocessed (beef, pork, chicken) intakes and the prevalence of metabolic syndrome. Using data from 2007-2008 Korean National Health and Nutrition Examination Survey (KNHANES), we analyzed data including 5,545 men and women who were aged older than 20 years, and who were free of chronic disease such as hypertension, type 2 diabetes and cardiovascular disease. Subjects who frequently consumed processed meat tended to be younger and more likely to be current smokers. In addition, men were more likely to consume processed meat than women. Although higher processed/unprocessed meat intakes were significantly associated with the lower risk of metabolic syndrome in a crude model, these associations were no longer significant after adjustment for potential confounding factors. For example, comparing subjects in the highest intake quartile of processed meat with the lowest intake group, the multivariate-adjusted odds ratio (OR) of metabolic syndrome was 0.92 (95% CI: 0.58-1.46) for processed meat, 1.09 (95% CI: 0.76-1.56) for beef, 1.10 (95% CI: 0.74-1.62) for pork and 0.75 (95% CI: 0.51-1.12) for chicken. In conclusion, we found no evidence of any adverse effects of frequent processed or unprocessed meat intakes on the prevalence of metabolic syndrome among Korean adults at the exposure levels seen in this study.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10957-10960
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• 2015

Background: The CYP2C19 genotype has been found to be an important factor for peptic ulcer healing and H. pylori eradication, influencing the efficacy of proton pump inhibitors (PPIs) and the pathogenesis of gastric cancer. The aim of this study was to investigate clinical correlations of the CYP2C19 genotype in patients with gastritis, peptic ulcer disease (PUD), peptic ulcer bleeding (PUB) and gastric cancer in Thailand. Materials and Methods: Clinical information, endoscopic findings and H. pylori infection status of patients were assessed between May 2012 and November 2014 in Thammasat University Hospital, Thailand. Upper GI endoscopy was performed for all patients. Five milliliters of blood were collected for H. pylori serological diagnosis and CYP2C19 study. CYP2C19 genotypes were determined by polymerase chain reaction (PCR) and restriction fragment length polymorphism analysis (RFLP) and classified as rapid metabolizer (RM), intermediate metabolizer (IM) or poor metabolizer (PM). Results: A total of 202 patients were enrolled including 114 with gastritis, 36 with PUD, 50 with PUB and 2 with gastric cancer. Prevalence of CYP2C19 genotype was 82/202 (40.6%) in RM, 99/202 (49%) in IM and 21/202 (10.4%) in PM. Overall H. pylori infection was 138/202 patients (68.3%). H. pylori infection was demonstrated in 72% in RM genotype, 69.7% in IM genotype and 47.6% in PM genotype. Both gastric cancer patients had the IM genotype. In PUB patients, the prevalence of genotype RM (56%) was highest followed by IM (32%) and PM(12%). Furthermore, the prevalence of genotype RM in PUB was significantly greater than gastritis patients (56% vs 36%: p=0.016; OR=2.3, 95%CI=1.1-4.7). Conclusions: CYP2C19 genotype IM was the most common genotype whereas genotype RM was the most common in PUB patients. All gastric cancer patients had genotype IM. The CYP2C19 genotype RM might be play role in development of PUD and PUB. Further study in different population is necessary to verify clinical usefulness of CYP2C19 genotyping in development of these upper GI diseases.

• Journal of Preventive Medicine and Public Health
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• v.50 no.1
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• pp.18-28
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• 2017

Objectives: Low birth weight (LBW) is a major public health concern, especially in developing countries, and is frequently related to child morbidity and mortality. This study aimed to identify key determinants that influence the prevalence of LBW in selected developing countries. Methods: Secondary data analysis was conducted using 10 recent Demography and Health Surveys from developing countries based on the availability of the required information for the years 2010 to 2013. Associations of demographic, socioeconomic, community-based, and individual factors of the mother with LBW in infants were evaluated using multivariate logistic regression analysis. Results: The overall prevalence of LBW in the study countries was 15.9% (range, 9.0 to 35.1%). The following factors were shown to have a significant association with the risk of having an LBW infant in developing countries: maternal age of 35 to 49 years (adjusted odds ratio [aOR], 1.7; 95% confidence interval [CI], 1.2 to 3.1; p<0.01), inadequate antenatal care (ANC) (aOR, 1.7; 95% CI, 1.1 to 2.8; p<0.01), illiteracy (aOR, 1.5; 95% CI, 1.1 to 2.7; p<0.001), delayed conception (aOR, 1.8; 95% CI, 1.4 to 2.5; p<0.001), low body mass index (aOR, 1.6; 95% CI, 1.2 to 2.1; p<0.001) and being in the poorest socioeconomic stratum (aOR, 1.4; 95% CI, 1.1 to 1.8; p<0.001). Conclusions: This study demonstrated that delayed conception, advanced maternal age, and inadequate ANC visits had independent effects on the prevalence of LBW. Strategies should be implemented based on these findings with the goal of developing policy options for improving the overall maternal health status in developing countries.

• Journal of muscle and joint health
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• v.8 no.2
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• pp.250-261
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• 2001

Alternative therapy for rheumatoid arthritis has become worldwide phenomenon this decade without scientific validation. This study was undertaken to explore the prevalence, patterns of use, and perceived efficacy of alternative therapies by patients attending a rheumatology clinic. We conducted a crossectional survey of 142 RA patients with structured questionnaire at outpatient rheumatic clinic from July to August in 2001. Results of this study were summarized as follows : 1. 85.9% of subjects were woman. Mean age was 49.97years, duration of rheumatoid arthritis was 5.6years. Mean pain score was 5.29cm. 2. 74.6% of subjects perceived rheumatoid arthritis as a controllable disease. 31% of patients combined medical treatments with alternative therapies. 58.5% of patients perceived that combining medical treatments with alternative therapies is the most effective strategy in controlling disease. 3. 77.5% had used more than one alternative therapy since the diagnosis was made. The major reason of discontinuation of use was no effect for the treatment of their disease. 4. 34.5% were currently using an alternative therapies and 50.9% were going to use alternative therapies in future. 5. 42.7% reported that alternative therapies was effective and only 3.6% reported side effects. 6. The perceived effect score was 3.14cm in general expecially the physiological score 2.91cm, psychological score 4.16cm. In conclusion, our results demonstrate a high use of alternative therapies by rheumatoid arthritis patients. And the perceived effect score of physiological aspect was not higher than one of psychological aspect. Therefore it should be considered in education program for the use of alternative therapies.

• Korean Journal of Veterinary Service
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• v.33 no.1
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• pp.67-74
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• 2010

To reduce an economic loss by swine disease, this study was designed to provide helpful data which are particularly useful for each individual farm. From february to December 2009, a total of 18,173 slaughter pigs (612 herds) were randomly sampled, which were produced just in southern region of Gyeonggi-do. We examined all of them for the slaughter lesions of 8 kind diseases such as swine enzootic pneumonia (SEP), pleuritis (PL), pleuropneumonia (PP), white milk spot in liver (WMS), papular dermitis (PD), pericarditis (PC), ileitis (IL) and peritonitis (PT). Twenty four percentages (4431/18173 pigs) of the examined pigs had no lesions about 8 kind diseases. Among the pigs with lesions, the numbers of the pigs with just one lesion were 7,637(42%), followed by 4,551(25%) pigs with 2 lesions. Average prevalence of pigs were 56.5% (10288/18173 pigs) in SEP, followed by 34% in PL, 12.4% in PP, 10.1% in WMS, 6.1% in PD, 4.7% in PC, 0.1% in IL and PT, respectively. Each prevalence of SEP, PL, PP and PD was higher in spring than in winter, respectively (P<0.01). Among the pigs (n=6,105) with 2 or more than 2 kinds of lesions the top (55.5%) was the pigs with SEP and PL, and the second was 1,179 (19.3%). Swine enzootic pneumonia was considered as one of the more likely risk factors for initiation or/and acceleration of other diseases such as PL, PP, WMS and PD. The lesion of SEP was relatively severe since the pigs with late stage were more (7,277 pigs) than those with early stage.